Optimizing plant density to improve the soil microenvironment and enhance crop productivity in cotton/cumin intercropping systems by Humei Zhang, Humei Zhang, Liwen Tian, Xianzhe Hao, Nannan Li, Xiaojuan Shi, Feng Shi, Yu Tian, Wenbo Wang, Honghai Luo

“…IntroductionResidual film pollution has become a key factor that affects the sustainable development of cotton, and intercropping may be an economical and environmentally friendly method to reduce the negative effects of nonmulched conditions on cotton growth. We hypothesized that optimizing the cotton/cumin intercropping density would improve the soil environment and increase crop productivity and resource utilization.MethodsTherefore, in this study, singlecropping cotton (CK) was used as the control, and three intercropping cumin seeding densities were used (plants ha-1: 5×105, ID1; 8×105, ID2; and 11×105, ID3). …”
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An Analysis of the Effectiveness and Safety of Upadacitinib in the Treatment of Inflammatory Bowel Disease: A Multicenter Real-World Study by Hongzhen Wu, Tingting Xie, Qiao Yu, Tao Su, Min Zhang, Luying Wu, Xiaoling Wang, Xiang Peng, Min Zhi, Jiayin Yao

“…This study evaluates its real-world effectiveness and safety. <b>Methods:</b> We conducted a multicenter retrospective cohort study in tertiary care centers, involving patients treated with upadacitinib from January 2023 to September 2024. …”
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Wilms tumor primary cultures capture phenotypic heterogeneity and facilitate preclinical screening by Lisa Götz, Jenny Wegert, Alireza Paikari, Silke Appenzeller, Sabrina Bausenwein, Christian Vokuhl, Taryn D. Treger, Jarno Drost, Christin Linderkamp, Dominik T. Schneider, Karen Ernestus, Steven W. Warman, Jörg Fuchs, Nils Welter, Norbert Graf, Sam Behjati, Rhoikos Furtwängler, Manfred Gessler

“…Using three approaches, we have now established a large collection of long-term cultures that represent this diversity. …”
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Identification and functional analysis of a novel SMARCC2 splicing variant in a family with syndromic neurodevelopmental disorder by Ming Li, Jingqi Lin, Hongjun Fei, Jinyu Liu, Yiyao Chen, Xu Han, Yanlin Wang, Jian Wang, Renyi Hua, Shuyuan Li, Niu Li

“…An analysis of genotype-phenotype correlations indicated that our patients displayed neurological phenotypes of greater severity than those observed in patients with truncating variants, instead aligning more closely with the characteristics of the missense/in-frame variant group. Conclusion We identified and reported a pair of twins suffering from syndromic neurodevelopmental disorders caused by a novel splicing variant of SMARCC2. …”
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Effect of cisplatin/gold chitosan nanocomposite on oral squamous cell carcinoma and oral epithelial cells by Basma Abdelrahman Ahmed, Rania Osama M. Mohsen, Marwa Sharaky, Marwa A. Ramadan, Amna H. Faid, Mai Hafez Mohamed

“…Green synthesis of AuNps from eco-friendly agents like chitosan improves the AuNps’ biocompatibility and cytotoxicity. Thus, we synthesized a novel agent of cisplatin coupled to gold chitosan nanoparticles (Cis/AuCh nanocomposite) and examined its effect in addition to the effect of chitosan-reduced gold nanoparticles (AuCh Nps) on (HNO97) OSCC cell line and normal oral epithelial cells (OEC). …”
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Maternal F1 antibodies and cytokines in mother-neonate dog pairs in the Marmota himalayana plague focus by Deming Tang, Asaiti Bukai, Shuai Qin, Ran Duan, Dongyue Lyu, Zhaokai He, Xiaojin Zheng, Weiwei Wu, Junrong Liang, Haifu Qu, Aidai Bieke, Peng Zhang, Dan Zhang, Haonan Han, Qun Duan, Huaiqi Jing, Xin Wang

“…In this study, we investigated the F1 antibody against Yersinia pestis in the sera of mother-neonate shepherd dog pairs in the Marmota himalayana plague focus of the Altun-Qilian Mountains, Qinghai-Tibetan Plateau, China. …”
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Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…Finally, the extract was examined in 3D co-culture model mimicking inflamed obese adipose tissue. We found that C-Akm extract decreased ROS generation, TNF-α and Il-6 gene expression in polarized macrophages, INFγ and IL-17A secretion in LPS-stimulated PBMCs stimulated with LPS. …”
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Země Koruny české a Svatá říše římská v raném novověku by Petr Vorel

“…It was not until the turn of the 17th and 18th centuries, when the Habsburgs' diplomacy strove to enhance its influence among the Electors at the Imperial Diet (which was crowned with success in 1708), that we can see the special-purpose historical interpretation stating that the affiliation of the Bohemian Lands to the Empire had never been interrupted from the Middle Ages and the absence of the King of Bohemia at the Electors' sessions was explained as a consequence of the fact the king also held the office of the emperor. …”
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Robotic Assistance is Associated With No Intraoperative Fluoroscopy or Radiation Exposure During Direct Anterior Total Hip Arthroplasty by Sean Sequeira, MD, Alan Brett, PhD, Joseph Nessler, MD, Benjamin Frye, MD, Michael A. Mont, MD

“…As more surgeons, patients, and surgical staff are exposed to an increasing number of orthopaedic procedures that require ionizing radiation to generate images, such as fluoroscopy and CT, it is important to consider the radiation dosage for all individuals and understand the positives and negatives of each treatment. We must consider the overall long-term health impacts of continuous fluoroscopy vs a one-time CT scan. …”
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The Degree of Cervical Intervertebral Disc Degeneration Is Associated With Denser Bone Quality of the Cervical Sub‐endplate and Vertebral Body by Jia‐Yu Chen, Jia‐Chen Yang, Ruo‐Yao Li, Zu‐Cheng Huang, Zhi‐Ping Huang, Xiu‐Hua Wu, Qing‐An Zhu, Yin Ding

“…This study aims to investigate the relationship between cervical disc degeneration and bone quality of the adjacent vertebral body and sub‐endplate bone with a new MRI‐based bone quality score in patients over 50 years with cervical spondylosis. Methods We retrospectively reviewed 479 cervical disc segments from 131 patients. …”
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Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants by Ritsu Yasuda, Naohisa Yoshida, Takaaki Murakami, Ryohei Hirose, Ken Inoue, Osamu Dohi, Yuji Naito, Yutaka Inada, Takashi Okuda, Daisuke Hasegawa, Kotaro Okuda, Kiyoshi Ogiso, Yoshikazu Inagaki, Koichi Soga, Akira Tomie, Yoshito Itoh

“…In this multicenter study, we analyzed the incidence of POH after EMR associated with DOACs and explored the associated risk factors. …”
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Evaluation of Chitosan Hydrogel for Sustained Delivery of VEGF for Odontogenic Differentiation of Dental Pulp Stem Cells by Si Wu, Yachuan Zhou, Yi Yu, Xin Zhou, Wei Du, Mian Wan, Yi Fan, Xuedong Zhou, Xin Xu, Liwei Zheng

“…Chitosan was widely studied as an effective carrier to deliver bioactive molecules in regenerative medicine. In this study, we conducted a chitosan/β-glycerophosphate (CS/β-GP) hydrogel as a VEGF-sustained release system and explored its effects on dental pulp stem cells (DPSCs). …”
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Clinical Features of COVID‐19 Associated Pulmonary Aspergillosis: A Multicenter, Retrospective Study by Yasheng Zhan, Guojun He, Cheng Zhong, Yake Yao, Jiangying Zhou, Tong Li, Hua Zhou

“…Methods In this study, we conducted a multicenter retrospective survey, which included patients with COVID‐19 from five hospitals in Zhejiang, China. …”
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Gut Dysbiosis and Abnormal Bile Acid Metabolism in Colitis-Associated Cancer by Li Liu, Min Yang, Wenxiao Dong, Tianyu Liu, Xueli Song, Yu Gu, Sinan Wang, Yi Liu, Zaripa Abla, Xiaoming Qiao, Wentian Liu, Kui Jiang, Bangmao Wang, Jie Zhang, Hailong Cao

“…Studies have shown the association between gut dysbiosis, abnormal bile acid metabolism, and inflammation process. Here, we aimed to investigate these two factors in the CAC model. …”
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TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells by Yijia Zhou, Yuandong Liao, Chunyu Zhang, Junxiu Liu, Wei Wang, Jiaming Huang, Qiqiao Du, Tianyu Liu, Qiaojian Zou, Hua Huang, Pan Liu, Shiyin Ooi, Run Chen, Meng Xia, Hongye Jiang, Manman Xu, Yuwen Pan, Shuzhong Yao

“…However, the specific mechanisms involved in regulating cell functions remain largely unknown. Here, we analyzed published data from public databases and our global transcriptome data, thus identifying cancer-related signaling pathways and molecules. …”
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Effects of Different Light Spectra on Oxidative Stress and Nutritional Quality of the Fish <i>Plectropomus leopardus</i> by Wensheng Li, Zheng Zhang, Baoliang Liu, Yingying Fang, Shuquan Cao, Wenyang Li, Yan Sun, Chengbin He, Chuanxin Zhang, Fan Fei

“…After experimentation, blood and muscle tissue were collected and analyzed for biochemical variables and nutritional quality. We demonstrated that the total cholesterol, triglycerides activities of <i>P. leopardus</i> in the dark groups were substantially elevated, relative to other groups (<i>p</i> < 0.05). …”
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Preconception diet quality and modified natural cycle in vitro fertilisation outcomes by Janine P.M. Faessen, Irene Homminga, Marion E.C. Buso, Ruxandra A. Nagy, Jannie van Echten-Arends, Edith J.M. Feskens, Uwe J.F. Tietge, Annemieke Hoek, Elske M. Brouwer-Brolsma

“…Lifestyle has been associated with in vitro fertilisation (IVF) success rates, but studies on diet and IVF outcomes are inconclusive. We studied associations between adherence to the Dutch guidelines for a Healthy diet 2015 and pregnancy chances among women receiving modified natural cycle in vitro fertilisation (MNC-IVF). …”
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Delirium and Cognitive Screening in National Hip Fracture Registries: Scoping Review Protocol [version 2; peer review: 2 approved] by Pamela Hickey, Rose S. Penfold, Louise Brent, Niamh A. Merriman, Eithne Sexton, Tara Coughlan, Mary E. Walsh, Antony Johansen, Catherine Blake, Alasdair M. J. MacLullich, Andrew J. Hall, Cristina Ojeda-Thies

“…Methods This scoping review will be conducted in accordance with the Preferred Reporting Items for Systematic Reviews extension for Scoping Reviews (PRISMA-ScR). We will search the following databases: Medline Ovid; Embase; CINAHL EBSCOHost. …”
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Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn by Helena Miriam Lorenzo Juanes, Amparo López-Bernus, Belen Vicente, Montserrat Alonso-Sardón, Beatriz Rodríguez Alonso, Josue Pendones Ulerio, Pedro Fernandez Soto, Juan Luis Muñoz Bellido, Antonio Muro, Moncef Belhassen-García

“…Patients were retrospectively recruited from 2005 to 2023. Principal findings: We screened 485 serum samples, with a mean (±SD) age of 17 years (±9.9). …”
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NRF2 Antioxidant Response and Interferon‐Stimulated Genes Are Differentially Expressed in SARS‐CoV‐2‐Positive Young Subjects by Walter Toscanelli, Matteo Fracella, Marta De Angelis, Carolina Scagnolari, Leonardo Sorrentino, Elena Piselli, Maria Elena Marcocci, Fabio Midulla, Enrica Mancino, Raffaella Nenna, Laura Petrarca, Anna Teresa Palamara, Guido Antonelli, Alessandra Pierangeli, Lucia Nencioni

“…The results were correlated with Types I and III IFN genes and IFN‐stimulated genes (ISGs). Results We found that NRF2 expression was markedly diminished in positive patients compared to negative. …”
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