A20 as a Potential Therapeutic Target for COVID‐19 by Yongyao Wu, Lilan He, Rong Li, Jiuxuan Li, Qing Zhao, Bin Shao

“…Methods This narrative literature review summarizes recent evidence on the mechanisms of A20 in regulating the pathological processes of COVID‐19. We also downloaded single‐cell RNA‐seq data sets from healthy individuals and patients with varying severities of COVID‐19 from the NCBI GEO database to further dissect A20's regulatory mechanisms of these intricate cytokine pathways that are closely associated with SARS‐CoV‐2 infection. …”
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Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Nondialysis Chronic Kidney Patients by Gysllene M. C. Brito, Andrea M. M. Fontenele, Erika Cristina R. L. Carneiro, Iara Antonia L. Nogueira, Tamires B. Cavalcante, André A. M. Vale, Sally Cristina M. Monteiro, Natalino Salgado Filho

“…The Neutrophil-to-Lymphocyte Ratio (NLR) and the Platelet-to-Lymphocyte Ratio (PLR) are inflammatory biomarkers for several diseases, such as cancer and cardiovascular morbidities; however, there are currently few studies on kidney diseases. We aimed to evaluate nondialysis patients and determine the association of NLR and PLR with inflammation in these patients. …”
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Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study by Fattaneh Pahlavan, Shohreh Irani, Mehri Mashayekhi, Samira Vesali, Fatemeh Niknejad, Firoozeh Ahmadi, Narges Bagheri-Lankarani

“…A T-shaped uterus might be related to poor reproductive outcomesor pregnancy complications. We aim to compare the success rates of in vitro fertilization (IVF) between individualswith a normal uterus and those with a T-shaped uterus identified through Hysterosalpingography.Materials and Methods: A retrospective cohort study was done in Royan Institute, Iran, in April 2020-April 2021.In line with the criteria for inclusion and exclusion, 468 cases were selected. …”
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C-Reactive Protein in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy and Relationship with Ventricular Tachycardia by Aimé Bonny, Nicolas Lellouche, Ivo Ditah, Françoise Hidden-Lucet, Martial T. Yitemben, Benjamin Granger, Fabrice Larrazet, Robert Frank, Guy Fontaine

“…In ARVD/C patients with VT, we analyzed the association between VT occurrences and CRP level. …”
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Soil microbial community and influencing factors of different vegetation restoration types in a typical agricultural pastoral ecotone by Pei Huang, Pei Huang, Pei Huang, Hanyu Shi, Hanyu Shi, Lina Jiang, Duoping Zhu, Duoping Zhu, Zefeng Zhou, Zhenhong Hou, Xingyu Ma, Xingyu Ma

“…Therefore, in this study, we selected four vegetation restoration types (Pinus sylvestris var. mongholica, Larix principis- rupprechtii, Populus tomentosa, and Ulmus pumila), while selected the nature grassland as a control, in the Zhangjiakou Tunken Forest Farm, which is a typical agricultural pastoral ecotone in northern China, to investigate the response of soil microbial diversity and network complexity to different vegetation restoration types. …”
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Injectable iodine-containing peptide hydrogel for treatment of MRSA infection by Yu Zhang, Haiyan Liu, Weiqi Zhang, Yinghao Ding, Shengyi Zhang, Xiaowan Huang, Jiali Chen, Zhimou Yang, Feng Lin

“…However, its clinical utility is often hampered by its unsatisfactory stability, uncontrolled release of active iodine and toxicity in moist environments. In this study, we report a novel iodine-containing hydrogel (I2@Nap-FFGP) designed for sustained iodine delivery under humid physiological and pathological conditions. …”
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Psychological responses to acute exercise in patients with stress-induced exhaustion disorder: a cross-over randomized trial by Jenny Kling, Robert Persson Asplund, Örjan Ekblom, Victoria Blom

“…Aims This study aims to (1) compare the psychological responses to acute exercise between ED patients and healthy controls and (2) assess response differences between low and moderate exercise intensities. Methods We conducted a two-armed cross-over trial comparing ED patients (n = 30) and healthy controls (n = 30). …”
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Comparison of Mortality Risk Models in Patients with Postcardiac Arrest Cardiogenic Shock and Percutaneous Mechanical Circulatory Support by Georgios Chatzis, Birgit Markus, Styliani Syntila, Christian Waechter, Ulrich Luesebrink, Holger Ahrens, Dimitar Divchev, Bernhard Schieffer, Konstantinos Karatolios

“…Although scoring systems are widely used to predict outcomes in postcardiac arrest cardiogenic shock (CS) after out-of-hospital cardiac arrest (OHCA) complicating acute myocardial infarction (AMI), data concerning the accuracy of these scores to predict mortality of patients treated with Impella in this setting are lacking. Thus, we aimed to evaluate as well as to compare the prognostic accuracy of acute physiology and chronic health II (APACHE II), simplified acute physiology score II (SAPS II), sepsis-related organ failure assessment (SOFA), the intra-aortic balloon pump (IABP), CardShock, the prediction of cardiogenic shock outcome for AMI patients salvaged by VA-ECMO (ENCOURAGE), and the survival after venoarterial extracorporeal membrane oxygenation (SAVE) score in patients with OHCA refractory CS due to an AMI treated with Impella 2.5 or CP. …”
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Increased birth rank of homosexual males: disentangling the older brother effect and sexual antagonism hypothesis by Raymond, Michel, Turek, Daniel, Durand, Valérie, Nila, Sarah, Suryobroto, Bambang, Vadez, Julien, Barthes, Julien, Apostolou, Menelaos, Crochet, Pierre-André

“…To clarify this situation, we developed theoretical and statistical tools to study FBOE and AE independently or in combination, taking into account all known sampling biases. …”
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Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model by Samy Zaky, Mohamed Elbadry, Maysaa A. Saeed, Hanaa Fathelbab, Fatma Abdelsalam, Mohammed Gamal Abdel-Hamid, Alshaimaa Eid, Asmaa Bakr, Amira Maher, Mona Mohammed Abdelrahman, Mohamed A. Metwally, Mahmoud Saad Berengy, Enaam Ali AlMowafy, Hassan Goabar, Amin Abdel Baki, Ahmed Corie, Osama Hammad, Entesar Elsharkawy, Ahmed Saad, Fatma Ali-Eldin, Ahmed Mahdy, Ramadan Zaky, Reham Hammad, Gamal Essmat

“…Rapid intervention in such cases is mandatory, which is not easy in countries with limited income due to weak capabilities and resources. Therefore, we are in dire need of making an Egyptian consensus that suits our country as a low-resource one, in order to facilitate and speed up the process of managing such cases. …”
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P-block element modulated 1 T phase MoS2 with Ru lattice grafting for high-performance Li | |O2 batteries by Peng Wang, Danyang Zhao, Peng Zhang, Xiaobin Hui, Zhiwei Zhang, Rutao Wang, Chengxiang Wang, Xiaoli Ge, Xiaojing Liu, Yuguang C. Li, Longwei Yin

“…To circumvent these issues, here we propose a p-block element (In-O) doping strategy to stabilize the 1 T phase MoS2 by moderating the surface orbital steric effect and strengthening the internal chemical bonding, and thus for the epitaxial Ru nanocatalyst graft on the stabilized 1T-MoS2 for Li | |O2 batteries. …”
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Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β,... by André L. F. Sampaio, Jesmond Dalli, Vincenzo Brancaleone, Fulvio D'Acquisto, Mauro Perretti, Carmen Wheatley

“…However, there has been no in vivo investigation of the (in vitro) •NO scavenger, cobalamin’s (Cbl) endogenous effects on NOS/•NO/inflammatory mediators during the immune response to sepsis. Methods. We used quantitative polymerase chain reaction (qPCR), ELISA, Western blot, and NOS Griess assays, in a C57BL/6 mouse, acute endotoxaemia model. …”
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Renal impairment and in-hospital adverse renal events in critically ill patients assessed by age-adapted estimated glomerular filtration rate criteria by Chong Zhang, Weiru Liang, Meng Ning, Bin Su, Tingting Guo, Kun Hu, Wei Su, Yi Chen, Wenjin Peng, Yingwu Liu

“…Furthermore, the impact of eGFR trajectory changes on in-hospital MARE in this patient population remains underexplored.Methods In this study, we analyzed data from 7,423 critically ill patients using version 2.2 of the Medical Information Mart for Intensive Care IV database. …”
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RETRACTED ARTICLE: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer by Olivia Crociani, Francesca Zanieri, Serena Pillozzi, Elena Lastraioli, Matteo Stefanini, Antonella Fiore, Angelo Fortunato, Massimo D'Amico, Marika Masselli, Emanuele De Lorenzo, Luca Gasparoli, Martina Chiu, Ovidio Bussolati, Andrea Becchetti, Annarosa Arcangeli

“…Abstract Angiogenesis is a potential target for cancer therapy. We identified a novel signaling pathway that sustains angiogenesis and progression in colorectal cancer (CRC). …”
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Determinants of Change in Glycemic Status in Individuals with Prediabetes: Results from a Nationwide Cohort Study in Germany by Rebecca Paprott, Christa Scheidt-Nave, Christin Heidemann

“…Previous studies investigating determinants of changes in glycemic status among individuals with prediabetes mainly focused on glucose-defined prediabetes. In this study, we examined determinants of a regression to normoglycemia or a progression to diabetes among individuals with HbA1c-defined prediabetes. …”
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Differential HLA Association of GAD65 and IA2 Autoantibodies in North Indian Type 1 Diabetes Patients by Neihenuo Chuzho, Neeraj Kumar, Neetu Mishra, Nikhil Tandon, Uma Kanga, Gurvinder Kaur, Paras Singh, Gunja Mishra, Shreya Sharma, Narinder K. Mehra

“…The human leucocyte antigen (HLA) association with type 1 diabetes (T1D) is well known but there are limited studies investigating the association between β-cell autoantibodies and HLA genes. We evaluated the prevalence of GAD65 and IA-2 autoantibodies (GADA and IA2A) in 252 T1D patients from North India and investigated the genetic association of GADA and IA2A with HLA class I and class II genes/haplotypes. …”
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Enhancing phosphorus availability and dynamics in acidic soils through Rice straw biochar application: a sustainable alternative to chemical fertilizers by Wei He, Wei He, Wei He, Jun Zhang, Jun Zhang, Weichun Gao, Weichun Gao, Yifei Chen, Yifei Chen, Zheng Wei, Zheng Wei

“…Using a range of biochar application rates, we examined the effects on phosphorus fractions, phosphatase activity, and microbial biomass phosphorus. …”
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Serum level of soluble interleukin‐2 receptor is positively correlated with metabolic tumor volume on 18F‐FDG PET/CT in newly diagnosed patients with diffuse large B‐cell lymphoma... by Hajime Senjo, Minoru Kanaya, Koh Izumiyama, Koichiro Minauchi, Kenji Hirata, Akio Mori, Makoto Saito, Masanori Tanaka, Hiroaki Iijima, Eriko Tsukamoto, Kazuo Itoh, Shuichi Ota, Masanobu Morioka, Daigo Hashimoto, Takanori Teshima, North Japan Hematology Study Group (NJHSG)

“…In order to explore a surrogate marker for TMTV, we evaluated the correlation between the serum levels of soluble interleukin‐2 receptor (sIL‐2R) and TMTV in 64 patients with DLBCL, and the results were verified in an independent validation cohort of 86 patients. …”
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The Increased Ratio of Blood CD56bright NK to CD56dim NK Is a Distinguishing Feature of Primary Sjögren’s Syndrome by Bingxia Ming, Tong Wu, Shaozhe Cai, Peng Hu, Jungen Tang, Fang Zheng, Cong Ye, Lingli Dong

“…The aim of this study was to characterize the subsets of circulating CD56+ NK cells in pSS patients and their potential value in the diagnosis and/or prediction of prognosis in patients with pSS. Methods. We included 52 pSS patients fulfilling the 2002 AECG criteria or 2012 ACR criteria and 20 age- and gender-matched healthy volunteers. …”
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A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy by Ling Wang, Yuzhong Zhang, Shenglin Geng, Lan Ma, Yiran Wang, Dongxu Han, Guojuan Fan, Weifen Zhang, Weifen Zhang, Weifen Zhang, Yanna Lv, Jinlong Ma, Jinlong Ma, Jinlong Ma

“…Here, based on the theory of Chinese medicines compatibility, we made a purslane-tannic acid hydrogel (PL-HATA) by simple methods under mild conditions to solve the drawbacks of easy oxidation and inconvenience of use of Purslane. …”
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