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  1. 841

    Lipopeptide adjuvants for antibiotics and vaccines: the future step in the fight against multidrug-resistant and extensively drug-resistant pathogens by Chloé O. Sebilleau, Steven J. Sucheck

    Published 2024-04-01
    “…In the case of vaccines, they allow for modulation and increase of the immune response. Lipopeptides are molecules of choice because of their ability to activate specific cell surface receptors, penetrate the outer membrane of GNB, safety and ease of synthesis. …”
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    Article
  2. 842

    Genetic Risk Factors of Systemic Lupus Erythematosus in the Malaysian Population: A Minireview by Hwa Chia Chai, Maude Elvira Phipps, Kek Heng Chua

    Published 2012-01-01
    “…SLE is characterized by deficiency of body's immune response that leads to production of autoantibodies and failure of immune complex clearance. …”
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    Article
  3. 843

    Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity. by Quanhui Dai, Kristina Preusse, Danni Yu, Rhett A Kovall, Konrad Thorner, Xinhua Lin, Raphael Kopan

    Published 2024-12-01
    “…Transcriptomic analysis of colonic spheroids uncovered no evidence of dimer-dependent target gene miss-regulation, confirmed impaired stem cell maintenance in-vitro, and discovered an elevated signature of epithelial innate immune response to symbionts, a likely underlying cause for heightened sensitivity in NDD mice. …”
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    Article
  4. 844

    Actinomycotic osteonecrosis of the maxilla as a post-covid sequelae: A case report by V Vasanthi, Selvakumar Thulasiraman, Rajkumar Krishnan, Annasamy Ramesh Kumar

    Published 2024-03-01
    “…The dysregulated immune response from COVID-19 infection predisposes patients to opportunistic infections. …”
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    Article
  5. 845

    Viruses Seen by Our Cells: The Role of Viral RNA Sensors by Elias A. Said, Nicolas Tremblay, Mohammed S. Al-Balushi, Ali A. Al-Jabri, Daniel Lamarre

    Published 2018-01-01
    “…The role of the innate immune response in detecting RNA viruses is crucial for the establishment of proper inflammatory and antiviral responses. …”
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    Article
  6. 846

    Imaging of CD47 Expression in Xenograft and Allograft Tumor Models by Alexander Zheleznyak, Oluwatayo F. Ikotun, Julie Dimitry, William A. Frazier, Suzanne E. Lapi

    Published 2013-11-01
    “…CD47 has been shown to be overexpressed by various tumor types as a means of escaping the antitumor immune response. The goal of this research was to investigate the utility of CD47 imaging using positron emission tomography (PET) in both human xenograft and murine allograft tumor models. …”
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    Article
  7. 847

    Advances in Immunotherapy and Targeted Therapy of Malignant Melanoma by Xue Wang, Shanshan Ma, Shuting Zhu, Liucun Zhu, Wenna Guo

    Published 2025-01-01
    “…However, the heterogeneity of tumor immune response causes more than half of patients to not benefit from clinical immunotherapy and targeted therapy, which delays the patient’s condition and causes them to suffer adverse immune events’ side effects. …”
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    Article
  8. 848

    Hemizygous Moesin (MSN) Gene Deletion in an Adult With Chronic Neutropenia by Yandy Marx Castillo-Aleman, Francisco Sotomayor-Lugo, Sherjeel Sana, Nameer Abdul Raheem Kadhum Al-Saadawi, Yendry Ventura-Carmenate, David Dennison, Gianina Statache, Julieta Osorio-Zuluaga, Ahmad Raza, David Grossman

    Published 2024-01-01
    “…It is characterized by cytopenias, hypogammaglobulinemia, poor immune response to vaccine antigens, and increased susceptibility to early-life infections. …”
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    Article
  9. 849

    A mathematical model for within-host Toxoplasma gondii invasion dynamics by Adam Sullivan, Folashade Agusto, Sharon Bewick, Chunlei Su, Suzanne Lenhart, Xiaopeng Zhao

    Published 2012-06-01
    “…The model considers theinvasion process, egress kinetics, interconversion between fast-replicatingtachyzoite stage and slowly replicating bradyzoite stage, as well as thehost's immune response. Analytical and numerical studies of the model can helpto understand the influences of various parameters to the transient andsteady-state dynamics of the disease infection.…”
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  10. 850

    Comparison of Effects of Smoking and Smokeless Tobacco “Maras Powder” Use on Humoral Immune System Parameters by Murat Aral, Hasan Cetin Ekerbicer, Mustafa Celik, Pınar Ciragil, Mustafa Gul

    Published 2006-01-01
    “…Effects of Maras powder on humoral immune response were found to be similar to that of smoking.…”
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    Article
  11. 851

    Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis by Yujie Xiao, Yixuan Yuan, Dahai Hu, Hongtao Wang

    Published 2024-01-01
    “…This review comprehensively explores the biology of exosome-derived miRNAs, which originate from both immune cells (such as macrophages and dendritic cells) and nonimmune cells (such as endothelial and epithelial cells) and play a dynamic role in modulating pathways that affect the course of sepsis, including those related to inflammation, immune response, cell survival, and apoptosis. Taking into account these dynamic changes, we further discuss the potential of exosome-derived miRNAs as biomarkers for the early detection and prognosis of sepsis and advantages over traditional biomarkers due to their stability and specificity. …”
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  12. 852

    Immunogenetic Factors Associated with Severe Respiratory Illness Caused by Zoonotic H1N1 and H5N1 Influenza Viruses by Jennifer Juno, Keith R. Fowke, Yoav Keynan

    Published 2012-01-01
    “…By better defining the role of genetic variability in influenza infection and identifying key polymorphisms that impair the host immune response or correlate with protection, we will be able to better identify at-risk populations and new targets for therapeutic interventions and vaccines. …”
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    Article
  13. 853

    A mathematical model for M-phase specific chemotherapy including the $G_0$-phase and immunoresponse by Wenxiang Liu, Thomas Hillen, H. I. Freedman

    Published 2007-01-01
    “…In this paper we use a mathematical model to study the effect ofan $M$-phase specific drug on the development of cancer, includingthe resting phase $G_0$ and the immune response. The cell cycle ofcancer cells is split into the mitotic phase (M-phase), thequiescent phase ($G_0$-phase) and the interphase ($G_1,\ S,\G_2$ phases). …”
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  14. 854

    BK Polyomavirus and acute kidney injury in transplant recipients: signaling pathways and molecular mechanisms by Samar Bizhani, Afsoon Afshari, Ramin Yaghobi

    Published 2025-01-01
    “…Although reactivation is often asymptomatic, it can present as AKI, which is a risk factor for early loss of the transplanted organ. The immune response to BKPyV is crucial in controlling the virus and safeguarding organs from damage during infection. …”
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    Article
  15. 855

    The dynamics of CD4+ T cell proliferation and regulation by Mingran Zhang, Junling Ma, Roderick Edwards, Meili Li

    Published 2025-12-01
    “…We use mathematical modeling to study the proliferation dynamics of CD4+ T cells within an immune response. This proliferation is driven by the autocrine reaction of helper T cells and interleukin-2 (IL-2), and regulated by natural regulatory T cells (nTregs). …”
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  16. 856

    Bacteriophages: Uncharacterized and Dynamic Regulators of the Immune System by Anshul Sinha, Corinne F. Maurice

    Published 2019-01-01
    “…Here, we aim to fill this gap by providing an overview of bacteriophage communities in the gut during human development, detailing recent findings for their bacterial-mediated effects on the immune response and summarizing the latest evidence for direct interactions between them and the immune system. …”
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    Article
  17. 857

    Role of the Microenvironment in Mesenchymal Stem Cell-Based Strategies for Treating Human Liver Diseases by Shan-jing Xu, Li-ping Ye, Wei Wang, Ya-hong Chen, Jian Dong, Xin-li Mao, Shao-wei Li

    Published 2021-01-01
    “…We, therefore, summarized the mechanisms underlying the MSC immune response, especially the interaction between MSCs and the liver microenvironment, discussing how to achieve better therapeutic effects.…”
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  18. 858

    AhR governs lipid metabolism: the role of gut microbiota by Wanru Zheng, Mengkuan Liu, Xinyu Lv, Cuimei He, Jie Yin, Jie Ma

    Published 2025-01-01
    “…Under physiological conditions, AhR mainly participates in regulating the body’s immune response, cell proliferation, and apoptosis among a series of processes. …”
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  19. 859

    Stability Analysis and Clinic Phenomenon Simulation of a Fractional-Order HBV Infection Model by Yongmei Su, Sinuo Liu, Shurui Song, Xiaoke Li, Yongan Ye

    Published 2020-01-01
    “…The basic reproductive number R0 and the cytotoxic T lymphocytes’ immune-response reproductive number R1 were derived. There were three equilibrium points of the model, and stable analysis of each equilibrium point was given with corresponding hypothesis about R0 or R1. …”
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    Article
  20. 860

    Glioblastoma Multiforme Stem Cells by Irena Dimov, Deasanka Tasic-Dimov, Irena Conic, Vladisav Stefanovic

    Published 2011-01-01
    “…The endogenous immune regulation is likely to limit or abrogate the efficacy of the host's immune response, as well as the developed immunotherapeutic strategies at present. …”
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