Impact of surgical site infection (SSI) following gynaecological cancer surgery in the UK: a trainee-led multicentre audit and service evaluation by Rachel L O’Donnell, Georgios Angelopoulos, James P Beirne, Ioannis Biliatis, Helen Bolton, Melissa Bradbury, Elaine Craig, Ketan Gajjar, Michelle L Mackintosh, Wendy MacNab, Thumuluru Kavitha Madhuri, Mark McComiskey, Eva Myriokefalitaki, Claire L Newton, Nithya Ratnavelu, Sian E Taylor, Amudha Thangavelu, Sarah A Rhodes, Emma J Crosbie, Richard J Edmondson, Yee-Loi Louise Wan

“…Our aim was to perform the first national audit of SSI following gynaecological cancer surgery through the establishment of a UK-wide trainee-led research network.Design and setting In a prospective audit, we collected data from all women undergoing laparotomy for suspected gynaecological cancer at 12 specialist oncology centres in the UK during an 8-week period in 2015. …”
Get full text

Predicting prognosis using stroke-heart indicator: brain natriuretic peptide in patients with aneurysmal subarachnoid hemorrhage by Jionghao Xue, Jionghao Xue, Fa Lin, Fa Lin, Minghao Liu, Minghao Liu, Wenxiong Song, Wenxiong Song, Runting Li, Runting Li, Yu Chen, Yu Chen, Jun Yang, Jun Yang, Heze Han, Heze Han, Yitong Jia, Yitong Jia, Xiaolin Chen, Xiaolin Chen, Rong Wang, Rong Wang, Yuanli Zhao

“…Univariable and multivariable logistic regression analyses were conducted to examine the association between BNP levels and prognosis. Additionally, we assessed the potential impact of incorporating BNP into a predictive model for poor prognosis.ResultsThe statistical analysis encompassed a total of 932 patients. …”
Get full text

Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics by Wei Lei, Yan Wu, Yan Wu, Hao Yuan, Ping He, Jingqi Wu, Jingrong Chen, Yuxiao Liu, Hongmei Zhang, Joost D. de Bruijn, Xuerong Xiang, Ping Ji, Huipin Yuan, Huipin Yuan, Mingzheng Li

“…Critical-size bone defects (CSDs), which are those that do not self-repair in a given period, are essential for evaluating bone-regeneration strategies. We established CSDs models in the rabbit cranium and ulna, and the bone-regeneration capacities of porous calcium phosphate (CaP) ceramics were assessed. …”
Get full text

Unequal ageing: the quality of life of senior citizens in the EU before and after COVID-19. A multidimensional approach by Elżbieta Roszko-Wójtowicz, Klaudia Przybysz, Agnieszka Stanimir

“…The research seeks to answer the following question: How has the quality of life among seniors in the EU evolved over time, and how has the COVID-19 pandemic affected this trajectory? We hypothesize that the pandemic has exacerbated existing socio-economic inequalities, particularly affecting the most vulnerable older populations.MethodsThis study utilises the Synthetic Measure of Senior Quality of Life (SMSQoL) to evaluate the living conditions of seniors across four critical domains: health, finances, social relations, and environment. …”
Get full text

Oral-Delivery Lactococcus lactis expressing cherry fusion lactoferrin peptides against infection of avian pathogenic Escherichia coli in chickens by Zhuoran Li, Xueying Wang, Dianzhong Zheng, Fuzhen Han, Yue Li, Han Zhou, Jiaxuan Li, Wen Cui, Yanping Jiang, Xiaona Wang, Weichun Xie, Lijie Tang

“…Lactococcus lactis (L. lactis) is an excellent vector for delivering recombinant proteins. In this research, we generated a recombinant L. lactis strain MG1363 expressing lactoferrin peptides, which was labeled with a fluorescent marker mCherry and lacked an antibiotic resistance gene (LL-EFLmC). …”
Get full text

The authority of the printed word in the Lithuanian village of the XIX century by Džiuljeta Maskoliūnienė

“…Kavolis, reasoning the issue where the authority of culture originates (the book—a concurrent attribute of culture), raises the following topical aspects: 1) "some elements of culture become reliable, important to human behavior," 2) "the authority of culture can originate from the power of its structure and its coherence. <...> We feel striking power which is in the very text or rite of culture." …”
Get full text

The Inventory of the Estate farm Senkoniai by Stasys Pamerneckis, Roberta Sakalauskaitė

“…However, from the contents, we can presume not a rope, but that valakas was used for measuring. …”
Get full text

Travellers’ adherence to atovaquone/proguanil malaria chemoprophylaxis after return from endemic areas by Jenny Lea Schnyder, David Cornelis Birkhoff, Myrthe Celine Jarings, Sabine Margot Hermans, Martin Peter Grobusch, Hanna Katrien de Jong

“…Besides being more cost-effective, shorter AP regimens may enhance adherence. We aimed to investigate adherence to the current AP chemoprophylaxis regimen during the seven days post-travel, and travellers’ preferences for potential drug-sparing AP regimens. …”
Get full text

Deciphering the functional roles of PE18 and PPE26 proteins in modulating Mycobacterium tuberculosis pathogenesis and immune response by Aquib Ehtram, Mohd Shariq, Neha Quadir, Neha Quadir, Salma Jamal, Manjunath Pichipalli, Sheeba Zarin, Sheeba Zarin, Javaid Ahmad Sheikh, Nasreen Z. Ehtesham, Seyed E. Hasnain, Seyed E. Hasnain

“…Despite their importance, the roles and molecular interactions of PE18 and PPE26 in Mtb pathogenesis require further investigation.MethodsWe explored the roles of PE18 and PPE26 using recombinant Mycobacterium smegmatis (Msmeg) as a model organism. …”
Get full text

Monitoring the Spread of Multidrug-Resistant <i>Escherichia coli</i> Throughout the Broiler Production Cycle by Victor Dellevedove Cruz, Danilo Henrique Rabaçal Alves, Jamile Kellen de Souza, Maísa Fabiana Menck-Costa, Bruno Henrique Dias de Oliva, Ana Angelita Sampaio Baptista, Alexandre Oba, Fabrizio Matté, Kácio Emílio Borges Baierle, Sérgio Paulo Dejato da Rocha, Kelly Cristina Tagliari de Brito, Benito Guimarães de Brito, Gerson Nakazato, Marcio Costa, Renata Katsuko Takayama Kobayashi

“…This work aimed to monitor broiler farms in southern Brazil, isolating samples of <i>E. coli</i> and classifying them according to the profile of resistance to antimicrobials of interest to human and animal health. We also monitored the profile of virulence genes and conducted an epidemiological survey of possible risk factors that contribute to this selection of multidrug-resistant isolates. …”
Get full text

Age-Related Water Use Pattern of the Introduced Species Atriplex canescens Was Influenced by Root Distribution in Desert by Hai Zhou, Xiangyan Feng, Zhibin He, Bing Liu, Fang Li, Heng Ren, Qiyue Yang, Jianjun Kang, Shuai Wang, Wenzhi Zhao

“…However, little is known about the dynamics of root water uptake and age-related water sources for the shrubs, which restricts the efficacy of vegetation restoration. Here, we examined the distribution of roots and isotopic values of δ18O and δD in soil water at depths ranging from 0 to 300 cm, groundwater, precipitation, and shrub xylem at different stages of shrub maturity to determine water use patterns in shrub plantations. …”
Get full text

Les aqueducs de Lyon à l’approche de la ville antique by Emmanuelle Dumas

“…However, because of the significant levelling of its remains, we cannot estimate the altitude of the aqueduct channel in this sector. …”
Get full text

A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases by Anthony C. Nichols, Michelle Chan-Seng-Yue, John Yoo, Sumit K. Agrawal, Maud H. W. Starmans, Daryl Waggott, Nicholas J. Harding, Samuel A. Dowthwaite, David A. Palma, Kevin Fung, Bret Wehrli, S. Danielle MacNeil, Philippe Lambin, Eric Winquist, James Koropatnick, Joe S. Mymryk, Paul C. Boutros, John W. Barrett

“…We describe the presentation, management, and clinical outcome of a massive acinic cell carcinoma of the parotid gland. …”
Get full text

Multi-spatial urban function modeling: A multi-modal deep network approach for transfer and multi-task learning by Zhaoya Gong, Chenglong Wang, Bin Liu, Binbo Li, Wei Tu, Yuting Chen, Zhicheng Deng, Pengjun Zhao

“…Using Shenzhen city as a testbed, extensive experimental results show that our approach improves accuracy by 13.3% compared to state-of-the-art models. We further validate the superior generalizability of our approach across various urban tasks, such as predicting urban land-use, housing prices, and population density, over other baselines. …”
Get full text

Dynamic functional connectivity patterns predict early antidepressant treatment response in drug-naïve, first-episode adolescent MDD by Maojia Ran, Hang Zhang, Meijiang Jin, Yuanmei Tao, Hanmei Xu, Shoukang Zou, Zhujun Wang, Fang Deng, Lijuan Huang, Hong Zhang, Xiaowei Tang, Yanping Wang, Xia Fu, Li Yin, Li Yin, Li Yin

“…The aim of this study is to investigate whether dFC patterns will be changed by antidepressant treatment, as well as whether baseline dFC pattern could predict treatment response in adolescent MDD patients.MethodWe included 35 drug-naïve, first-episode MDD adolescents (age 14.40 ± 1.24; 8 males and 27 females) and 24 healthy controls (HCs, age 14.21 ± 1.41; 11 males and 13 females). …”
Get full text

The effect of groundwater depth on topsoil organic matter mineralization during a simulated dry summer in northwestern Europe by A. Françoys, A. Françoys, O. Mendoza, J. Hu, P. Boeckx, W. Cornelis, S. De Neve, S. Sleutel

“…In this study, undisturbed 200 cm long soil columns with three different textures (loamy sand, sandy loam and silt loam) were subjected to two artificial GWT depths (<span class="inline-formula">−165</span> and <span class="inline-formula">−115</span> cm) in the laboratory. We examined (1) upward moisture flow by capillary action along the soil profile, specifically into the top 20 cm of soil, and (2) the effect of the GWT on the decomposition of an added <span class="inline-formula">¹³C</span>-enriched substrate (ryegrass) over a period of 10 weeks, with limited wetting events representing a dry summer. …”
Get full text

Dynamic recrystallization mechanism of high-strength Mg-Gd-Y-Zn-Mn alloy by hot compression deformation by Yini Lin, Shiming Wu, Yongxin Wang, Hao Chen, Guo Li, Weidong Xie, Guobing Wei, Yan Yang, Xiaodong Peng

“…The Mg-8Gd-3.5Y-1.5Zn-0.8Mn (wt%) alloy was designed and prepared to investigate the synergistic dynamic recrystallization (DRX) mechanism at high temperature and low strain rate. We studied DRX process at different strain rates and temperatures, and revealed the corresponding mechanisms. …”
Get full text

Probiotics in the Management of Chronic Bacterial Prostatitis Patients: A Randomized, Double-Blind Trial to Evaluate a Possible Link Between Gut Microbiota Restoring and Symptom Re... by Cristina Vocca, Diana Marisol Abrego-Guandique, Erika Cione, Vincenzo Rania, Gianmarco Marcianò, Caterina Palleria, Luca Catarisano, Manuela Colosimo, Gregorio La Cava, Italo Michele Palumbo, Giovambattista De Sarro, Tommaso Ceccato, Simone Botti, Tommaso Cai, Alessandro Palmieri, Luca Gallelli

“…In this randomized, placebo-controlled clinical study, we evaluated the efficacy and safety of consumption of probiotics containing human <i>Lactobacillus casei</i> DG^® as an add-on treatment in patients with clinical recurrences of CBP, through gut microbiota modification analysis. …”
Get full text

A Metapopulation Model to Assess Water Management Impacts on the Threatened Australian Lungfish, <i>Neoceratodus forsteri</i> by Charles R. Todd, Andrew J. McDougall, Scott M. C. Raymond, Robin Hale, Timothy R. Brown, John D. Koehn, Henry F. Wootton, Steven G. Brooks, Adrian M. Kitchingman, Tom Espinoza, Benjamin G. Fanson, Peter K. Kind, Sharon M. Marshall, David T. Roberts

“…Through a pre-development streamflow, we quantify the impact of high regulation and development on the lungfish population in the Burnett River: a minor decline in the upstream population (e.g., 9.8% decline), a large decline in the middle population (64.2% decline), virtually no change in the downstream population (e.g., 1.2% decline) and a moderate decline in the overall metapopulation (e.g., 22.3% decline). …”
Get full text

Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus) by Lei Zhang, Wanting Zhang, Yingyin Cheng, Yutong Fang, Xin Guan, Ao Gong, Yanxin Jiang, You Duan, Lei Huang, Waqar Younas, Yaping Wang, Mijuan Shi, Xiao-Qin Xia

“…However, the lack of a high-quality reference genome has hindered further research. In this study, we performed PacBio HiFi and Hi-C sequencing on a female (ZW) specimen and assembled the first high-quality chromosome-level genome of the large-scale loach. …”
Get full text