Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer by Wang S, Ma C, Ren Z, Zhang Y, Hao K, Liu C, Xu L, He S, Zhang J

“…The diagnostic model was evaluated in an independent validation cohort (n=139).Results: We developed a diagnostic model for GC based on five miRNA pairs. …”
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DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells by Maria Cristina Grimaldi, Sara Bozzer, Dick J. Sjöström, Dick J. Sjöström, Linnea I. Andersson, Tom Eirik Mollnes, Tom Eirik Mollnes, Per H. Nilsson, Per H. Nilsson, Luca De Maso, Federico Riccardi, Michele Dal Bo, Daniele Sblattero, Paolo Macor

“…However, the nanoplatform must guarantee both the local production of the protein and the safety of the treatment to allow an effective therapy with reduced systemic toxicity.MethodsIn order to ensure a selective delivery of nucleic acids, we developed poly(lactic-co-glycolic acid) (PLGA)-poly(vinyl alcohol) (PVA) NPs loaded with an Enhanced Green Fluorescent Protein (EGFP)-coding plasmid and covalently coated with antiCD19 recombinant antibody as a targeting mechanism. …”
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A Review of Marine Bacterial Intracellular and Extracellular Bioactive Compounds as Novel Antibacterial and Anti-Inflammation Agents by Harningsih Karim, Arief Azis, Ananda Ramadani, Anita Anita, Ahyar Ahmad, Hasnah Natsir, Paulina Taba, Suriati Eka Putri, Sarlan Sarlan, Siti Halimah Larekeng, Rizal Irfandi

“…This review summarizes several bacterial intracellular and extracellular bioactive compounds that have been applied as antibacterial and anti-inflammatory agents in 2016–2024, which we present in the form of structures, species sources, and evaluations of these compounds' antibacterial and anti-inflammatory activities. …”
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Antiganglioside Antibodies and Inflammatory Response in Cutaneous Melanoma by Corina Daniela Ene, Mircea Tampa, Ilinca Nicolae, Cristina Iulia Mitran, Madalina Irina Mitran, Clara Matei, Ana Caruntu, Constantin Caruntu, Simona Roxana Georgescu

“…The aim of the study was to characterize the relation between antiganglioside antibodies and inflammation in cutaneous melanoma focusing on gangliosides GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b. Material and Method. We performed an observational study that included 380 subjects subdivided into three groups: patients with metastatic melanoma (170 cases), patients with primary melanoma (160 cases), and healthy subjects (50 subjects). …”
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Effect of Daily Fiber Intake Among Cirrhotic Patients With and Without Portosystemic Shunts by Simona Parisse, Sara Carnevale, Elio Damato, Flaminia Ferri, Monica Mischitelli, Mario Corona, Pierleone Lucatelli, Alfredo Cantafora, Adriano De Santis, Domenico Alvaro, Maurizio Muscaritoli, Stefano Ginanni Corradini

“…By adjusting for confounders in logistic regression models we found that improvement in MELD over time was inversely associated with insoluble fiber consumption expressed in milligrams per kilogram (mg/kg) body weight in CIRs without PSs [odds ratio (OR): 0.968; 95% confidence interval (CI): 0.939, 0.997; P = 0.005] but with soluble fiber consumption in CIRs with PSs [OR: 0.946; 95% CI: 0.912, 0.982; P = 0.001]. …”
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Lidar estimates of birch pollen number, mass, and CCN-related concentrations by M. Filioglou, P. Tiitta, P. Tiitta, X. Shang, A. Leskinen, P. Ahola, S. Pätsi, A. Saarto, V. Vakkari, V. Vakkari, U. Isopahkala, M. Komppula

“…Lidar remote sensing of pollen is an emerging research field, and in this study, we present for the first time retrievals of particle number, mass, CCN, giant CCN (GCCN), and ultragiant CCN (UGCCN) concentration estimations of birch pollen derived from polarization lidar observations and specifically from a PollyXT lidar and a Vaisala CL61 ceilometer at 532 and 910 nm, respectively.…”
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The Effectiveness of pen‒culture construction for cultivation of sea cucumber by Pitjont Tomatala, Petrus Paulus Letsoin, Evangelin Martha Yulia Kadmaer

“…The result of visual observation showed that conventional pen‒culture treatment A was more quickly damaged and it was more damaged compared to engineered pen-culture treatment B.Through t‒test we got T count (1.065) < Ttable (6.313) for survival and T count (0.084) < Ttable (1.782) for growth. …”
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FoodMicroDB: A microbiome database for composition and time‐series research in food by Yahui Li, Hujie Lyu, Haifei Yang, Zhicheng Ju, Chuang Ma, Huiyu Hou, Yao Wang, Yuanping Zhou, Yunyun Gao, Junbo Yang, Shanshan Xu, Defeng Bai, Hao Luo, Salsabeel Yousuf, Tianyuan Zhang, Jiani Xun, Meiyin Zeng, Heyuan Qi, Tong Chen, Yong‐Xin Liu

“…However, there is a notable lack of databases specialized for this field. To address this gap, we developed Food Microbiome Database (FoodMicroDB), a platform aimed at enhancing the reusability and accessibility of food microbiome data through comprehensive data management and data visualization tools. …”
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Using peer narrative support to promote return to work for cancer survivors: a protocol study of action research by Wenqian Que, Xiaoyun Hu, Tingting Wu, Haiyin Zhang, Yue Shi, Jingyi Zhao, Xiaoqin Su, Benxin Kuai, Yujie Guo

“…High-quality narrative support can help both parties gain positive meaning in communication. Therefore, we draw on narrative-related theoretical techniques to construct a model of peer narrative support to facilitate cancer survivors’ return to work. …”
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Introducing a Coopetition Model for Domestic Airlines in Iran by Saedeh Ghayourisales, Mohsen Nazari, Mohammadali Shahhoseini

“…After conducting interviews with the 11th expert, we reached theoretical saturation, but for more certainty, the 12th expert was also interviewed. …”
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Genome drafting of nosocomial infection CRE Klebsiella pneumoniae confirming resistance to colistin and eravacycline, carrying blaNDM-1, mcr-1, and blaKPC-2, in neonatology from No... by Xinlong Zhou, Kailash Wagh, Guizhen Lv, Devender Sharma, Wei Lei

“…BackgroundCarbapenem-resistant Klebsiella pneumoniae (CRKP) is a critical pathogen in healthcare settings, associated with high mortality due to its extensive antibiotic resistance. In this study, we report an outbreak of CRKP in a neonatal intensive care unit (NICU) within a 200-bed tertiary hospital. …”
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Search for Neutrino Signals Correlated with LHAASO Diffuse Galactic Emission by Wenlian Li, Tian-Qi Huang, Donglian Xu, Huihai He

“…Using 7 yr of publicly available IceCube track data with the full detector, we conduct a template search using the γ -ray flux map observed by LHAASO-KM2A as the neutrino emission template and perform a scan search of the Galactic plane. …”
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Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality by Yao Huang, Yao Huang, Weili An, Weili An, Tianzhu Ning, Zhiguang Ma, Yuelin Li, Ke Liu, Lingbo Ji, Lingbo Ji, Hongxiao Liu, Dafeng Hui, Hai Ren

“…., rhizosphere, rhizoplane, and endosphere) and their impact on water purification is still limited.MethodsTo address this knowledge gap, we employed high-resolution 16S rRNA deep amplicon sequencing to explore the bacterial community structure and assembly within the root components of three plant species (i.e. …”
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Effect of Sodium Azide on Quantitative and Qualitative Stem Traits in the M2 Generation of Ethiopian Sesame (Sesamum indicum L.) Genotypes by Micheale Yifter Weldemichael, Yemane Tsehaye Baryatsion, Desta Berhe Sbhatu, Girmay Gebresamuel Abraha, Hagos Mohammedseid Juhar, Abraha Birhan Kassa, Fiseha Baraki Sibhatu, Hailay Mehari Gebremedhn, Tesfakiros Semere Gebrelibanos, Mohammed Mebrahtu Mossa, Mullubrhan Mekonen Gebru, Birhanu Kahsay Meresa, Medhin Teklay, Birhanu Debesay Berhe, Haftay Abadi Gebru

“…All the fourteen genotypes (both treated and control) were clustered into four groups. In conclusion, we observed a highly significant variation among the genotypes due the effect of the chemical and genotypes themselves. …”
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Predictive Value of NT-proBNP for Functional Outcome of Ischemic Stroke Without Cardiac Disease: A Prospective, Observational Study by Liu R, Chen G, Zhao N, Yue W

“…Ran Liu,1 Guojuan Chen,2 Na Zhao,1 Wei Yue1 1Department of Neurology, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin Huanhu Hospital, Tianjin, 300350, People’s Republic of China; 2Department of Neurology, Tangshan Gongren Hospital, Tangshan, People’s Republic of ChinaCorrespondence: Wei Yue, Department of Neurology, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin Huanhu Hospital, No. 6 Jizhao Road, Shuanggang Town, Jinnan District, Tianjin, 300350, People’s Republic of China, Email hhyuewei2021@163.comPurpose: Our study aimed to evaluate the prognostic value of NT-proBNP in predicting adverse outcomes among patients with anterior circulation infarction (ACI) and posterior circulation infarction (PCI), specifically in those without pre-existing cardiac comorbidities.Patients and Methods: This single-center, prospective observational study enrolled patients with acute ischemic stroke (AIS) within 7 days of symptom onset. We aimed to elucidate predictive role of NT-proBNP levels in determining adverse outcomes in AIS patients. …”
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Using Statistical Analysis to Assess Urban Groundwater in Beni Mellal City (Morocco) by Mohamed El Baghdadi, Radouane Medah, Amal Jouider

“…Samples in cluster C3 have more content of heavy metal (Cd, Fe, Mn, and Ni), CE, TDS, Ca, Mg, Na, HCO3, NO3, and Cl, with low content of Cr and Al and medium values of K and SO4. We recommended the monitoring and follow-up of the water quality under the city and the repair of pipes especially in the downtown area to limit unwanted infiltration. …”
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Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013–2015) by Won Kyoung Cho, Hyo-Kyoung Nam, Jae Hyun Kim, Young-Jun Rhie, Sochung Chung, Kee-Hyoung Lee, Byung-Kyu Suh

“…Purpose. In this study, we investigated the status of thyroid function and its association with metabolic risk factors in Korean adolescents. …”
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DeepCERES: A deep learning method for cerebellar lobule segmentation using ultra-high resolution multimodal MRI by Sergio Morell-Ortega, Marina Ruiz-Perez, Marien Gadea, Roberto Vivo-Hernando, Gregorio Rubio, Fernando Aparici, Maria de la Iglesia-Vaya, Gwenaelle Catheline, Boris Mansencal, Pierrick Coupé, José V. Manjón

“…Notably, our approach deviates from the traditional U-Net model by exploring alternative architectures. We have also integrated deep learning with classical machine learning methods incorporating a priori knowledge from multi-atlas segmentation which improved precision and robustness. …”
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Novel indicator of microvascular complications in patients with type 2 diabetes mellitus and shortened erythrocyte lifespan: a multicenter cross-sectional analysis by Yunqi Wu, Binshan Zhang, Xin Ma, Pei Yu, Saijun Zhou, Xinli Wang

“…Abstract Introduction In this study, we assessed whether the ratio of glucose management index (GMI) to glycated albumin (GA) was linked to microvascular complications in patients with type 2 diabetes mellitus (T2DM) who also possessed a shortened erythrocyte lifespan. …”
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Non-communicable diseases and their associations with outpatient services utilisation: insight from a population-based survey in Malaysia by Jabrullah Ab Hamid, Awatef Amer Nordin, Suhana Jawahir, Adilius Manual, Iqbal Ab Rahim, Sarah Nurain Mohd Noh, Nur Elina Ab Mutalib, Nurul Salwana Abu Bakar

“…Characteristics of respondents and those having multimorbidity were described using complex sample descriptive statistics. We used multivariable logistic regression to determine the associated factors of having multimorbidity and the association between the number of non-communicable diseases and outpatient services utilisation.Results Overall, 11 347 respondents were included in the analysis. …”
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