A comprehensive analysis of the effect of quorum-sensing molecule 3-oxo-C12-homoserine lactone on Candida auris and Candida albicans by Fruzsina Kovács, Ágnes Jakab, Noémi Balla, Zoltán Tóth, Dávid Balázsi, Lajos Forgács, Andrea Harmath, Aliz Bozó, Ágota Ragyák, László Majoros, Renátó Kovács

“…RNA-sequencing transcriptome analysis of C. auris revealed 67 and 306 upregulated genes, as well as 111 and 168 downregulated genes, in response to 100 and 200-μM HSL, respectively. We identified 45 overlapping upregulated and 25 overlapping downregulated genes between the two HSL concentrations. …”
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Time to Exhale: Additional Value of Expiratory Chest CT in Chronic Obstructive Pulmonary Disease by Joshua Gawlitza, Frederik Trinkmann, Hans Scheffel, Andreas Fischer, John W. Nance, Claudia Henzler, Nils Vogler, Joachim Saur, Ibrahim Akin, Martin Borggrefe, Stefan O. Schoenberg, Thomas Henzler

“…Until now, inspiratory chest computed tomography (CT) has been considered as the preferred imaging method in these patients. We hypothesized that expiratory CT may be superior to demonstrate pathophysiological changes. …”
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Incidence of Malignancies and the Association with Biological Disease-Modifying Antirheumatic Drugs in Japanese Patients with Rheumatoid Arthritis: A Time-Dependent Analysis from t... by Masayoshi Harigai, Eiichi Tanaka, Eisuke Inoue, Ryoko Sakai, Naohiro Sugitani, Shigeyuki Toyoizumi, Naonobu Sugiyama, Hisashi Yamanaka

“…Using patient registry data, we determined malignancy risk, stratified by bDMARD use, among Japanese patients with RA versus the Japanese general population and investigated whether bDMARD use is a time-dependent risk factor for the development of malignancy. …”
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Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model by Sang-A. Oh, Song-I. Seol, Dashdulam Davaanyam, Seung-Woo Kim, Ja-Kyeong Lee

“…Functional inhibition of HMGB1 by intranasal administration of an HMGB1 A box 4 h post-PTS significantly suppressed NETosis induction, reduced infarct volume, and improved neurological deficits, confirming the pivotal role of HMGB1 in NETosis induction. Notably, we observed a rapid platelet activation and concomitant HMGB1 induction within activated platelets after PTS. …”
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Can electronic monitoring with a digital smart spacer support personalised medication adherence and inhaler technique education in patients with asthma?: Protocol of the randomised... by Job F. M. van Boven, Boudewijn H.J. Dierick, Maria Achterbosch, Sandra Been-Buck, Titia Klemmeier, Susanne J. van de Hei, Paul Hagedoorn, Huib A.M. Kerstjens, Janwillem W.H. Kocks

“…The aim of this study is to assess the feasibility of undertaking a definitive randomised controlled trial of personalised, smart spacer data-driven education and explore clinical benefits.Methods and analysis We present the design of the multicentre, randomised controlled OUtcomes following Tailored Education and Retraining: Studying Performance and AdherenCE feasibility trial of 2 months. …”
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An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia by Theodoros Iliakis, Niki Rougkala, Panagiotis T. Diamantopoulos, Vasiliki Papadopoulou, Fani Kalala, Konstantinos Zervakis, Nefeli Giannakopoulou, Polixeni Chatzinikolaou, Georgia Levidou, Eleftheria Lakiotaki, Penelope Korkolopoulou, Efstratios Patsouris, Eleni Variami, Nora-Athina Viniou

“…In the setting of SM-AHNMD, eradicating the nonmast cell malignant clone greatly affects prognosis. We report a case of an adult patient with SM associated with B-lineage acute lymphoblastic leukemia (B-ALL). …”
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Novel pyroptosis-immune-related lncRNA signature exhibits a distinct immune cell infiltration landscape in breast cancer by Dedi Kong, Dedi Kong, Hongju Cheng, Meihong Wang

“…Single-cell sequencing data from GSE176078 were used to validate the immune cell infiltration landscape of the identified lncRNA signatures.ResultsWe identified a six-lncRNA pyroptosis-immune signature comprising MAPT.AS1, CTA.384, D8.34, RP11.561, I11.3, HID1.AS1, AC097713.3, and USP2.AS1. …”
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Salivary peptidomic profiling of chronic gingivostomatitis in cats by matrix‐assisted laser desorption/ionization‐time‐of‐flight mass spectrometry and nanoscale liquid chromatograp... by Sekkarin Ploypetch, Apisit Pornthummawat, Sittiruk Roytrakul, Janthima Jaresitthikunchai, Narumon Phaonakrop, Sabrina Wahyu Wardhani, Sitthichok Lacharoje, Somporn Techangamsuwan

“…Methods Case‐control cross‐sectional study. We compared the salivary peptide profiles of diseased and healthy cats. …”
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Potential Involvement of IL-17F in Asthma by Kyoko Ota, Mio Kawaguchi, Satoshi Matsukura, Masatsugu Kurokawa, Fumio Kokubu, Junichi Fujita, Yuko Morishima, Shau-Ku Huang, Yukio Ishii, Hiroaki Satoh, Nobuyuki Hizawa

“…IL-17F-induced CCL20 may attract Th17 cells into the airway resulting in the recruitment of additional Th17 cells to enhance allergic airway inflammation. We have recently identified, for the first time, that bronchial epithelial cells are its novel cell source in response to IL-33 via ST2-ERK1/2-MSK1 signaling pathway. …”
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The potential endocrine-disrupting of fluorinated pesticides and molecular mechanism of EDPs in cell models by Yalan Liu, Fengzhong Wang, Lin Li, Bei Fan, Zhiqiang Kong, Jianxin Tan, Minmin Li

“…The research into fluorinated pesticides is somewhat superficial, with the majority of review articles in this field focusing on the structural characteristics, biodegradation processes, and environmental risks associated with these pesticides. In this study, we compared and investigated the research development processes of seven types of fluorine-containing pesticides and five types of fluorinated endocrine disruptors. …”
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Rockfish abundance, recruitment, and community structure trends in the western Strait of Juan de Fuca, Washington, 2005-2023 by Shawn E. Larson, Katie Shelledy, Daniela Escontrela Dieguez, Jeff Christiansen, Amy Y. Olsen, Zachary Randell, Megan H. Williams, Chris VanDamme, Dayv Lowry, William Jasper

“…All sites displayed relative stability in fish community structure over time. We documented low levels of young-of-the-year (YOY) rockfish recruitment over the years with one major recruitment event in 2016. …”
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Impact of immunosuppressive regimens on antibody response after COVID-19 vaccination among Thai kidney transplant recipients by Nuttasith Larpparisuth, Kritsada Pongsakornkullachart, Nartsiri Ratchawang, Attapong Vongwiwatana, Peenida Skulratanasak

“…However, there are few studies on the efficacy of the ChAdOx1 nCoV-19 (AstraZeneca) vaccine compared between various immunosuppressive regimens. Methods: We conducted a prospective cohort study at Siriraj Hospital, Bangkok, Thailand. …”
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First Case of Respiratory Infection in Rabbits Caused by <i>Alcaligenes faecalis</i> in Romania by Vlad Iorgoni, Ionica Iancu, Ionela Popa, Alexandru Gligor, Gabriel Orghici, Bogdan Sicoe, Corina Badea, Cristian Dreghiciu, Călin Pop, Timea Bochiș, Janos Degi, Luminita Costinar, Corina Pascu, Viorel Herman

“…Notably, <i>A. faecalis</i> is often characterized by a high degree of antibiotic resistance, complicating treatment efforts. In the current study, we present a case involving a 3-month-old male rabbit that developed a generalized infection, ultimately leading to the animal’s death. …”
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Reflections of Foster Youth Engaging in the Co-Design of Digital Mental Health Technology: Duoethnography Study by Ifunanya Ezimora, Tylia Lundberg, Dylan Miars, Jeruel Trujeque, Ashley Papias, Margareth V Del Cid, Johanna B Folk, Marina Tolou-Shams

“…As the digital health field increasingly shifts toward using co-design methods to develop digital mental health technologies for underserved youth populations, we offer recommendations for researchers seeking to ethically and effectively engage youth co-designers. …”
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The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction by Na Yang, Xiaoyan Li, Bo Wu, Longhao Dai, Shaobin Yang, Qinning Zhang, Shaobin Jia

“…This study aimed to assess the predictive value of P‐wave variables for post‐AMI NOAF. Methods We retrospectively analyzed 1581 AMI patients with no prior AF, using follow‐up data from January 2023 to January 2024. …”
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Changes in the intestinal microbiota induced by the postnatal environment and their association with hypertension by Patrizia Dardi, Camille Perella Coutinho, Sarah de Oliveira, Simone Aparecida Teixeira, Renaide Rodrigues Ferreira Gacek, Eduardo Purgatto, Marco Aurélio Ramirez Vinolo, Marcelo Nicolás Muscará, Luciana Venturini Rossoni

“…Moreover, decreased systolic blood pressure was observed in the SW group compared to the SS group in adulthood. Thus, we could establish a link between microbiota composition and hypertension development, associating it with the loss of the ''low-abundance'' bacterial taxa. …”
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Congenital Heart Disease Fetuses Have Decreased Mid-Gestational Placental Flow, Placental Malperfusion Defects, and Impaired Growth by Rebecca Josowitz, MD, PhD, Deborah Y. Ho, MD, MPH, Somya Shankar, BS, Antara Mondal, MS, Alexis Zavez, PhD, Rebecca L. Linn, MD, Zhiyun Tian, MD, J. William Gaynor, MD, Jack Rychik, MD

“…Objectives: The purpose of this study was to determine if CHD fetuses with decreased placental blood flow have placental pathology at birth and if there is a relationship between placental blood flow, placental pathology, and outcomes. Methods: We performed a prospective case-control study of 38 CHD fetuses, including 28 with single ventricle physiology and 36 controls. …”
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The Predictive Value of Growth Differentiation Factor-15 in Recurrence of Atrial Fibrillation after Catheter Ablation by Ying Wei, Shuwang Liu, Haiyi Yu, Yuan Zhang, Wei Gao, Ming Cui, Lei Li

“…The study sought to explore the association between growth differentiation factor-15 (GDF-15) and the incidence of recurrent events among AF patients after the ablation procedure. We prospectively included 150 consecutive AF patients who underwent RFCA. …”
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Factors Associated with HIV Testing among Male Students Who Have Engaged in Sexual Behaviour in Zhejiang Province, China by Zhongrong Yang, Hui Wang, Qiaoqin Ma, Weiyong Chen, Xiang Zhao, Tingting Jiang, Wanjun Chen, Xin Zhou, Lin Chen

“…The graveness of the AIDS epidemic among students necessitates this emphasis. Moreover, we recommend deploying condom-dispensing machines or HIV testing facilities across the campus for easy access to preventive and testing services for HIV.…”
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Trends in palliative care utilization among older adult decedents with and without cancer in Taiwan: a population-based comparative studyResearch in context by Yu-Tai Lo, Tzu-Jung Chuang, Yu-Tung Huang, Yi-Lin Wu, Yi-Ching Yang, Chung-Yi Li

“…Methods: The study utilized data from the Health and Welfare Data Science Center in Taiwan, covering demographic and healthcare variables for 588,010 decedents aged 65+ years who died between 2010 and 2020. We used Poisson regression to investigate the temporal trends in palliative care utilization during the last six months of life. …”
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