Personalized metronomic radiopharmaceutical therapy through injection profile optimization via physiologically based pharmacokinetic (PBPK) modeling by Aryan Golzaryan, M. Soltani, Farshad Moradi Kashkooli, Babak Saboury, Arman Rahmim

“…We designed a treatment algorithm to select optimal regimens with high AD, while investigating what we term radiopharmaceutical delivery payload (RDP). …”
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Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells by Stefanie Hoyer, Kerstin F. Gerer, Isabell A. Pfeiffer, Sabrina Prommersberger, Sandra Höfflin, Tanushree Jaitly, Luca Beltrame, Duccio Cavalieri, Gerold Schuler, Julio Vera, Niels Schaft, Jan Dörrie

“…We used 16 different RNAs, encoding tumor antigens (MelanA, NRAS, BRAF, GNAQ, GNA11, and WT1), and variants thereof. …”
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Retiming dynamics of harmonically mode-locked laser solitons in a self-driven optomechanical lattice by Xiaocong Wang, Benhai Wang, Wenbin He, Xintong Zhang, Qi Huang, Zhiyuan Huang, Xin Jiang, Meng Pang, Philip. St. J. Russell

“…In addition, we show, through statistical analysis of the intra-cavity pulse spacing, how the trapping potentials are effective for suppressing timing jitter. …”
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Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…We describe the investigation into male quality and other factors that may have limited the impact of Wolbachia-male releases. …”
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Diversity, distribution and threat status of Fabaceae plants in Costa Rica: a 135-year herbarium record by Donifer Campos Parra, Andres Blanco Picado, Keilor Rojas Jimenez

“…Results: We documented the presence of 154 genera of Fabaceae, with Inga being the most abundant and diverse. …”
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Surgical Treatment and Survival in Patients with Liver Metastases from Neuroendocrine Tumors: A Meta-Analysis of Observational Studies by Stefano Bacchetti, Serena Bertozzi, Ambrogio P. Londero, Alessandro Uzzau, Enrico Maria Pasqual

“…We performed the meta-analysis for comparing surgical resection of hepatic metastases with other treatments. …”
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Sustainability assessment of single-atom catalysts in the transition to greener chemical processes by Mark A. Bajada, Maxim Tschulkow, Gianvito Vilé

“…We compared the greenhouse gas emissions and criticality factors associated with the fabrication of various catalytic entities alongside the economic implications of different synthetic routes to yield the targeted ester compound. …”
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Deep Swift/UVOT Observations of GOODS-N and the Evolution of the Ultraviolet Luminosity Function at 0.2 < z < 1.2 by Alexander Belles, Caryl Gronwall, Michael H. Siegel, Robin Ciardullo, Mat J. Page

“…We present Swift Ultraviolet Optical Telescope (UVOT) observations of the deep field GOODS-N in four near-UV filters. …”
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Urinary Exosomal Long Noncoding RNA TERC as a Noninvasive Diagnostic and Prognostic Biomarker for Bladder Urothelial Carcinoma by Chen Chen, Anquan Shang, Zujun Sun, Yuting Gao, Jingjuan Huang, Yili Ping, Wenjing Chang, Chenzheng Gu, Junjun Sun, Ping Ji, Yi Yuan, Renquan Lu, Dong Li

“…Results. We found that TERC was significantly upregulated in urinary exosomes from BLCA patients compared with those from healthy controls (P<0.0001). …”
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Dual‐fluorescence imaging and automated trophallaxis detection for studying multi‐nutrient regulation in superorganisms by Lior Baltiansky, Einav Sarafian‐Tamam, Efrat Greenwald, Ofer Feinerman

“…We follow the amount of each food type in the crop of each ant in the colony. …”
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Intermediate MCAD Deficiency Associated with a Novel Mutation of the ACADM Gene: c.1052C>T by Holli M. Drendel, Jason E. Pike, Katherine Schumacher, Karen Ouyang, Jing Wang, Mary Stuy, Stephen Dlouhy, Shaochun Bai

“…To our knowledge, c.1052C>T has not been previously reported in the literature or in any of the current databases we utilize. We hypothesize that this particular mutation in combination with p.Lys304Glu results in an intermediate clinical phenotype of MCADD.…”
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Multispecies occupancy models unravel reduced colonization probabilities in plants from the unique Amazonian cangas by Rafael de Fraga, Luiz Gustavo Rodrigues Oliveira Santos, Valeria da Cunha Tavares, Leonardo Carreira Trevelin, Maurício Takashi Coutinho Watanabe, Leandro Maioli, Samir Rolim, Carolina da Silva Carvalho

“…For 18.2 % of the species, we found negative equilibrium for both mining and control plots. …”
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Evidence from NHANES 2011–2014: a correlation between the weight-adjusted-waist index and cognitive abilities in the United States by Chan Zhao, Xintian Xu, Chunyan Hao

“…Additionally, we analyzed subgroups to check for variability.ResultsThere were 2,762 participants, including1,504 (54.45%) females and 1,258 (45.55%) males. 53.77% of them had completed high school or above, and their average age was 69.05 ± 6.62. …”
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Reform or transform? A spectrum of stances towards the economic status quo within ‘new economics’ discourses by Sam J. Buckton, Jasper O. Kenter, Nibedita Mukherjee, Sandra Waddock, Annela Anger-Kraavi, Simone Martino, Ioan Fazey, Adam P. Hejnowicz, Jane Kabubo-Mariara, Jordan O. Lafayette, Kristen Locy, Chris Scarr

“…We interpreted authors’ stances towards six key status quo themes: capitalism; neoliberalism; GDP-based economic growth; debt-based money; globalisation; and the Sustainable Development Goals (SDGs). …”
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Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients by Inbal Dahan, Evgeny Farber, Nadia Thauho, Nakhoul Nakhoul, Adi Francis, Mohamad Awawde, Andrew P. Levy, Daniel B. Kim-Shapiro, Swati Basu, Farid Nakhoul

“…We conclude that the Hp 2 type is associated with elevated s-PAP levels and low plasma nitrite levels in HD patients specifically in the DM state.…”
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Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis by Wenchang Yang, Yaxin Wang, Peng Zhang, Tao Wang, Chengguo Li, Xin Tong, Xiangyu Zeng, Yuping Yin, Kaixiong Tao, Ruidong Li

“…Furthermore, we investigated the effect of OI in Con A-induced liver injury and found that OI mitigated Con A-induced histopathological damage. …”
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Clade-specific long-read sequencing increases the accuracy and specificity of the gyrB phylogenetic marker gene by Robert G. Nichols, Emily R. Davenport

“…We show that using longer reads leads to better taxonomic resolution, lower off-target amplification, and lower error rates, which are vital for accurate estimates of codiversification.…”
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Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

“…In addition, we present novel findings that mHTT disrupts cell polarity in the photoreceptor cell layer and the retinal pigment epithelium (RPE). …”
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On the specifics of valuing effort: a developmental and a formalized perspective on preferences for cognitive and physical effort by Wolff, Wanja, Stähler, Johanna, Schüler, Julia, Bieleke, Maik

“…In a sample of N = 299 paid online workers (37% female, Mage = 38.79 ± 11.24 years), we found that people differ markedly with respect to their preferred effort allocation. …”
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Conserved Nuclear Localization Signal in NS2 Protein of Bombyx Mori Bidensovirus: A Potential Invertebrate ssDNA Virus Trait by Qian Yu, Jiaxin Yan, Ying Chen, Jinfeng Zhang, Qi Tang, Feifei Zhu, Lindan Sun, Shangshang Ma, Xiaoyong Liu, Keping Chen, Qin Yao

“…Furthermore, we identified potential NLSs in NS2 homologs in other invertebrate ssDNA viruses based on sequence analysis. …”
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