Dense integration of chlorocatechols crosslinked polyphenylene sulfide solid-state separator for Li metal-free batteries by Haitao Zhou, Lianlu Wan, Jiacheng Han, Jian-Chun Wu, Yihong Deng, Jie Gu, Huanggang Wang, Hongquan Gao, Zilong Su

“…However, the films produced by this method suffer from issues such as poor toughness, low strength, uneven thickness, and difficulties in rewinding, which limit its widespread adoption in the large-scale manufacturing of lithium batteries. In this study, we propose a hydrothermal process to introduce a chlorocatechol-based cross-linker onto the surface of highly crystalline polyphenylene sulfide (PPS) powder. …”
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Altered functional network topology properties to detect anxiety and depression caused by Crohn’s disease and disease severity by Jiaxing Yang, Kechen Yue, Jingwen Sun, Changjie Pan, Xintong Wu, Yongjun Cheng, Xiaomeng Wu, Haifeng Shi

“…Objective: Here we investigated changes in topological properties of functional brain networks among individuals with Crohn’s disease (CD) and to determine whether these changes are related to CD severity, as well as CD-associated anxiety and depression, which are regulated by the brain–gut axis mechanism. …”
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The association between bone density of lumbar spines and different daily protein intake in different renal function by Chia-Lin Lee, Kun-Hui Chen, Wei‑Ju Liu, Ching-Hsien Chen, Shang-Feng Tsai

“…However, protein intake is essential for bone health.Methods We studied the database of the National Health and Nutrition Examination Survey, 2005–2010. …”
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Comparison of Efficacy and Safety of First-Line Treatment Options for Unresectable Stage III Non-Small Cell Lung Cancer: A Retrospective Analysis by Luqing Zhao, Zhiting Zhao, Xiaoqi Yan, Fei Wu, Ning Sun, Renhong Guo, Shaorong Yu, Xiao Hu, Jifeng Feng

“…This study retrospectively compared the efficacy and safety of different first-line treatments for unresectable stage III NSCLC. Methods. We retrospectively analyzed 397 patients who received first-line treatment for unresectable stage III NSCLC. …”
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Gene networks and metabolomic screening analysis revealed specific pathways of amino acid and acylcarnitine profile alterations in blood plasma of patients with Parkinson’s disease... by A. A. Makarova, P. M. Melnikova, A. D. Rogachev, P. S. Demenkov, T. V. Ivanisenko, E. V. Predtechenskaya, S. Y. Karmanov, V. V. Koval, A. G. Pokrovsky, I. N. Lavrik, N. A. Kolchanov, V. A. Ivanisenko

“…To comprehensively analyze the pathophysiology of PD and VP, the methods of systems biology and gene network reconstruction are essential. In the current study, we performed metabolomic screening of amino acids and acylcarnitines in blood plasma of three groups of subjects: PD patients, VP patients and the control group. …”
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Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model by Haoshu Fang, Chuanfeng Hua, Stefanie Weiss, Anding Liu, Wenhui Cheng, Ralf Claus, Jürgen Rödel, Olaf Dirsch, Uta Dahmen

“…Sepsis is the primary cause of death from infection. We wanted to improve the outcome of sepsis by stimulating innate immunity in combination with modulating the severity of inflammatory responses in rats. …”
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Pharmacognostic analysis and antimalarial evaluation of quercetin in Ilex umbellulata bark using HPTLC, in vitro screening, molecular docking, and network pharmacology by James H. Zothantluanga, Dipak Chetia, Yasangam Umbon, T. C. Lalhriatpuii, Dhritiman Roy, Nidahun Lamare, Salem Lalvenhimi

“…Despite its traditional relevance, the pharmacognostic parameters and pharmacological properties remained unexplored. In this study, we aim to develop the missing pharmacognostic parameters with modern analytical techniques and carry out multi-step computational studies to study the antimalarial potential of I. umbellulata. …”
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Monitoring Moso bamboo (Phyllostachys pubescens) forests damage caused by Pantana phyllostachysae Chao considering phenological differences between on-year and off-year using UAV h... by Anqi He, Zhanghua Xu, Yifan Li, Bin Li, Xuying Huang, Huafeng Zhang, Xiaoyu Guo, Zenglu Li

“…This study utilizes the Recursive Feature Elimination (RFE) algorithm to investigate hyperspectral remote sensing characteristics of P. phyllostachysae in Moso bamboo forests. We analyzed the impact of on-year and off-year phenological characteristics on the accuracy of hazard extraction and developed detection models for P. phyllostachysae hazard levels in on-year and off-year Moso bamboo using Support Vector Machine (SVM), Random Forest (RF), eXtreme Gradient Boosting (XGBoost), and one-dimensional Convolutional Neural Network (1D-CNN). …”
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Attenuated titin protein expression is associated with advanced stages of ovarian cancer by Harvey Sharma, Jaskaran Aujla, Asad Nawaz, Thabet Khasawneh, Ayesha Alvero, Robert T. Morris, Asma Basha, Laila Tutunji, Toshima Z. Parris, Khalil Helou, Ghassan M. Saed

“…This study explores the role of titin, a giant muscle protein, in the progression of epithelial ovarian cancer (EOC). We examined titin levels in tissues and sera from EOC patients across stages I–IV and in chemoresistant EOC cells. …”
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Development of <i>Aspergillus oryzae</i> BCC7051 as a Robust Cell Factory Towards the Transcriptional Regulation of Protease-Encoding Genes for Industrial Applications by Sarocha Panchanawaporn, Chanikul Chutrakul, Sukanya Jeennor, Jutamas Anantayanon, Kobkul Laoteng

“…Enzyme-mediated protein degradation is a major concern in industrial fungal strain improvement, making low-proteolytic strains preferable for enhanced protein production. Here, we improved food-grade <i>Aspergillus oryzae</i> BCC7051 by manipulating the transcriptional regulation of protease-encoding genes. …”
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Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms by Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu

“…Key Scientific Concepts of Review: This review is focused on three key notions: Firstly, gut microbiota has become a new target for regulating health status and lifespan, and its changes are closely related to age. Thus, we summarized aging-associated gut microbiota features at the levels of key genus/species and important metabolites through comparing the microbiota differences among centenarians, elderly people and younger people. …”
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Association of baseline and trajectory of triglyceride-glucose index with the incidence of cardiovascular autonomic neuropathy in type 2 diabetes mellitus by Qiong Huang, Wenbin Nan, Baimei He, Zhenhua Xing, Zhenyu Peng

“…Subgroup analysis was used to assess the robustness of the results. Additionally, we explored the impact of intensive glycemia treatment on the relationship between trajectory of TyG index and CAN risk. …”
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Prolonged ICU Stay in Severe and Critically-Ill COVID-19 Patients Who Received Convalescent Plasma Therapy by Bambang Pujo Semedi, Nadya Noor Ramadhania, Betty Agustina Tambunan, Siprianus Ugroseno Yudho Bintoro, Soedarsono Soedarsono, Cita Rosita Sigit Prakoeswa

“…Data of all severe and critically-ill patients in our COVID-19 ICU was collected retrospectively between May and November 2020. We dichotomized the variables and compared outcome data of 48 patients, who received convalescent plasma to 131 patients, receiving standard of care. …”
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Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [13C]bicarbonate metabolism in mice by Maiko Ono, Rena Kono, Kosei Hirata, Kosei Hirata, Keita Saito, Motonao Nakao, Yoichi Takakusagi, Rikita Araki, Akira Sumiyoshi, Yuhei Takado

“…In studies of the mouse brain using hyperpolarized [1-13C]pyruvate, there are few reports that the signal of [13C]bicarbonate, a product of oxidative phosphorylation metabolized from [1-13C]pyruvate, was detected using MR spectroscopic imaging (MRSI) that allows spatial mapping of metabolism, although there have been reports of [13C]bicarbonate signals being detected by pulse-acquire sequences in the entire brain. In the present study, we compared hyperpolarized [1-13C]pyruvate metabolism between the brains of awake and isoflurane-anesthetized mice using a custom-made awake mouse restraint device with MRSI. …”
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A density functional theory investigation of the substituent effect on acyclovir and guanine derivatives for applications on energetic materials by Luciana Amorim da Silva, Gabriel Monteiro-de-Castro, Erick Braga Ferrão Galante, Itamar Borges Jr, Aline Cardoso Anastácio

“…Among the molecules with no bridge groups, we found that, except for cyano group, position 4 were the most stable for acyclovir derivatives, whereas, except for the azido group, position 2 and 5 provided the most stable compounds for guanine derivatives. …”
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Do serial troponins predict the need for cardiac evaluation in trauma patients after ground-level fall? by Rachael A Callcut, Alyssa R Bellini, James T Ross, Madelyn Larson, Skyler Pearson, Anamaria J Robles

“…However, the high sensitivity of the test may lead to repeat testing that is of little clinical value. Here, we examine the role of serial troponins in predicting the need for further cardiac workup in trauma patients after sustaining a fall.Methods Retrospective review of all adult trauma activations for ground-level fall from January 1, 2021 to December 31, 2021 in patients who were hemodynamically and neurologically normal at presentation. …”
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Automating airborne pollen classification: Identifying and interpreting hard samples for classifiers by Manuel Milling, Simon D.N. Rampp, Andreas Triantafyllopoulos, Maria P. Plaza, Jens O. Brunner, Claudia Traidl-Hoffmann, Björn W. Schuller, Athanasios Damialis

“…To shed some light on this issue, we conducted a sample-level difficulty analysis based on the likelihood for one of the largest automatically-generated datasets of pollen grains on microscopy images and investigated the reason for which certain airborne samples and specific pollen taxa pose particular problems to deep learning algorithms. …”
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Optimizing Obstructive Sleep Apnea Risk Assessment in Hypertension: Development of a Predictive Nomogram in China by Yang Y, Sun X, Liang J, Liao WF, Ye W, Zheng Z, Du L, Chen M, Zhang Y, Lin W, Huang J, Yao W, Chen R

“…Based on LASSO and Logistic regression analyses and clinical practicality, we identified gender, age, BMI (body mass index), NC (neck circumference) and ESS (Epworth Sleepiness Scale) as predictors for the nomogram. …”
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Analysis of Lens Thickness Distribution Based on Swept-Source Optical Coherence Tomography (SS-OCT) by Xi Feng, Yong Wang, Jianheng Liang, Yali Xu, Julio Ortega-Usobiaga, Danmin Cao

“…Among Chinese age-related cataract patients, we found LT to have the strongest relation with ACD. …”
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Association between ABCB4 variants and intrahepatic cholestasis of pregnancy by Dekun Zhang, Yuhong Li, Shufeng He, Jing Shu, Tiechen Li, Qing Sun

“…The occurrence of intrahepatic cholestasis of pregnancy(ICP) is closely related to ABCB4 variants, but there is limited research on this topic in southern Anhui, China. We sequenced ABCB4 in pregnant women with ICP and healthy pregnant women to explore the relationship. …”
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