Epstein-Barr Virus and Systemic Lupus Erythematosus by Anette Holck Draborg, Karen Duus, Gunnar Houen

“…This gives rise to enhanced apoptosis and amplified cellular waste load resulting in activation of an immune response and development of EBV-directed antibodies and autoantibodies to cellular antigens.…”
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Toll-Like Receptor-Based Strategies for Cancer Immunotherapy by Saghar Pahlavanneshan, Ali Sayadmanesh, Hamidreza Ebrahimiyan, Mohsen Basiri

“…There are plenty of data on the pharmacological targeting of TLR signaling using agonist molecules that boost the antitumor immune response. A recent body of research has also demonstrated promising strategies for improving the cell-based immunotherapy methods by inducing TLR signaling. …”
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Identification of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma (HNSC) for the Exploration of Immunotherapy and Prognosis by Chunli Huang, Jifeng Liu

“…The potential pathways that are associated with ZAP70 were found to have included adaptive immune response, response to oxidative stress, DNA replication, and lipid binding. …”
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COVID-19-Induced Fatal Thrombotic Thrombocytopenic Purpura in a Healthy Young Patient by Mariana Codevila Buere Pereira, Bruna Ruschel, Bruna Schneider, Vitor Salomão Gonçalves Melo de Melgar, Tatiana Helena Rech

“…TTP can be an unusual presentation of COVID-19 disease mediated by the virus-induced immune response. We report a case of a healthy young patient presenting with the classic TTP pentad a few days after a diagnosis of COVID-19 confirmed by a positive SARS-CoV-2 RT-PCR test. …”
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Adverse Immunologically Mediated Oral Mucosal Reactions to Systemic Medication: Lichenoid Tissue Reaction/Interface Dermatitis-Stomatitis, Autoimmune Vesiculobullous Disease, and I... by R. A. G. Khammissa, R. Chandran, A. Masilana, J. Lemmer, L. Feller

“…The type of hypersensitivity immune response generated, whether antibody mediated or T cell mediated, or an immune complex reaction is determined by multiple factors, including the molecular characteristics of the allergen, the route of administration of the medication, the manner of presentation of the allergen by antigen-presenting cells to naïve T cells, the repertoire of the T cell receptors, and the cytokine profile within the microenvironment. …”
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Discovering the interactome, functions, and clinical relevance of enhancer RNAs in kidney renal clear cell carcinoma by Zhaohui Sun, Haojie Du, Xudong Zheng, Hepeng Zhang, Huajie Hu

“…Our findings revealed that up-regulated eRNAs in KIRC potentially regulate immune response and hypoxia pathways, while down-regulated eRNAs may impact ion transport, cell cycle, and metabolism. …”
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Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis by Elisabetta Volpe, Luca Battistini, Giovanna Borsellino

“…The identification of the features endowing Th17 cells with high pathogenicity in MS is of particular interest, and discoveries in Th17 cell biology and function could lead to the design of new strategies aimed at modulating the immune response in MS. Here, we will discuss recent advances in this field, with particular focus on the mechanisms conferring pathogenicity in MS and their potential modulation.…”
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Sarcoid-Like Mediastinal Lymphadenopathy in Gynecologic Malignancy by Bilal H. Lashari, Megumi Asai, Gissele Randleman, Martha Sack, Rajeshkumar Patel

“…Noncaseating granulomas are seen surrounding tumors with varying frequency, possibly as part of an immune response to tumor cells. However, data about the association of sarcoid with gynecologic malignancy is sparse. …”
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EFFECT OF p30 RECOMBINANT PROTEIN ON AFRICAN SWINE FEVER VIRUS IN VITRO REPRODUCTION by Ali Mazloum, I. Yu. Zhukov, A. S. Pershin, A. S. Igolkin, N. N. Vlasova

“…However, it is necessary to study the function of definite viral proteins, their role in immune response morphogenesis and induction to determine the components to be included into ASF protection drugs. …”
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Immunity in the Cervix: Interphase between Immune and Cervical Epithelial Cells by Jorgelina Barrios De Tomasi, Michael Makokha Opata, Chishimba Nathan Mowa

“…The cytokines subsequently recruit subsets of immune cells appropriate to a particular immune context and response, such as dendritic cells (DCs), T, B, and natural killer (NK) cells. The immune response, as most biological processes in the female reproductive tract (FRT), is mainly regulated by estrogen and progesterone and their (immune cells) responses vary during different physiological phases of reproduction, such as menstrual cycle, pregnancy, and post menopause. …”
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A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action by Ken-ichiro Minato, Akihiro Ohara, Masashi Mizuno

“…Our results suggested that the PCPS could induce proinflammatory action in the immune response. In addition, the proinflammatory effect of the PCPS on THP-1 was enhanced by 5′-GMP-Na, while it was reduced by vitamin D2. …”
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Immune Privilege and Eye-Derived T-Regulatory Cells by Hiroshi Keino, Shintaro Horie, Sunao Sugita

“…The eye and immune system use strategies to maintain the ocular immune privilege by regulating the innate and adaptive immune response, which includes immunological ignorance, peripheral tolerance to eye-derived antigens, and intraocular immunosuppressive microenvironment. …”
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Mechanisms of Action of Mesenchymal Stem Cells in Metabolic-Associated Fatty Liver Disease by Sitong Yi, Qingwei Cong, Ying Zhu, Qiumin Xu

“…They can also reduce liver tissue injury and reverse the development of MAFLD by regulating immune response, antifibrotic activities, and lipid metabolism. …”
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Activation of Macrophages by Oligomeric Proteins of Different Size and Origin by Indrė Dalgėdienė, Asta Lučiūnaitė, Aurelija Žvirblienė

“…Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host’s proteins. …”
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Sigma Virus (DMelSV) Incidence in Lines of Drosophila melanogaster Selected for Survival following Infection with Bacillus cereus by Meghan L. Bentz, Eve A. Humphrey, Lawrence G. Harshman, Marta L. Wayne

“…The immune response of Drosophila melanogaster is complex and involves both specific and general responses to parasites. …”
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Resolvin D1 Reduces the Immunoinflammatory Response of the Rat Eye following Uveitis by Rossi Settimio, Di Filippo Clara, Ferraraccio Franca, Simonelli Francesca, D'Amico Michele

“…This study investigated whether the administration of resolvin D1 to rats with endotoxininduced uveitis (EIU) ameliorates the immuno-inflammatory profile of the eye. 24 h after the administration of 200 μg LPS into the footpad of Sprague-Dawley rats, severe changes of the structure of the eye occurred concomitantly with a severe inflammatory and immune response. These latter included strong infiltration of PMN leukocytes CD11b+ T-lymphocytes CD4+ and CD8+ within the eye and a significant release of the cytokines/chemokines TNF-alpha, CXCL8, and RANTES too. …”
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Vitamin D Potentiates the Inhibitory Effect of MicroRNA-130a in Hepatitis C Virus Replication Independent of Type I Interferon Signaling Pathway by Xiaoqiong Duan, Yujuan Guan, Yujia Li, Shan Chen, Shilin Li, Limin Chen

“…Our previous study established that miR-130a inhibits HCV replication by restoring the host innate immune response. We aimed to determine whether there is additive inhibitory effect of calcitriol and miR-130a on HCV replication. …”
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The Role of PPARs in Placental Immunology: A Systematic Review of the Literature by Stefan Hutter, Julia Knabl, Ulrich Andergassen, Udo Jeschke

“…They are expressed in most human organs and their function extends from regulating metabolism, homeostasis, and carcinogenesis to immune response. In the recent years, PPARs have been identified in most reproductive tissues and in all lines of immune cells. …”
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Lipid metabolism in myeloid cell function and chronic inflammatory diseases by Ayaka Ito, Ayaka Ito, Ayaka Ito, Takayoshi Suganami, Takayoshi Suganami, Takayoshi Suganami, Takayoshi Suganami

“…Immune cells adapt their metabolism in response to their differentiation and activation status to meet the energy demands for an appropriate immune response. Recent studies have elucidated that during immune cell metabolic reprogramming, lipid metabolism, including lipid uptake, de novo lipid synthesis and fatty acid oxidation, undergoes significant alteration, resulting in dynamic changes in the quantity and quality of intracellular lipids. …”
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Prevention and treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage by Kyle McGrath, Grace Hey, Ghaidaa Ebrahim, Noah Gilberstadt, David Mahan, Brandon Lucke-Wold

“…Numerous preclinical investigations highlight novel targets related to the immune response that could prove effective at improving outcomes in clinical trials. …”
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