Arthroplasty registries at a glance: an initiative of the International Society of Arthroplasty Registries (ISAR) to facilitate access, understanding, and reporting of registry dat... by Anne Lübbeke, Lotje A Hoogervorst, Perla J Marang-van de Mheen, Heather A Prentice, Ola Rolfson, Rob G H H Nelissen, Arnd Steinbrück, Gearoid McGauran, Christophe Barea, Kajsa Erikson, Alma B Pedersen, Martyn Porter

“…Methods: Within the International Society of Arthroplasty Registries (ISAR) we aimed at developing, testing, adopting, and making publicly available a short, standardized registry description with items considered relevant for stakeholders using a cross-sectional study survey. …”
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Identifying health risk determinants and molecular targets in patients with idiopathic pulmonary fibrosis via combined differential and weighted gene co-expression analysis by Abu Tayab Moin, Md. Asad Ullah, Jannatul Ferdous Nipa, Mohammad Sheikh Farider Rahman, Afsana Emran, Md. Minhazul Islam, Swapnil Das, Tawsif Al Arian, Mohammad Mahfuz Enam Elahi, Mukta Akter, Umme Sadea Rahman, Arnab Halder, Shoaib Saikat, Mohammad Jakir Hosen

“…Understanding the molecular mechanisms underlying IPF pathogenesis is crucial for identifying diagnostic markers and therapeutic targets.MethodsWe analyzed transcriptomic data from lung tissues of IPF patients using two independent datasets. …”
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Triiodothyronine activates THRβ to promote PGC1α expression alleviating PQ-induced pulmonary fibrosis by Wenbo Chen, Zhengguang Geng, Haixia Luo, Zhaoyuan Huang, Yufen Yang, Xun Luo, Bao Fu, Zhi Liu, Xiaoyun Fu

“…The aim of this study was to examine whether there was a deficiency of TH in mouse lung tissue after PQ administration, and to explore the effect of T3, and potential mechanisms of action, in alleviation of PQ-induced pulmonary fibrosis. We found that the activity and expression of iodothyronine deiodinase 2 (DIO2), an enzyme that activates TH, were higher in the lungs of patients with pulmonary fibrosis than in controls. …”
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Recent Advances in Fiber-Optic Sensors for the Detection of Inorganic Acidic Gases by Lingnan Kong, Yuanke Gong, Xiaoyu Zhong, Yang Liu, Bo Wan, Quanhua Xie, Yuanyuan He, Xiaoling Peng, Haixing Chang, Dengjie Zhong, Huiling Liu, Nianbing Zhong

“…However, the sensitivity, selectivity, repeatability, and limits of detection of these sensors can be improved to achieve acceptable performance levels for practical applications. In this review, we introduce fiber-optic sensors based on structured optical fibers and fiber gratings for detecting H2S, SO2, NO2, CO2, and N2O. …”
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A SARS‐CoV‐2 EG.5 mRNA vaccine induces a broad‐spectrum immune response in mice by Hongyu Wang, Qinhua Peng, Xinxian Dai, Zhifang Ying, Xiaohong Wu, Xinyu Liu, Hongshan Xu, Jia Li, Leitai Shi, Jingjing Liu, Yunpeng Wang, Danhua Zhao, Yanqiu Huang, Lihong Yang, Ren Yang, Guangzhi Yue, Yue Suo, Qiang Ye, Shouchun Cao, Yuhua Li

“…Therefore, novel COVID‐19 vaccines targeting these emergent variants are needed. We designed and prepared CoV072, an mRNA‐based vaccine against SARS‐CoV‐2 Omicron (EG.5) and other emergent SARS‐CoV‐2 subvariants that encodes the EG.5 spike protein. …”
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Investigating service delivery and perinatal outcomes during the low prevalence first year of COVID-19 in a multiethnic Australian population: a cohort study by Vincent W Lee, N Wah Cheung, Dharmintra Pasupathy, Sarah J Melov, James Elhindi, Therese M McGee, Seng Chai Chua, Justin McNab, Thushari I Alahakoon

“…During the COVID-19 period, we found no change in iatrogenic preterm births (aOR 0.94; 95% CI 0.80 to 1.09) but a 15% reduction in spontaneous preterm birth (aOR 0.85; 95% CI 0.75 to 0.97, p=0.02) and a 10% reduction in SGA infants at birth (aOR 0.90; 95% CI 0.82 to 0.99, p=0.02). …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…Preliminary investigations have shown that decoding motor volition using myoelectric pattern recognition, while providing real-time feedback via virtual and augmented reality (VR-AR), facilitates phantom motor execution (PME) and reduces PLP. Here we present the study protocol for an international (seven countries), multicentre (nine clinics), double-blind, randomised controlled clinical trial to assess the effectiveness of PME in alleviating PLP.Methods and analysis Sixty-seven subjects suffering from PLP in upper or lower limbs are randomly assigned to PME or phantom motor imagery (PMI) interventions. …”
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In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae by Yalin Zhang, Lifang Cui, Ruibing Liu, Zili Feng, Hongjie Feng, Jinglong Zhou, Lihong Zhao, Feng Wei, Heqin Zhu

“…To better understand the mechanisms of this phenomenon, we applied the host selective pressures of resistant and susceptible cotton varieties on V. dahliae strain Vd076 within an artificial cotton Verticillium wilt nursery and greenhouse. …”
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Placental Vascular Malperfusion in Pregnancies With Congenital Heart Disease by Nour Rahnama, MD, Arthur Colson, MD, PhD, Pamela Baldin, MD, PhD, Agnès Pasquet, MD, PhD, Damien Gruson, MD, PhD, David Vancraeynest, MD, PhD, Christophe Beauloye, MD, PhD, Frédéric Debiève, MD, PhD, Sophie Pierard, MD, PhD

“…Methods: In this prospective single-center study, we enrolled pregnant women with CHD who were followed from March 2021 to June 2023, along with a control group matched for age, parity, and body mass index. …”
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The lamprey habenula provides an extreme example for the temporal regulation of asymmetric development by Lucile Guichard, Ronan Lagadec, Léo Michel, Hélène Mayeur, Michaël Fuentès, Jordan Pain, Noah Heier, Quentin Rougemont, Maria Celina Rodicio, Antón Barreiro-Iglesias, Antón Barreiro-Iglesias, Patrick Blader, Michael Schubert, Sylvie Mazan

“…By their phylogenetic position and their marked epithalamic asymmetries, lampreys are relevant models for understanding the formation and evolution of this trait across vertebrates. In this study, we use a transcriptomic approach to identify novel signature markers to characterize the highly asymmetric, bipartite organization of habenulae in lampreys. …”
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Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis by Xiao Han, He Jin, Kuangshi Li, Yanzhe Ning, Lan Jiang, Pei Chen, Hongwei Liu, Yong Zhang, Hua Zhang, Zhongjian Tan, Fangyuan Cui, Yi Ren, Lijun Bai, Yihuai Zou

“…Methods. 26 stroke patients with a right hemispheric subcortical infarct were recruited. We gathered the functional magnetic resonance imaging (fMRI) from patients with stroke and healthy controls in the resting state and after acupuncture intervention, to investigate the instant alterations of the large-scale functional networks. …”
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The diagnostic performance of indocyanine green for the sentinel node biopsy in prostate cancer: A systematic review and meta-analysis by Siyang Ma, Jianxuan Sun, Jinzhou Xu, Ye An, Mengyao Xu, Chenqian Liu, Sihan Zhang, Lintao Miao, Xingyu Zhong, Na Zeng, Haodong He, Shaogang Wang, Qidong Xia

“…., PubMed, EMBASE, Cochrane Library, and Web of Science, to retrieve articles studying the diagnostic performance of ICG for the SNB in PCa from the inception to Sep 9, 2023. We calculated the pooled sensitivity, specificity, likelihood ratios, diagnostic odds ratios and their 95% confidence intervals (CIs). …”
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Prospective study of factors associated with asthma attack recurrence (ATTACK) in children from three Ecuadorian cities during COVID-19: a study protocol by Cristina Ardura-Garcia, Max Bachmann, Alejandro Rodriguez, Philip Cooper, Michael Richard Perkin, Irina Chis Ster, Natalia Cristina Romero, Martha E Chico, Alvaro Cruz, Diana Morillo, Santiago Mena-Bucheli, Angélica Ochoa, Claudia Rodas, Augusto Maldonado, Karen Arteaga, Jessica Alchundia, Karla Solorzano, Camila Figueiredo

“…Asthma attacks are an important cause of emergency care attendance and long-term morbidity. We designed a prospective study, the Asthma Attacks study, to identify factors associated with recurrence of asthma attacks (or exacerbations) among children and adolescents attending emergency care in three Ecuadorian cities.Methods and analysis Prospective cohort study designed to identify risk factors associated with recurrence of asthma attacks in 450 children and adolescents aged 5–17 years attending emergency care in public hospitals in three Ecuadorian cities (Quito, Cuenca and Portoviejo). …”
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Occupational skin diseases among bricklayers and brick masons in a resource poor setting, Southwest Nigeria: prevalence and correlates – a case–control study by Michael Gbenga Israel, Oluwaseyi Kikelomo Israel, Adeolu Oladayo Akinboro, Peter Kehinde Uduagbamen, Sebastien S Oiwoh, Olanrewaju Olayemi, Fatai O Olanrewaju, Mufutau M Oripelaye, Stephen Olawale Aiyedun, Olumayowa Oninla, Olayinka Olasode, Olaniyi Onayemi

“…This can lead to a significant decline in the quality of life and psychosocial function. We determined the prevalence of OSDs and their correlates among bricklayers and brick masons.Design This was a comparative case–control study which involved 200 bricklayers/brick masons and 200 healthy non-bricklayers/non-brick masons.Settings This study was carried out in two local governments (LGAs) in Ogbomoso community.Methods Respondents were selected using a multistage random sampling technique. …”
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Effects of population aging on quality of life and disease burden: a population-based study by Jun-Yan Xi, Bo-Heng Liang, Wang-Jian Zhang, Bo Yan, Hang Dong, Yuan-Yuan Chen, Xiao Lin, Jing Gu, Yuan-Tao Hao

“…Therefore, our study proposed to develop a systematic attribution framework to comprehensively evaluate the health impacts of population aging. Methods We used health-adjusted life expectancy (HALE) to measure quality of life and disability-adjusted life years (DALY) to quantify the burden of disease for the population of Guangzhou. …”
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Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81 by Rehaiem Amel, Bouzouita Abderrazek, Ferjani Sana, Saadi Ahmed, Zrelli Mariem, Kanzari Lamia, Ferjani Asma, Mohamed Riadh Ben Slama, Boutiba Ben Boubaker Ilhem

“…Based on the MICs range of Qs (24–256 mg/L) and FQs (0.24–128 mg/L) breakpoint by EUCAST, we categorized these E. coli isolates into three resistance profiles (I, II, and III) associated with the patterns of chromosomal mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC and the plasmid-mediated quinolone resistance encoding genes (PMQRs) detected by PCR-based assay and sequencing; MICs increase in an escalation step according to the co-occurrence of multiple molecular mechanisms. …”
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Evidence adaptation and tailored implementation of family bereavement support in specialised palliative care: A multi-method study by Myrta Kohler, Qëndresa Thaqi, Silke Kuske, Torsten Schwalbach, Marco Riguzzi, Rahel Naef

“…To close this know-do gap, we undertook an implementation science research project. …”
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Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve by Yuanyuan Li, Ruoyao Xu, Muyan Chen, Kaige Zheng, Huimin Nie, Chengyu Yin, Boyu Liu, Yan Tai, Junying Du, Jie Wang, Jianqiao Fang, Boyi Liu

“…Clinical trials identified beneficial effects of acupuncture on PIPN among patients receiving chemotherapy. Here we explored the mechanisms underlying how acupuncture might alleviate PIPN. …”
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L-Theanine Extends the Lifespan of <i>Caenorhabditis elegans</i> by Reducing the End Products of Advanced Glycosylation by Zhihang Huang, Haiming Jing, Yan Pan, Hongxia Cai, Wenjing Zhang, Jingyuan Zhu, Nan Zhang, Dan Wu, Wentao Xu, Hexiang Qiu, Huihui Bao, Guojun Li, Junyu Ning, Bo Xian, Shan Gao

“…Through an AGE-level analysis, we observed that L-theanine, when administered during early adulthood, notably extended the lifespan of <i>Caenorhabditis elegans</i> under both normal and high-glucose-induced stress conditions. …”
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Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy by Wenwen Wang, Liwei Wu, Jingjing Li, Jie Ji, Kan Chen, Qiang Yu, Sainan Li, Jiao Feng, Tong Liu, Jie Zhang, Jiaojiao Chen, Yuting Zhou, Yuqing Mao, Fan Wang, Weiqi Dai, Xiaoming Fan, Chuanyong Guo, Jianye Wu

“…Oleanolic acid (OA) is a natural compound with antioxidant and anti-inflammatory activity that has been used to treat liver disorders in clinical practice for several years. Here, we investigated the effects and underlying mechanisms of OA in hepatic IRI. …”
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