Water–rock interaction in the geothermal systems related to post-collision zone volcanism: A case study based on multivariate statistical analysis from the Kavak geothermal field (... by Gündüz, Mesut, Bozdağ, Ayla, Bayram, Ali Ferat, Bozdağ, Ali, Asan, Kürşad, Sardini, Paul

“…Statistical approaches are also vital for the quantitative models, and mainly combined with the traditional methods. In this study, we re-evaluate the published data, including water chemistry and volcanic and metamorphic whole-rock geochemistry from the Kavak geothermal field (Konya, Turkey) by using multivariate statistical analysis (e.g. factor analysis and clustering analysis) to research possible interaction between the thermal waters and surrounding rocks.The Kavak geothermal field (KGF) overlies a metamorphic basement composed of the Paleozoic metacarbonates and metaclastic rocks, yet is located near the Erenlerdağ–Alacadağ volcanic complex (ErAVC). …”
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RECIST 1.1 versus mRECIST for assessment of tumour response to molecular targeted therapies and disease outcomes in patients with hepatocellular carcinoma: a systematic review and... by Yao Yang, Yuping Bai, Hongli Yu, Qiang Zhu, Xiaoyu Xie, Yuemin Feng

“…A systemic review was performed to compare the objective response rate (ORR) and disease control rate (DCR) and a meta-analysis was conducted to compare the correlation between objective response and overall survival (OS).Design Systematic review and meta-analysis using the Grading of Recommendations Assessment, Development and Evaluation approach.Data sources EMBASE, PubMed, Web of Science and Cochrane Library were searched through 31 December 2021.Eligibility criteria We included studies assessing the efficacy of molecular targeted therapy for HCC according to both RECIST 1.1 and mRECIST.Data extraction and synthesis Two investigators extracted data independently. …”
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Intercropping wheat and rapeseed in Cd-polluted weakly alkaline soil: Crop productivity, Cd enrichment capacity, and rhizosphere soil characteristics by Xu Li, Hanying Kong, Junchuan Huang, Jiaoyuan Yan, Wei He, Hui Wang, Hong Pan, Quangang Yang, Yuping Zhuge, Yanhong Lou

“…However, single-species phytoremediation can be challenged by both its limited metal ion extraction efficiency and crop yield. In this study, we investigated the beneficial effects of intercropping rapeseed (Brassica napus) and wheat (Triticum spp.) varieties (Jimai and Zhengyu) with different Cd accumulation potentials on several agronomic traits. …”
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Attenuation of Myocardial Injury by HMGB1 Blockade during Ischemia/Reperfusion Is Toll-Like Receptor 2-Dependent by Jan Mersmann, Franziska Iskandar, Kathrina Latsch, Katharina Habeck, Vera Sprunck, René Zimmermann, Ralf R. Schumann, Kai Zacharowski, Alexander Koch

“…Plasma levels of HMGB1 were increased MI/R in TLR2−/−-mice after CABG surgery in patients carrying a TLR2 polymorphism (Arg753Gln). We here provide evidence that absence of TLR2 signalling abrogates infarct-sparing effects of HMGB1 blockade.…”
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FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy by Na Zhang, Yang Meng, Song Mao, Huiling Ni, Canhua Huang, Licong Shen, Kun Fu, Lu Lv, Chunhong Yu, Piyanat Meekrathok, Chunmei Kuang, Fang Chen, Yu Zhang, Kai Yuan

“…However, clinical characterization of dysregulated O-GlcNAcylation homeostasis in EC and interrogating its molecular mechanism remain incomplete. Here we report that O-GlcNAcylation level is positively correlated with EC histologic grade in a Chinese cohort containing 219 tumors, validated in The Cancer Genome Atlas dataset. …”
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The efficacy of Artichoke leaf extract conjugated with organic zinc nanoparticles on growth, carcass traits and blood biochemical parameters of broilers by Elwy A. Ashour, Ahmed K. Aldhalmi, Mahmoud Kamal, Salem S. Salem, Samir A. Mahgoub, Abdulmohsen H. Alqhtani, Mahmoud Madkour, Ahmed A. Elolimy, Mohamed E. Abd El-Hack, Ayman A. Swelum

“…There were no notable variations in carcass features between treatments, except for the percentage of carcass, dressing, thigh, heart, and intestine cecum in the control group. In addition, we found significant differences in total protein, albumin, and globulin levels between treatments, with the control group showing higher levels compared to the other two groups. …”
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Formalin Fixation as Tissue Preprocessing for Multimodal Optical Spectroscopy Using the Example of Human Brain Tumour Cross Sections by Mona Stefanakis, Anita Lorenz, Jörg W. Bartsch, Miriam C. Bassler, Alexandra Wagner, Marc Brecht, Axel Pagenstecher, Jens Schittenhelm, Barbara Boldrini, Sabrina Hakelberg, Susan Noell, Christopher Nimsky, Marcos Tatagiba, Rainer Ritz, Karsten Rebner, Edwin Ostertag

“…As optical spectroscopy is sensitive to these variations, we evaluate the effects of formalin fixation on multimodal brain tumour data in this proof-of-concept study. …”
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Putative regulatory functions of SNPs associated with bronchial asthma, arterial hypertension and their comorbid phenotype by I. A. Goncharova, E. Yu. Bragina, I. Zh. Zhalsanova, M. B. Freidin, M. S. Nazarenko

“…Linkage disequilibrium (LD) of single nucleotide polymorphisms (SNPs) of TLR4/AL160272.2 (rs1927914, rs1928298, rs7038716, rs7026297, rs7025144) was estimated in the Slavs of West Siberia. We further investigated an association of SNPs in TLR4/AL160272.2 (rs1927914, rs7038716, rs7025144), SERPINA1 (rs1980616), ATXN2/BRAP (rs11065987), IL2RB (rs2284033), NT5C2 (rs11191582), CARD8 (rs11669386), ANG/RNASE4 (rs1010461), and ABTB2/ САТ (rs2022318) genes with bronchial asthma (BA), arterial hypertension (AH) and their comorbidity. …”
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Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…Methods Our study investigates the immunological roles of extracellular vimentin (eVim) and its citrullinated form (CitVim) as a damage-associated molecular pattern (DAMP) engaging the Toll-like receptor 4 (TLR4) of human neutrophils. We used in vitro assays to study neutrophil migration through endothelial cell monolayers and activation markers such as NADPH oxidase subunit 2 (NOX2/gp91phox). …”
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Observation of ultraviolet photothermoelectric bipolar impulse in gallium-based heterostructure nanowires by Jinjie Zhu, Qing Cai, Pengfei Shao, Shengjie Zhang, Haifan You, Hui Guo, Jin Wang, Junjun Xue, Bin Liu, Hai Lu, Youdou Zheng, Rong Zhang, Dunjun Chen

“…Abstract The incorporation of thermal dynamics alongside conventional optoelectronic principles holds immense promise for advancing technology. Here, we introduce a GaON/GaN heterostructure-nanowire ultraviolet electrochemical cell of observing a photothermoelectric bipolar impulse characteristic. …”
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Predictors of Cardiovascular Autonomic Neuropathy Onset and Progression in a Cohort of Type 1 Diabetic Patients by M. Matta, A. Pavy-Le Traon, S. Perez-Lloret, C. Laporte, I. Berdugo, N. Nasr, H. Hanaire, J. M. Senard

“…However, the rate and predictors of both the development and progression of CAN have been less studied. Hereby, we assessed the rate and the major risk factors for CAN initiation and progression in a cohort of type 1 diabetic patients followed over a three-year period. …”
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Round Window Accessibility Prediction in Cochlear Implant Surgery by Salah-eddine Youbi, Omar Oulghoul, Youssef Lakhdar, Atmane Zaroual, Mohamed Chehbouni, Othmane Benhoummad, Youssef Rochdi, Abdelaziz Raji

“…Objective is to predict round window (RW) accessibility during CI surgery using high-resolution computed tomography (HRCT). Methods: We retrospectively reviewed preoperative HRCT scans of 142 patients who underwent CI surgery via the standard posterior tympanotomy approach at our ENT Head and Neck Surgery department. …”
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Virulence changes in Vibrio parahaemolyticus during the freezing of Penaeus chinensis by Zenghui Gao, Heer Ding, Ke Li, Qiang Zhang, Xubo Zhao, Liu Bin, Tianli Yue

“…To investigate these potential risks, we used frozen Penaeus chinensis as examples, and the most virulent factors of V. parahaemolyticus, including amounts, VBNC status, toxins TDH and TRH, and virulence genes tdh and trh, were determined. …”
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An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review by Reina Takeda, Kazuaki Yokoyama, Seiichiro Kobayashi, Toyotaka Kawamata, Sousuke Nakamura, Tomofusa Fukuyama, Mika Ito, Nozomi Yusa, Eigo Shimizu, Nobuhiro Ohno, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Kaoru Uchimaru, Arinobu Tojo

“…However, the occurrence of t-MN in adult T-cell leukemia/lymphoma (ATL) patients is rarely reported, possibly due to the dismal prognosis of ATL per se. Here, we report a 62-year-old female who developed t-MN only three months after the completion of conventional chemotherapy and anti-CCR4 antibody for ATL acute type. …”
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Sistem Berbasis Private Blockchain sebagai Penyedia Layanan Autentikasi Publisher-Broker-Subscriber Pada Protokol Message Queue Telemetry Transport by Muhammad Naufal Dzakie, Adhitya Bhawiyuga, Achmad Basuki

“…Therefore, in this study, we will propose a solution using Ethereum blockchain as a substitute for the authentication server. …”
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Soil-plant-animal relationships and their effect on pasture-based milk production in Hacienda Cuba, Colombia by María A. López G., Ana G. Quintero M., Juan J. Zúñiga E., Felipe Vélez S., Juan F. Naranjo R., Óscar A. Sáenz R., Andrés F. Pérez R.

“…This study describes the soil, plant, and animal components to assess the capacity for high-quality buffalo milk production. We collected soil and forage samples from the grazing area for chemical characterization and quantified the available forage supply. …”
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Improving Outcomes and Quality of Life for Patients With Hand and Foot Eczema: Randomized Study of a Patient-Centered Monitoring App by Aimee Bruch, Wanja Weigandt, Yannic Schardt, Raphael Herr, Johannes Benecke, Astrid Schmieder

“…Subgroup analysis revealed that patients who used the app with a usage frequency of less than 20% demonstrated a significant reduction in the HECSI from week 0 to week 60 (week 60: Coef=–1.275; P=.04) and a significant reduction in the Dermatology Life Quality Index (week 60: Coef=–1.246; P=.04) compared to the control group. We were able to demonstrate a significant correlation between the HECSI calculated based on pictures uploaded by patients through the app and the HECSI assessed during personal visits (ρ=0.885; P<.001), despite the potentially lower image quality of the pictures uploaded through the app. …”
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Change in Atrial Fibrillation Burden over Time in Patients with Nonpermanent Atrial Fibrillation by Philipp Krisai, Stefanie Aeschbacher, Matthias Bossard, Elena Herber, Steffen Blum, Pascal Meyre, Thilo Burkard, Michael Kühne, Stefan Osswald, Beat A. Kaufmann, David Conen

“…The natural course of atrial fibrillation (AF) is not well defined. We aimed to investigate the change in AF burden over time and its associated risk factors among AF patients. …”
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The associations between single nucleotide polymorphisms and diabetic retinopathy risk: an umbrella review by Shaofen Huang, Yonghui Feng, Ying Sun, Jiazi Liu, Pu Wang, Jingrong Yu, Xin Su, Shasha Han, Shiqi Huang, Haokun Huang, Shiyun Chen, Ying Xu, Fangfang Zeng

“…This umbrella review was conducted aiming to assess the association between genetic variations and the development of diabetic retinopathy (DR) by collecting and evaluating available systematic reviews and meta-analysis results. We evaluated the methodological quality using the Measurement Tool to Assess Systematic Reviews (AMSTAR) 2.0, estimated the summary effect size by using the random effects model and calculated the 95% prediction intervals (PIs). …”
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Forty years of HIV infection and AIDS in Taiwan: Reflection on the past and looking toward the future by Sung-Hsi Huang, Hsun-Yin Huang, Stephane Wen-Wei Ku, Po-Hsien Kuo, Kuan-Yin Lin, Guan-Jhou Chen, Chia-Chi Lee, Yen-Fang Huang, Chien-Ching Hung

“…We review the epidemiology, policies, and control programs of HIV infection in Taiwan in the past 40 years since the first case of HIV infection was diagnosed in 1984. …”
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