Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy. by Xin-Zhuan Su, Fangzheng Xu, Rachel V Stadler, Awet Alem Teklemichael, Jian Wu

“…This assay reviews the factors affecting the disease severity, the genetics of host-parasite interaction, immune evasion mechanisms, and approaches potentially to improve host immune response for vaccine development.…”
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Manipulation of Type I Interferon Signaling by HIV and AIDS-Associated Viruses by Buyuan He, James T. Tran, David Jesse Sanchez

“…Overall, a better understanding of these mechanisms creates avenues to better understand the innate immune response to these viruses as well as plan the development of antivirals that would allow the natural antiviral effect of Type I Interferons to manifest during these infections.…”
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Long-Term Survival and PSA Control with Radiation and Immunotherapy for Node Positive Prostate Cancer by M. Kamrava, Kwong Y. Tsang, R. A. Madan, A. Kaushal, C. N. Coleman, J. Gulley

“…ELISPOT immunoassay studies demonstrated PSA specific T-cells prior to starting vaccine therapy suggesting that this positive response may be related to an improved antitumor immune response of the patient, increased immunogenicity of the tumor, or decreased activation of immune escape pathways. …”
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Potential Use of Bisphosphonates in Invasive Extramammary Paget’s Disease: An Immunohistochemical Investigation by Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Setsuya Aiba

“…Among them, the abrogation of immunosuppressive cells, myeloid derived suppressor cells (MDSC), by BPs might be one of the optimal methods to induce an antitumor immune response both locally and at sites remote from the tumor. …”
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Listeria Rhombencephalitis Complicating Anti-TNF Treatment during an Acute Flare of Crohn’s Colitis by L. Stratton, G. R. Caddy

“…These suppress the immune response, and the patient is more susceptible to infection. …”
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Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation by Asiel Arce-Sillas, Diana Denisse Álvarez-Luquín, Beatriz Tamaya-Domínguez, Sandra Gomez-Fuentes, Abel Trejo-García, Marlene Melo-Salas, Graciela Cárdenas, Juan Rodríguez-Ramírez, Laura Adalid-Peralta

“…T regulatory cells play a key role in the control of the immune response, both in health and during illness. While the mechanisms through which T regulatory cells exert their function have been extensively described, their molecular effects on effector cells have received little attention. …”
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Nutrition and Helicobacter pylori: Host Diet and Nutritional Immunity Influence Bacterial Virulence and Disease Outcome by Kathryn P. Haley, Jennifer A. Gaddy

“…In this review we will discuss how H. pylori is able to create a replicative niche within the hostile host environment by subverting and modifying the host-generated immune response as well as successfully competing for limited nutrients such as transition metals by deploying an arsenal of metal acquisition proteins and virulence factors. …”
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Evaluation and Interpretation of Transcriptome Data Underlying Heterogeneous Chronic Obstructive Pulmonary Disease by Seokjin Ham, Yeon-Mok Oh, Tae-Young Roh

“…Differentially expressed or co-expressed genes in the protein interaction subnetworks were linked with mitochondrial dysfunction and the immune response, as expected. Computational protein localization prediction revealed that 19 proteins showing changes in subcellular localization were mostly related to mitochondria, suggesting that mislocalization of mitochondria-targeting proteins plays an important role in COPD pathology. …”
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Small-Animal X-ray Dose from Micro-CT by John M. Boone, Orlando Velazquez, Simon R. Cherry

“…Although the radiation levels used for micro-CT are generally not lethal to the animal, they are high enough where changes in the immune response and other biological pathways may alter the experimental outcomes. …”
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Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature by Carlos Zagalo, Francesca Pierdomenico, José Cabeçadas, Pedro David Santos

“…Pregnancy and tumorogenesis share some important events such as immunologic tolerance, angiogenesis, and editing the host immune response. Little is known about the relationship between these events in pregnancy and in tumorogenesis.…”
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Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine by Vijay Kumar

“…On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
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Potential of Eurycoma longifolia, Curcuma zedoaria, and Allium sativum extracts as phytobiotics for shrimp health by Mohamad Iqbal Kurniawinata, Sukenda Sukenda, Dinamella Wahjuningrum, Widanarni Widanarni, Julie Ekasari

“… This study evaluated the efficacy of Eurycoma longifolia, Curcuma zedoaria, and Allium sativum in improving the immune response and resistance of whiteleg shrimp to prevent Vibrio parahaemolyticus infection. …”
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Leishmania mexicana: Novel Insights of Immune Modulation through Amastigote Exosomes by Laura Enedina Soto-Serna, Mariana Diupotex, Jaime Zamora-Chimal, Adriana Ruiz-Remigio, José Delgado-Domínguez, Rocely Buenaventura Cervantes-Sarabia, Adriana Méndez-Bernal, Alma Reyna Escalona-Montaño, María Magdalena Aguirre-García, Ingeborg Becker

“…The exosomes from Leishmania parasites contain an array of parasite molecules such as virulence factors and survival messengers, capable of modulating the host immune response and thereby favoring the infection of the host. …”
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Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

“…The secondary and translational endpoints are adverse events and the immune response directed against cancer following PITHAC. …”
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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3 by Ling Ye, Shengqi Shen, Qiankun Mao, Hui Lu, Haiying Liu, Pinggen Zhang, Zetan Jiang, Wenhao Ma, Yuchen Sun, Yiyang Chu, Zilong Zhou, Rui Liu, Jian Li, Shi-ting Li, Ping Gao, Huafeng Zhang

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Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy by Patrick Hwu, Ravi Murthy, Aung Naing, Sapna P. Patel, Simon Young, Alda Tam, Nina M. Muñoz, Malea Williams, Katherine Dixon, Crystal Dupuis, Amanda McWatters, Rony Avritscher, Soraya Zorro Manrique, Kevin McHugh, David Leach, Jeffrey D. Hartgerink, Punit Prakash, Rahul A. Sheth

“…The influence of varying needle design and hydrogel-based drug delivery on the immune response to a stimulator of interferon genes (STING) agonist was evaluated using flow cytometry and single cell RNA sequencing. …”
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Tertiary Lymphoid Structure in Dental Pulp: The Role in Combating Bacterial Infections by Ruiqi Li, Fan Gu, Linlin Peng, Tingting Huan, Zhuo Zhou, Yaling Song, Jinmei He, Kaili Ye, Yao Sun, Tiejun Li, Miao He, Zhuan Bian, Wei Yin

“…However, the role of TLS in immune response and the molecules that drive its formation remain uncertain. …”
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Integrating proteomics and metabolomics to elucidate the regulatory mechanisms of pimpled egg production in chickens by Wenqiang Li, Xueying Ma, Xiaomin Li, Xuguang Zhang, Yifei Sun, Chao Ning, Qin Zhang, Dan Wang, Hui Tang

“…Enrichment analysis revealed that the DEPs were enriched in pathways related to ion transport, energy metabolism, and immune responses. The study found that in the normal eggs (NE) group, HCO₃⁻ was predominantly transported via SLC4A1, although other transport pathways may also play a role. …”
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Beta-adrenergic blocking agents in cutaneous and oral melanoma by Sivakamavalli Jeyachandran

“…Beta-adrenergic receptors, present on various cell types including tumor cells, influence cancer processes like cell proliferation, angiogenesis, metastasis, and immune response modulation. In melanoma, beta-blockers may alter the tumor microenvironment, affecting cancer progression and treatment outcomes. …”
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Use of Autoantibodies to Detect the Onset of Breast Cancer by Jérôme Lacombe, Alain Mangé, Jérôme Solassol

“…Identification of tumor-specific markers capable of eliciting an immune response in the early stages of tumor development seems to provide an effective approach for early diagnosis. …”
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