Sustained release of miR-21 carried by mesenchymal stem cell-derived exosomes from GelMA microspheres inhibits ovarian granulosa cell apoptosis in premature ovarian insufficiency by Xiaofei Zhang, Linzi Ma, Xiaotong Liu, Xingyu Zhou, Ao Wang, Yunhui Lai, Jun Zhang, Ying Li, Shiling Chen

“…Conclusion: Our findings illustrate that activating miR-21 through Agomir21-Exo could improve the function of ovarian granulosa cells. …”
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Fuzzy Random Characterization of Pore Structure in Frozen Sandstone: Applying Improved Niche Genetic Algorithm by Yao Ya-feng, Lin Jian, Ge Jian, Peng Shi-long, Yin Jian-chao, Ouyang Li-na

“…Finally, based on the T2 spectrum test of frozen sandstone, the fuzzy random characterization of frozen sandstone pore distribution is carried out by using this transformation method. The results illustrate that the conversion coefficient obtained through the improved algorithm indirectly considers the different surface relaxation rates of different pore sizes and effectively reduces the diffusion coupling effects, and the pore characteristics achieved are more applicable in engineering practices than previous methods.…”
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Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1 by Ziyi Wang, Hao Wang, Xuejiao Chen, Sheng Han, Yulin Zhu, Hanhua Wang, Feng Cheng, Liyong Pu

“…Knocking down ATP6V0D2 impaired the formation of autophagolysosome and aggravated liver IR injury through nonspecific V-ATPase activation independent of V-ATPase-Notchl-Hesl signal axis. In general, we illustrated that the expression of ATP6V0D2 in liver macrophages was upregulated after liver IR, and by gradually promoting the formation of autophagolysosomes to increase autophagy flux to limit the activation of liver inflammation, this regulation is independent of the Notch1-Hes1 signal axis.…”
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Associations of short-term exposure to air pollution with risk of pulmonary space-occupying lesions morbidity based on a time-series study by Xu Zhang, Zijie Pei, Yan Wang, Yaxian Pang, Haiyan Hao, Qingping Liu, Mengqi Wu, Rong Zhang, Helin Zhang

“…Conclusions The present study illustrated risk and burden for pulmonary space-occupying lesions hospitalization associated with air pollution, especially among population aged ≥ 65, or female.…”
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Molecular mechanisms of cis-oxygen bridge neonicotinoids to Apis mellifera Linnaeus chemosensory protein: Surface plasmon resonance, multiple spectroscopy techniques, and molecular... by Xiangshuai Li, Shiyu Li, Yang Liu, Li Cui, Daibin Yang, Shuning Chen, Xusheng Shao, Huizhu Yuan, Xiaojing Yan

“…Molecular docking and dynamics simulations further illustrated the stability of these interactions within the active site of the protein. …”
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A Case of Undiagnosed HIV Infection in a 57-Year-Old Woman with Multiple Myeloma: Consequences on Chemotherapy Efficiency and Safety by I. Poizot-Martin, S. Brégigeon, C. Tamalet, R. Bouabdallah, O. Zaegel-Faucher, V. Obry-Roguet, A. Ivanova, C.E. Cano, C. Solas

“…Conclusion. Our case illustrates the drawback that ignored HIV infection is still causing to cancer patients receiving chemotherapy and highlights the importance of early HIV testing in oncology. …”
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The Treatment Effect of Plantago Major on Lung Cancer Based on the Computed Tomography and Pathological Findings: A Case Report Study by Saade Abdalkareem Jasim, Bashar Mudhaffar Abdullah, Patricio Yánez-Moretta, Wesam R. Kadhum, Yasser Fakri Mustafa, Enas R. Alwaily, Munther Abosoda, Ali Alsalamy, Sada Ghalib Al-Musawi, Alaa A. Omran

“…In addition, the laboratory examinations illustrate that ESR and CRP levels reduced remarkably (from 97 mm/h to 24 mm/h for ESR; from 36.8 mg/L to 1.2 mg/L for CRP) after the treatment. …”
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Green Analytical Method for Simultaneous Determination of Glucosamine and Calcium in Dietary Supplements by Capillary Electrophoresis with Capacitively Coupled Contactless Conducti... by Yen Nhi Do, Thi Lan Phuong Kieu, Thi Huyen My Dang, Quang Huy Nguyen, Thu Hien Dang, Cao Son Tran, Anh Phuong Vu, Thi Trang Do, Thi Ngan Nguyen, Son Luong Dinh, Thi Minh Thu Nguyen, Thi Ngoc Mai Pham, Anh Quoc Hoang, Bach Pham, Thi Anh Huong Nguyen

“…After optimization, the CE conditions for selective determination of glucosamine and Ca2+ were obtained, including a 10 mM tris (hydroxymethyl) aminomethane/acetic acid (Tris/Ace) buffer of pH 5.0 as the background electrolyte; separation voltage of 20 kV; and hydrodynamic injection (siphoning) at 25 cm height for 30 s. The method illustrated good linearity over the concentration range of 5.00 to 200 mg/L of for glucosamine (R2 = 0.9994) and 1.00 to 100 mg/L for Ca2+ (R2 = 0.9994). …”
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A Heterogeneously Integrated 256-Element 5G Phased Array: Design, Assembly, Test by Bodhisatwa Sadhu, Arun Paidimarri, Atom O. Watanabe, Duixian Liu, Xiaoxiong Gu, Christian W. Baks, Yujiro Tojo, Yoshiharu Fujisaku, Isabel De Sousa, Yo Yamaguichi, Ning Guan, Alberto Valdes-Garcia

“…The paper discusses the several challenges and system trade-offs for 5G mmWave phased arrays and illustrates the advantages of heterogeneous integration at the antenna-in-package level. …”
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Crop protection by RNA interference: a review of recent approaches, current state of developments and use as of 2013 by Kirsten Germing, Cecilia Andrea Díaz Navarrete, Andreas Schiermeyer, Udo Hommen, Luise Zühl, Sebastian Eilebrecht, Elke Eilebrecht

“…A horizon scan was conducted with a specific emphasis to identify and illustrate the current state of RNAi developments and applications in crop protection as well as their biomanufacturing readiness levels. …”
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Process variables in mixture experimental design applied to wood plastic composites by Javier Cruz-Salgado, Sergio Alonso-Romero, Edgar Augusto Ruelas-Santoyo, José Alfredo Jiménez-García, Israel Miguel-Andrés, Roxana Zaricell Bautista-López

“…The absence of high multicollinearity, as indicated by variance inflation factor (VIF) values below 5, further supports the model's stability and interpretability. Contour plots illustrate the effect of varying mixture proportions on the response, such as tensile strength, showing a positive impact of both particle size and mixing time. …”
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K-nearest neighbor algorithm for imputing missing longitudinal prenatal alcohol data by Ayesha Sania, Ayesha Sania, Nicolò Pini, Nicolò Pini, Morgan E. Nelson, Michael M. Myers, Michael M. Myers, Lauren C. Shuffrey, Maristella Lucchini, Maristella Lucchini, Amy J. Elliott, Amy J. Elliott, Hein J. Odendaal, William P. Fifer, William P. Fifer

“…AimsThe objective of this study is to illustrate the application of a machine learning algorithm, K Nearest Neighbor (k-NN) to impute missing alcohol data in a prospective study among pregnant women.MethodsWe used data from the Safe Passage study (n = 11,083). …”
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Effect of Modulating Spin-Coating Rate of TiO2 Precursor for Mesoporous Layer on J-V Hysteresis of Solar Cells with Polar CH3NH3PbI3 Perovskite Thin Film by Qi Li, Xiaoping Zou, Yuanyuan Li, Yaxian Pei, Shuangxiong Zeng, Dongdong Guo

“…Firstly, the AFM images illustrate that the polarization behaviors exist and the deformation scale is large at the corresponding position when the DC bias voltage increases. …”
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Alternative splicing for tuneable expression of protein subunits at desired ratios by Christel Aebischer-Gumy, Pierre Moretti, Timothee Brunstein Laplace, Jana Frank, Ysaline Grand, Farid Mosbaoui, Emilie Hily, Anna Galea, Megane Peltret, Carole Estoppey, Daniel Ayoub, Roberto Giovannini, Martin Bertschinger

“…This specific design enables the modulation of the splice ratio by adjusting the strength of the splice acceptor. To illustrate this approach, we developed constructs expressing varying ratios of GFP and dsRED and extended their application to multimeric proteins such as monoclonal antibodies, achieving industrially relevant expression levels (>1 g/L) in a 14-day fed-batch process. …”
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Exome sequencing of UK birth cohorts [version 2; peer review: 2 approved, 1 approved with reservations] by Petr Danecek, Amy Hough, John Wright, Karen Ho, Nicholas J. Timpson, Sarah J. Lindsay, Davide Bonfanti, Daniel S. Malawsky, Rafaq Azad, Deborah Plowman, Sara Widaa, Gemma Shireby, Emla Fitzsimons, David Bann, Matthew E. Hurles, Hilary C. Martin, Susan M. Ring, Dan Mason, Michael A. Quail, Wei Huang, Vivek Iyer, Mahmoud Koko, Iaroslav Popov, Laurie Fabian, Gennadii Zakharov, Ruth Y. Eberhardt, Emma E. Wade, Qin Qin Huang

“…We then present some preliminary analyses to illustrate the quality of the datasets and probe potential sources of bias. …”
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Leveraging ICT to Enable Value Addition and Comprehensive Value Chain Participation for Smallholder Farmers in Kigezi Region: A Case Study of Potato Growers by Byamukama Mpora, Eliab, Sunday,Arthur, Mugalul,George, Turyahebwa,Abanis, Kaaya, Siraj, Turyasingura, Benson, Nakero, Sarah

“…The study of economic development and the well-being of smallholder potato growers in the Kigezi region was illustrated well to the benefit of readers and the magnitude of the outcome. …”
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Designing a Forecasting Model and Evaluating the Strategic Cooperation between the Banking System and Fintech Startups using the Adaptive Neural Fuzzy Inference System (ANFIS) by Arash Onsori, Abbas Khamseh, Taghi Torabi, Hamid Reza Yazdani

“…The initial membership functions, depicted in Figure 1, set the stage for subsequent modeling by illustrating the shape and characteristics of linguistic variables in the ANFIS system. …”
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Construction of the cancer patients’ database based on the US National Health and Nutrition Examination Survey (NHANES) datasets for cancer epidemiology research by Jinyoung Moon, Yongseok Mun

“…To address this gap, the authors developed a cancer patient database from the US NHANES datasets by employing multiple R programming codes. Methods To illustrate the practical application of this methodology to a real-world problem, the authors extracted the R codes applied in an academic paper published in another journal on January 30th, 2024 ( https://doi.org/10.1016/j.heliyon.2024.e24337 ). …”
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Seaweed Fly Larvae Cultivated on Macroalgae Side Streams: A Novel Marine Protein and Omega-3 Source for Rainbow Trout by Niklas Warwas, Emma L. Berdan, Xintian Xie, Elisabeth Jönsson, Jonathan A. C. Roques, Darragh Doyle, Markus Langeland, James Hinchcliffe, Henrik Pavia, Kristina Sundell

“…However, changes in electrogenic intestinal transport were observed between the SWFL and BSFL diets, illustrating the heterogeneous effect of different insect products. …”
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