Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters by Luiza Wilges Kist, Angelo Luis Piato, João Gabriel Santos da Rosa, Gessi Koakoski, Leonardo José Gil Barcellos, João Sarkis Yunes, Carla Denise Bonan, Maurício Reis Bogo

“…Behavioral repertoire represents the consequence of a diversity of physiological and biochemical alterations. In this study, we assessed behavioral patterns and whole-body cortisol levels of adult zebrafish (Danio rerio) exposed to cell culture of the microcystin-producing cyanobacterium M. aeruginosa (MC-LR, strain RST9501). …”
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Unraveling the interplay between NDVI, soil moisture, and snowmelt: A comprehensive analysis of the Tibetan Plateau agroecosystem by Di Wei, Lin Yan, Ziqi Zhang, Jia Yu, Xue’er Luo, Yun Zhang, Bo Wang

“…Using geostatistical methods such as trend analysis, cross-correlation, random forest algorithm, and Granger causality, we explore the temporal dynamics and causal relationships among these ecological variables. …”
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Real-time shear wave elastography in measuring normal ileocolon intestinal wall stiffness using colonoscopy as reference: A single-center research by Shuo Wang, Shihui Li, Shuling Chen, Manying Li, Xiaoyan Xie, Mao Ren, Yujun Chen

“…The threshold value of SWE in differentiating normal and abnormal intestine was determined using ROC curve analysis with the largest Youden index, and the diagnostic performance of this threshold was evaluated. We explored the effects of gender, age, depth and type of the targeted intestinal segment on the intestinal wall elasticity by t test and logistic linear regression analysis. …”
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Flood risk vulnerability assessment using GIS and hydraulic modeling, case study of the Fez river watershed, Morocco by Essahlaoui Narjisse, El Ouali Abdelhadi, Rhazi Abdelaziz, Alitane Abdennabi, Ijlil Safae, Mohajane Meriame, Ammari Zakaria, Oumou Abdellah, Khrabcha Abdelali, El Hafyani Mohamed, Essahlaoui Ali, Aouragh My Hachem, Van Rompaey Anton

“…Weather-related floods in the Fez river watershed constitute the natural hazard that threatens property. In this work, we adopted an approach based on the modeling of flow processes using the HEC-RAS model. …”
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Annual cycle variations in the gut microbiota of migratory black-necked cranes by Yujia Zhang, Ruifeng Ma, Suolangduoerji, Shujuan Ma, Shujuan Ma, Akebota Nuertai, Ke He, Hongyi Liu, Ying Zhu

“…However, the annual dynamics of gut microbiota in migratory birds remain unclear, hindering our understanding of their environmental adaptation.MethodsHere, we collected fecal samples from black-necked cranes (Grus nigricollis) across four seasons at their breeding grounds and used wintering ground data from databases to characterize their gut microbial compositions throughout the year.Results and discussionThe results showed that the gut microbiota was clustered by season (Bray-Curtis: R2 = 0.348, p < 0.001; UniFrac: R2 = 0.352, p < 0.001). …”
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Synergetic effects of H2O2 concentration and pH value on corrosion behavior of biomolecular coatings on 3D-printed porous low elastic modulus titanium alloy scaffolds under equilib... by Jia-Yi Wen, Her-Hsiung Huang

“…We investigated the synergistic effects of H2O2 concentration and pH on corrosion behavior of biomolecular, type I collagen, coatings on 3D-printed porous low elastic modulus Ti–24Nb–4Zr–8Sn (Ti2448) alloy scaffolds under equilibrium conditions in simulated inflammatory environment (i.e., acidic environment containing H2O2). …”
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Analytical and clinical validation of a novel MeltPlus TB-NTM/RIF platform for simultaneous detection of Mycobacterium tuberculosis complex, Non-Tuberculous Mycobacteria and rifamp... by Zhuo Wang, Yuanwu Zou, Zihan Wei, Guanghong Bai, Xiaolin Wang, Shaoyi Qu, Jie Shi, Yaping Jiang, Cuijiao Gu

“…BackgroundRapid and accurate diagnosis of tuberculosis, particularly rifampin (RIF)-resistant tuberculosis (RR-TB) and Non-Tuberculous Mycobacteria (NTM), is essential for implementing appropriate proper therapy to benefit patients and improve TB/NTM patient management.MethodsIn this study, we developed a novel MeltPlus MTB-NTM/RIF platform, designed to simultaneously detect Mycobacterium tuberculosis complex (MTBC), NTM and RIF resistance. …”
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Major facility superfamily sugar transporter protein SsMFSST1 regulates Sporisorium scitamineum mating, pathogenicity, and sugar transport/absorption by Yi Zhang, Yongding He, Meixin Yan, Shilong Zhang, Sisi Zhou, Wankuan Shen

“…On YePSA medium, the gene SsMFSST1 does not affect the growth, spore morphology, colony morphology, and oxidative stress ability of the haploid spores of S. scitamineum. Therefore, we speculate that the SsMFSST1 gene may regulate the expression of key genes related to the synthesis pathway of the small molecule signaling substance cAMP or tryptophol, affecting the synthesis of the signaling substance cAMP or tryptophol, thereby affecting the sexual mating and pathogenicity of S.scitamineum. …”
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The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study by Shaofei Su, Shen Gao, Enjie Zhang, Jianhui Liu, Shuanghua Xie, Yue Zhang, Ruixia Liu, Wentao Yue, Chenghong Yin

“…This study aimed to investigate the association between serum ferritin levels and the incidence of GDM. Methods We conducted a prospective cohort study involving 10,871 pregnant women from the China Birth Cohort Study. …”
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Selective dorsal rhizotomy long-term effects on functional motility in Jordanian children with spastic cerebral palsy by Yazan E. Al-kharabsheh, Anas Said, Ismail A. Ismaiel, Issam Khawaja, Marwan Altaher, Ali Bani-Ahmed, Carmen M. Cirstea, Carmen M. Cirstea

“…SDR was introduced in Jordan in 2019. We performed the first assessment of the long-term effects on motor function in Jordanian children with spastic CP (SCP) who underwent SDR.MethodsA retrospective cohort study of 43 patients (28 boys, 15 girls, mean ± SD age at surgery, 6.2 ± 2.5 years, 67.4% with diplegia, 30.2% quadriplegia, and 2.3% hemiplegia, 97.7% bilateral deficits) who received SDR (42 bilateral) was conducted between 01/01/2019 and 03/01/2023. …”
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Optimising Growth, Immunity, and Gene Expression in Broiler Chickens Through Dietary Threonine Levels and Oil Inclusion by Mohamed I. El‐Katcha, Mosaad A. Soltan, Heba I. Ghamry, Abeer F. El‐Nahas, Laila A. Al‐Shuraym, Ostan Mihaela, Rada Olga, Rasha E. Azab, Ahmed Abdeen, Mustafa Shukry, Set A. El‐Shobokshy

“…Objectives This research examined the effects of consuming threonine (Thr) in various forms levels with low or high oil on broiler chickens' growth and immunity. Methods We investigate the growth performance, feed efficiency, immune response, intestinal morphology, absorptive capacity, and expression of some genes related to the feed intake (Pro‐opiomelanocortin [POMC]), fatty acid synthesis (Acetyl‐CoA Carboxylase [ACC]), immunity (lipopolysaccharide‐induced tumour necrosis like alpha factor [LITAF]), and heat shock protein 70 (HSP70). …”
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The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach by Irena Markova, Denisa Miklankova, Martina Hüttl, Petr Kacer, Jelena Skibova, Jan Kucera, Radislav Sedlacek, Tereza Kacerova, Ludmila Kazdova, Hana Malinska

“…Renal dysfunction is also affected by the production of proinflammatory and profibrotic factors secreted from adipose tissue, which can in turn directly impair kidney cells and potentiate insulin resistance. In this study, we investigated the manifestation of renal lipid accumulation and its effect on renal dysfunction in a model of metabolic syndrome—the hereditary hypertriglyceridemic rat (HHTg)—by assessing microalbuminuria and targeted urinary proteomics. …”
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Effect of ethnicity and other sociodemographic factors on attendance at ophthalmology appointments following referral from a Diabetic Eye Screening Programme: a retrospective cohor... by James Banks, Adnan Tufail, Ling Zhi Heng, Josef Huemer, Christopher G Owen, Alicja R Rudnicka, Yasir Khan, Abraham Olvera-Barrios, Michael Seltene, Mumina Khatun, Catherine A Egan, Zoe Ockrim, Matilda Pitt, Daisy Williams, Celestine Rutowska

“…Background/aims To examine the association between sociodemographic characteristics and attendance at Hospital Eye Service (HES) referrals from the Diabetic Eye Screening Programme (DESP), in a large, ethnically diverse urban population.Methods Retrospective cohort study (4 January 2016–12 August 2019) of people with diabetic retinopathy (DR) referred from an English DESP to a tertiary referral eye hospital. We conducted a multivariable logistic regression with attendance as the primary outcome, controlling for age, sex, ethnicity, Index of Multiple Deprivation, best eye visual acuity and baseline DR grade.Results Of 7793 people referred (mean age 64 years, 62.6% male, 13.9% white, 12.5% black, 25.3% South Asian, 6.5% any other Asian background, 19.3% no recorded ethnicity and 20.9% of ‘Other’ ethnic origin), 69% attended. …”
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The International Vitreoretinal B-Cell Lymphoma Registry: a protocol paper by David J Wilson, Valérie Touitou, Justine R Smith, Manabu Mochizuki, Hiroshi Takase, Steven Yeh, Alexandra L Farrall, H Nida Sen, Daniel V Vasconcelos-Santos, Joke H de Boer, Ninette H ten Dam-van Loon, Janet L Davis, Anthony J Hall, Mark H B Radford

“…Diverse treatments are used, but there is a limited medical evidence to differentiate their effectiveness. We designed an international registry that would collect diagnostic, treatment and outcomes data, to establish new evidence for the management of this cancer.Methods and analysis The International Vitreoretinal B-Cell Lymphoma Registry will accrue data retrospectively for individuals aged 18 years or older, diagnosed with new or recurrent vitreoretinal B-cell lymphoma on or after 1 January 2020. …”
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Association of serum and local GRP78 and CHOP expressions with disease progression in patients with non-traumatic osteonecrosis of femoral head by Peng Zhang, Qing-He Ye, Wen-Xiu Zhu, Yong-Heng Zhao, Hong-Xun Zhu, Biao-Fang Wei

“…Objective The current study aimed to investigate the association of glucose-regulated protein 78 (GRP78) as well as CCAAT/enhancer-binding protein homologous protein (CHOP) expressions in serum and femoral head (FH) tissues with NT-ONFH’s severity. Methods We enrolled NT-ONFH patients (n = 150) alongside healthy controls (HCs, n = 150). …”
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Post-craniotomy infections: A point-by-point approach by Giovanni Carone, Marta Bonada, Evelyn Gisell Belotti, Eugenia D'Angeli, Annica Piccardi, Fabio Martino Doniselli, Guido Gubertini, Cecilia Casali, Francesco DiMeco, Massimiliano Del Bene

“…Research question: To address these unresolved questions through a comprehensive literature review. Material and methods: We conducted a detailed literature review using the keywords ''Infection, Craniotomy, Neurosurgery,'' on PubMed, which yielded 2330 articles. …”
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Spatial-Temporal Changes and Influencing Factors of Regional Technological Innovation Efficiency in China: A Three Entity Comparative Perspective by Ye Lei, Zhang Ting, Cao Xianzhong, Zeng Gang

“…The reason for the insignificant effect of enterprise-research institute collaborative innovation on research institutes' efficiency may be that both research institutes and firms consider technological application and development as the main goal of collaborative innovation, and collaborative innovation with firms crowds out the internal innovation resources of research institutes and inhibits their technological innovation activities. We contribute to the literature on regional innovation systems by comparing the differences in the technological innovation efficiency of the main innovation entities in the regional innovation systems of a transition economy. …”
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Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions by Jin-Hyun Park, Yu-Bin Shin, Dooyoung Jung, Ji-Won Hur, Seung Pil Pack, Heon-Jeong Lee, Hwamin Lee, Chul-Hyun Cho, Chul-Hyun Cho

“…This study employed extended Geneva minimalistic acoustic parameter set for acoustic feature extraction and extracted statistical attributes from time series-based physiological responses. We developed ML models that predict the upper tertile group for various anxiety symptoms in SAD using Random Forest, extreme gradient boosting (XGBoost), light gradient boosting machine (LightGBM), and categorical boosting (CatBoost) models. …”
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Focal therapy of prostate cancer: Use of artificial intelligence to define tumour volume and predict treatment outcomes by Wayne G. Brisbane, Alan M. Priester, Anissa V. Nguyen, Mark Topoozian, Sakina Mota, Merdie K. Delfin, Samantha Gonzalez, Kyla P. Grunden, Shannon Richardson, Shyam Natarajan, Leonard S. Marks

“…Utilising Unfold AI (FDA‐cleared 2022), which generates a 3D map of GG ≥ 2 PCa margins, we retrospectively estimated TV for each patient. …”
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Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study by Changjiang Li, Shun Zhao, Yingkai Li, Songyuan He, Wen Jian, Yanci Liu, Zichao Cheng, Hongyu Peng

“…However, the relationship between the TyG index and prognosis in patients with H-type hypertension combined with CHD has not yet been reported. In this study, we investigated the relationship between the TyG index and adverse outcomes in patients with H-type hypertension combined with CHD. …”
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