The Impact of Movement Control Order (MCO) during Pandemic COVID-19 on Local Air Quality in an Urban Area of Klang Valley, Malaysia by Mohd Shahrul Mohd Nadzir, Maggie Chel Gee Ooi, Kemal Maulana Alhasa, Mohd Aftar Abu Bakar, Anis Asma Ahmad Mohtar, Mohd Fadzil Firdzaus Mohd Nor, Mohd Talib Latif, Haris Hafizal Abd Hamid, Sawal Hamid Md Ali, Noratiqah Mohd Ariff, Johary Anuar, Fatimah Ahamad, Azliyana Azhari, Norfazrin Mohd Hanif, Mohammed Ahmed Subhi, Murnira Othman, Mohd Zaim Mohd Nor

“…Nevertheless, data on the effects of MCOs on air quality at local scales are still sparse. Here, we investigate changes in air quality during the MCO at an urban area using the air sensor network AiRBOXSense which measures monoxide (CO) and particulate matter (PM2.5 and PM10). …”
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Comparative Study on Associations Between Lung Cancer Prognosis and Diagnostic Criteria Set by the European Palliative Care Research Collaboration and the Asian Working Group for C... by Utae Katsushima, Takuya Fukushima, Jiro Nakano, Naoya Ogushi, Kazuki Fujii, Yutaro Nagata, Keisuke Kamisako, Yukiko Okuno, Yuta Okazaki, Kentaro Nakanishi, Kiyori Yoshida, Tatsuki Ikoma, Yuki Takeyasu, Yuta Yamanaka, Hiroshige Yoshioka, Kimitaka Hase, Takayasu Kurata

“…Cachexia diagnostic criteria of the European Palliative Care Research Collaboration (EPCRC) may underestimate cachexia in Asians; therefore, new criteria have been proposed by the Asian Working Group for Cachexia (AWGC). We compared both criteria to determine differences in diagnostic rates and their association with lung cancer prognosis. …”
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Representation of Hispanic Patients in Clinical Trials for Respiratory Failure: A Systematic Review by Emily A. Harlan, MD, MA, MSc, Kaitlin Malley, BS, Grecia Quiroga, MD, Eman Mubarak, MD, Pema Lama, BS, Amanda Schutz, PhD, Adolfo Cuevas, PhD, Catherine L. Hough, MD MSc, Theodore J. Iwashyna, MD PhD, Mari Armstrong-Hough, PhD, Thomas S. Valley, MD, MSc

“…Representation of Hispanic patients in clinical trials for respiratory failure is critical to address this inequity. We conducted a systematic review to examine the inclusion of Hispanic patients in randomized controlled trials for AHRF and assessed language as a potential barrier to enrollment. …”
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The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired p... by Huamei Zhou, Xuelei Zhu, Yi Zhang, Wenjuan Xu, Shiqun Li

“…This study aims to spot a routinely tested parameter with discriminative, predictive and prognostic value to enhance CURB-65’s prognostic accuracy in CAP patients with T2DM. Methods We retrospectively studied consecutive CAP patients from 2020 to 2021, comparing laboratory parameters between patients with and without T2DM. …”
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Reimagining habitat suitability modeling for Pacific saury (Cololabis saira) in the Northwest Pacific Ocean through acoustic data analysis from fishing vessels by Minghua Xue, Jianfeng Tong, Wen Ma, Zhenhong Zhu, Weiqi Wang, Shuo Lyu, Xinjun Chen

“…Acoustic data from fishing vessels provide a new option for describing the relative abundance of Pacific saury. We transformed opportunity acoustic data collected from Pacific saury fishing vessel during the summer fishing season of 2021 into an acoustic index that is suitable for habitat modeling. …”
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GC-derived exosomal circMAN1A2 promotes cancer progression and suppresses T-cell antitumour immunity by inhibiting FBXW11-mediated SFPQ degradation by Yikai Shen, Jie Lin, Tianlu Jiang, Xusheng Shen, Ying Li, Yiwang Fu, Penghui Xu, Lang Fang, Zetian Chen, Hongxin Huang, Yiwen Xia, Zekuan Xu, Linjun Wang

“…The molecular mechanism of exosomal circMAN1A2 was investigated via mass spectrometry, immunoprecipitation, Western blot, and single-cell RNA-sequencing data analyses. Results In our study, we determined that circMAN1A2 (hsa_circ_0000118) was enriched in GC-derived exosomes. …”
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Sistem Alarm Penggantian Cairan Infus Berbasis Mikrokontroler menggunakan Wireless by Leila Nurfitria, Susanto Sambasri, Salita Ulitia Prini

“…Abstract Some hospitals that have a larger number of patients than nurse duty so as to cause negligence in controlling causing problems in the organs system due to fluid replacement is done late or even infusion fluid does not drip due to faulty tool, so we created notification system for control hospital infusion fluid using a microcontroller and wireless connected to the nurses room. …”
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Occupational Radiation Exposure during Endoscopic Retrograde Cholangiopancreatography and Usefulness of Radiation Protective Curtains by Tomoyuki Minami, Tamito Sasaki, Masahiro Serikawa, Michihiro Kamigaki, Masanobu Yukutake, Takashi Ishigaki, Yasutaka Ishii, Teruo Mouri, Satoshi Yoshimi, Akinori Shimizu, Tomofumi Tsuboi, Keisuke Kurihara, Yumiko Tatsukawa, Eisuke Miyaki, Kazuaki Chayama

“…To evaluate the effectiveness of radiation protective curtains in reducing the occupational radiation exposure of medical personnel. Methods. We studied medical staff members who had assisted in 80 consecutive therapeutic endoscopic retrograde cholangiopancreatography (ERCP) procedures. …”
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The effect of active and passive smoking during pregnancy on birth outcomes: A cohort study in Shanghai by Xiaokai Wang, Xia Gao, De Chen, Xuelian Chen, Qingwei Li, Jiani Ding, Fangyuan Yu, Xiaoyun Zhu, Nannan Zhang, Yifang Chen

“…This study provides data on the relationship between smoking during pregnancy and delivery outcomes among pregnant women. In the future, we need more effective strategies to protect pregnant women from the harm of tobacco.…”
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Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…Cigarette smoking status was also measured.Results We used weighted regression models to determine the association between ENDS device type current regular use and age group and the association between each ENDS type current regular use and smoking status separately for each age group. …”
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Altered medial temporal lobe subregion volumes in systemic lupus erythematosus patients with neuropsychiatric symptoms by Z. Makdad Najeeb, P. C. Sundgren, A. Jönsen, K. Zervides, J. Lätt, T. Salomonsson, J. Nystedt, P. Nilsson, A. Bengtsson, G. Kuchcinski, L. E. M. Wisse

“…Analyses of Covariance were used to compare MTL subregion volumes between SLE and HI, and between NPSLE and non-NPSLE patients according to three models: the American College of Rheumatology (ACR) model defined by the ACR case definitions for NPSLE (n = 42), the more stringent Systemic Lupus International Collaborating Clinics (SLICC) B model (n = 21), and the most stringent SLICC A model (n = 15). Additionally, we explored the relation between MTL subregion volumes, cognitive functions, and depression scores in SLE patients using partial correlation analyses. …”
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Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer by Juan José Mora Román, Miguel Del Campo, Javiera Villar, Francesca Paolini, Gianfranca Curzio, Aldo Venuti, Lilian Jara, Jorge Ferreira, Paola Murgas, Alvaro Lladser, Augusto Manubens, María Inés Becker

“…Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the treatment of superficial bladder cancer, as carriers/adjuvants of tumor-associated antigens in cancer vaccine development and as adjuvants to dendritic cell-based immunotherapy, because these glycoproteins induce a bias towards Th1 immunity. Here, we analyzed the preclinical therapeutic potential of the traditional keyhole limpet hemocyanin (KLH) and two new hemocyanins from Concholepas concholepas (CCH) and Fissurella latimarginata (FLH) in mouse models of oral squamous cell carcinoma. …”
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Classification of distinct tendinopathy subtypes for precision therapeutics by Chenqi Tang, Zetao Wang, Yuanhao Xie, Yang Fei, Junchao Luo, Canlong Wang, Yue Ying, Peiwen He, Ruojing Yan, Yangwu Chen, Jiayun Huang, Yiwen Xu, Zicheng Wang, Boon Chin Heng, Hengzhi Liu, Jianyou Li, Zi Yin, Haobo Wu, Weishan Chen, Hongwei Ouyang, Xiao Chen, Weiliang Shen

“…The inflammatory proliferative subtype with red appearance (Ir) exhibits the highest levels of upregulated neovascularization and inflammatory pathways, along with severe joint dysfunction. We then established research models, including subtype-specific simulations in animal models and clinical data analysis. …”
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Soil chemical factors contributing to differences in bacterial communities among tea field soils and their relationships with tea quality by Shuning Zhang, Shuning Zhang, Naoki Yanagisawa, Mio Asahina, Hiroto Yamashita, Hiroto Yamashita, Hiroto Yamashita, Takashi Ikka, Takashi Ikka, Takashi Ikka, Takashi Ikka

“…While the relationships between soil bacterial communities and plant nutrient status have been investigated, the specific role by which soil bacterial communities interacted with soil properties to influence tea plant nutrients and quality remained underexplored.MethodsIn this study, different soil types were collected from tea gardens and designated as soil A (pH 3.41), soil B (pH 3.75), soil C (pH 4.16), soil D (pH 4.17) and soil E (pH 5.56) based on the initial soil pH. We conducted pot cultivation of tea plant ‘Yabukita’ to investigate how soil chemical factors affect bacterial communities and their influences on the nutrient status and quality of tea plants, and finally explored the complex relationships between soil bacterial features and tea quality.Results and discussionThe results showed that soil bacterial α-diversity was higher level in soils D and E, with distinct β-diversity patterns separating higher pH soils (D and E) from lower pH soils (A, B, and C). …”
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Development a glycosylated extracellular vesicle-derived miRNA Signature for early detection of esophageal squamous cell carcinoma by Jianlin Chen, Yue Zheng, Zhen Wang, Qi Gao, Kun Hao, Xiongfeng Chen, Nantian Ke, Xiang Lv, Jiamiao Weng, Yuhong Zhong, Zhixin Huang, Miao Fu, Lilan Zhao, Fan Lin, Hui Mi, Haijun Tang, Chundong Yu, Yi Huang

“…Given that glycosylation alterations especially high sialylation and fucosylation, frequently occur during cellular malignant transformation, but their roles are not elucidated. We examined alterations in disease-specific glycosylated extracellular vesicles (EVs)-derived miRNAs in the serum of ESCC patients, evaluating their utility as diagnostic biomarkers. …”
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Critical signals for grassland desertification prediction in the transition zone between desert and typical steppe in InnerMongolia, China by Baoping Meng, Zhuoyan Jin, Jin Chen, Yili Kuang, Shuhua Yi, Yanyan Lv, Jinrong Li

“…In this research, the transition zone between desert and typical steppe in Inner Mongolia, China was studied. We analyzed vegetation patch features (including percentage of landscape (PLAND), patch density (PD), largest patch index (LPI), and perimeter-area ratio distribution (PARA)), species diversity indices (Shannon-Wiener, Simpson, Margalef, Pielou), soil seed bank density, similarity index, and established their relations. …”
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Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A rando... by Vernon Uganiza Rayo, Lauren Okamoto, Maricarmen Cervantes, Mee Young Hong, Nathaniel Jason, Mark Kern, Changqi Liu, Elise North, Svitlana Storm, Oliver C. Witard, Shirin Hooshmand

“…Almonds are a plant-based source of lipids, proteins, fibers, micronutrients, and phytochemicals associated with cardiometabolic health benefits. We examined blood glucose homeostasis, lipid profile, anthropometrics, blood pressure, food cravings, and mood both pre- and post-feeding, using a randomized, crossover design with 26 healthy adults (37±6 y) consuming either ALMOND (57 g/d) or an isocaloric amount of pretzels (CONTROL) for 8 weeks. …”
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The effect of single and dual task training on the intracortical inhibition in young and old adults by Michael Wälchli, Craig Tokuno, Benedikt Lauber, Wolfgang Taube

“…Based on the hypothesis that intracortical inhibition decreases during initial motor learning and increases in later stages, we hypothesize that a training duration of 3 weeks is sufficient to induce positive cortical modulation in young adults but not in older adults. …”
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Fetal cardiac function in pregnancy affected by congenital heart disease: protocol for a multicentre prospective cohort study by Anna Erenbourg, Tracie Barber, Vera Cecotti, Stefano Faiola, Ilaria Fantasia, Tamara Stampaljia, Hagai Avnet, Beata Radzymińska-Chruściel, Neama Meriki, Alec Welsh

“…However, these techniques have not translated from research to clinical settings, due to a lack of standardization and poor repeatability. We seek to evaluate whether application of automated techniques to a cohort with fetal pathology could overcome these factors. …”
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Isolation and Characterization of Human Synovial Fluid-Derived Mesenchymal Stromal Cells from Popliteal Cyst by Fang Li, Jianglin Chen, Mengjia Gong, Yang Bi, Chengchen Hu, Yuanyuan Zhang, Ming Li

“…These results show that we successfully obtained SF-MSCs from the popliteal cyst fluid of pediatric patients, which have the potential to be a valuable source of MSCs.…”
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