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  1. 961

    The Application of Single-Cell RNA Sequencing in Vaccinology by Andrés Noé, Tamsin N. Cargill, Carolyn M. Nielsen, Andrew J. C. Russell, Eleanor Barnes

    Published 2020-01-01
    “…Single-cell RNA sequencing allows highly detailed profiling of cellular immune responses from limited-volume samples, advancing prospects of a new era of systems immunology. …”
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    Article
  2. 962

    Transcriptomic Profiling of Human Placental Trophoblasts in Response to Infection with Enterococcus faecalis by Qianglai Tan, Feng Xu, Hengyi Xu, Liang Qiu, Xueying Tao, Hua Wei

    Published 2018-01-01
    “…These differentially expressed genes (DEGs) are involved in apoptosis, stress and stimulus response, placental and embryonic development, immune response, and cell adhesion. Therefore, these results provide information on the molecular mechanisms that E. faecalis invasion can trigger to cause adverse pregnancy outcomes.…”
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  3. 963

    CD47/SIRPα axis: bridging innate and adaptive immunity by Sjoerd H van der Burg, Anneloes van Duijn, Ferenc A Scheeren

    Published 2022-07-01
    “…Myeloid immune cells are frequently present in the tumor environment, and although they can positively contribute to tumor control they often negatively impact anticancer immune responses. One way of inhibiting the positive contributions of myeloid cells is by signaling through the cluster of differentiation 47 (CD47)/signal regulatory protein alpha (SIRPα) axis. …”
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  4. 964

    Data Mining Mycobacterium tuberculosis Pathogenic Gene Transcription Factors and Their Regulatory Network Nodes by Guangxin Yuan, Yu Bai, Yuhang Zhang, Guangyu Xu

    Published 2018-01-01
    “…It was predicted that IL-6, JUN, and TP53, along with transcription factors SRC, TNF, and MAPK14, could regulate the immune response, with their function being extracellular region activity and protein binding during infection with M. tuberculosis.…”
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    Article
  5. 965

    Structure simulation-based comparison of active site variations in fungal ornithine decarboxylases by Min Jeong Kim, Jeong Ho Chang

    Published 2025-12-01
    “…Polyamines play crucial roles in various biological processes, including cell proliferation and differentiation, immune response modulation, and signal transduction. Ornithine decarboxylase (ODC) initiates polyamine biosynthesis by catalyzing the conversion of ornithine to putrescine in a pyridoxal phosphate (PLP)-dependent manner. …”
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  6. 966

    3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists by Ji Hwan Kim, Seunghyun Ahn, Dongsoo Koh, Young Han Lee, Yoongho Lim, Soon Young Shin

    Published 2023-01-01
    “…These data suggest that compound 6 induces an innate immune response by agonizing TLR7 activity in THP1 human monocytic cells. …”
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    Article
  7. 967

    Inborn errors of immunity (primary immunodeficiencies) by Vy H. D. Kim, Julia E. M. Upton, Beata Derfalvi, Kyla J. Hildebrand, Christine McCusker

    Published 2025-01-01
    “…The treatment of IEIs is complex and generally requires both supportive and definitive strategies, including but not limited to, immunoglobulin replacement therapy, antibiotic prophylaxis, immune response modifiers, and hematopoietic stem cell transplantation. …”
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    Article
  8. 968

    Microbiome interplays in the gut-liver axis: implications for liver cancer pathogenesis and therapeutic insights by Xuran Wang, Bin Zhang, Runqiu Jiang

    Published 2025-01-01
    “…In this review, we present the concept of Gut-Liver Axis and its function in the mutual influence between gut microbiota and PLC from several aspects in which we will focus on the structure of gut barrier and the functional influences the gut microbiota have on the immune response and metabolic changes on human liver. …”
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    Article
  9. 969

    PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors by Francesco Dituri, Antonio Mazzocca, Gianluigi Giannelli, Salvatore Antonaci

    Published 2011-01-01
    “…The phosphatidylinositol 3-kinase (PI3K) pathway regulates multiple cellular processes which underlie immune responses against pathogens or malignant cells. …”
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  10. 970

    Pro-angiogenic effects of Guo Min decoction in a zebrafish model by Ping-Hsun Lu, Sheng-Fen Tung, Chi-Chung Wen, Ching-Yuan Huang, Jhih-Wei Huang, Chih-Hsin Chen, Yau-Hung Chen

    Published 2025-01-01
    “…Although GMD treatment was reported to treat allergy-associated symptoms by regulating the immune response, the rationale between GMD treatment and angiogenesis has not been reported yet. …”
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    Article
  11. 971

    Fatal H1N1-Related Acute Necrotizing Encephalopathy in an Adult by Yu-Jin Lee, D. Scott Smith, Vivek A. Rao, Robert D. Siegel, Jon Kosek, Carol A. Glaser, Alexander C. Flint

    Published 2011-01-01
    “…This case of fatal ANE in an adult is consistent with the hypothesis generated from pediatric cases that the host immune response, and not direct viral invasion of the CNS, is responsible for pathogenesis of ANE.…”
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    Article
  12. 972

    Exploring the link between gut health, diet, and food allergy by Magdalena Klimczak, Barbara Rymarczyk, Radosław Gawlik

    Published 2024-09-01
    “…Changes in the gut microbiota, whether due to dietary habits, fiber consumption, the hygiene hypothesis, proton pump inhibitors, non-steroidal anti-inflammatory drugs, antibiotic use, supplementation and other factors, can potentially influence the immune response leading to the development and severity of food allergy. …”
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  13. 973

    Hubungan Nilai Laju Endap Darah (LED) dengan Kadar C-Reactive Protein (C-RP) pada Pasien Positif Covid-19 by Yumna Tahani Tsamarah, I Gusti Ayu Nyoman Danuyanti, Siti Zaetun

    Published 2022-01-01
    “…SARS-CoV-2 infection is a systemic infection that significantly affects hematopoiesis and the patient's immune response. Drastic increase in the production of proinflammatory cytokines like interleukin-6 (IL-6) play a role in mechanism of lymphopenia in COVID-19. …”
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    Article
  14. 974

    Mannose-binding lectin gene sequence data in Kelantan population by Muhamad Aidil Zahidin, Noor Haslina Mohd Noor, Muhammad Farid Johan, Abu Dzarr Abdullah, Zefarina Zulkafli, Hisham Atan Edinur

    Published 2024-04-01
    “…Abstract The human mannose-binding lectin (MBL) gene encodes a polymorphic protein that plays a crucial role in the innate immune response. Human MBL deficiency is associated with immunodeficiencies, and its variants have been linked to autoimmune and infectious diseases. …”
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    Article
  15. 975

    The Tuberculous Granuloma: An Unsuccessful Host Defence Mechanism Providing a Safety Shelter for the Bacteria? by Mayra Silva Miranda, Adrien Breiman, Sophie Allain, Florence Deknuydt, Frederic Altare

    Published 2012-01-01
    “…One of the main features of the immune response to M. Tuberculosis is the formation of an organized structure called granuloma. …”
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    Article
  16. 976

    Gene Carriers and Transfection Systems Used in the Recombination of Dendritic Cells for Effective Cancer Immunotherapy by Yu-Zhe Chen, Xing-Lei Yao, Yasuhiko Tabata, Shinsaku Nakagawa, Jian-Qing Gao

    Published 2010-01-01
    “…They play a vital role in the initiation of immune response by presenting antigens to T cells and followed by induction of T-cell response. …”
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    Article
  17. 977

    Immunoinflammatory Response to Acute Noise Stress in Male Rats Adapted with Different Exercise Training by Elaheh Farahbakht, Yousra Alsinani, Mohammadamin Safari, Martin Hofmeister, Rasoul Rezaie, Alireza Sharifabadi, Maryam Koushkie Jahromi

    Published 2023-12-01
    “…Conclusion: In response to noise stress, previous exercise, especially HIIT, increased stress while did not increase inflammatory and innate immune response.…”
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    Article
  18. 978

    Hepatitis E rORF2p Stimulated and Unstimulated Peripheral Expression Profiling in Patients with Self-Limiting Hepatitis E Infection by Sanjay B. Rathod, Anuradha S. Tripathy

    Published 2014-01-01
    “…The observed upregulations of inhibitory, integrin, activatory, and Treg-associated cytokine genes on the PBMCs of acute HEV patients complemented by their frequency data suggest them as the major players in the fine-tuning of immune response in self-limiting hepatitis E infection.…”
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  19. 979

    Dysregulation of NK and CD8+T Cells by the Microbiota Promotes the Progression of Lung Cancer by Shouxin Hu, Yanfang Zha, Wenwen Yang, Kele Cui, Min Cheng

    Published 2022-01-01
    “…Alterations in the amount and dominant species of the microbiota can reshape the immune response of the body and lead to a variety of lung diseases, including cancer. …”
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    Article
  20. 980

    Immune System in the Brain: A Modulatory Role on Dendritic Spine Morphophysiology? by Oscar Kurt Bitzer-Quintero, Ignacio González-Burgos

    Published 2012-01-01
    “…In addition, astrocytes, oligodendrocytes, endothelial cells, and, to a lesser extent, neurons are implicated in the immune response in the central nervous system. By modulating synaptogenesis, microglia are most specifically involved in restoring neuronal connectivity following injury. …”
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