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12701
Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning
Published 2025-01-01“…Based on the GSE98224 dataset, we explored the differentially expressed cuproptosis related genes (DECRGs) and immunological composition. …”
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12702
Novel Genomic Aberrations in Testicular Germ Cell Tumors by Array-CGH, and Associated Gene Expression Changes
Published 2006-01-01“…Materials and Methods: To determine the detailed DNA copy number changes, and investigate their impact on gene expression levels, we performed an integrated microarray profiling of TGCT genomes and transcriptomes. …”
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12703
Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans
Published 2025-01-01“…However, the molecular mechanisms underlying fungal clearance by phagocytes remain incompletely understood. In this study, we investigated the role of Perforin-2 (Mpeg1) in antifungal immunity. …”
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12704
Predicting nonequilibrium Green’s function dynamics and photoemission spectra via nonlinear integral operator learning
Published 2025-01-01“…We utilize RNNs to learn the nonlinear mapping between Green’s functions and convolution integrals in KBEs. …”
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12705
A ribodepletion and tagging protocol to multiplex samples for RNA-seq based virus detection: application to the cassava virome
Published 2025-02-01“…We evaluated the protocol on a series of cassava samples with a known assemblage of viruses. …”
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12706
Comparing the effectiveness, safety and tolerability of interventions for depressive symptoms in people with multiple sclerosis: a systematic review and network meta-analysis proto...
Published 2022-06-01“…The comparative efficacy and safety of intervention modalities have not been quantified.We plan to conduct a systematic review and network meta-analysis to compare efficacy and safety of psychological, pharmaceutical, physical and magnetic stimulation interventions for depression in people with MS.Methods and analysis We will search EMBASE, Medline, Cochrane CENTRAL, APA PsycINFO, Web of Science, CINAHL and PEDro from inception to 31 December 2021. …”
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12707
Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
Published 2025-02-01“…Feature selection methods such as LASSO, SVM-RFE and random forest algorithm were applied to localize possible therapeutic target genes. Finally, We analyzed the molecular pathways of CXCR4 in DFUs by Gene set enrichment analysis (GSEA).ResultsWe identified a total of 751 differential genes, of which 409 genes were significantly upregulated and 342 genes were downregulated in diabetic foot ulcer tissues. …”
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12708
GADD45β Determines Chemoresistance and Invasive Growth of Side Population Cells of Human Embryonic Carcinoma
Published 2010-01-01“…To further characterize the NEC8 SP cells, we used DNA microarrays. Among 38,500 genes, we identified 12 genes that were over-expressed in SP cells and 1 gene that was over-expressed in non-SP cells. …”
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12709
Therapeutic Approaches in Mitochondrial Dysfunction, Inflammation, and Autophagy in Uremic Cachexia: Role of Aerobic Exercise
Published 2019-01-01“…Muscle wasting was determined based on grip strength, cross-sectional area (CSA), and MyHC protein expression. We also measured mitochondrial dysfunction in mice by assessing mtDNA, ROS, ATP production, and mitochondrial configuration. …”
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12710
Suicide mortality among individuals in federal prisons compared with the general population: a retrospective cohort study in the USA from 2009 to 2020
Published 2024-06-01“…We tested for linear trends over calendar year in each population.Results In federal prisons, 245 deaths were reported as suicides from 2009 to 2020 (5% of federal prison deaths). …”
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12711
The transcription factor dFOXO controls the expression of insulin pathway genes and lipids content under heat stress in <i>Drosophila melanogaster</i>
Published 2021-09-01“…We found that neither mutation influenced dfoxo expression and its uprise under short-term heat stress, but both of them disrupted the stress response of the dilp6 and dInR genes. …”
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12712
Finding Lensed Radio Sources with the Very Large Array Sky Survey
Published 2025-01-01“…We obtain high-resolution (0 $\mathop{.}\limits^{\unicode{x02033}}$ 2) VLA follow-up observations for 11 targets that we identify using three different techniques: (i) a search for compact radio sources offset from galaxies with high lensing potential, (ii) VLASS detections of known lensed galaxies, and (iii) VLASS detections of known lensed quasars. …”
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12713
Analysis of 42 Years of Cosmic Ray Measurements by the Neutron Monitor at Lomnický štít Observatory
Published 2025-01-01“…As part of the selection of events for case studies, we report the discovery of TGE‐s visible in the data. …”
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12714
Automated skin lesion detection and prevalence estimation in Tamanend's bottlenose dolphins
Published 2025-03-01“…Manually, we do find that lesion presence in individuals suggests a positive relationship between lesion presence and gregariousness. …”
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12715
A machine learning model using the snapshot ensemble approach for soil respiration prediction in an experimental Oak Forest
Published 2025-03-01“…First, we extracted temporal features using the Prophet Forecasting model. …”
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12716
Tumor Necrosis Factor (TNF) Receptor Expression Determines Keratinocyte Fate upon Stimulation with TNF-Like Weak Inducer of Apoptosis
Published 2019-01-01“…Additionally, we found that TRAF2 exhibited binding to Fn14, cIAP1, and TNFR1/2. …”
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12717
Oral Immunisation With Non‐GMO Surface Displayed SARS‐CoV‐2 Spike Epitopes on Bacteria‐Like Particles Provokes Robust Humoral and Cellular Immune Responses, and Modulated the Gut M...
Published 2025-01-01“…After that, we evaluated its efficacy to induce immune responses in immunocompetent mice. …”
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12718
FPGA-Based Distributed Union-Find Decoder for Surface Codes
Published 2024-01-01“…The Union-Find (UF) decoder is promising with an average time complexity slightly higher than <inline-formula><tex-math notation="LaTeX">$O(d^{3})$</tex-math></inline-formula>. We report a distributed version of the UF decoder that exploits parallel computing resources for further speedup. …”
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12719
Hypertension and Its Associated Risk Factors in the Kingdom of Saudi Arabia, 2013: A National Survey
Published 2014-01-01“…Current data on hypertension in the Kingdom of Saudi Arabia are lacking. We conducted a national survey to inform decision-makers on the current magnitude of the epidemic. …”
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12720
Genomic and algorithm-based predictive risk assessment models for benzene exposure
Published 2025-01-01“…AimIn this research, we leveraged bioinformatics and machine learning to pinpoint key risk genes associated with occupational benzene exposure and to construct genomic and algorithm-based predictive risk assessment models.Subject and methodsWe sourced GSE9569 and GSE21862 microarray data from the Gene Expression Omnibus. …”
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