Random resistive memory-based deep extreme point learning machine for unified visual processing by Shaocong Wang, Yizhao Gao, Yi Li, Woyu Zhang, Yifei Yu, Bo Wang, Ning Lin, Hegan Chen, Yue Zhang, Yang Jiang, Dingchen Wang, Jia Chen, Peng Dai, Hao Jiang, Peng Lin, Xumeng Zhang, Xiaojuan Qi, Xiaoxin Xu, Hayden So, Zhongrui Wang, Dashan Shang, Qi Liu, Kwang-Ting Cheng, Ming Liu

“…The computational demands of training ever-growing models further exacerbate these challenges. We propose a hardware-software co-designed random resistive memory-based deep extreme point learning machine. …”
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Detection of genetic sex using a qPCR-based method in the bigfin reef squid (Sepioteuthis lessoniana) by Yi-Chien Lee, Li-Lun Tang, Yu-Chen Yeh, Hau-Wen Li, Huei-Mien Ke, Cheng-Ju Yang, Chun-I Chiang, Chia-Hui Wang, Yung-Che Tseng, Ching-Fong Chang, Isheng Jason Tsai, Guan-Chung Wu

“…Analysis of the female and male genome coverage along the assembly confirms a ZZ/Z0 female hemizygous sex-determination system in bigfin reef squid. We identified Z chromosome linked regions and developed a quantitative PCR (qPCR)-based method to measure the copy number variance of these Z-specific regions, normalized by autosomal regions, with ratios of 1:0.5 in ZZ males and Z0 females, respectively. …”
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Endophytic Fungi of <i>Calea pinnatifida</i> (Asteraceae): Dereplication of Crude Extracts, Antimicrobial Properties, and Identification of New Tetronic Acid Derivative Produced by... by Bianca Barna, Lhaís Araújo Caldas, Jackson Monteiro, Augusto Leonardo dos Santos, Renata Castiglioni Pascon, Marcelo Afonso Vallim, Marcelo José Pena Ferreira, Sarah Santos Gonçalves, Glaucia Queiroz dos Santos, Anderson Messias Rodrigues, Jamile Ambrósio de Carvalho, Suzan Pantaroto de Vasconcellos, Patricia Sartorelli

“…Endophytic fungi are increasingly being recognized for their diverse metabolites that may exhibit antimicrobial properties. In our study, we isolated seven endophytic fungal strains from <i>Calea pinnatifida</i>, which were identified as <i>Hypomontagnella barbarensis</i>, <i>Neopestalotiopsis clavispora</i>, <i>Nigrospora sacchari-officinarum</i>, <i>Annulohypoxylon moriforme</i>, <i>Colletotrichum siamense</i>, and <i>Colletotrichum karstii</i> (with two isolates from the same species). …”
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Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a p... by Ziyu Weng, Chenzhong Wang, Bo Liu, Yi Yang, Yueqi Zhang, Chi Zhang

“…Results In this study, we identified three hub genes: interleukin 1 receptor-associated kinase 3 (IRAK3), integrin subunit beta-like 1 (ITGBL1), and Ras homolog family member U (RHOU). …”
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Evaluation of anatomical and functional success in canalicular laceration repair using anterior segment optical coherence tomography and dacryoscintigraphy by Çisil Erkan Pota, Özge Ekin Geçer Şerifoğlu, Aslı Çetinkaya Yaprak, Hatice Deniz İlhan, Adil Boz

“…Conclusion: Although patients did not report epiphora after canalicular laceration repair, our observations indicated potential functional and anatomical differences in dacryoscintigraphy and anterior segment OCT compared to their healthy eyes. We believe that close follow-up is crucial to identify and address any issues that may arise in the future following surgery.…”
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MicroRNA-26b inhibits cardiac remodeling after myocardial infarction by targeting ring finger protein 6 expression by Chun-Mei Tang, Qiang Su, Hai-Xia Zhao, He-Huan Sui, Jing Liang, Li-Sha Zhu, Si-Yun Yang, Tao Liu

“…Additionally, an in vitro cell model illustrated that miR-26b upregulation could increase cell viability and reduce apoptosis, whereas RNF6 overexpression reversed its effect. We also found that the miR-26b mimic could negatively modulate RNF6 expression to inactivate the ERα/Bcl-xL axis. …”
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Short-term effects of air pollution on the infectious disease spectrum in Shanghai, China: a time-series analysis from 2013 to 2019 by Yihan Lin, Hao Meng, Yong He, Wenzhuo Liang, Yiran Niu, Zhenliang Liu, Ziying Wang, Yangyang Tian, Shiyang Chang

“…BackgroundEpidemiological evidence on the effects of air pollution on infectious diseases remains inconsistent, highlighting the need for further research and analysis. We aimed to investigate the relationship between exposure to fine particulate matter (PM2.5) and ozone (O3) and the risk of national notifiable infectious diseases in Shanghai, a megacity in China.MethodsA double-pollutant model was used for each air pollutant, utilizing time-series analysis to separately apply single and distributed lag models (DLMs) to assess the exposure-lag-response relationship for 43 national notifiable infectious diseases (NNIDs) from 2013 to 2019. …”
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An analysis of ambulance re-contacts after non-conveyance: a retrospective cohort study in the Netherlands by Susanne E. de Loor, Tessa Verheij, Thomas Karol, Franciscus G. M. H. M. Cuppen, Frits van Dijk, Femke Goldstein, Joyce Janssen, Remco H. A. Ebben

“…Therefore, the aim of our study was to analyze the incidence, reasons and outcomes of ambulance re-contacts within 72 h after non-conveyance. Methods We conducted a one year (2022) retrospective study in one EMS region in the Netherlands. …”
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Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women by Jennifer W. Bea, Sylvia Wassertheil-Smoller, Betsy C. Wertheim, Yann Klimentidis, Zhao Chen, Oleg Zaslavsky, Todd M. Manini, Catherine R. Womack, Candyce H. Kroenke, Andrea Z. LaCroix, Cynthia A. Thomson

“…Studies suggest that ACE-inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) may preserve skeletal muscle with aging. We evaluated longitudinal differences in lean body mass (LBM) among women diagnosed with hypertension and classified as ACE-I/ARB users and nonusers among Women’s Health Initiative participants that received dual energy X-ray absorptiometry scans to estimate body composition (n=10,635) at baseline and at years 3 and 6 of follow-up. …”
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The Effects of High Particulate Matter Levels on Platelet Recovery in Patients Receiving Prophylactic Platelet Transfusion by Hantrakool S, Sriwichai M, Shaengkhamnang B, Leetrakool N, Niprapan P, Kawichai S, Punnachet T, Hantrakun N, Piriyakhuntorn P, Rattanathammethee T, Chai-Adisaksopha C, Rattarittamrong E, Tantiworawit A, Norasetthada L, Srichairatanakool S

“…However, its effect on platelet recovery after transfusion remains unclear.Purpose: This study aims to assess the influence of PM2.5 exposure on platelet recovery in patients with hematologic malignancies receiving prophylactic platelet transfusions.Patients and Methods: We conducted a cross-sectional study involving 66 patients with hematologic malignancies who developed chemotherapy-induced thrombocytopenia and received prophylactic platelet transfusions between January and December 2021. …”
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Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3+ T Cell through Modulation of CD11b+ Cell Function by Jianbo Wu, Jian Gu, Shun Zhou, Hao Lu, Yunjie Lu, Ling Lu, Xuehao Wang

“…Finally, IL-22Ab modulated the expression of cytokines and costimulatory molecules in CD11b+ cells in aGVHD mice. We therefore conclude that IL-22Ab administration represents a viable approach for treating aGVHD.…”
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Novel Prognostic Factors Associated with Cell Cycle Control in Sporadic Medullary Thyroid Cancer Patients by Raffaele Pezzani, Loris Bertazza, Elisabetta Cavedon, Simona Censi, Jacopo Manso, Sara Watutantrige-Fernando, Gianmaria Pennelli, Francesca Galuppini, Susi Barollo, Caterina Mian

“…PTTG1 expression and Ki-67 levels were statistically different among the groups with remitted or persistent disease (p<0.05 and p<0.01, respectively). We found a significant correlation between the expressions of AURKA and PTTG1 (p<0.0002, r=0.5298) and between the expressions of PTTG1 and Ki-67 (p=0.01). …”
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Towards equitable carbon responsibility: Integrating trade-related emissions and carbon sinks in urban decarbonization by Junliang Wu, Yafei Wang, Shuya Zhang, Yu Zhu, Bingyue Fu, Zhihui Zhang, Hanxi Chen, Shaoqing Chen

“…However, the combined impact of trade-related carbon leakage and forest carbon sinks on CMR allocation remains poorly understood. Here, we develop an integrated CMR allocation framework that accounts for both carbon leakage and variation of forest carbon offsets. …”
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Prediction model, risk factor score and ventilator-associated pneumonia: A two-stage case-control study by Hua Meng, Yuxin Shi, Kaming Xue, Di Liu, Xiongjing Cao, Yanyan Wu, Yunzhou Fan, Fang Gao, Ming Zhu, Lijuan Xiong

“…Methods: This study aimed to establish a weighted risk scoring system to examine VAP risk among a two-stage VAP case-control study, and to evaluate the diagnostic performance of risk factor score (RFS) for VAP. We constructed a prediction model by least absolute shrinkage and selection operator (LASSO), random forest (RF), and extreme gradient boosting (XGBoost) models in 363 patients and 363 controls, and weighted RFS was calculated based on significant predictors. …”
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Ddx21 mutant peptide is an effective neoantigen in prophylactic lung cancer vaccines and activates long-term anti-tumor immunity by Zhe Zhang, Yimeng Xia, Yimeng Xia, Zhihong Wang, Yaxing Sun, Dan Pu, Yijia He, Ruixian Liu, Yanru Zhang, Yan Liu, Junzhi Yu, Shiyang Ning, Baisui Feng, Yaohe Wang, Na Wang

“…MethodsTo investigate the fundamental reason for the difference between KPL 160302S and KPL 160424S vaccines, we employed bioinformatics methods and immune related experiments to explore the effects and mechanisms of the screened neoantigens. …”
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Effect of Endotoxemia in Suckling Rats on Pancreatic Integrity and Exocrine Function in Adults: A Review Report by Jolanta Jaworek, Barbara Tudek, Paweł Kowalczyk, Michalina Kot, Joanna Szklarczyk, Anna Leja-Szpak, Piotr Pierzchalski, Joanna Bonior, Artur Dembiński, Piotr Ceranowicz, Zygmunt Warzecha, Katarzyna Nawrot-Porąbka, Krzysztof Gil

“…The effects of LPS applied to the suckling rats on the pancreas of adult animals have not been previously explored. We present the impact of neonatal endotoxemia on the pancreatic exocrine function and on the acute pancreatitis which has been investigated in the adult animals. …”
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Dynamic physiology and transcriptomics revealed the alleviation effect of melatonin on Reaumuria trigyna under continuous alkaline salt stress by Xuebo Li, Lei Wang, Heyi Wang, Rui Hao, Lunkai Gao, Hongbo Cui, Hai Wu, Xiaodong Wu, Tong Qiao, Weijie Bai, Liming Zhang

“…Despite significant progress in understanding plant salt tolerance, research on the positive effects of melatonin on Reaumuria trigyna, particularly its impact on seed germination and the underlying physiological and molecular mechanisms, remains limited.MethodsIn this study, we evaluated the physiological responses of Reaumuria trigyna under continuous alkaline salt stress and examined the effect of melatonin on seed germination.ResultsOur results demonstrate that melatonin at concentrations of 300μmol/L significantly enhances plant growth and promotes the accumulation of osmotic regulators. …”
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Relationship between prenatal metals exposure and neurodevelopment in one-year-old infants in the CLIMB study by Xiao-Yuan Fan, Xian-Shu Lin, Bing-Rui Yang, Han-Wen Zhang, Feng Tang, Jia-Jia Tang, He-Bin Chi, Toby Mansell, Noora Kartiosuo, Yin-Yin Xia, Ting-Li Han, Hua Zhang, Philip Baker, Richard Saffery

“…However, most studies focus on individual metals, neglecting combined effects. Objectives: We aimed to assess the effects of both single and combined prenatal metals exposure on one-year-old infants’ neurodevelopment. …”
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Coccidia Species and Geographical Distribution in Genus <i>Sus:</i> A Scoping Review by Hongyu Han, Hui Dong, Qiping Zhao, Shunhai Zhu, Bing Huang

“…Coccidiosis is a common cause of diarrhea in suckling piglets worldwide that directly reduces piglets’ immunity and increases the risk of infection with other enteropathogens, leading to increased clinical infection and mortality and consequent economic losses in the global pig industry. We searched the available literature to date, including English and Chinese articles, using six electronic bibliographic databases, including PubMed, ScienceDirect, Web of Science, CNKI, VIP Chinese Journal Database, and Wanfang Data. …”
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Electrochromism via reversible electrodeposition of solid iodine by Shanlin Li, Yingyu Chen, Zhen Wang, Mengmeng Wang, Xianglin Guo, Xueqing Tang, Xiaoyu Wang, Wende Lai, Meiyun Tong, Changhong Wang, Shan Cong, Fengxia Geng, Yong Chen, Zhigang Zhao

“…However, the electrochromic phenomenon has rarely been observed in non-metallic elemental substances. Herein, we propose the development of non-metallic iodine electrodeposition-based electrochromic dynamic windows using a water-in-salt electrolyte containing iodine ions. …”
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