Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration- Tobacco w... by Erfan Tasdighi, Kunal K. Jha, Zeina A. Dardari, Ngozi Osuji, Tanuja Rajan, Ellen Boakye, Michael E. Hall, Carlos J. Rodriguez, Andrew C. Stokes, Omar El Shahawy, Emelia J. Benjamin, Aruni Bhatnagar, Andrew P. DeFilippis, Michael J. Blaha

“…The definitions of the variables in each cohort were systematically evaluated by a team of two physician-scientists and a biostatistician. Herein, we describe the method of data acquisition and harmonization and the baseline sociodemographic and risk profile of participants in the combined CCC-Tobacco dataset. …”
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Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards by Cosima Strantz, Dominik Böhm, Thomas Ganslandt, Melanie Börries, Patrick Metzger, Thomas Pauli, Andreas Blaumeiser, Alexander Scheiter, Ian-Christopher Jung, Jan Christoph, Iryna Manuilova, Konstantin Strauch, Arsenij Ustjanzew, Niklas Reimer, Hauke Busch, Philipp Unberath

“…Results Using quantitative and qualitative analyses, we show that existing digital tools may improve therapy recommendations and streamline MTB case preparation, while continuous training and system improvements are needed. …”
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Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa by Nelson Bergonse Neto, Lianna Ferrari Jorge, Julio C. Francisco, Bruna Olandoski Erbano, Barbara Evelin Gonçalves Barboza, Larissa Luvison Gomes da Silva, Marcia Olandoski, Katherine Athayde Teixeira de Carvalho, Luiz Felipe Pinho Moreira, Jose Rocha Faria Neto, Eltyeb Abdelwahid, Luiz Cesar Guarita-Souza

“…Animals in the control group underwent only surgical tracheostomy, while animals in the SIS group underwent surgical tracheostomy with an SIS graft covering the defect. We examined tissues at the site of tracheostomy 60 days after surgery using histological analysis with hematoxylin and eosin (H&E) staining and analyzed the perimeter and area of the defect with Image-Pro® PLUS 4.5 (Media Cybernetics). …”
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Rapid Detection of the mt3243A > G Mutation Using Urine Sediment in Elderly Chinese Type 2 Diabetic Patients by Yinan Zhang, Xiujuan Du, Xinqian Geng, Chen Chu, Huijuan Lu, Yixie Shen, Ruihua Chen, Pingyan Fang, Yanmei Feng, Xiaojie Zhang, Yan Chen, Yanping Zhou, Congrong Wang, Weiping Jia

“…Objective. In this study, we aimed to identify mt3243A > G mutation carriers in a group of Chinese elderly type 2 diabetic patients by a rapid and noninvasive diagnostic system. …”
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Intracardiac Fibrinolysis and Endothelium Activation Related to Atrial Fibrillation Ablation with Different Techniques by Orsolya Hajas, Zsuzsa Bagoly, Noémi K Tóth, Réka Urbancsek, Alexandra Kiss, Kitti B Kovács, Ferenc Sarkady, Attila Nagy, Anna V. Oláh, László Nagy, Marcell Clemens, László Csiba, Zoltán Csanádi

“…The effect of pulmonary vein isolation (PVI) on fibrinolytic and endothelial activation with currently applied periprocedural anticoagulation has not been explored. We measured markers of fibrinolysis and endothelium activation before and after PVI with the second-generation cryoballoon (Cryo), pulmonary vein ablation catheter (PVAC-Gold), and irrigated radiofrequency (IRF). …”
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Wound irrigation and peritoneal lavage with antiseptic/antibiotic solution before wound closure during gastrointestinal surgery: a systematic review and meta-analysis by Motoi Uchino, Koji Tamura, Shinsuke Nomura, Seiichi Shinji, Keita Kouzu, Hiroji Shinkawa, Tomohiro Ishinuki, Toru Mizuguchi, Hiroki Ohge, Seiji Haji, Junzo Shimizu, Yasuhiko Mohri, Chizuru Yamashita, Yuichi Kitagawa, Katsunori Suzuki, Motomu Kobayash, Masahiro Kobayashi, Yuki Hanai, Hiroshi Nobuhara, Hiroki Imaoka, Masahiro Yoshida, Toshihiko Mayumi, Hiroki Ikeuchi, on behalf of SSI Prevention Guideline Committee in Japan Society for Surgical Infection

“…Although it has recently been reported that washing with antiseptic/antibiotic solution can prevent SSI in clean surgery, the clinical impact in gastrointestinal surgery is still uncertain. Therefore, we performed a systematic review and meta-analysis to evaluate the efficacy of antiseptic/antibiotic solution during wound irrigation or peritoneal lavage in gastroenterological surgery. …”
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Sensory acceptability of buffalo meat compared to beef by Luis A. de la Cruz-Cruz, Cristian Larrondo-Cornejo, Patricia Roldán-Santiago, René Rodríguez-Florentino

“…The panelist highlighted various reasons why buffalo meat is not commonly consumed, such as there is no information on buffalo meat (93.42%/n=71), there are not many products made with buffalo meat (60.52%/n =46), and that it is not available at supermarkets (73.69%/n=56). We conclude that buffalo meat can be a good option for consumers. …”
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Evidence linking phthalate exposure to alterations of hematologic parameters in Chinese children: A cross-sectional study by Mei-Ting Wei, Ying Wen, Zhu-Xia Zhang, Xiu-Ju Liu, Feng-Xiang Wei, Wei-Qiang Liu, Li Zhou, Ding-Yan Chen, Yao Yao

“…School-aged children are a particularly susceptible population to phthalate exposure, yet research examining the correlation between combined exposure to multiple phthalates and hematologic changes is limited. We explored the individual and joint associations of early childhood phthalate exposure with hematologic parameters. …”
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Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

“…To investigate whether PrPC mediates TauO detrimental activities, we compared their effects on memory and synaptic plasticity in wild type (WT) and PrPC knockout (Prnp 0/0) mice. …”
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Impact of Annually Variable Dust Activity on the Recession of the Martian South Polar Seasonal Cap by Zhibin Li, Jianjun Liu, Renhao Tian, Zhaopeng Chen, Qing Zhang, Jingjing Zhang, Wei Yan, Qiang Fu, Shaoran Liu, Nannan Ma

“…Continuous observations of SPSC/South Polar Residual Cap (SPRC) across several Martian years, alongside segmented analyses of annual dust activity, will provide new insights into the climate conditions of Martian south polar region. Here, we performed a combined analysis on the extents of SPSC from MY28-MY31 and MY36, together with the concurrent Martian atmospheric optical thickness, to assess the influence of dust activity at various recession time steps. …”
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The OsEBF1-OsEIL5-OsPP91 module regulates rice heat tolerance via ubiquitination and transcriptional activation by Jianping Liu, Ke Wang, Guining Wang, Zhi Peng, Tao Wang, Yang Meng, Jinli Huang, Jiaohan Huo, Xin Li, Xiaoqi Zhu, Feiyun Xu, Qian Zhang, Zhengrui Wang, Hao Chen, Ya Wang, Weifeng Xu

“…Summary: Understanding the regulatory mechanisms underlying the plant heat stress response is important for developing climate-resilient crops, including rice (Oryza sativa). Here, we report that OsEIL5, one member of the ETHYLENE INSENSITIVE3-LIKE family, positively regulates rice heat tolerance at the seedling and reproductive stages. …”
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Relationship Among Macronutrients, Dietary Components, and Objective Sleep Variables Measured by Smartphone Apps: Real-World Cross-Sectional Study by Jaehoon Seol, Masao Iwagami, Megane Christiane Tawylum Kayamare, Masashi Yanagisawa

“…ObjectiveThis cross-sectional study aimed to examine the associations between macronutrients, dietary components, and sleep parameters, considering their interdependencies. MethodsWe analyzed data from 4825 users of the Pokémon Sleep and Asken smartphone apps, each used for at least 7 days to record objective sleep parameters and dietary components, respectively. …”
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The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman  Pinschers of efficacy and outcomes by Sabine Werner, Gerd Wallukat, Niels‐Peter Becker, Katrin Wenzel, Johannes Müller, Ingolf Schimke, Gerhard Wess

“…Using a natural large animal model of DCM considered superior to small animal models of immunization‐induced cardiomyopathy, combined with a study design comparable with clinical trials, we believe that our results provide the basis for optimism that treatment with BC 007 might also be effective in human patients with DCM.…”
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Factors associated with the revolving door phenomenon in patients with schizophrenia: results from an acute psychiatric hospital in Romania by Vlad Dionisie, Vlad Dionisie, Maria Gabriela Puiu, Maria Gabriela Puiu, Mihnea Costin Manea, Mihnea Costin Manea, Emanuel Moisa, Ana Maria Dumitru, Leila Ibadula, Aliss Madalina Mares, Aliss Madalina Mares, Corina Ioana Varlam, Mirela Manea, Mirela Manea

“…Therefore, this research aimed to identify socio-demographic and clinical factors associated with the revolving door phenomenon in patients with schizophrenia.MethodsWe conducted an observational and retrospective cohort study and collected data from the medical records of individuals admitted to the largest psychiatric hospital in Romania during a 2-year period. …”
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Detection of Integrase Gene in E. coli Isolated from Pigs at Different Stages of Production System by Eulalia de la Torre, Rocío Colello, Nora Lía Padola, Analía Etcheverría, Edgardo Rodríguez, Fabián Amanto, María Ofelia Tapia, Alejandro Luis Soraci

“…From environmental samples 78.4% of E. coli containing any integron class was detected. We conclude that animals and farm environment can act as reservoirs for potential spread of resistant bacteria by means of mobile genetic elements as integrons, which has a major impact on production of food animals and that can reach man through the food chain, constituting a problem for public health.…”
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Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model by Cheuk-Kwan Sun, Yen-Yi Zhen, Hung-I Lu, Pei-Hsun Sung, Li-Teh Chang, Tzu-Hsien Tsai, Jiunn-Jye Sheu, Yung-Lung Chen, Sarah Chua, Hsueh-Wen Chang, Yi-Ling Chen, Fan-Yen Lee, Hon-Kan Yip

“…We tested the hypothesis that Lipofectamine siRNA delivery to deplete transient receptor potential cation channel (TRPC) 1 protein expression can suppress hypoxia-induced pulmonary arterial hypertension (PAH) in mice. …”
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Practice, Knowledge, and Attitude of Health Care Providers regarding Cancer Pain Management: A National Survey by Jinmei Liu, Ming Zhang, Juan Luo, Jiyi Xie, Xu Chen, Hanxiang Wang, Shijun Li, Shengli Yang, Chunfen Peng, Liangle Yang, Bin Deng, Yu Zhang, Cong Wang, Jianli Hu, Chen Shi

“…An open online survey was adopted using social media software (WeChat) as the platform to conduct a nationwide survey of HCPs involved in CPM in public medical institutions at all levels in China from March to June 2019. …”
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Association Between Urinary Metal Levels and Chronic Kidney Dysfunction in Rural China: A Study on Sex-Specific Differences by Kaisheng Teng, Qinyi Guan, Qiumei Liu, Xiaoting Mo, Lei Luo, Jiahui Rong, Tiantian Zhang, Wenjia Jin, Linhai Zhao, Songju Wu, Zhiyong Zhang, Jian Qin

“…Least absolute shrinkage and selection operator (LASSO) regression was employed to identify metals significantly associated with CKD. Then, we used binary logistic regression, along with restricted cubic spline (RCS) models, to assess the individual exposure effects of specific metals on CKD. …”
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Scaling climate information services and climate smart agriculture through bundled business models by Desire M. Kagabo, Livingstone Byandaga, Patrick Gatsinzi, Patrick Mvuyibwami, Yvonne U. Munyangeri, Nasson Ntwari, Mathieu Ouedraogo

“…Drawing on the synthesis analysis of available relevant publications, we devised a 1–5 scale evaluation framework based on nine scaling readiness indicators—technology, impact, bundling, infrastructure, relevance, evidence, barriers, sustainability, and value addition—to assign scalability scores to 29 business cases with bundled CIS-CSA products and services across Africa and Asia. …”
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Morphological Comparisons of Adult Worker Bees Developed in Chinese and Italian Honey Bee Combs by Shunhua Yang, Hui Li, Pingqing Wu, Dan Yue, Yulong Guo, Wenzheng Zhao, Kun Dong

“…Workers emerging from the control and treatment combs were designated as control and treatment workers, respectively. We compared 13 external morphological traits, including right forewing length and width; linear length of veins a, b, c, and d; proboscis length; right hind femur length; tibia length; metatarsal length and width; and the longitudinal diameters of the third and fourth tergites between the two groups. …”
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