A 3D Clinical Face Phenotype Space of Genetic Syndromes Using a Triplet-Based Singular Geometric Autoencoder by Soha S. Mahdi, Eduarda Caldeira, Harold Matthews, Michiel Vanneste, Nele Nauwelaers, Meng Yuan, Giorgos Bouritsas, Gareth S. Baynam, Peter Hammond, Richard Spritz, Ophir D. Klein, Michael Bronstein, Benedikt Hallgrimsson, Hilde Peeters, Peter Claes

“…Experiments are designed to illustrate the following properties of CFPSs that can aid clinicians in narrowing down their search space: a CFPS can 1) classify syndromes accurately, 2) generalize to novel syndromes, and 3) preserve the relatedness of genetic diseases, meaning that clusters of phenotypically similar disorders reflect functional relationships between genes. …”
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Housing insecurity pathways to physiological and epigenetic manifestations of health among aging adults: a conceptual model by Aarti C. Bhat, Aarti C. Bhat, Aarti C. Bhat, Andrew Fenelon, Andrew Fenelon, Andrew Fenelon, David M. Almeida, David M. Almeida, David M. Almeida

“…This review adapts existing stress process models to propose a conceptual model illustrating potential pathways linking the specific stressor of housing insecurity to physiological and epigenetic manifestations of stress among aging adults.MethodsThis narrative review examines literature across multiple fields, including public health, psychology, and sociology. …”
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Validation of the efficacy of the porous medium model in hemodynamic analysis of iliac vein compression syndrome by Lingling Wei, Ke Hu, Jiaqiu Wang, Shuang Zhang, Xiaoxiao Yang, Yuanli Chen, Chenshu Li, Xinwu Lu, Kaichuang Ye, Peng Qiu, Yanqing Zhan, Yanqing Zhan

“…Pre-operative Computed Tomography (CT) scan images of patients with IVCS were utilized to reconstruct models illustrating both the compression and collateral circulation of the iliac vein. …”
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Compound weather and climate extremes in the Asian region: science-informed recommendations for policy by R. Krishnan, Chirag Dhara, Takeshi Horinouchi, C. Kendra Gotangco Gonzales, C. Kendra Gotangco Gonzales, A. P. Dimri, A. P. Dimri, M. Singh Shrestha, P. Swapna, M. K. Roxy, Seok-Woo Son, Seok-Woo Son, D. C. Ayantika, Faye Abigail T. Cruz, Fangli Qiao

“…This paper analyzes three typologies of compound events in the Asian region, illustrating their regional complexity and potential linkages to climate change. …”
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Prognostic correlation analysis of multiple myeloma based on HALP score of peripheral blood before chemotherapy by CHEN Min, AN Liying, LIN Xiaojing, ZHAO Pan, ZOU Xingli, WEI Jin, NI Xun

“…Univariate and multivariate analyses were conducted using the Cox regression model, and a forest plot was generated using Graphpad Prism to illustrate factors that may impact patient prognosis. …”
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AI-optimized electrochemical aptasensors for stable, reproducible detection of neurodegenerative diseases, cancer, and coronavirus by Amira Elsir Tayfour Ahmed, Th.S. Dhahi, Tahani A. Attia, Fawzia Awad Elhassan Ali, Mohamed Elshaikh Elobaid, Tijjani Adam, Subash C.B. Gopinath

“…The performance metrics outlined in the comparative table illustrate the significant advancements enabled by AI integration. …”
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Nonhomogeneous Markov chains for degeneration behaviour of RC members’ durability and its Bayesian updating by Ruiqi Guo, Dengguo Li, Guoxin Chen, Yu Jin, Hui Li, Yuanpeng Zhang

“…Manuscript uses a simulated case study and a real case study to illustrate the application process of the proposed method and to examine the predictive performance of the model. …”
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Brodifacoum causes coagulopathy, hemorrhages, and mortality in rainbow trout (Oncorhynchus mykiss) at environmentally relevant hepatic residue concentrations by Hannah Schmieg, Hermann Ferling, Karina Annika Bucher, Stefanie Jacob, Julia Regnery, Hannah Schrader, Julia Schwaiger, Anton Friesen

“…The lowest hepatic brodifacoum concentration associated with effects in trout was on average 122.6 ng/g liver wet weight, which is in the range of previously reported brodifacoum residues in wild fish. These findings illustrate the risks associated with the use of anticoagulant rodenticides for freshwater fish and reinforce the need to stipulate all available and appropriate risk mitigation measures to prevent emissions at source.…”
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ICRF resonance cones in the low-density scrape-off-layer of ASDEX Upgrade by Felix Paulus, Volodymyr Bobkov, Helmut Faugel, Helmut Fünfgelder, Oleksii Girka, Gustavo Grenfell, Roman Ochoukov, Wouter Tierens, Hartmut Zohm, the ASDEX Upgrade Team

“…In the context of experiments at ASDEX Upgrade, simulations illustrate that the RCs can emerge from a single tile of the ICRF antenna limiter. …”
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Threshold responses of freshwater fish community size spectra to invasive species by Bradley Novak, Brent A. Murry, Jeff S. Wesner, Vojsava Gjoni, Caroline C. Arantes, Erin Shepta, Justin P. F. Pomeranz, James R. Junker, Kathrine Zipfel, Andrew Stump, Levi E. Solomon, Kristopher A. Maxson, Jason A. DeBoer

“…Our study demonstrates a clear shift in fish community size structure following invasion by Silver Carp and suggests that pre‐invasion CSS slopes may serve as a restoration target. It also illustrates the benefits of CSS to guide Silver Carp and other AIS management.…”
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State Estimation in Power Systems Under False Data Injection Attack Using Total Least Squares by Bamrung Tausiesakul, Krissada Asavaskulkiet, Chuttchaval Jeraputra, Ittiphong Leevongwat, Thamvarit Singhavilai, Supun Tiptipakorn

“…To demonstrate the usability of the proposed algorithms and to illustrate their performance, numerical simulation is conducted taking into account two IEEE power system standards, such as IEEE 9-bus and 14-bus models. …”
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MicroRNA-26b inhibits cardiac remodeling after myocardial infarction by targeting ring finger protein 6 expression by Chun-Mei Tang, Qiang Su, Hai-Xia Zhao, He-Huan Sui, Jing Liang, Li-Sha Zhu, Si-Yun Yang, Tao Liu

“…Additionally, an in vitro cell model illustrated that miR-26b upregulation could increase cell viability and reduce apoptosis, whereas RNF6 overexpression reversed its effect. …”
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Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways by Jing Huang, Lei Li, Liyan Xu, Lixin Feng, Yuxin Wang, Attila Gabor SIK, Meng Jin, Rongchun Wang, Kechun Liu, Xiaobin Li

“…Inflammatory bowel disease (IBD) is characterized by uncontrolled, chronic relapsing inflammation in the gastrointestinal tract and has become a global healthcare problem. Here, we aimed to illustrate the anti-inflammatory activity and the underlying mechanism of methyl 3-bromo-4,5-dihydroxybenzoate (MBD), a compound derived from marine organisms, especially in IBD, using a zebrafish model. …”
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Maternal exposure to fine particulate matter before and during pregnancy, and the risk of birth defects: A population-based study by Shihan Zhen, Na Li, Yan Li, Qian Li, Lu Zheng, Zhouxin Yin, Yan Dou, Shuqi Wu, Yilin Liu, Xiaoyan Zhang, Xinyue Yang, Ye Wang, Wenxiu Ge, Xiaoyu Gao, Jing Yang, Fengchao Liang, Jiajin Hu, Ying Zhao

“…Mothers exposed to elevated levels of PM2.5 during both the preconception period and pregnancy exhibited the highest risk of total birth defects (odds ratio: 4.43, 95% CI: 4.17, 4.71). Our findings illustrated that maternal exposure to PM2.5 before and during pregnancy was associated with increased risks of birth defects and underscored the potential health benefits of reducing air pollution exposure during the preconception period and pregnancy.…”
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Diagnostic Management and Surgical Treatment of Isolated Tricuspid Regurgitation by Arthur Cicupira Rodrigues de Assis, Gustavo Andre Boeing Boros, Lea Maria Macruz Ferreira Demarchi, Thiago Luis Scudeler, Paulo Cury Rezende

“…No signs of infection or vegetation nor disruption of strands were observed. This report illustrates a very rare case of symptomatic primary isolated severe tricuspid regurgitation caused by myxomatous degeneration of the leaflets. …”
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Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation by Lin Cheng, Sheng Xu, Yu‐feng Wang, Sheng‐wei Li, Bin Li, Xiao‐Guang Li

“…Whether plasma ctDNA detection can predict its efficacy should be illustrated. Methods We recruited 43 patients with inoperative stage I NSCLC, all of whom underwent biopsy‐synchronous microwave ablation (MWA). …”
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Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study by Gang Wei, Cheng Zhang, Feng-Jie Shen, Hua-Qi Guo, Lin Liu

“…Rs7575840 in 6.5kda upstream of ApoB gene, rs11591147 in PCSK9 gene and rs9644862 in the CDKN2B-AS1 (or named ANRIL; p15AS; PCAT12; CDKN2BAS; CDKN2B-AS; NCRNA00089) gene were illustrated to mostly influence the risk of intestinal vascular diseases. …”
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Bridging incremental to transformative hazard management strategies on the Tule River Indian Reservation by Natalie Herbert, Caroline Beckman, Kerri Vera, Eric Coles, Thomas Kim, Seung-Hyun Cho, Gabrielle Wong-Parodi

“…Second, our conceptual framework illustrates the incremental-transformative adaptation tension. …”
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Cochlear implantation in vestibular schwannoma: A game changer? A narrative review by Luis Lassaletta, Miryam Calvino, Isabel Sánchez-Cuadrado, José Manuel Morales-Puebla, Javier Gavilán

“…Articles written in English on VS and cochlear implantation were eligible for inclusion. Pictures of illustrative cases from a tertiary center were included. …”
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Social context affects tissue-specific copper distribution and behaviour of threespine stickleback (Gasterosteus aculeatus) by Sienna L. Overduin, Shaun S. Killen, Alex M. Zimmer, Jenelle D. McCuaig, Lucy Cotgrove, Isabel Aragao, Kelly J. Rozanitis, Kurt O. Konhauser, Daniel S. Alessi, Tamzin A. Blewett

“…However, this Cu distribution was also present within the control fish, which had not been exposed to Cu, suggesting that the social context affects endogenous Cu distribution under stressful conditions. Our results illustrate the differences in physiology and behaviour that can arise when social contexts are manipulated and stress the importance of considering sociality when conducting toxicity tests with social organisms.…”
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