Comparative analysis of lactaptin activity when produced in bacterial or eukaryotic expression systems by O. A. Koval, O. Y. Volkova, A. A. Gorchakov, S. V. Kulemzin, A. V. Tkachenko, A. A. Nushtaeva, E. V. Kuligina, V. A. Richter, A. V. Taranin

“…We show that EL1-derived lactaptin is at least 100-fold more cytotoxic than RL2. …”
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Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera by Najat Bdeir, Tatjana Lüddecke, Henrike Maaß, Stefan Schmelz, Ulfert Rand, Henning Jacobsen, Kristin Metzdorf, Upasana Kulkarni, Anne Cossmann, Metodi V. Stankov, Markus Hoffmann, Stefan Pöhlmann, Wulf Blankenfeldt, Alexandra Dopfer-Jablonka, Georg M. N. Behrens, Luka Čičin-Šain

“…We use this library in an approach that we call reverse mutational scanning to define distinct neutralization titers against each epitope. …”
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Genomic selection for resistance to one pathogenic strain of Vibrio splendidus in blue mussel Mytilus edulis by Munusamy Ajithkumar, Jonathan D’Ambrosio, Marie-Agnès Travers, Romain Morvezen, Lionel Degremont

“…Additionally, we performed a genome-wide association study (GWAS) to identify putative QTLs underlying disease resistance. …”
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Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer by Rebeca San Martin, Prijoyit Das, Tianchun Xue, Morgan Rose Brown, Renata Dos Reis Marques, Michael Essington, Adrian Gonzalez, Rachel Patton McCord

“…We also present modified protocols for subculturing cells and collecting nucleic acids and protein in high-calcium samples. …”
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Understanding uncertainties in the satellite altimeter measurement of coastal sea level: insights from a round-robin analysis by F. Birol, F. Bignalet-Cazalet, M. Cancet, M. Cancet, J.-A. Daguze, W. Fkaier, E. Fouchet, E. Fouchet, F. Léger, C. Maraldi, F. Niño, M.-I. Pujol, N. Tran

“…Uncertainties associated with each of the components used to calculate the altimeter sea surface heights are estimated by measuring the spread of sea level values obtained using the various algorithms considered in the round-robin for this component. We intercompare these uncertainty estimates and analyze how they evolve when we go from the open ocean to the coast. …”
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Exploring genetic associations and drug targets for mitochondrial proteins and schizophrenia risk by Wenxi Sun, Ping Sun, Jin Li, Qun Yang, Qing Tian, Shiting Yuan, Xueying Zhang, Peng Chen, Chuanwei Li, Xiaobin Zhang

“…We conducted bidirectional two-sample Mendelian randomization (MR) analyses, with inverse variance weighting (IVW) as the primary method. …”
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Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users by Dongmei Li, Zidian Xie, Sadiya Bi Shaikh, Irfan Rahman

“…Abstract Little is known about how exclusive e-cigarette use affects exosomal microRNA (miRNA) expression, which is crucial in inflammation and disease processes like cancer. We compared exosomal miRNA profiles between exclusive e-cigarette users and non-users. …”
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Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Sever... by Bradley A. Dengler, Oliver Karam, Colleen A. Barthol, Aaron Chance, Laura E. Snider, Clare M. Mundy, Michael T. Bounajem, William C. Johnson, Moustafa M. Maita, Paola M. Mendez-Gomez, Ali Seifi, Shaheryar Hafeez

“…We identified those patients with refractory intracranial pressure who received boluses of ketamine. …”
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Empowerment resources, decision-making and gender attitudes: which matter most to livestock keepers in the mixed and livestock-based systems in Ethiopia? by Wole Kinati, Derek Baker, Elizabeth C. Temple, Dina Najjar, Annet Abenakyo Mulema

“…This is important, because we cannot talk of empowerment for those who are not in a disempowered condition or who do not value it. …”
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A novel framework unveiling the importance of heterogeneous selection and drift on the community structure of symbiotic microbial indicator taxa across altitudinal gradients in amp... by Jin Zhou, Zhidong Liu, Sishuo Wang, Jing Li, Lin Zhang, Ziyan Liao

“…In different altitude groups, we found that heterogeneous selection governed the community structure of symbiotic microbes across DSUs, while stochastic processes tended to increase with altitude. …”
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Spatial and temporal activity patterns of Amblyomma americanum by Daniel S. Marshall, Karen C. Poh, Mason V. Reichard, Lindsay A. Starkey, Jeb P. Owen

“…Using video tracking software, we measured the distance traveled and activity time in the laboratory. …”
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Development of an sRNA-mediated conditional knockdown system for Chlamydia trachomatis by Janina Ehses, Kevin Wang, Asha Densi, Cuper Ramirez, Ming Tan, Christine Sütterlin

“…ABSTRACT We describe a new Chlamydia trachomatis protein depletion method that uses an engineered small RNA (sRNA) to inhibit translation of a target gene. …”
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Oxidized LDL Induces Alternative Macrophage Phenotype through Activation of CD36 and PAFR by Francisco J. Rios, Marianna M. Koga, Mateus Pecenin, Matheus Ferracini, Magnus Gidlund, S. Jancar

“…OxLDL is recognized by macrophage scavenger receptors, including CD36; we have recently found that Platelet-Activating Factor Receptor (PAFR) is also involved. …”
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Unexpected Impact of COVID-19 Lockdown on the Air Quality in the Metro Atlanta, USA Using Ground-based and Satellite Observations by Guanyu Huang, Reyla Ponder, Amber Bond, Hailey Brim, Akua Temeng, Aaron R. Naeger, Lei Zhu

“…Abstract We studied the impact of COVID-19 (coronavirus disease 2019) lockdown on the air quality over the Atlanta area using satellite and ground-based observations, meteorological reanalysis data and traffic information. …”
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Can Thinning Foster Forest Genetic Adaptation to Drought? A Demo‐Genetic Modelling Approach With Disturbance Regimes by Victor Fririon, Hendrik Davi, Sylvie Oddou‐Muratorio, Gauthier Ligot, François Lefèvre

“…We simulated simplified thinning scenarios, tailored to even‐aged stands. …”
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Goats who stare at video screens – assessing behavioural responses of goats towards images of familiar and unfamiliar con- and heterospecifics by Deutsch, Jana, Lebing, Steve, Eggert, Anja, Nawroth, Christian

“…In our looking time paradigm, we assessed the attention of 10 female dwarf goats (Capra hircus) towards 2D visual stimuli which were images of familiar and unfamiliar con- and heterospecifics (i.e. goats and humans) using an experimental apparatus containing two video screens. …”
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Exploring diazotrophic diversity: unveiling Nif core distribution and evolutionary patterns in nitrogen-fixing organisms by Bruno Thiago de Lima Nichio, Roxana Beatriz Ribeiro Chaves, Fábio de Oliveira Pedrosa, Roberto Tadeu Raittz

“…Using this Nif database and a data mining strategy, we extended our analysis to 711 species and found that 544 contain the Nif core. …”
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Migration of primordial germline cells is negatively regulated by surrounding somatic cells during early embryogenesis in Drosophila melanogaster by N. V. Dorogova, A. S. Khruscheva, Iu. A. Galimova, D. Yu. Oshchepkov, D. E. Maslov, E. D. Shvedkina, K. A. Akhmetova, S. A. Fedorova

“…We identified the myc, Hph, stat92E, Tre-1, and hop genes, whose RNA interference leads to premature active PGC migration at stages 4–7 of embryogenesis. …”
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Comparing acceptance of smoking cessation and smoke-free home intervention offers and associated factors among people with low income in the USA: baseline results of a randomised c... by Matthew W Kreuter, Michelle C Kegler, Jennifer Wolff, Amy McQueen, Lauren Grimes, Enguday Teshome, Rachel Garg, Tess Thompson, Kelly Carpenter

“…In this randomised controlled trial, we offered both arms a tobacco quitline intervention. …”
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Local structural–functional coupling with counterfactual explanations for epilepsy prediction by Jiashuang Huang, Shaolong Wei, Zhen Gao, Shu Jiang, Mingliang Wang, Liang Sun, Weiping Ding, Daoqiang Zhang

“…Finally, we employ these patterns to identify brain disorders while refining abnormal patterns to generate counterfactual explanations. …”
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