Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…Multiple studies have shown that an imbalance in the gut-heart axis plays an important role in the development of cardiovascular disease (CVD). We aim to explore the possible correlations between gut microbiota (GM) compositions and cardiometabolic (CM) disorder in MTX-triggered cardiotoxicity mice.Methods: MTX cumulative dose of 6 mg/kg was administered to healthy Kunming male mice to trigger cardiotoxicity, with 1 mg/kg twice weekly for a duration of 3 weeks. …”
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Abnormal glymphatic system in patients with autoimmune encephalitis: Relationship with cognitive performance by Yingchi Zhang, Dianwei Wu, Zhirong Fan, Xiuxiu Leng, Ting Wan, Xiaodan Shi, Xiaomu Wang, Xuan Wang, Changgeng Song, Fang Du, Wen Jiang

“…Objectives: We aimed to explore the impact of glymphatic function in patients diagnosed with autoimmune encephalitis (AE). …”
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Association of e-cigarette and cigarette use with self-reported chronic obstructive pulmonary disease (COPD): a multivariable analysis of a large United States data set by Alicia J. Burns, Alexander W. Steinberg, James D. Sargent, Jenny E. Ozga, Zhiqun Tang, Cassandra A. Stanton, Laura M. Paulin

“…Abstract Background Prior research has linked e-cigarette use with chronic obstructive pulmonary disease (COPD). We examined the relationship between e-cigarette use and COPD prevalence in older adults with varying cigarette use status. …”
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Unlocking barriers and strategies of halal certification for micro and small enterprises in Indonesia: Analytic network process approach by Muhammad Anwar Fathoni, Prima Dwi Priyatno, Faizi, Fadhli Suko Wiryanto, Widarto Rachbini, Suryani

“…This study would not have been possible without their generous funding and commitment to advancing research in Indonesia. We also extend our appreciation to all the respondents and participants who contributed valuable insights and data for this study, as well as to the institutions involved for their support and collaboration.…”
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Development and external validation of a dynamic nomogram for predicting the risk of functional outcome after 90 days in patients with acute intracerebral hemorrhage by Shaojie Li, Hongjian Li, Jiani Chen, Baofang Wu, Jiayin Wang, Chaocan Hong, Changhu Yan, Weizhi Qiu, Yasong Li, Hongzhi Gao

“…The developed dynamic nomogram was easy to use and demonstrated strong predictive performance (training set AUC: 0.87; test set AUC: 0.839; external validation set AUC: 0.774), excellent calibration, and clinical applicability.ConclusionThe dynamic nomogram we developed using five independent risk factors serves as a practical tool for real-time risk assessment and can help facilitate early intervention and personalized patient management, thereby improving clinical outcomes in high-risk patients.…”
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Efficacy and safety of sequential therapy for primary osteoporosis with bone formation promoters followed by bone resorption inhibitors: a meta-analysis by Yuxin Liu, Xin Liu, Yuefeng Wu, Tao Luo

“…Abstract Objective Through this study we aimed to present the latest and most comprehensive pooled analysis, providing an updated evaluation of the efficacy and safety of sequential therapy for primary osteoporosis, using bone formation promoters followed by bone resorption inhibitors. …”
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Genetically and chemically intraspecific variations of Ficus hirta provide novel insights into its protection and utilization by Jianling Chen, Qianqian Liu, Huihong Wang, Zhi Chao, Enwei Tian

“…However, little is known about the genetic background and medicinal quality of F. hirta across populations, which restricts its protection and utilization. In this study, we conducted an evaluation of the chloroplast DNA (cpDNA) genetic diversity and population structure of F. hirta in southern China, and further evaluated its medicinal quality based on HPLC fingerprinting and the content determination of the active components. …”
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The perceived workload of first-line healthcare professionals during neonatal resuscitation by Hai-Bo Huang, Kui Sang, Ming Zhou, Lin Yi, Jiang-Qin Liu, Chuan-Zhong Yang, Brenda H.Y. Law, Georg M. Schmölzer, Po-Yin Cheung

“…Little is known regarding the perceived workload and associated factors among healthcare professionals including medical doctors (MDs) and nurses/midwives who have differences in training and experiences. We aimed to characterize and compare the perceived workload between MDs and nurses/midwives who provided neonatal resuscitation. …”
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Association between white blood cell count and coronary artery bypass graft failure: an individual patient data analysis of clinical trials by Kevin R. An, Sigrid Sandner, Joyce Peper, Yanzai Zhou, Jurrien M. ten Berg, Lamia Harik, Yunpeng Zhu, Laura M. Willemsen, Qiang Zhao, Björn Redfors, Subodh Verma, Mario F. L. Gaudino

“…This study aims to explore the association between pre-operative white blood cell [WBC] count and CABG graft failure. Methods We pooled individual patient data from two randomized clinical trials with systematic CABG graft imaging. …”
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Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas by James D. Phillips, Tyler Merrill, J. Reed Gardner, R. Thomas Collins, Jenika Sanchez, Adam B. Johnson, Brian K. Eble, Larry D. Hartzell, Jay M. Kincannon, Gresham T. Richter

“…How ECG results affect subsequent propranolol usage and patient management remains unclear. We examined the value of ECG prior to propranolol therapy in a quaternary pediatric hospital. …”
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Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

“…After analyzing Ly6E expression levels in human breast cancer tissues and tumor cell lines, we generated Ly6E knockout (KO) and overexpression (OE) mouse cell lines. …”
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Efek Electro Convulsive Therapy (ECT) terhadap Daya Ingat Pasien Skizofrenia di RSJ Prof. HB. Sa’anin Padang by Ikky Nabila Nandinanti, Yaslinda Yaunin, Siti Nurhajjah

“…Impaired memory after ECT occurs in all samples (100%) with moderate impaired in the ability of immediate memory, severe impaired in the ability of recent memory, and severe impaired in the ability of remote memory. We concluded,<br />there are differences in immediate and recent memory in schizophrenic patients before and after ECT, while the ability of remote memory has not changed.…”
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Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence by Xue Li, Ling Wang, Jinghuan Lin, Yingjuan Gu, Zhihua Liu, Jing Hu

“…The synergistic and opposed effects of the two systems on virulence and antibiotic-resistance genes need further study.IMPORTANCEK. pneumoniae is an important opportunistic pathogen responsible for both human and animal infections, and the emergence of hypervirulent and multidrug-resistant K. pneumoniae has made it difficult to control this pathogen worldwide. Here, we find that CRISPR‒Cas and restriction–modification systems, which function as adaptive and innate immune systems in bacteria, have synergistic and opposed effects on virulence and antibiotic resistance genes in K. pneumoniae. …”
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Spatial and temporal variation of Antarctic microbial interactions: a study around the west Antarctic Peninsula by Swan L. S. Sow, Willem H. van de Poll, Rachel Eveleth, Jeremy J. Rich, Hugh W. Ducklow, Patrick D. Rozema, Catherine M. Luria, Henk Bolhuis, Michael P. Meredith, Linda A. Amaral-Zettler, Julia C. Engelmann

“…Comprehensive and comparative, year-round assessments of the WAP microbial community dynamics in coastal surface waters at these two locations are imperative to understand the effects of regional climate warming variations on microbial community dynamics, but this is still lacking. Results We report on the seasonal diversity, taxonomic overview, as well as predicted inter-and intra-domain causal effects (interactions) of the bacterial and microbial eukaryotic communities close to the Palmer station and at the Rothera time-series site between July 2013 and April 2014. …”
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Impact of bridging with left ventricular assist device on right ventricular function following heart transplantation by Annika Ingvarsson, Grunde Gjesdal, Saeideh Borgenvik, Anna Werther Evaldsson, Johan Waktare, Oscar Braun, Gustav J. Smith, Anders Roijer, Göran Rådegran, Carl Meurling

“…This study set out to examine the poorly investigated area of if and how pre‐treatment with LVAD impacts right ventricular (RV) function following OHT. Methods and results We prospectively evaluated 59 (LVAD n = 20) consecutive OHT patients. …”
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Genomic characterization and radiation tolerance of Naganishia kalamii sp. nov. and Cystobasidium onofrii sp. nov. from Mars 2020 mission assembly facilities by Patrick Leo, Marcus de Melo Texeira, Atul M. Chander, Nitin K. Singh, Anna C. Simpson, Andrey Yurkov, Fathi Karouia, Jason E. Stajich, Christopher E. Mason, Kasthuri Venkateswaran

“…Another yeast strain FKI-L6-BK-PAB1T, isolated from the Kennedy Space Center Payload Hazardous and Servicing Facility, was placed in the genus Cystobasidium (Cystobasidiales, Cystobasidiomycetes) and is distantly related to C. benthicum. Here we propose two novel species with the type strains, Naganishia kalamii sp. nov. …”
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Depression Paradox in Cardiovascular Outcomes of Adult Patients with Obstructive Sleep Apnea: Insights from 2 Million Nationwide Hospitalizations by Rupak Desai, Sashwath Srikanth, Shaylika Chauhan, Zainab Gandhi, Warda Shahnawaz, Aleen Rahman, Bisharah Rizvi, Akhil Jain

“…MATERIAL AND METHODS: Using the National Inpatient Sample (2018), we identified hospitalizations in the US with OSA. …”
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Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China by Hongli An, Xiamei Kang, Chenhu Huang, Chenghao Jia, Jiaqi Chen, Yingying Huang, Qianzhe Cao, Yan Li, Biao Tang, Min Yue

“…Our study aims to fill this gap by providing genomic features of the antimicrobial resistance and virulence potential of Salmonella isolates from dead duck embryos using whole-genome sequencing and in silico toolkits. We also sought to assess the virulent characterization of the major serovar isolates by experimental infection of chicken and duck embryos. …”
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THE CHARACTERISTICS OF MIRNA BINDING SITES IN MRNA OF ZFHX3 GENE AND ITS ORTHOLOGS by A. М. Kondybayeva, A. N. Akimniyazova, S. U. Kamenova, A. Т. Ivashchenko

“…TNR variability is considered to be one of the causes of the disease, but their biological function has not yet been established. We assume that TNRs are the binding sites of miRNA to mRNA and are involved in regulation of ZFHX3 gene expression. …”
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An Integrated Na₂S−Electrocatalyst Nanostructured Cathode for Sodium–Sulfur Batteries at Room Temperature by Sichang Ma, Yueming Zhu, Yadong Yang, Dongyang Li, Wendong Tan, Ling Gao, Wanwei Zhao, Wenbo Liu, Wenyu Liang, Rui Xu

“…Utilizing Na₂S as the cathode material addresses these issues, yet challenges such as Na₂S’s low conductivity as well as the shuttle effect of polysulfide still hinder RT Na–S battery development. Herein, we present a simple and cost-effective method to fabricate a Na₂S–Na₆CoS₄/Co@C cathode, wherein Na₂S nanoparticles are embedded in a conductive carbon matrix and coupled with dual catalysts, Na₆CoS₄ and Co, generated via the in situ carbothermal reduction of Na₂SO₄ and CoSO₄. …”
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