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74801
Amplifying children’s leadership roles and voice in decision-making through co-production in outside of school hours care: qualitative findings from the connect promote and protect...
Published 2025-02-01“…The impact related sub-themes included the following: empowerment of children through meaningful engagement; we all have a role in the team (a space for growing leadership skills); a spark through engagement and enjoyment; and being and belonging (the impact on children’s social and emotional wellbeing).ConclusionThis is the first known qualitative study to examine the use and impact of co-production processes in OSHC—where children not only co-design but also co-plan, co-deliver, and co-evaluate the activity programming alongside OSHC educators and their communities. …”
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74802
The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors
Published 2020-01-01“…However, there are rare studies that assess the malignant risks for LSTs with colorectal polyps, which might largely contribute to further strategies of treatment and follow-up plans in LSTs. Methods. We conducted a retrospective cohort study that enrolled 206 patients with LSTs in the Endoscopy Center and Endoscopy Research Institute, Renji Hospital, Shanghai Jiao Tong University, China. …”
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74803
Targeting SRSF1 improves cancer immunotherapy by dually acting on CD8+T and tumor cells
Published 2025-01-01“…The small-molecule inhibitor TN2008 targets SRSF1, boosting antitumor immune responses and improving immunotherapy effectiveness in mouse models. We therefore introduce a paradigm targeting SRSF1 that simultaneously disrupts tumor cell metabolism and enhances the antitumor immunity of CD8+ T cells.…”
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74804
Health risk assessment through probabilistic sensitivity analysis of carbon monoxide and fine particulate transportation exposure
Published 2023-10-01“…Therefore, in this study, we aimed to evaluate the concentration of carbon monoxide and fine particulate matter in the air and their potential health risks and further examine the use of probabilistic methods to simulate the sensitivity of people living in communities and school children to these pollutants.METHODS: This study collected carbon monoxide and fine particulate matter samples from 32 stations near community houses and 14 sites near schools located along roads. …”
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74805
Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families
Published 2025-01-01“…Abstract Background Congenital muscular dystrophies (CMDs) and myopathies (CMYOs) are a clinically and genetically heterogeneous group of neuromuscular disorders that share common features, such as muscle weakness, hypotonia, characteristic changes on muscle biopsy and motor retardation. In this study, we recruited eleven families with early-onset neuromuscular disorders in China, aimed to clarify the underlying genetic etiology. …”
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74806
Hard rock aquifer architecture and water circulation levels in the Strengbach critical zone observatory (France)
Published 2023-11-01“…We present an integrated petrological, petrophysical, and hydrogeological study of the critical zone (CZ) developed in the Hercynian granitic basement of the Strengbach watershed (Vosges Massif, France) to characterize its deep architecture and water circulation levels. …”
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74807
Multi-trace elements-enriched functional drink accelerates gastric ulcer repair via the HGF/c-Met/STAT3 pathway
Published 2025-02-01“…Heavy alcohol consumption can lead to various gastrointestinal disorders, with gastric ulcers being the most prevalent. In this study, we explored the reparative effects of a functional drink (FD) enriched with trace elements (TEs) on ethanol-induced gastric ulcers in rats and elucidated its underlying mechanism. …”
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74808
Modulatory effect of Echium plantagineum oil on the n-3 LC-PUFA biosynthetic capacity of chicken (Gallus gallus)
Published 2025-02-01“…Consequently, and in alignment with our hypothesis, EO was more effective than LO in enriching chicken thigh meat with n-3 LC-PUFA (6.0 vs 4.2%; p<0.05). We concluded that lowering the dietary LA/ALA ratio and increasing the SDA content in poultry diets enhance the potential of chicken metabolism for enriching poultry products with n-3 LC-PUFA. …”
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74809
Seroprevalence and Seroconversion of Dengue and Implications for Clinical Diagnosis in Amazonian Children
Published 2014-01-01“…This study aimed to evaluate the prevalence of serum IgG dengue in children in an Amazonian population, to assess the seroconversion rate in 12 months, and to estimate how many seropositive children had a prior clinical diagnosis of dengue. We conducted a population-based study between 2010 and 2011, with children aged 6 months to 12 years that were living in the urban area of a small town in the Brazilian Amazon. …”
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74810
Diplomacy and Recruitment of Mercenaries before the Battle of Žalgiris
Published 2010-06-01“…He had relied in vain upon the promises of Sigismund and then had to face the fatal consequences of that policy. We may thus conclude that the mighty Teutonic Order in Prussia had been thrown down from the peak of power within a few weeks, because its military planning, preparations and possibilities were undermined in the diplomatic battle for power. …”
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74811
Heart failure with mildly reduced ejection fraction: retrospective study of ejection fraction trajectory risk
Published 2022-06-01“…Abstract Aims Heart failure with mildly reduced ejection fraction (HFmrEF) is associated with a favourable prognosis compared with heart failure (HF) with reduced ejection fraction (EF). We assessed whether left ventricular ejection fraction (LVEF) trajectory can be used to identify groups of patients with HFmrEF who have different clinical outcomes in a large retrospective study of patients with serial imaging. …”
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74812
Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data
Published 2012-01-01“…Using observational studies of naturalistic cognitive activities, we report a series of mixed effects models that include baseline and change in cognitive activity predicting cognitive outcomes over up to 21 years in four longitudinal studies of aging. …”
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74813
Human Capital, Economic Growth and Environmental Quality with Special Emphasis on Public Education Expenditures: An Application of DSGE Models
Published 2024-12-01“…Discussion and Conclusion In justifying these results, we can point to the weak institutional quality in Iran, that despite the huge amount of human capital investment, there is no necessary effectiveness in the environmental sector, and this is a confirmation that Iran is in the early stages of economic development. …”
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74814
Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy
Published 2025-01-01“…However, previous studies in China have mostly focused on the relationship between short IPIs and adverse perinatal outcomes, while neglecting maternal age as a potential confounder. Methods We conducted a retrospective cohort study of 23,899 pregnant women who delivered between January 1, 2017 and December 31, 2019 at Chengdu Women’s and Children’s Central Hospital and West China Second Hospital of Sichuan University. …”
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74815
Segmentasi Citra X-Ray Dada Menggunakan Metode Modifikasi Deeplabv3+
Published 2023-07-01“…To make it easier to make a diagnosis, we need a deep learning model that can help with this. …”
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74816
Fusion of EEG and EMG signals for detecting pre-movement intention of sitting and standing in healthy individuals and patients with spinal cord injury
Published 2025-01-01“…This study proposes a multimodal fusion method based on EEG–EMG functional connectivity to detect sitting and standing intentions before movement execution, enabling timely intervention and reducing latency in rehabilitation devices.MethodsEight healthy subjects and five spinal cord injury (SCI) patients performed cue-based sit-to-stand and stand-to-sit transition tasks while EEG and EMG data were recorded simultaneously. We constructed EEG–EMG functional connectivity networks using data epochs from the 1.5-s period prior to movement onset. …”
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74817
Thermal Variability in the Martian Upper Atmosphere within the Crustal Magnetic Field Region Induced by Gravity Wave Dissipation Due to Ion-drag Effect
Published 2025-01-01“…During this effect process, the collisions between neutral particles and ions transfer wave momentum along the magnetic field lines, and lead to wave dissipation and energy release to heat or cool the background atmosphere. We developed a one-dimensional linear wave model to describe the effect of ion-drag on wave propagation and dissipation in the Martian upper atmosphere. …”
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74818
Clinical Outcomes of Transcatheter Aortic Valve Replacement in Nonagenarians: A Systematic Review and Meta-Analysis
Published 2019-01-01“…Previous studies have reported conflicting results regarding the clinical outcomes between nonagenarians and younger patients who underwent TAVR. Methods. We searched PubMed, EMBASE, and Cochrane Library databases with predefined criteria from the inception dates to July 8, 2018. …”
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74819
Miniopen Oblique Lateral L5-S1 Interbody Fusion: A Report of 2 Cases
Published 2014-01-01“…Extreme lateral interbody fusion (XLIF) has been widely used for minimally invasive anterior lumbar interbody fusion (ALIF), but an approach to L5-S1 is difficult because of the iliac crest. In the current study, we present 2 cases using minimally invasive oblique lateral interbody fusion (OLIF) of L5-S1. …”
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74820
Differential Role of NKG2A/HLA-E Interaction in the Outcomes of Bladder Cancer Patients Treated with <i>M. bovis</i> BCG or Other Therapies
Published 2025-01-01“…Biomarkers are necessary to optimize the use of these therapies. <b>Methods</b>: We evaluated killer-cell immunoglobulin-like receptors (KIRs) and HLA-I genotyping and the expression of NK cell receptors in circulating T and NK lymphocytes at diagnosis in 325 consecutive BC patients (151 treated with BCG and 174 treated with other therapies), as well as in 648 patients with other cancers and 973 healthy donors as controls. …”
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