Comprehensive coronary CT angiography in people living with HIV: a systematic review and meta-analysis by Binh T Nguyen, Edward Hulten, Venkatesh L Murthy, Tarin Phillips, Gregory M Blake, Jonathan A Aun, Lisa M Conte, Ritika Gadodia, Aakash Tuli, Sara L Robinson, Travis E Harrell

“…This systematic review and meta-analysis summarise and estimate pooled effect sizes for observational studies among PLWH using comprehensive coronary CT angiography (CTA).Design Preferred Reporting Items for Systematic Review and Meta-analysis reporting guidelines were used.Data sources PubMed, Embase, Web of Science, CINAHL, Cochrane Clinical Trials and EBM were searched from inception to 23 February 2024.Eligibility criteria We included studies evaluating coronary atherosclerosis in adult PLWH with controls and CTA results for plaque prevalence, extent, severity and high-degree stenosis.Data extraction and synthesis Two independent reviewers used standardised methods to screen for relevance by title, abstract and full-text review. …”
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The control effect and induced disease resistance mechanism of Bacillus tequilensis on wheat powdery mildew by Qiuyan Bi, Fen Lu, Jie Wu, Xiangyu Liu, Xiuying Han, Jianjiang Zhao

“…Using transcriptome technology, we determined the differences in wheat gene expression in after treatment with B. tequilensis and verified the main molecular mechanism of B. tequilensis-induced resistance. …”
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Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy by Hafiza Kashaf Tariq, Zihao Liang, Lawan Rabiu, Abdulrahman Ibrahim, Nada Mohamady Farouk Abdalsalam, Rong Li, Qiong Yang, Xiaochun Wan, Dehong Yan

“…However, whether blocking the intrinsic ferroptosis pathways of MDSCs can relieve imidazole ketone erastin (IKE)-initiated ferroptosis-induced immune suppression and ultimately trigger the optimal therapeutic effect of the combined ferroptosis and ICB therapy is still unknown. Here, we report that TIPE2, a phospholipid transfer protein, regulated the ferroptosis susceptibility in MDSCs through reprogramming lipid peroxidation-related phosphatidylethanolamine (PE) and phosphatidylcholine (PC) species composition. …”
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Network Design and Route Analysis Using Outside Plant by Isaac Adjaye Aboagye, Nii Longdon Sowah, Wiafe Owusu-Banahene, Aryee Shaelijah, Margaret Ansah Richardson, Emmanuel Baah-Boadi

“…To demonstrate our methodology, we provided fiber to the home (FTTP) to an apartment located in the capital city of Ghana. …”
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Molecular and pharmacological heterogeneity of ETV6::RUNX1 acute lymphoblastic leukemia by Zhenhua Li, Huanbin Zhao, Wenjian Yang, Maud Maillard, Satoshi Yoshimura, Yu-Chih Hsiao, Xin Huang, Yoshihiro Gocho, Lauren Rowland, Anthony Brown, Landon Choi, Kristine R. Crews, Charles G. Mullighan, Samuel W. Brady, Cheng Cheng, Ti-Cheng Chang, Gang Wu, Mignon L. Loh, Allen Eng Juh Yeoh, Federico Antillon-Klussmann, Sima Jeha, Hiroto Inaba, Jiyang Yu, Ching-Hon Pui, Seth E. Karol, William E. Evans, Jun J. Yang

“…Profiling the genomic and pharmacological landscape of 194 pediatric ETV6::RUNX1 ALL cases, we uncover two transcriptomic clusters, C1 (61%) and C2 (39%). …”
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Advances in plant-based raw materials for food 3D printing by Zhihao Liu, Xinna Hu, Shuyu Lu, Bo Xu, Chenyu Bai, Tao Ma, Yi Song

“…To facilitate a more comprehensive understanding of the application of plant-based food raw materials in food 3D printing, we classified inks into molten, soft, and hydrogel materials according to their state of existence and rheological properties under different conditions. …”
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Risk of neonatal SARS-CoV-2 infection: a retrospective cohort study based on infected mothers with gestational diabetes mellitus by Jing Ni, Yongfei Zheng, Jiaqi Tian, Jiaqi Tian, Jiaqi Tian, Lin Zhang, Lin Zhang, Lin Zhang, Shuyin Duan

“…Logistic regression analysis identified an interaction between maternal SARS-CoV-2 infection and GDM on neonatal infection, where maternal SARS-CoV-2 infection (odds ratio [OR] = 0.31, 95%CI: 0.22-0.44) and vaccination for anti-SARS-CoV-2 (OR = 0.70, 95%CI: 0.50-0.98) were associated with lower odds of neonatal infection, while higher pre-pregnancy body mass index (BMI) (OR = 1.06, 95% CI: 1.02-1.10) and GDM (OR = 1.97, 95%CI: 1.21-3.21) were associated with higher odds of neonatal infection.ConclusionsWe demonstrate that the coexistence of GDM and perinatal SARS-CoV-2 infection was associated with an increased probability of neonatal SARS-CoV-2 infection.…”
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The Multifaceted Roles of Myrrha in the Treatment of Breast Cancer: Potential Therapeutic Targets and Promises by Anwar Shams MD, MSc, PhD, Abdullah Ahmed Alzahrani, Taghreed A Ayash MSc, PhD, Shadi Tamur MD, FRCPC, FAAP, Majed AL-Mourgi MD, FRCS, FCCP, FACS

“…Nonetheless, myrrh’s precise rudimentary mechanisms of action in regulating genes involved in breast cancer evolution and progression remain elusive. Purpose: Herein, we use a network pharmacology platform to identify the potential genes targeted by myrrh-active molecules in breast cancer. …”
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TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis by Ai-Ting Yang, Dou-Dou Hu, Ping Wang, Min Cong, Tian-Hui Liu, Dong Zhang, Ya-Meng Sun, Wen-Shan Zhao, Ji-Dong Jia, Hong You

“…In this study, both in vitro (HPCs cocultured with hepatic stellate cells (HSCs) in transwells) and in vivo (CCl4-injured liver fibrosis rat) systems were used to evaluate the impacts. We found that HPCs pretreated with TGF-β1 for 12 hours inhibited the activation of HSCs, while sensitization for 48 hours increased the activation of HSCs. …”
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Assessment of six insulin resistance surrogate indexes for predicting stroke incidence in Chinese middle-aged and elderly populations with abnormal glucose metabolism: a nationwide... by Luqing Jiang, Tengxiao Zhu, Wenjing Song, Ying Zhai, Yu Tang, Fengxia Ruan, Zichen Xu, Lei Li, Xia Fu, Daoqin Liu, Aidong Chen, Qiwen Wu

“…Results After adjusting for potential confounders, we observed that each standard deviation (SD) increase in eGDR was associated with a reduced risk of stroke, with an adjusted odds ratio (OR) of 0.746 [95% confidence interval (CI): 0.661–0.842]. …”
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Mechanism model of dynamic polyurethanes with two scales of nodes to regulate mechanical property by Yue Liu, Jinpeng Li, Litong Jia, Manyu Li, Yifan Diao, Zhenqi Han, Chenglei Yu, Tian Liu

“…Dynamic polyurethanes break the boundaries between thermoplastics and thermosets; while realizing reprocessing, their strength is often weakened and uncontrollable, the processing methods are cumbersome and environmentally unfriendly. Herein, we report a molecular topological structure model of polyether-based dynamic polyurethanes with polyphenols for mechanical property regulation; taking pyrogallic acid, polyethylene glycol, and hexamethylene diisocyanate trimer as an example, the elastic modulus ranges from 162.38 to 1038.62 MPa, and the tensile strength ranges from 1.70 to 42.88 MPa,and the tensile elongation can reach up to 47.26 %. …”
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Genetic disruption of Blimp-1 drastically augments the antitumor efficacy of BCMA-targeting CAR T cells by Anthony M. Battram, Joan Mañé-Pujol, David F. Moreno, Aina Oliver-Caldés, Judit Carpio, Oriol Cardus, Luis Gerardo Rodríguez-Lobato, Álvaro Urbano-Ispizua, Carlos Fernández de Larrea

“…To improve long-term efficacy, we used CRISPR/CRISPR-associated protein 9-mediated gene editing to ablate the expression of the transcription factor Blimp-1. …”
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Auxin signaling related to H+-ATPase synthesis and antioxidant enzyme activities regulates fluoranthene uptake by ryegrass roots by Yuanzhou Xu, Yunyun Li, Xinyue Zhang, Zhuoliang Xiao, Jiaguo Jiao, Huijuan Zhang, Huixin Li, Feng Hu, Li Xu

“…However, the molecular mechanisms underlying these behaviors remain unclear. To address this, we exposed ryegrass to different Flu concentrations (0, 5, and 20 mg/L) and conducted a combined transcriptomic and physiological analysis of the root system to elucidate the specific mechanisms of Flu uptake. …”
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Gambaran Perubahan Tekanan Darah Pasca Olahraga Futsal pada Mahasiswa Fakultas Kedokteran Universitas Andalas by Akdri Andi, Afriwardi ., Detty iryani

“…A study has</em><em> </em><em>identified 60 sudden deaths after sports and 58 </em><em>we</em><em>re caused by cardiovascular disorders.…”
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KIT D816V Positive Acute Mast Cell Leukemia Associated with Normal Karyotype Acute Myeloid Leukemia by Marta Lopes, Maria dos Anjos Teixeira, Cláudia Casais, Vanessa Mesquita, Patrícia Seabra, Renata Cabral, José Palla-García, Catarina Lau, João Rodrigues, Maria Jara-Acevedo, Inês Freitas, Jose Ramón Vizcaíno, Jorge Coutinho, Luis Escribano, Alberto Orfao, Margarida Lima

“…Mast cell (MC) leukemia (MCL) is extremely rare. We present a case of MCL diagnosed concomitantly with acute myeloblastic leukemia (AML). …”
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Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma by Olivia W Lee, Danielle M Karyadi, Stephen W Hartley, Weyin Zhou, Mitchell J Machiela, Shahriar A Zamani, Liudmyla Yu Zurnadzhy, John N Weinstein, Young Joo Park, Jeong-Sun Seo, Gerry A Thomas, Tetiana I Bogdanova, Mykola D Tronko, Lindsay M Morton, Stephen J Chanock

“…Since its role in PTC is not fully understood, we conducted a pooled analysis of genomic characteristics and clinical correlates in 1094 primary tumors from four published PTC genomic studies. …”
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Blood pressure categorization and subclinical left ventricular dysfunction in antihypertensive medication‐naive subjects by Koki Nakanishi, Masao Daimon, Yuriko Yoshida, Jumpei Ishiwata, Naoko Sawada, Megumi Hirokawa, Hidehiro Kaneko, Tomoko Nakao, Yoshiko Mizuno, Hiroyuki Morita, Marco R. Di Tullio, Shunichi Homma, Issei Komuro

“…This study investigated the relationship between BP categories given in the new 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline and subclinical LV dysfunction in subjects free of cardiac disease. Methods and results We examined antihypertensive medication‐naive 858 individuals who underwent extensive cardiovascular health check‐up. …”
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The Combination Therapy of Dissolution Using Carbonated Liquid and Endoscopic Procedure for Bezoars: Pragmatical and Clinical Review by Kohei Ogawa, Kenya Kamimura, Ken-ichi Mizuno, Yoko Shinagawa, Yuji Kobayashi, Hiroyuki Abe, Yukari Watanabe, Shunsaku Takahashi, Kazunao Hayashi, Junji Yokoyama, Manabu Takeuchi, Masaaki Kobayashi, Satoshi Yamagiwa, Yuichi Sato, Shuji Terai

“…To develop the safe and effective removal procedure, we carefully reviewed a total of 55 reported cases in this study including our 3 additional cases, successfully treated with dissolution with endoscopic fragmentation. …”
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Psychometric evaluation of the exercise-related cognitive errors questionnaire among Chinese emerging adults by Mengyao Guo, Jin Kuang, Ting Wang, Fabian Herold, Alyx Taylor, Jonathan Leo Ng, Jonathan Leo Ng, M. Mahbub Hossain, M. Mahbub Hossain, Arthur F. Kramer, Arthur F. Kramer, Robert Schinke, Zhihui Cheng, Liye Zou

“…In accordance with the literature, we also observed positive associations between the six dimensions of E-CEQ-C and the constructs of the CD-Quest-C, which provided concurrent validity evidence for the E-CEQ-C.ConclusionThis study showed that E-CEQ-C is a psychometrically sound measure to assess exercise-related cognitive errors in Chinese-speaking populations.…”
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Cystatin C as a Predictor of Mortality and Cardiovascular Events in a Population with Chronic Kidney Disease by Ana Vigil, Emilia Condés, Luis Vigil, Paloma Gallar, Aniana Oliet, Olimpia Ortega, Isabel Rodriguez, Milagros Ortiz, Juan Carlos Herrero, Carmen Mon, Gabriela Cobo, Juana Jimenez

“…Background. We examine whether cystatin C, a surrogate marker of renal function, could identify patients with chronic kidney disease (CKD) with an increased risk of renal disease progression, death, or cardiovascular events. …”
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