Antitumor Effect of Demethylzeylasteral (T-96) on Triple-Negative Breast Cancer via LSD1-Mediate Epigenetic Mechanisms by Zhengjie Shen, Yongjuan Gu, Ruiyang Jiang, Heya Qian, Siyuan Li, Lixian Xu, Wenzhe Gu, Yun Zuo

“…Conclusions & Implications. The results illustrated that T-96 exerted antitumor activity in highly metastatic TNBC by inactivating the LSD1 function.…”
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Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice by Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang

“…Schematic diagram of monocyte TREM-1-mediated dopaminergic neuron damage. The figure illustrates that in experimental MPTP-induced PD model mice, the number of inflammatory monocytes in the peripheral blood increases, after which the monocytes infiltrate the CNS through the Blood-Brain Barrier(BBB). …”
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A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: Application to a dose-finding trial for a novel Russell's viper antivenom in Myanmar. by James A Watson, Thomas Lamb, Jane Holmes, David A Warrell, Khin Thida Thwin, Zaw Lynn Aung, Min Zaw Oo, Myat Thet Nwe, Frank Smithuis, Elizabeth A Ashley

“…We propose a model based, Bayesian phase 2 type, adaptive clinical trial design for the characterisation of optimal initial antivenom doses in contexts where both efficacy and toxicity are measured as binary endpoints. This design is illustrated in the context of dose-finding for Daboia siamensis (Eastern Russell's viper) envenoming in Myanmar. …”
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BRAIN CHANGER. Felice Jacka, 321 pages, Macmillan, 2019 (ISBN: 978-1-76055-651-8) by Cécil J.W. Meulenberg

“…Consecutive chapters illustrate recent understandings of the effects of diets on the immune system, their influence on brain plasticity (which also occurs in older humans), epigenetics, food sensitivities, inflammation, and centrally, the importance of food to the gut microbiota (including the consumption of fermented foods). …”
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A surge in female condom distribution during the COVID-19 pandemic in Gauteng province, South Africa by Cyril Bernsah Fonka, Nicola Christofides

“…Analysis in MS Excel 2016 illustrates the changes in the patterns and the trend in female condom distribution over the study period. …”
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A scoping review on the psychosocial interventions used in day care service for people living with dementia. by Dympna Tuohy, Liz Kingston, Eileen Carey, Margaret Graham, Liz Dore, Owen Doody

“…<h4>Conclusions</h4>This review has illustrated the wide variety in the types, range and facilitation of psychosocial interventions within adult day care services. …”
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The effects of meteorological drought on oak forest dieback in Ilam province by shamsallah Asgari, tayeb razi, Mohamadreza Jafari, Ali Akbar noroozi

“…The results demonstrate a correlation coefficient of 96.6% and an explanation coefficient of R2 = 0.985 for the 2002-2006 time series, a correlation coefficient of 95.4% and an explanation coefficient of R2 = 0.980 for the 2007-2011 time series, and a correlation coefficient of 98.8% and an explanation coefficient of R2 = 0.995 for the 2012-2016 time series. These findings illustrate the influence of drought and its variations in terms of intensity and duration on oak forests in the Zagros region of Ilam. …”
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Nutrient conditions affect antimicrobial pharmacodynamics in Pseudomonas aeruginosa by Maik Kok, Thomas Hankemeier, J. G. Coen van Hasselt

“…Using pharmacokinetic-pharmacodynamic simulations, we illustrate that the magnitude of the nutrient-driven pharmacodynamic changes impact treatment for clinical dosing strategies of tobramycin. …”
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La gestion paradoxale des ripisylves des cours d’eau de piedmont alpin endigués by André Evette, Caroline Zanetti, Paul Cavaillé, Fanny Dommanget, Patrice Mériaux, Michel Vennetier

“…Des expérimentations menées dans le cadre du Projet Interreg Géni’Alp en piedmont alpin ont permis d’affiner les connaissances à la fois sur les risques induits par les systèmes racinaires des ligneux dans les digues et sur l’impact de l’artificialisation des bords de cours d’eau sur la biodiversité.Cet article a pour objectif d’illustrer ce paradoxe à la lueur des résultats de ces expérimentations. …”
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Le motif de la sorcière : des usages de l’anachronisme dans le Premier Faust de Goethe by Françoise Knopper

“…Ce motif de la sorcière est aussi utilisé à titre de symbole dans la construction de la connaissance : les sorcières accompagnent Faust dans son exploration de l’univers et mani­festent la relation au feu, à l’air, au monde souterrain. « L’élément sorcière » se caractérise par une mobilité qui reproduit l’énergie vitale, l’alternance de mécanismes d’attirance et de répulsion, illustrant l’intérêt porté par Goethe au magnétisme et à l’électricité. …”
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Pengembangan Laboratorium Virtual Berbasis Website di Kelas X Teknik Komputer dan Jaringan (TKJ) by Dara Riska, Afrizal Mayub, Rosane Medriati

“…That percentage was average from format aspect = 85,41% with criteria very appropriate; illustration aspect = 86,1% with criteria very appropriate; language aspect = 85,41% with criteria very appropriate; and content aspect = 91,67% with criteria very appropriate. …”
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A COMBINATION TECHNIQUE OF AUTOLOGOUS AUGMENTATION AND BREAST LIFTING IN HYPOPLASTIC-THIRD GRADE PTOTIC BREAST: A CASE REPORT by Beta Subakti Nataatmadja, Nida' Fahima Amatullah, Loelita Marcelia Lumintang

“…This case report highlights the relevance of the chosen augmentation method in addressing ptosis. Case Illustration: A 30-year-old woman had breast ptosis after her 2nd child and wanted a breast lift to have lifted and firmer breasts. …”
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Genome-wide identification, characterization and expression pattern analysis of HAK/KUP/KT potassium transporter gene family in potato by Kun Liu, Yonglin Qin, Lan Wu, Rong Yi, Xiaohua Shi, Jing Yu, Xiaohong Shi, Wenzhuo Dong, Liguo Jia, Mingshou Fan

“…To provide a clear and convenient view of StHAK gene expression across different tissues in potato, we generated a cartoon heatmap to vividly illustrate the tissue-specific expression of StHAK genes, which is unprecedented in the gene family analysis of potato. …”
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Exploring optimal control strategies in a nonlinear fractional bi-susceptible model for Covid-19 dynamics using Atangana-Baleanu derivative by Azhar Iqbal Kashif Butt, Waheed Ahmad, Hafiz Ghulam Rabbani, Muhammad Rafiq, Shehbaz Ahmad, Naeed Ahmad, Saira Malik

“…The effectiveness and efficiency of optimally designed control strategies are showcased through numerical simulations conducted before and after the optimization process. These simulations illustrate the effectiveness of these control strategies in mitigating both financial expenses and infection rates. …”
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SUCCESSFUL PHARYNGOPLASTY AFTER LE FORT I ADVANCEMENT IN A SEVERELY NEGLECTED CLEFT LIP AND PALATE PATIENT by Timotius Hansen Arista, Magda Rosalina Hutagalung

“…Moreover, velopharyngoplasty proceeded with speech therapy yields better recovery. Case Illustration: A seriously neglected case of cleft lip and palate was reported. …”
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Unaccountable counting: the folly of incorporating open ocean carbon sinks in Nationally Determined Contributions by Berger, Manon, Comte, Adrien, Kwiatkowski, Lester, Bopp, Laurent

“…Here, we utilise a high-resolution global ocean biogeochemical model alongside available observations to illustrate why including EEZ carbon sinks in NDCs would be both conceptually and practically highly problematic.To demonstrate this, we focus on the case of the French EEZ, where we simulate an anthropogenic carbon sink of 0.21 GtCO2·yr–1 over the past decade, representing nearly 50% of France’s territorial greenhouse gas emissions over the same period. …”
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Deep learning solutions for inverse problems in advanced biomedical image analysis on disease detection by Amal Alshardan, Hany Mahgoub, Nuha Alruwais, Abdulbasit A. Darem, Wafa Sulaiman Almukadi, Abdullah Mohamed

“…Extensive simulations have been involved to illustrate the better performance of the DLSIP-ABIADD technique. …”
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Sistem Pengontrol Temperatur dan Kelembaban Otomatis untuk Ruang Penyimpanan Buah by Zulkifli Amin, Muhamad Adha

“…However, in order to optimise the results in fruit preservation, the temperature and humidity are also needed to be varied during priod of storage. This article illustrates the development of a system which can automatically control the temperature and humidity of the storage room in accordance with fruit preservation temperature and humidity suggested. …”
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The experience of living with human immunodeficiency virus among adolescents at Felege Hiwot Comprehensive Specialized Hospital Bahir-Dar, Northwest Ethiopia, A phenomenological st... by Bazezew Asfaw Guadie, Minyichil Birhanu Belete, Meseret Mekuriaw Beyene, Ayalew Kassie Melese, Tarik Yenew Tessema, Yinager Workineh

“…To demonstrate findings, the inductive thematic analysis technique was applied using illustrative quotes. Colleague feedback, member checks, and a debriefing were used to guarantee the quality of the data.…”
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THE DEVELOPMENT OF A MOBILE APPLICATION ISMIND FOR FORMATIVE STUDENTS’ ASSESSMENT by Aslina Saad, Fatin Naiemah Khairulanuar, Bahbibi Rahmatullah

“…Adobe Photoshop CS6, Adobe Illustrator CS6, Unity 3D, and Microsoft Visual Studio Code (C#) were utilized in the development process. …”
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