How, why, where and when people feed birds?—Spatio‐temporal changes in bird‐feeding in Finland by Purabi Deshpande, Anna Haukka, Katja Rönkä, Tuomas Aivelo, Andrea Santangeli, Rose Thorogood, Aleksi Lehikoinen

“…Additionally, we conducted an online questionnaire in 2021 (over 14,000 respondents) to examine reasons for the changes that we detected. …”
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CIME4R: Exploring iterative, AI-guided chemical reaction optimization campaigns in their parameter space by Christina Humer, Rachel Nicholls, Henry Heberle, Moritz Heckmann, Michael Pühringer, Thomas Wolf, Maximilian Lübbesmeyer, Julian Heinrich, Julius Hillenbrand, Giulio Volpin, Marc Streit

“…We developed and evaluated CIME4R in collaboration with domain experts to verify its practical usefulness.…”
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The RNA-binding protein Puf5 and the HMGB protein Ixr1 regulate cell cycle-specific expression of CLB1 and CLB2 in Saccharomyces cerevisiae. by Megumi Sato, Varsha Rana, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

“…In normal mitotic growth, Clb2 plays the central role in the G2-M progression. We previously demonstrated that the RNA-binding protein Puf5 positively regulates CLB1 expression by downregulating expression of the repressor Ixr1. …”
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Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications by Tian-Hang Yu, Yan-Yu Ding, Yan-Yu Ding, Si-Guo Zhao, Jie-Hui Zhao, Yu Gu, Dong-Hui Chen, Fang Zhang, Wen-Ming Hong, Wen-Ming Hong

“…BackgroundWe conducted an investigation into the characteristics of single-cell differentiation data in gliomas, with a focus on developing DAPK1-based prognostic markers to predict patient outcomes. …”
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Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis by Guicharnaud, Chloé, Groussier, Géraldine, Beranger, Erwan, Lamy, Laurent, Vercken, Elodie, Dahirel, Maxime

“…We found partial evidence of a pace-of-life axis at the interspecific level: species with higher fecundity also had faster development time. …”
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Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4 by Zhe Huang, Ming Wang, Yitian Chen, Hua Tang, Kuo Tang, Mingkuan Zhao, Wei Yang, Zhengjun Zhou, Junjie Tian, Wei Xiang, Shenjie Li, Qinglian Luo, Luotong Liu, Yanru Zhao, Tao Li, Jie Zhou, Ligang Chen

“…However, it remains unclear whether migrasomes can influence GBM migration and invasion. In this study, we observed the presence and formation of migrasomes in GBM cells. …”
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Abnormal methylation of Mill1 gene regulates osteogenic differentiation involved in various phenotypes of skeletal fluorosis in rats and methionine intervention by Niannian Chen, Jing Zhang, Congyu Yin, Yudan Liao, Lei Song, Ting Hu, Xueli Pan

“…Similar results were obtained in the cell experiments. Subsequently, we validated the regulation of Mill1 gene methylation using DNMT1 and TET2 enzyme inhibitors. …”
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Parameter space exploration within dynamic simulations of signaling networks by Cristina De Ambrosi, Annalisa Barla, Lorenzo Tortolina, Nicoletta Castagnino, Raffaele Pesenti, Alessandro Verri, Alberto Ballestrero, Franco Patrone, Silvio Parodi

“…We started offering an introduction to very basic aspects of molecular biology, for the reader coming from computer sciences, information technology, mathematics. …”
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The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine by Zhuoyu Xiao, Sun Liu, Zengguang Li, Jinru Cui, Hailan Wang, Zihan Wang, Qihuan Ren, Laixin Xia, Zhijian Wang, Yuan Li

“…From the m6A profiles, we identified 2,655 and 2,252 m6A modifications regulated by the maternal microbiome in the fetal brain and intestine, respectively, and we demonstrated that these m6A-modified genes were enriched in the neuro/intestinal developmental pathways, such as the Wnt signaling pathway. …”
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Exploring the efficacy of psychotherapies for depression: a multiverse meta-analysis by Eirini Karyotaki, Pim Cuijpers, Constantin Yves Plessen, Clara Miguel, Marketa Ciharova

“…Are these discrepancies a result of specific meta-analytical decisions or do most analytical strategies reaching the same conclusion?Objective We aim to solve these discrepancies by conducting a multiverse meta-analysis containing all possible meta-analyses, using all statistical methods.Study selection and analysis We searched four bibliographical databases (PubMed, EMBASE, PsycINFO and Cochrane Register of Controlled Trials), including studies published until 1 January 2022. …”
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Measurement properties of the Traumatic Brain Injury Quality of Life (TBI-QoL) and Spinal Cord Injury Quality of Life (SCI-QoL) measurement systems: a systematic review by Rebecca Ataman, Rehab Alhasani, Line Auneau-Enjalbert, Adria Quigley, Henry Ukachukwu Michael, Sara Ahmed

“…Results We included 16 studies for SCI-QoL and 14 studies for TBI-QoL. …”
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Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma by Cheng Tan, Liang Liu, Xiaoyang Liu, Ling Qi, Weiyao Wang, Guifang Zhao, Libo Wang, Yimeng Dai

“…Abstract Objective We focused on the effects of PTGS2/NF‐κB signaling pathway on the radiation resistance of glioma in the study. …”
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3D Localization of FRB 20190425A for Its Potential Host Galaxy and Implications by Da-Chun Qiang, Zhi-Qiang You, Sheng Yang, Zong-Hong Zhu, Ting-Wan Chen

“…We use FRB 20190425A and GW190425 as examples to illustrate our method. …”
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Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia by Olivia M. Depies, Qianqian Guo, Yuan Gao, Sutapa Sinha, Zhenqing Ye, Weiguo Han, Kari G. Rabe, Mingma S. Hoel, Heather C. Darby, Chuanhe Yu, Esteban Braggio, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Zhiquan Wang

“…Compared with normal B cells, we found that the enhancers specifically lost in CLL B cells are associated with the downregulation of genes involved in immune response. …”
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Evaluation of Four Multiple Imputation Methods for Handling Missing Binary Outcome Data in the Presence of an Interaction between a Dummy and a Continuous Variable by Sara Javadi, Abbas Bahrampour, Mohammad Mehdi Saber, Behshid Garrusi, Mohammad Reza Baneshi

“…Next, in a simulation study, we generated data 1000 times with a sample size of 700. …”
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Divergent values and perspectives drive three distinct viewpoints on grizzly bear reintroduction in Washington, the United States by Tara S. Easter, Anna R. Santo, Abigail H. Sage, Neil H. Carter, Kai M. A. Chan, Jason I. Ransom

“…We discuss the management implications of these findings for the North Cascades grizzly bear reintroduction, and for other large carnivore reintroductions. …”
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Discovery of reproductive tissue-associated bacteria and the modes of microbiota acquisition in male honey bees (drones) by Alexis Burks, Patrick Gallagher, Kasie Raymann

“…Overall, we discovered a set of core bacteria in the reproductive and gut tissues of conventionally reared drones and revealed that social interactions are important for the proper development of the drone microbiota. …”
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Exploring the impact of deleterious missense nonsynonymous single nucleotide polymorphisms in the DRD4 gene using computational approaches by Dipto Kumer Sarker, Pallobi Ray, Fayad Bin Abdus Salam, Shaikh Jamal Uddin

“…From the dbSNP database, we found 677 nsSNPs, and then we analyzed their functional consequences, disease associations, and effects on protein stability with fifteen in silico tools. …”
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Might Heterostyly Underlie Spider Occurrence on Inflorescences? A Case Study of Palicourea rigida (Rubiaceae), a Common Shrub from Brazilian Cerrado by Suzana Diniz, Everton Tizo-Pedroso, Denise Lange, Andréa Andrade Vilela, Danielle G. Justino, Fernanda Alves Martins, Erika Germanos, Rafael Arruda, Vanessa Stefani

“…We carried out a research on the Palicourea rigida (Rubiaceae) inflorescences, a distylous shrub of Brazilian Cerrado. …”
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Skin-associated Corynebacterium amycolatum shares cobamides by M. H. Swaney, N. Henriquez, T. Campbell, J. Handelsman, L. R. Kalan

“…Cobamides, the vitamin B12 family of cofactors, are essential for metabolism in many bacteria but are only synthesized by a fraction of prokaryotes, including certain skin-associated species. Therefore, we hypothesize that cobamide sharing mediates skin community dynamics. …”
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