Characterizing a complex buildup in the Pearl River Mouth Basin of the northern South China Sea: an interplay of carbonates and igneous rocks by Beichen Chen, Leyi Xu, Baojun Liu, Lili Zhang, Dong Xiao, Ya Gao, Ya Gao, Feng Wu, Xueqi Yang, Yaming Zou, Yongkun Ma, Yinglin Zhang

“…The evolution of the buildup is divided into three stages: (1) volcanic eruptions and carbonates development, (2) overflowing magma and reef shoal deposits, and (3) reef-bank deposition accompanied by igneous intrusion. We propose that volcanic rocks can be distinguished from carbonates by the temporal and spatial coupling of typical features: (a) surface volcanic rocks and subsurface intrusive bodies are inseparable, with igneous rocks identifiable through faults and volcanic conduits; (b) carbonates typically display symmetrical structures on both sides of the highland and exhibit better stratification away from igneous activity; (c) carbonates generally show a convex clinoform and steep slope at the platform margin, while volcanic mounds exhibit concave gentle slopes. …”
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Radiological and Clinical Features and Outcomes of Patients with Primary Pulmonary Salivary Gland-Type Tumors by Xiaoyu Han, Jianchu Zhang, Jun Fan, Yukun Cao, Jin Gu, Heshui Shi

“…Materials and Methods. We retrospectively collected clinical and pathological data for 32 SGT cases confirmed by pathology and analyzed their radiological features, clinical presentations, and treatment outcomes. …”
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Constructing benzothiadiazole‐based donor‒acceptor covalent organic frameworks for efficient photocatalytic H2 evolution by Yanchang Huang, Bin Gao, Qihang Huang, De‐Li Ma, Hongwei Wu, Cheng Qian

“…However, their efficiency is hindered by fast charge recombination and low photostability. Herein, we proposed a donor structural engineering strategy for improving the photocatalytic activity of D‒A COFs to tackle these problems. …”
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Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization by Silvia Codenotti, Michela Asperti, Maura Poli, Luisa Lorenzi, Alberto Pietrantoni, Matteo Cassandri, Francesco Marampon, Alessandro Fanzani

“…Fatostatin and lovastatin produced rapid attenuation of Erk1/2 and Akt1 signaling in RMS lines, and oral administration of lovastatin reduced tumor mass growth of xenografted RD cells in NOD/SCID mice. Finally, we found that forced Akt1 activation in RD cells was sufficient to drive SREBP2, HMGCR and SQLE protein expression, promoting increased susceptibility to MVP inhibitors. …”
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Exogenous organic acids promoted phytoremediation by Hydrangea macrophylla in cadmium‑contaminated soil by Yunjing Song, Qian Cheng, Bing Zhao

“…Nevertheless, TF values were all less than 1. We posit that using H. macrophylla and organic acids could reduce the Cd bioavailability in the soil mainly through rhizosphere immobilization and plant absorption. …”
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Physical education curriculum systematizing based on action research: a collaborative network between teacher-researchers from public schools in Quixadá — Ceará, Brazil by Rener Victor Oliveira de Souza, Maurício Teodoro de Souza, Luciano Nascimento Corsino, Willian Lazaretti da Conceição, Carla Ulasowicz, Luciana Venâncio, Luciana Venâncio, Luiz Sanches Neto, Luiz Sanches Neto

“…Data has been analyzed through thematic analysis, characterizing a collaborative network between participants. We identified that curricular documents direct subject content towards the predominance of cultural elements. …”
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Continuous Glucose Monitoring in Newly Diagnosed Type 2 Diabetes Patients Reveals a Potential Risk of Hypoglycemia in Older Men by Feng-fei Li, Bing-li Liu, Hong-hong Zhu, Ting Li, Wen-li Zhang, Xiao-fei Su, Jin-dan Wu, Xue-qin Wang, Ning Xu, Wei-Nan Yu, Qun Yuan, Guan-cheng Qi, Lei Ye, Kok-Onn Lee, Jian-hua Ma

“…Objectives. We performed continuous glucose monitoring (CGM) to define the features of patients with newly diagnosed type 2 diabetes (T2D) before and after Continuous Subcutaneous Insulin Infusion (CSII) therapy. …”
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Practice and application of learning curve theory in improving prescription review skills in standardized training for pharmacists in medical institutions by Jingjing Xu, Qin He, Min Xu, Kun Fu, Jiao Luo, Ying Ma, Xu Liu, Hen Xi

“…By applying the learning curve theory, we can scientifically define the developmental stages of pharmacists’ auditing abilities. …”
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Constructing the constitutively active ribosomal protein S6 kinase 2 from <i>Arabidopsis thaliana</i> (AtRPS6K2) and testing its activity <i>in vitro</i> by A. V. Zhigailov, G. E. Stanbekova, D. K. Beisenov, A. S. Nizkorodova, N. S. Polimbetova, B. K. Iskakov

“…In Arabidopsis thaliana, AtRPS6 is phosphorylated by kinase AtRPS6K2, which should in turn be phosphorylated by upper level kinases (AtPDK1 – at serine (S) 296, AtTOR – at threonine (T) 455 and S437) for full activation. We have cloned AtRPS6K2 cDNA gene and carried out in vitro mutagenesis replacing codons encoding S296, S437 and T455 by triplets of phosphomimetic glutamic acid (E). …”
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Exploring barriers to early breast examination and screening among Arab women in the MENA region: A KAP study by Ehsan Qtaishat, Reem Al-Ajlouni, Khawlah Ammar, Mohammed Liswi, Abdallah Al-Ani, Rasha Fakheraldeen, Shorouq Al-hasson

“…Conclusion: Among our population of sampled adult Arab women, knowledge of breast cancer, its risk factors, and early detection methods are not satisfactory. Thus, we recommend increased awareness efforts and a profound exploration of the effectiveness of such interventions.…”
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Evaluating a novel team learning approach for integrating drugs in sports education in preclinical medical training by Samuel Pelobello, Grayson Potter, Daniel K. Rogstad, Andrew J. Mock, Sean M. Wilson

“…At Loma Linda University School of Medicine, we are seeking to provide medical students with education on the topic of drugs in sports so that they can better serve their patients. …”
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Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic... by Virginija Kalinauskaite-Zukauske, Andrius Januskevicius, Ieva Janulaityte, Skaidrius Miliauskas, Kestutis Malakauskas

“…The aim of this study was to investigate the changes in serum levels of IL-25 and TSLP after a single dose of mepolizumab, a humanized monoclonal antibody to interleukin-5 (IL-5), in patients with severe non-allergic eosinophilic asthma (SNEA). We examined 9 SNEA patients before and four weeks after administration of 100 mg mepolizumab subcutaneously. …”
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Large annotated ultrasound dataset of non-alcoholic fatty liver from Saudi hospitals for analysis and applicationsOpen Science framework or (OSF) by Fahad Alshagathrh, Mahmood Alzubaidi, Khalid Alswat, Ali Aldhebaib, Bushra Alahmadi, Meteb Alkubeyyer, Abdulaziz Alosaimi, Amani Alsadoon, Maram Alkhamash, Jens Schneider, Mowafa Househ

“…Unlike other datasets that rely on bounding boxes, we opted for full-image labelling based on biopsy findings, which link to histopathological results, ensuring more precise representation of liver conditions. …”
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Usefulness of computed tomography-guided puncture biopsy coupled with rapid on-site evaluation for diagnosis of pulmonary lesions: a systematic review and meta‑analysis by Zhongbao Zhang, Rui Liu, JunLin Li, Kai Zhang, Yuan Li, Xiaoqin Zhang, Sanjay Rastogi

“…The rapid on-site evaluation (ROSE) method allows for quick assessment of the features, cytomorphological traits, and appropriateness of the obtained tissue samples, and might further accelerate the diagnostic workup. Aim: We aimed to investigate the diagnostic value of CT-guided aspiration biopsy combined with ROSE for assessment of pulmonary lesions. …”
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Human intestinal nematode infections in Sri Lanka: A scoping review. by Nalini Kaushalya Jayakody, Anjana Silva, Susiji Wickramasinghe, Nilanthi de Silva, Sisira Siribaddana, Kosala Gayan Weerakoon

“…This review aims to explore Sri Lanka's HINI distribution, trends, diagnostics, control and challenges.<h4>Methodology</h4>We reviewed published information on HINIs in Sri Lanka in electronic databases, local journals and grey literature from inception to September 2022. …”
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Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats by Ga-Young Choi, Hyun-Bum Kim, Eun-Sang Hwang, Seok Lee, Min-Ji Kim, Ji-Young Choi, Sung-Ok Lee, Sang-Seong Kim, Ji-Ho Park

“…It has been known for the anti-inflammatory, antistress, and neurotropic effects. Here we examined curcumin effect in neural plasticity and cell viability. 60-channel multielectrode array was applied on organotypic hippocampal slice cultures (OHSCs) to monitor the effect of 10 μM curcumin in long-term depression (LTD) through low-frequency stimulation (LFS) to the Schaffer collaterals and commissural pathways. …”
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Youth experiencing homelessness at risk for suicide: psychosocial risk factors and service use patterns by Laura J. Chavez, Kelly J. Kelleher, Alicia Bunger, Xin Feng, Margaret Fitzpatrick, Jodi L. Ford, Allen B. Mallory, Arielle H. Sheftall, Tansel Yilmazer, Alexis Pizzulo, Jesse L. Hawke, Mattina A. Davenport, Natasha Slesnick

“…Methods A cross-sectional analysis of youth enrolled in a supportive housing randomized clinical trial. We categorized suicide risk into three groups (low-, moderate-, and high-risk) based on suicidal ideation and past-year suicide attempt. …”
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Predictors, patterns, and correlates of moderate-severe psychological distress among New York City College Students during Waves 2–4 of COVID-19 by Craig J. Heck, Deborah A. Theodore, April Autry, Brit Sovic, Cynthia Yang, Sarah Ann Anderson-Burnett, Caroline Ray, Eloise Austin, Joshua Rotbert, Jason Zucker, Marina Catallozzi, Magdalena E. Sobieszczyk, Delivette Castor

“…Abstract The COVID-19 pandemic may have exacerbated mental health conditions by introducing and/or modifying stressors, particularly in university populations. We examined longitudinal patterns, time-varying predictors, and contemporaneous correlates of moderate-severe psychological distress (MS-PD) among college students. …”
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ANGPTL3 overcomes sorafenib resistance via suppression of SNAI1 and CPT1A in liver cancer by Yang-Hsiang Lin, Cheng-Yi Chen, Hsiang-Cheng Chi, Meng-Han Wu, Ming-Wei Lai, Chau-Ting Yeh

“…Clinical correlation analysis revealed that ANGPTL3 was negatively associated with SNAI1 expression. In conclusion, we identify a novel association between ANGPTL3, SNAI1 and CPT1A on sorafenib therapeutic response. …”
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Wildfire danger under changing climates in the southern Great Plains throughout the 21st century by Shanmin Fang, Jia Yang, Chris B. Zou, Erik S. Krueger, Tyson E. Ochsner, Quan Zhang

“…Therefore, our objectives were to (1) simulate the spatial and temporal dynamics of the Burning Index (BI), a widely used fire danger index in the National Fire Danger Rating System (NFDRS), and high fire danger days based on CMIP5 climate simulations, comparing the 1986–2005 historical period and 2006–2099 under two climate change scenarios (RCP4.5 and RCP8.5), and (2) identify important weather variables driving projected BI changes. We found that the BI would increase at 0.1 × 10 ft per decade under RCP4.5 and 0.4 × 10 ft per decade under RCP8.5. …”
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