DsTau: study of tau neutrino production with 400 GeV protons from the CERN-SPS by The DsTau collaboration, Shigeki Aoki, Akitaka Ariga, Tomoko Ariga, Sergey Dmitrievsky, Elena Firu, Dean Forshaw, Tsutomu Fukuda, Yuri Gornushkin, Ali Murat Guler, Maria Haiduc, Koichi Kodama, Masahiro Komatsu, Muhtesem Akif Korkmaz, Umut Kose, Madalina Miloi, Antonio Miucci, Motoaki Miyanishi, Mitsuhiro Nakamura, Toshiyuki Nakano, Alina Neagu, Hiroki Rokujo, Osamu Sato, Elizaveta Sitnikova, Yosuke Suzuki, Tomoki Takao, Svetlana Vasina, Mykhailo Vladymyrov, Thomas Weston, Junya Yoshida, Masahiro Yoshimoto

“…The experimental method is based on a use of high resolution emulsion detectors for effective registration of events with short lived particle decays. Here we present the motivation of the study, details of the experimental technique, and the first results of the analysis of the data collected during test runs, which prove feasibility of the full scale study of the process in future.…”
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Clinical and Onychoscopy Patterns in Fingernail Onychomycosis—A Study by the International Dermoscopy Society Trichoscopy And Onychoscopy Task Force by Matilde Iorizzo, Bianca Maria Piraccini, Aurora Alessandrini, Francesca Bruni, Laura Vollono, Francesca Pampaloni, Nilton Gioia Di Chiacchio, Nilton Di Chiacchio, Juan Jimenez-Cahue, Chander Grover, Zoe Apalla, Asmahne Souissi, Awatef Kelati, Eirini Kyrmanidou, Elizabeth Lazaridou, Michela Starace

“…Fingernail onychomycosis is significantly less frequent than toenail onychomycosis and it is often misdiagnosed due to its subtle clinical presentations. Objectives: We sought to analyze the clinical and onychoscopic features of culture-proven cases of fingernail onychomycosis in adult and pediatric patients. …”
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Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment by Sulai Liu, Xinyu Liu, Xuepeng Li, Ou Li, Weimin Yi, Junaid Khan, Pingzhou Yang, Chao Guo, Chuang Peng, Bo Jiang

“…Surgery was successfully completed in 6 patients. We found that the tumor size of 6 patients ranged from 1.5 to 3.6 cm, with 4 lymph nodes. …”
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Metabolomic Profiling Reveals Potential Biomarkers and Prominent Features in HIV/AIDS Patients Co-Infected with SARS-CoV-2 by Xuan Yan, Xinyu Zhang, Wei Song, Tangkai Qi, Zhenyan Wang, Yang Tang, Jianjun Sun, Shuibao Xu, Junyang Yang, Jiangrong Wang, Jun Chen, Renfang Zhang, Li Liu, Yinzhong Shen

“…In this study, the aim is to analyze the metabolomic profiles of HIV/AIDS patients co-infected with SARS-CoV-2 and to identify biomarkers indicative of co-infection. In this study, we conducted a retrospective cohort analysis of peripheral blood samples collected from 30 HIV/AIDS patients co-infected with SARS-CoV-2 (pc group) and 30 patients without SARS-CoV-2 (nc group). …”
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Dynamic mechanical response and deformation-induced co-axial nanocrystalline grains facilitating crack formation in magnesium-yttrium alloy by Shuang Yang, Fei Liu, Fei Chen, Yuan-Biao Tan, Hao Fu, Si-Yuan Wei, Song Xiang

“…Contrary to crack initiation mechanism facilitated by adiabatic shear bands, we find that high-density co-axial nanocrystalline grains form near cracks, which leads to local softening and promotes crack initiation and rapid propagation. …”
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Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor by Toru Momozane, Eriko Fukui, Soichiro Funaki, Makoto Fujii, Yuhei Kinehara, Emiko Ito, Shigeru Miyagawa, Yuko Ohno, Yoshiki Sawa, Meinoshin Okumura, Yasushi Shintani

“…However, differentiation efficiency varies among reports and improvements are needed. In the present paper, we propose a novel method for elimination of residual undifferentiated murine iPSCs using JQ1, a potent inhibitor of bromodomain (BRD) and extraterminal domain (BET) family proteins, for efficient differentiation into ATII. …”
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Predictors and Prognostic Effects of Perioperative Myocardial Injury After Transcatheter Aortic Valve Replacement According to VARC-3 Criteria by Hu X, Zhao Z, Wang C, Feng D, Chen Y, Niu G, Zhou Z, Zhang H, Li Z, Ye Y, Wang M, Wu Y

“…PPMI was defined according to the VARC-3 criteria as a 70-fold increase of upper reference limit in cardiac troponin I (cTnI) levels. We compared the baseline characteristics, perioperative conditions, and in-hospital and long-term endpoints between the PPMI and non-PPMI groups. …”
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A Multicenter Observational Prospective Cohort Study of Association of the Prehospital National Early Warning Score 2 and Hospital Triage with Early Mortality by Francisco Martín-Rodríguez, Raúl López-Izquierdo, Carlos del Pozo Vegas, Juan F. Delgado-Benito, Carmen del Pozo Pérez, Virginia Carbajosa Rodríguez, Agustín Mayo Iscar, José Luis Martín-Conty, Carlos Escudero Cuadrillero, Miguel A. Castro-Villamor

“…This is a multicenter longitudinal observational cohort study on patients attending Advanced Life Support units and transferred to the emergency department of their reference hospital. We collected demographic, physiological, and clinical variables, main diagnosis, and hospital triage level as well as mortality. …”
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Interferon Treatment of Hepatitis C Reinfection after Liver Transplantation: A Meta-Analysis by Yaqin Chen, Gang Wu, Hongmin Zhang, Hua Xu, Hong Li, Ling Chen, Yixuan Yang, Peng Hu, Dazhi Zhang, Hong Ren, Huaidong Hu

“…This meta-analysis was performed to compare the effectiveness and risk of adverse events of interferon-based therapy with no treatment after liver transplantation. Methods. We searched electronic databases up to July 31, 2013, to obtain relevant research reports that satisfied the inclusion criteria. …”
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Network Meta-Analysis and Trial Sequential Analysis of Randomised Controlled Trials Comparing Robotic, Laparoscopic, and Open Pancreatoduodenectomy by Nejo Joseph, MBChB, Chris Varghese, MBChB, James Lucocq, MBChB, Matthew J. McGuinness, MBChB, Samuel Tingle, MBChB, Giovanni Marchegiani, PhD, Kjetil Soreide, PhD, Mohammed Abu-Hilal, Jas Samra, Marc Besselink, PhD, Steve White, Sanjay Pandanaboyana, FRCS

“…With recent randomised controlled trials (RCTs) comparing open pancreatoduodenectomy (OPD) with robotic or laparoscopic pancreatoduodenectomy (RPD or LPD), we undertook a network meta-analysis (NMA) comparing all 3 approaches to evaluate comparative outcomes. …”
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Positive Antithyroid Antibodies and Nonsuppressed TSH Are Associated with Thyroid Cancer: A Retrospective Cross-Sectional Study by Jan Krátký, Jana Ježková, Mikuláš Kosák, Hana Vítková, Jana Bartáková, Miloš Mráz, Jindřich Lukáš, Zdenka Límanová, Jan Jiskra

“…The aim of our study was to compare the presence of HT and thyroid function in patients with TC and benign nodules. We analyzed 2571 patients after fine needle aspiration biopsy of thyroid nodule. …”
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Rabies vaccinations at the rural–urban divide: successes and barriers to dog rabies vaccination programs from a rural and urban campaign in Zambia by Ricky Chazya, Chilufya Aneta Susan Mulenga, Andrew D. Gibson, Frederic Lohr, Cassandra Boutelle, Sarah Bonaparte, Oline Sinywibulula, Gareth Thomas, Patricia Bwalya, George Dautu, Linous Munsimbwe, Geoffrey Muuka, Luke Gamble, Ryan M. Wallace, Michelle A. Waltenburg

“…Traditional vaccination approaches in Zambia rarely collect operational data to assess coverage and inform subsequent campaigns.MethodsFollowing mass vaccination campaigns in rural (Itezhi tezhi) and urban (Lusaka) communities, we evaluated vaccination coverage achieved during the campaigns and characterized and estimated the dog population in these communities.ResultsHerd immunity (i.e., 70% vaccination coverage) was not achieved in the Lusaka campaign, likely due to challenges in pre-campaign community sensitization and distance to vaccination sites in the central point campaign approach. …”
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Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal) by Nuwadatta Subedi, Sunita Ranabhat, Sanjib Mani Regmi, Mukesh Mallik, Dela Singh, Shree Krishna Shrestha, Bandana Gurung, Arjun Bhattarai, Madan Prasad Baral, Sudhir Raman Parajuli, Ramchandra Bastola, Junu Shrestha, Sahisnuta Basnet, Eva Gauchan, Sabita Paudel

“…Methods The study will be conducted among the perinatal deaths reported in the five hospitals implementing the Maternal and Perinatal Death Surveillance and Response (MPDSR) system in Kaski district of Nepal. We will also conduct verbal autopsy (VA) among community perinatal deaths reported in the district. …”
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Azole Resistance and <i>ERG11</i> Mutation in Clinical Isolates of <i>Candida tropicalis</i> by Adriele Celine Siqueira, Gisele Aparecida Bernardi, Lavinia Nery Villa Stangler Arend, Gabrielle Tomé Cordeiro, Daiane Rosolen, Fernanda Costa Brandão Berti, Amanda Maria Martins Ferreira, Thaís Muniz Vasconcelos, Bianca Cruz Neves, Luiza Souza Rodrigues, Libera Maria Dalla-Costa

“…We investigated the molecular mechanisms underlying azole resistance in seven <i>Candida tropicalis</i> isolates that caused candidemia and candiduria in Paraná, Brazil (2016–2022). …”
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The Mechanisms of the Regulation of Immune Response in Patients with Comorbidity of Chronic Obstructive Pulmonary Disease and Asthma by Elena P. Kalinina, Yulia K. Denisenko, Tatyana I. Vitkina, Elena G. Lobanova, Tatyana P. Novgorodtseva, Marina V. Antonyuk, Tatyana A. Gvozdenko, Vera V. Knyshova, Anna V. Nazarenko

“…To study the features of the regulation of immune response in patients with comorbid COPD and asthma. Methods. We assessed the levels of CD3+, CD4+, CD8+, CD4+/CD8+, CD19+, CD25+, HLA-DR, total IgE, TNF-α, IL-4, IFN-γ, TXB2, and LTB4 in patients with comorbid COPD and asthma. …”
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Involving national stakeholders in a systems approach to map drivers of childhood obesity and actions to prevent childhood obesity in Denmark: the Generation Healthy Kids Study by Knud Ryom, Paul Bloch, Ulla Toft, Didde Høeg, Louise T. Thomsen, Steven Allender, Harry Rutter, Adrian Bauman, Rikke Fredenslund Krølner, Anders Blædel Gottlieb Hansen

“…Methods During two workshops in the autumn of 2022, national stakeholders (n = 45) were involved in generating and revising a system map. We used a scripted approach inspired by group model building and community-based systems dynamics methods to engage stakeholders, collect and visualize their knowledge on childhood obesity, create consensus on the drivers of childhood health, identify local and national intervention opportunities for prevention of childhood obesity and develop actions to create system changes. …”
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Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes by Jaroslaw Szczyrba, Volker Jung, Michaela Beitzinger, Elke Nolte, Sven Wach, Martin Hart, Sandra Sapich, Marc Wiesehöfer, Helge Taubert, Gunther Wennemuth, Norbert Eichner, Thomas Stempfl, Bernd Wullich, Gunter Meister, Friedrich A. Grässer

“…Novel potential targets were analyzed by luciferase assays with miRNAs known to be deregulated in PCa. We demonstrate that the mRNAs of the death effector domain-containing protein (DEDD), the tumor necrosis factor receptor superfamily, member 10b protein (TNFRSF10B), the tumor protein p53 inducible nuclear protein 1 (TP53INP1), and the secreted protein, acidic, cysteine-rich (SPARC; osteonectin) are regulated by miRNAs miR-148a, miR-20a, miR-24, and miR-29a/b, respectively. …”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies by Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol

“…This genus of plants is used for anti-inflammatory, antioxidant, and antimicrobial activities. In this study, we aimed to evaluate the anthelmintic activities of <i>Nepeta racemosa</i> Lam. …”
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Sport values and sustainability? by Tess Kate Schweizer, Nicolas Margas

“…Methods Following PRISMA guidelines, we conducted a systematic review through Google Scholar, Semantic Scholar, and ERIC database using values of sport, sport values, sporting values, and athletic values keywords (n=7992). 32 studies published between 1990 and 2023 were retained. …”
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Recombinant Enolase of Trypanosoma cruzi as a Novel Vaccine Candidate against Chagas Disease in a Mouse Model of Acute Infection by Minerva Arce-Fonseca, María Cristina González-Vázquez, Olivia Rodríguez-Morales, Verónica Graullera-Rivera, Alberto Aranda-Fraustro, Pedro A. Reyes, Alejandro Carabarin-Lima, José Luis Rosales-Encina

“…Two drugs exist for the treatment of Chagas disease, nifurtimox and benznidazole; they are only effective in the acute phase, and a vaccine is currently not available. In this study, we used the recombinant enolase from T. cruzi H8 strain (MHOM/MX/1992/H8 Yucatán) (rTcENO) and its encoding DNA (pBKTcENO) to immunize mice and evaluate their protective effects in an experimental murine model of acute phase infection. …”
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