Replication Study of “Visual Fixation on the Thorax Predicts Bystander Breathing Detection in Simulated Out-of-Hospital Cardiac Arrest” by Marco Pedrotti

“…., a victim who is unresponsive and not breathing, is essential to begin CPR as soon as possible. In 2022, we published a simulation study (Study 1; n = 96)which found that instructing lay responders to look at chest movement enables them to detect breathing. …”
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Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster by Ren-Di Jiang, Yun-Zhe Luo, Hao-Feng Lin, Xiao-Shuang Zheng, Wen-Tao Zeng, Mei-Qin Liu, Hao-Hao Deng, Qi Wang, Ya-Na Lai, Ying Chen, Zi-Shuo Guo, Ya Zeng, Qian-Chun Gong, Chen Qiu, Mei Dong, Xi Wang, Zi-Yi Wang, Li-Na Ji, Pan-Pan Hou, Qian Li, Xu-Rui Shen, Bei Li, Yun Gao, Ai-Hua Zhang, Ting-Ting Jiang, Ai-Min Shi, Peng Zhou, Xin-Hua Lin, Zi-Qing Deng, Jian-Min Li, Zheng-Li Shi

“…However, the mechanisms underlying severe illnesses in individuals with obesity are poorly understood. Here, we used gene-edited leptin knock out (Leptin−/−) obese hamsters to establish a severe infection model. …”
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INTERNATIONAL FORUM OF AMERICAN SOCIETY FOR ENGINEERING EDUCATION by Vasily Ivanov, Yulia Ziyatdinova

“…The President of SEFI Kamel Hawwash gave a verydetailed report on European engineering education stressing that the global crisis that we face is the crisis in engineering competencies, which do not satisfy the requirements of the employers. …”
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Clinicians’ user experience with health information exchange technologies during simulated medication reconciliation by Himalaya Patel, April Savoy, Steven L. Sanchez, Morgan Traylor, Khoa A. Nguyen, Kenneth S. Boockvar, Vincent S. Fan, Emily R. Locke, Bryan Gibson, Amanda S. Mixon, Susan H. Byerly, David A. Haggstrom, Teresa M. Damush, Michael Weiner, Alissa L. Russ-Jara

“…To ease coding, we used problem frequency to indicate severity. …”
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Gestational exposure to arsenic reduces female offspring fertility by impairing the repair of DNA double-strand breaks and synapsis formation in oocytes by Cong Ma, Kaiqin Hu, Xueke Zhang, Yaru Yu, Zuying Xu, Tian Ma, Hongzhen Ruan, Yingying Zhang, Jiajia Wang, Xinyu Yue, Chunmei Liang, Huifen Xiang, Rui Guo, Yunxia Cao, Zhiming Ding

“…By assessing the in vitro developmental capacity of oocytes and zygotes, we confirmed that the reduced fertility was due not to impaired oocyte quality but rather to a reduction in oocyte quantity. …”
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Dietary protein intake and PM2.5 on ovarian cancer survival: A prospective cohort study by He-Li Xu, Yi-Fan Wei, Qi Bao, Ya-Li Wang, Xiao-Ying Li, Dong-Hui Huang, Fang-Hua Liu, Yi-Zi Li, Yue-Yang Zhao, Xin-Xin Zhao, Qian Xiao, Song Gao, Ren-Jie Chen, Ling Ouyang, Xia Meng, Xue Qin, Ting-Ting Gong, Qi-Jun Wu

“…By assessing the relative excess risk due to interaction (RERI) arising from the interplay between PM2.5 exposure and dietary protein intake, we explored the additive interaction between the two. …”
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Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study by Patrice Cacoub, Arsène Mekinian, David Saadoun, Pavel I Novikov, Savino Sciascia, Corrado Campochiaro, Olivier Fain, Ilya Smitienko, Nicolas Schleinitz, Patrick Jégo, Francesco Muratore, Carlo Salvarani, Elena Galli, Sabine Berthier, Marc Lambert, François Maurier, Isabelle Kone-Paut, Sergey Moiseev, Masataka Kuwana, Alexandre Belot, Martin Michaud, Francis Gaches, Achille Aouba, Xavier Puechal, Karim Sacre, Tiphaine Goulenok, Alessandro Tomelleri, Thomas Sené, Elena Marina Baldissera, Luigi Boiardi, Abid Awisat, Ygal Benhamou, Vahan Mukuchyan, Mathieu Vautier, Azeddine Dellal, Lucie Biard, Julie Seguier, José Hernández-Rodríguez, Olivier Espitia, Sebastien Humbert, Guillaume Denis, Nolan Hassold, Dagna Lorenzo, Helene Munoz Pons, Jean Baptiste Gaultier, Le Mouel Edwige, Antoinette Perlat, Bertrand Lioger, Jonathan Broner, Virginie Dufrost, Faten Frikha, Alexandra Audemard-Verger, Pascal Woaye-Hune, Pierre Zeminsky, Moya Alvarado, Matheus Vieira, Alberto Lo Gullo

“…Objectives In this large multicentre study, we compared the effectiveness and safety of tocilizumab intravenous versus subcutaneous (SC) in 109 Takayasu arteritis (TAK) patients.Methods We conducted a retrospective multicentre study in referral centres from France, Italy, Spain, Armenia, Israel, Japan, Tunisia and Russia regarding biological-targeted therapies in TAK, since January 2017 to September 2019.Results A total of 109 TAK patients received at least 3 months tocilizumab therapy and were included in this study. …”
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CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

“…Several treatments (eg, chemotherapy, surgery, radiations, hormonal therapy, etc.) are conventionally prescribed for the treatment of BC; however, these are associated with serious systemic aftermaths. In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. …”
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Categorising implementation determinants and strategies within the US HIV implementation literature: a systematic review protocol by Justin D Smith, Brian Mustanski, Virginia McKay, James Lorenz Merle, Dennis Li, Brennan Keiser, Alithia Zamantakis, Artur Queiroz, Carlos G Gallo, Juan A Villamar, Juan Pablo Zapata, Nanette Benbow

“…Articles were eligible for inclusion if they were: conducted in the USA, published after the year 2000, written in English, related to HIV/AIDS, focused on outcomes related to dissemination and implementation (ie, did not test/evaluate/explore implementation determinants or strategies) and were behavioural studies (ie, not basic science). We plan to conduct three systematic reviews to identify and categorise determinants and strategies associated with three HIV focus areas: pre-exposure prophylaxis, testing/diagnosing and linkage to care, and treatment. …”
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Oxamflatin and ascorbic acid improves developmental competence and quality of buffalo (Bubalis bubalis) cloned embryos by Sonal Gupta, Gaurav Tripathi, Kartikey Patel, Ram Parsad, Tanya Gupta, Naresh L. Selokar, Manoj Kumar Singh

“…Aberrant epigenetic marks can be modified by culturing donor cells and/or one cell stage fused embryo or both with epigenetic modifiers alone or in combination. In the present study, we examined the effect of oxamflatin (OxF), ascorbic acid (AA), and their combined (OxF+AA) effect on in vitro developmental competence, quality, and pregnancy establishment rate of buffalo cloned embryos. …”
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Efficacy Analysis of Percutaneous Endoscopic Lumbar Discectomy Combined with PEEK Rods for Giant Lumbar Disc Herniation: A Randomized Controlled Study by Xiang Gao, Kaiying Tang, Yu Xia, Xun Zhang, Keran Wang, Zhengjian Yan, Yu Du, Liang Chen

“…Maximum benefit can be gained if we adhere to strict selection criteria for PELD combined with a PEEK rod.…”
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Over 20-year Follow-up Result of Total Knee Arthroplasty for Knee Arthropathy: A Single Center Cohort Study by XU Yiming, HU Mingwei, ZHU Wei, YU Muyang, LIN Jin, JIN Jin, QIAN Wenwei, FENG Bin, WENG Xisheng

“…ObjectiveTo evaluate long-term survival and clinical outcomes of patients with knee osteo-arthritis undergoing total knee arthroplasty (TKA) through long-term follow-up.MethodsThis study was based on a previous cohort study that had completed follow-up. We retrospectively collected clinical data of patients with knee arthropathy (including knee osteoarthritis and knee rheumatoid arthritis) who received the first TKA operation in Peking Union Medical College Hospital from 1993 to 2002 and were followed up for more than 20 years, and conducted a unified follow-up on them in November 10, 2024 (the last follow-up). …”
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Acute-on-Chronic Liver Failure in Pregnant Patients with Chronic Hepatitis B: A Retrospective Observational Case Series Study by Shiwei Wang, Haofeng Xiong, Changling Luo, Hong Zhao, Ying Fan, Ting Zhang, Lili Wang, Qi Wang, Wen Xie

“…This study retrospectively reviewed five patients who were diagnosed with ACLF during pregnancy in the past 10 years. We aimed at investigating their clinical characteristics, treatment, biochemical test results, and maternal and fetal outcomes. …”
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Associations between CAG repeat size, brain and spinal cord volume loss, and motor symptoms in spinocerebellar ataxia type 3: a cohort study by Zhi-Xian Ye, Xuan-Yu Chen, Meng-Cheng Li, Xin-Yuan Chen, Yu-Sen Qiu, Ru-Ying Yuan, Zhi-Li Chen, Min-Ting Lin, Jian-Ping Hu, Ying Fu, Wan-Jin Chen, Ning Wang, Shi-Rui Gan, on behalf of the OSCCAR Investigators

“…Methods In this prospective, cross-observational study, we analyzed 3D T1-weighted MRIs from 92 patients with SCA3 and 42 healthy controls using voxel-based morphometry and region of interest approaches. …”
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Postpartum depression in relation to chronic diseases and multimorbidity in women’s mid-late life: a prospective cohort study of UK Biobank by Yue Zhang, Yangyang Cheng, Rodrigo M. Carrillo-Larco, Yaguan Zhou, Hui Wang, Xiaolin Xu

“…Chronic diseases also accumulated at a faster annual rate for women with a history of PPD (b = 0.009, 95% CI = 0.007–0.011), compared to those without. We observed no interaction or mediation effects of physical activity, smoking, alcohol drinking, and dietary factors on the association between PPD and multimorbidity; however, women’s body mass index at baseline contributed to the association, with the mediation proportion of 6.38% (2.56–10.20%). …”
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Adherence to face mask use during the COVID-19 pandemic among women seeking antenatal care in Kinshasa, Democratic Republic of Congo: a facility-based cross-sectional study by Steven Anderson, Dalau Mukadi Nkamba, Patrick J Arena, Adva Gadoth, Nicole A Hoff, Camille Dzogang, David Kampilu, Michael Beya, Hui-Lee Wong, Didine Kaba, Anne W Rimoin

“…Objectives To describe face mask use among pregnant women seeking antenatal care (ANC) in Kinshasa, Democratic Republic of Congo and to identify factors associated with masking adherence in this population.Design Facility-based cross-sectional study nested within a prospective cohort study.Setting Random sample of 10 health facilities, including 5 primary health centers and 5 secondary facilities or hospitals.Participants A total of 934 pregnant women aged 18 years or above with a gestational age of at least 32 weeks were consecutively surveyed from 17 August 2020 to 31 January 2021.Primary and secondary outcome measures We estimated the proportions of pregnant women wearing a face mask and masking correctly (ie, over the mouth and nose), and assessed their knowledge regarding the COVID-19 pandemic. …”
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Challenging cases of adherent periarterial vein during subinguinal Fisch technique and subinguinal micro-varicocelecotmy and sclerotherapy: a prospective comparative study by Amr Elahwany, Nashaat Nabil, Sameh Fayek GamalEl Din, Ahmed Raef Sadek, Ahmed Ewais Sayed, Ahmed Ragab

“…Consequently, leaving the artery intact or ligating it together with the adherent vein may pose a challenge. We conducted a comparative prospective study to assess the outcomes of the three techniques namely Fisch, sclerotherapy and microvaricoclectomy (MSV). …”
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Inferior vena cava diameter in patients with chronic heart failure and chronic kidney disease: a retrospective study by Jianan Li, Chi Wang, Hui wu Dong, Jing Qi, Chongyou Rao, Qiuyang Li, Kunlun He

“…Information on all-cause mortality was collected by telephone interview and medical records review. We used Cox regression to evaluate the risk of all-cause mortality among groups, and used mediation analysis to examine the mediation role of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) and serum albumin in the association between IVC and all-cause mortality. …”
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Minimizing Power Consumption and Interference Mitigation of Downlink NOMA HetNets by IRS-Supported Aerial Base Stations by Osamah Thamer Hassan Alzubaidi, Mhd Nour Hindia, Kaharudin Dimyati, Kamarul Ariffin Noordin, Faizan Qamar, Atef Abdrabou

“…Intelligent reflection surface (IRS) is an advanced technology that effectively transforms the wireless propagation environment to next-generation wireless networks. In this paper, we employ the IRS-supported multi-aerial base station (ABS) in a downlink non-orthogonal multiple access (NOMA) heterogeneous network (HetNets), where the transmission signals from multiple ABSs to ground users (GUs) are enhanced using the IRS. …”
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Understanding how older people with mild frailty engage with behaviour change to support their independence: a qualitative study by Benjamin Gardner, Louise Marston, Kate R Walters, Vari M Drennan, Rachael Frost, Paul Chadwick, Rebecca L Gould, Yolanda Barrado-Martin, Sarah Gibson, Rekha Elaswarapu, Rashmi Kumar, Kalpa Kharicha, Tasmin Alanna Rookes, Christina Avgerinou, Jane Hopkins, Jessica Catchpole, Claire Jowett

“…Objectives To explore barriers and facilitators to behaviour change in older people with mild frailty.Design Qualitative study.Setting Community-dwelling older people living with mild frailty.Participants 64 older people with mild frailty, workers delivering the service and stakeholders.Methods Semistructured interviews were conducted between July 2022 and May 2023 with participants in a randomised controlled trial (‘HomeHealth’) of a 6-month, home-based, personalised goal setting intervention, based around the Capability-Opportunity-Motivation-Behaviour model. We purposively sampled older participants receiving the service (n=49), workers delivering it (n=7) and stakeholders supporting its delivery (n=8). …”
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