Impacted lower third molar classification and difficulty index assessment: comparisons among dental students, general practitioners and deep learning model assistance by Paniti Achararit, Chawan Manaspon, Chavin Jongwannasiri, Promphakkon Kulthanaamondhita, Chumpot Itthichaisri, Soranun Chantarangsu, Thanaphum Osathanon, Ekarat Phattarataratip, Kraisorn Sappayatosok

“…The aim of this study was to evaluate the effectiveness of a convolutional neural network (CNN) in determining the angulation, position, classification and difficulty index (DI) of ILTM. Additionally, we compared these parameters and the time required for interpretation among deep learning (DL) models, sixth-year dental students (DSs), and general dental practitioners (GPs) with and without CNN assistance. …”
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Phylogeography and population structure of the global, wide host-range hybrid pathogen Phytophthora × cambivora by Martin S. Mullett, Kris Van Poucke, Annelies Haegeman, Fran Focquet, Nicholas C. Cauldron, Brian J. Knaus, Marilia Horta Jung, Koji Kageyama, Ayaka Hieno, Hayato Masuja, Seiji Uematsu, Joan F. Webber, Clive M. Brasier, József Bakonyi, Kurt Heungens, Niklaus J. Grünwald, Thomas Jung

“…It was one of the first damaging invasive Phytophthora species to be introduced to Europe and North America, although its origin is unknown. We determined its population genetic history in Europe, North and South America, Australia and East Asia (mainly Japan) using genotyping-by-sequencing. …”
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Sistem Identifikasi Kesehatan Berdasarkan Detak Jantung, Kadar Oksigen, dan Suhu Tubuh Menggunakan Metode Fuzzy Mamdani by Arsal Wildan Naviaddin, Barlian Henryranu Prasetio, Rakhmadhany Primananda

“…Therefore, in this paper we offer an effective and efficient approach in early detection of health. …”
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Apical transportation of nickel titianium reciprocating instruments. An in vitro study by Dario Di Nardo, Massimo Galli, Morgana Foghetti, Almira Isufi, Ivana Vidovic, Tugba Turk, Gabriele Miccoli

“…Conclusions: From the examination of the data obtained in this experimental thesis, we conclude that all three types of instruments analyzed can lead to alterations in the original anatomy when operated inside a curved canal. …”
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Canine distemper outbreak and laryngeal paralysis in captive tigers (Panthera tigris) by Sarin Suwanpakdee, Anuwat Wiratsudakul, Nattarun Chaisilp, Luxsana Prasittichai, Anurux Skulpong, Patarapol Maneeorn, Benjaporn Bhusri, Chalisa Mongkolpan, Ruangrat Buddhirongawatr, Jarupa Taowan, Peerawat Wongluechai, Nlin Arya, Parin Suwannaprapha, Natharin Ngamwongsatit, Witthawat Wiriyarat, Nareerat Sangkachai

“…This study aimed to understand better the burden of CDV outbreaks in captive tiger populations in Thailand and a novel discovery of their clinical signs with a history of CDV exposure. We followed up on their infection from May 2016 to October 2020 with laboratory testing and veterinary medical records. …”
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Th2-Immune Polarizing and Anti-Inflammatory Properties of Insulin Are Not Effective in Type 2 Diabetic Pregnancy by Adnette Fagninou, Magloire Pandoua Nekoua, Darius Sossou, Kabirou Moutairou, Nadine Fievet, Akadiri Yessoufou

“…The implication of the immune system in the physiopathology of pregnancy complicated by diabetes has been reported. Here, we investigated the effects of insulin treatment on the frequencies of immune cell subpopulations as well as T cell-derived cytokines in type 2 diabetic (T2D) pregnancy compared to gestational diabetes mellitus (GDM). …”
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Case Report: Diagnostic itinerary of a male case of juvenile-onset systemic lupus erythematosus in Bouake by Aissata Doucoure Traore, Aissata Doucoure Traore, Joseph Kan Enock Koffi, Joseph Kan Enock Koffi, Christ Ziahy Reine Marie Koffi, Christ Ziahy Reine Marie Koffi, Konan Joe Clovis Yao, Konan Joe Clovis Yao, Jean Jacque Goua, Jean Jacque Goua, Ehaulier Soh Christian Kouakou, Ehaulier Soh Christian Kouakou, Weu Melanie Tia, Weu Melanie Tia, Felix Jean Claude Daboiko, Felix Jean Claude Daboiko

“…It is a polymorphous condition, misleading at first and little known in our African populations. We report a case of 12 years of misdiagnosis in a 17-year-old boy living in a semi-rural environment. …”
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Rab21-Targeted Nano Drug Delivery System-Based FFPG for Efficient Paclitaxel Delivery to Inhibit Lung Cancer Progression by Jing Wang, Xueying Yan, Wenfei Wang, Shu Wang, Hongxiang Jiang, Xinhua Zhu, Zhehui Li, Defu Cai, Yonggang Xia

“…Inspired by the mechanism and our previous finding about fructans and fructooligosaccharides from <i>Platycodon grandiflorus</i> (FFPG), we developed a nano drug delivery system (NDDS) targeting lung cancer. …”
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The use of bacterial culture for Leptospirosis di- agnosis in female water buffaloes by Rosaura Pérez-Gil, Oriana Gavidia, Juan Torres

“…Additionally, these preliminary findings confirm Leptospira is an agent involved in abortions, as we obtained Leptospira spp. growth from aborted fetus samples. …”
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Human Factors Studies to Assess the Usability of the Faricimab Prefilled Syringe by Barakat MR, Kwong Jr HM, Marcon G, O'Leary OE, Paris LP, Schneider P, Tang Y, Graff JM

“…., San Francisco, CA, USA; 6Barnet Dulaney Perkins Eye Center, Phoenix, AZ, USA; 7Ophthalmology Division, Creighton University School of Medicine, Phoenix, Arizona, USACorrespondence: Jordan M Graff, Barnet Dulaney Perkins Eye Center, Phoenix, AZ, USA, Tel +1 480 843 1868, Email JGraff@BDPEC.comPurpose: Faricimab, the first bispecific antibody designed for intraocular use, is approved for the treatment of neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO). Here, we report the usability of a novel faricimab 6 mg pre-filled syringe (PFS) configuration that has been designed specifically for intravitreal use.Patients and Methods: A simulated-use human factors validation study enrolling 15 retina specialists and 15 ophthalmic assistants was conducted in a market research facility configured to represent an ophthalmology clinic. …”
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Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella by Devon W. Kavanaugh, Adeline Sivignon, Yannick Rossez, Zina Chouit, Christophe Chambon, Christophe Chambon, Louane Béal, Mathilde Bonnet, Michel Hébraud, Michel Hébraud, Yann Guérardel, Hang Thi Thu Nguyen, Nicolas Barnich

“…Using biochemical and glycobiological techniques, including biotin-hydrazide labeling of glycans and chemical and glycosidase treatments, we demonstrate (i) the presence of a well-defined and chemically resistant FimA oligomer in several strains of pathogenic and non-pathogenic E. coli, (ii) the major subunit of type I fimbriae, FimA, in pathogenic and laboratory strains is recognized by concanavalin A, (iii) standard methods to remove N-glycans (PNGase F) or a broad-specificity mannosidase fail to remove the glycan structure, despite the treatments resulting in altered migration in SDS-PAGE, (iv) PNGase F treatment results in a novel 32 kDa band recognized by anti-FliC antiserum. …”
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Ammonifying and phosphorus-solubilizing function of Aliikangiella maris sp. nov. isolated from Phaeocystis globosa bloom and algal–bacterial interactions by Fei Li, Fei Li, Ming-Ben Xu, Liang-Hao Pan, Jie Li, Cai-Bi Lan, Zhe Li, Shan Lu, Jun-Xiang Lai, Jun-Xiang Lai, Peng-Fu Li

“…Emerging evidence indicates that algae–bacterial interactions play pivotal roles in shaping the ecology and evolution of harmful algal blooms, although much of this interplay remains unexplored. We successfully isolated and propagated two novel bacterial strains from Phaeocystis globosa bloom. …”
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Socio-economic inequalities in access to COVID-19 tests in France in 2020: evidence from the EPICOV socio-epidemiological cohort by Pierre-Yves Geoffard, Pierre-Yves Geoffard, Florence Jusot, Antoine Sireyjol, Josiane Warszawski, Nathalie Bajos

“…Our main objective was to investigate whether access to COVID-19 testing in France was associated with socio-economic conditions, considering gender and ethno-racial status.MethodsA random population-based cohort survey was conducted in France in May 2020 and November 2020, including 95,388 participants aged 18 and over. We used logistic regressions to identify how having been tested in 2020 was associated with socio-economic status and exposure factors among two groups of individuals. …”
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Klasifikasi Laporan Keluhan Pelayanan Publik Berdasarkan Instansi Menggunakan Metode LDA-SVM by Muhammad Alkaff, Andreyan Rizky Baskara, Irham Maulani

“…However, the increasing volume of reports and the sorting of reports carried out by operators by reading every complaint that comes through the system cause frequent errors where operators forward the reports to the wrong agencies. Therefore, we need a solution that can automatically determine the report's context using Natural Language Processing techniques. …”
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Postprogression therapy and confounding for the estimated treatment effect on overall survival in phase III oncology trials by Pavlos Msaouel, Ramez Kouzy, Joseph Abi Jaoude, Ethan B Ludmir, Alexander D Sherry, Timothy A Lin, Esther J Beck, Avital M Miller, Adina H Passy, Gabrielle S Kupferman, Eugene J Koay, Clifton David Fuller, Charles R Thomas, Zachary R McCaw

“…The purpose of this cross-sectional analysis was to determine the prevalence of OS analyses accounting for PPT effects in phase III oncology trials.Methods and analysis We screened two-arm, superiority design, phase III, randomised, oncology trials reporting OS from ClinicalTrials.gov. …”
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Designing a Stock Recommender System Using the Collaborative Filtering Algorithm for the Tehran Stock Exchange by Marziyeh Nourahmadi, Ali Rahimi, Hojjatollah Sadeqi

“…In this research, assuming the existence of the transmission effect on the Tehran Stock Exchange, we used the collaborative filtering technique, a common algorithm in recommender systems, to design a stock recommender system. …”
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De la neuroplasticidad a las propuestas aplicadas: estimulación temprana y su implementación en Costa Rica / From Neuroplasticity to Applied Proposals: Early Stimulation and Its Im... by Johanna Sibaja-Molina, Tracy Sánchez-Pacheco, Mijail Rojas-Carvajal, Jaime Fornaguera-Trías

“…Finally, bringing up the scope and limitations of ES, we conclude that the professional experiences need to be systematized, in order to open an academic debate on the subject. …”
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Perception of phage therapy and research across selected professional and social groups in Poland by Maciej Żaczek, Marcin W. Zieliński, Andrzej Górski, Andrzej Górski, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki

“…With the COVID-19 pandemic in the background, we also explored how the pandemic influenced the interest in experimental therapies in general, which makes this article a potential universal compendium on perceptions of experimental therapies in the coming years.…”
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RHO Mutations (p.W126L and p.A346P) in Two Japanese Families with Autosomal Dominant Retinitis Pigmentosa by Satoshi Katagiri, Takaaki Hayashi, Masakazu Akahori, Takeshi Itabashi, Jo Nishino, Kazutoshi Yoshitake, Masaaki Furuno, Kazuho Ikeo, Tetsuji Okada, Hiroshi Tsuneoka, Takeshi Iwata

“…Results. In two adRP families, we identified two RHO mutations (c.377G>T (p.W126L) and c.1036G>C (p.A346P)), one of which was novel. …”
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Neoadjuvant Immunotherapy and De-escalation of Surgery in Locally Advanced Breast Implant-associated Anaplastic Large Cell Lymphoma by Marzia Salgarello, Jaroslaw Krupa, Rebecca Allchin, Simon Pilgrim, Fiona Miall, Arianna Di Napoli, Maurizio Martelli, Giulio Tarantino

“…Due to the complex nature of this disease, a multidisciplinary approach is necessary for optimal management, particularly in locally advanced disease or inoperable patients. We present the successful use of neoadjuvant therapeutic protocols in two cases of locally advanced BIA-ALCL. …”
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