Genome-Wide Identification and Expression Analysis of PkNRT Gene Family in Korean Pine (<i>Pinus koraiensis</i>) by Xinyu Zhao, Haibo Wu, Boyang Li, Pengyang Wang, Peng Zhang, Hailong Shen, Jianfei Yang

“…Therefore, exploration of the role of NRTs in response to various NO₃⁻ conditions is crucial for improving N utilization efficiency (NUE). Here, we present a comprehensive genome-wide analysis and characterization of the NRT gene family in Korean pine, an invaluable tree species cultivated extensively in northeastern China. …”
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16-Channel Hybrid WDM-PDM-MDM (de) Multiplexer for Multi-Band Large-Capacity Optical Transmission System Based on Thick Si<inline-formula><tex-math notation="LaTeX">$_{3}$</tex-mat... by Deyue Ma, Xiwen He, Chen Zhou, Mingyue Xiao, Jiqiao Liu, Weibiao Chen, Zhiping Zhou

“…We propose a novel design of hybrid multi-band wavelength/polarization/mode (de)multiplexer based on 800 nm thick Si<inline-formula><tex-math notation="LaTeX">$_{3}$</tex-math></inline-formula>N<inline-formula><tex-math notation="LaTeX">$_{4}$</tex-math></inline-formula> platform. …”
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Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro by Paulina Kobylka, Pawel Bakun, Joanna Kuzminska, Tomasz Goslinski, Marek Murias, Malgorzata Kucinska

“…Compound <b>2a-B</b> led to phosphatidylserine translocation, increased caspase 3/7 activity, and decreased mitochondrial membrane potential, suggesting a mitochondrial apoptosis pathway. We found that the Akt signaling pathway may modulate the activity of compound <b>2a-B</b>, as evidenced by enhanced cytotoxic activity in combination with MK-2206, an Akt 1/2/3 inhibitor. …”
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Evidence for Activation of Toll-Like Receptor and Receptor for Advanced Glycation End Products in Preterm Birth by Taketoshi Noguchi, Toshiyuki Sado, Katsuhiko Naruse, Hiroshi Shigetomi, Akira Onogi, Shoji Haruta, Ryuji Kawaguchi, Akira Nagai, Yasuhito Tanase, Shozo Yoshida, Takashi Kitanaka, Hidekazu Oi, Hiroshi Kobayashi

“…Toll-like receptors (TLRs) and receptor for advanced glycation end products (RAGE) and their ligands were all found to play a key role in inflammation. In the present study, we reviewed TLR and RAGE expression, their ligands, and signaling in preterm birth. …”
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Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults by Timothy D. Verstynen, Brighid Lynch, Destiny L. Miller, Michelle W. Voss, Ruchika Shaurya Prakash, Laura Chaddock, Chandramallika Basak, Amanda Szabo, Erin A. Olson, Thomas R. Wojcicki, Jason Fanning, Neha P. Gothe, Edward McAuley, Arthur F. Kramer, Kirk I. Erickson

“…In neocortical areas, higher cardiorespiratory fitness levels are associated with increased gray matter volume, and these volumetric differences mediate enhanced cognitive performance in a variety of tasks. Here we examine whether cardiorespiratory fitness correlates with the volume of the subcortical nuclei that make up the basal ganglia and whether this relationship predicts cognitive flexibility in older adults. …”
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Prognostic role of con-/discordant coronary flow reserve and microvascular resistance in coronary microvascular disease: a systematic review and network meta-analysis by Ibtihal Al Amri, Federico Oliveri, Jin Al-Gully, Jessica Parisa Forouzanfar, Jose Manuel Montero-Cabezas, Johan Wouter Jukema, Melina Cynthia den Haan, Brian Oscar Bingen

“…Patients were divided into four groups: (1) normal CFR and MR, (2) abnormal CFR and MR, (3) abnormal CFR with normal MR and (4) normal CFR with abnormal MR and analysed for all-cause mortality and major adverse cardiovascular events (MACE).Results We identified four studies representing 2310 total participants. …”
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Rosiglitazone Restores Endothelial Dysfunction in a Rat Model of Metabolic Syndrome through PPARγ- and PPARδ-Dependent Phosphorylation of Akt and eNOS by Zhigang Zhao, Zhidan Luo, Peijian Wang, Jing Sun, Hao Yu, Tingbing Cao, Yinxing Ni, Jing Chen, Zhencheng Yan, Daoyan Liu, Zhiming Zhu

“…Recently, studies suggested that single dose of rosiglitazone also has direct vascular effects, but the mechanisms remain uncertain. Here we established a diet-induced rat model of MS. The impaired vasorelaxation in MS rats was improved by incubating arteries with rosiglitazone for one hour. …”
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Analysis of Atrial Fibrillation Treatment Regimes in a Multicenter Cohort of Transcatheter Edge-to-Edge Mitral Valve Repair Patients by Christian Waechter, Felix Ausbuettel, Georgios Chatzis, Dieter Fischer, Holger Nef, Sebastian Barth, Philipp Halbfaß, Thomas Deneke, Sebastian Kerber, Dimitar Divchev, Bernhard Schieffer, Ulrich Luesebrink

“…Fundamental data on AF characteristics and treatment regimes in this special cohort of patients are lacking. Methods. We retrospectively analyzed the data of 542 consecutive patients with severe MR undergoing TMVR in three tertiary heart centers with special focus on AF type and underlying treatment strategies. …”
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Efficacy of Adjunctive Antiseptic Lavage Solution in Managing Acute Hip/Knee Prosthetic Joint Infection: A Comparative Study in a Tertiary Revision Center by Jonathan Quinn, FRACS, Bernard H. van Duren, DPhil, FRCS, Reshid Berber, PhD, FRCS, Mark Higgins, FRCS, Hosam E. Matar, FRCS, Andrew R. Manktelow, FRCS, Benjamin V. Bloch, FRCS

“…Background: Debridement, antibiotics and implant retention (DAIR) procedure is well-established as a management option for acute periprosthetic joint infection (PJI). We investigated the infection eradication rates of DAIR procedures at our center using Bactisure wound lavage. …”
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Migration of Health Workers and Its Impacts on the Nigerian Health Care Sector: Protocol for a Scoping Review by David Omiyi, Ebenezer Arubuola, Marcus Chilaka, Md Shafiqur Rahman Jabin

“…ResultsThe process of selecting studies will be shown using a PRISMA ScR flowchart, and information gathering will be done through a charting table that has been prepared in advance. We plan to collect data from January 2025 to March 2025 and present the results to examine publication patterns and study details. …”
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Effects of using different levels of dietary chitosan on some immune indices and antioxidant defense system in Vannamei shrimp, Litopenaeus vannamei by Saeed Dayani, Valiallah Jafari, Roghayeh Safari, Seyed Hossein Hoseinifar

“…Materials and Methods: For this purpose, 180 pieces of Vannamei shrimp with an average weight of about 4 g were prepared and kept for 2 weeks to adapt to the test conditions. We prepared 4 groups, each with three repetitions, including the basal diet of zero (control), 1 g (treatment 1 = T1), 2 g (T2) and 4 g (T3) chitosan per kilogram of feed in a completely randomized design for 8 weeks. …”
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Hierarchical Recognition for Urban Villages Fusing Multiview Feature Information by Zhenkang Wang, Nan Xia, Song Hua, Jiale Liang, Xiankai Ji, Ziyu Wang, Jiechen Wang

“…Compared with results from single-view of RSI, the complementarity with SVI for multiview features increased the OA and Kappa by 3.34&#x0025; and 0.079, which could effectively distinguish the old industrial parks. We believe that our proposed hierarchical framework is essential to the scientific and accurate UV recognition, which can guide the urban management and high-quality development.…”
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A preoperative predictive model based on multi-modal features to predict pathological complete response after neoadjuvant chemoimmunotherapy in esophageal cancer patients by Yana Qi, Yanran Hu, Chengting Lin, Ge Song, Liting Shi, Hui Zhu

“…Additionally, both the calibration plot and DCA curves support the clinical utility of the integrated multi-modality model.ConclusionsThe combined multi-modality model we propose can better predict the pCR status of esophageal cancer and help inform clinical treatment decisions.…”
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The Exposure Assessment in Current Time Study: Implementation, Feasibility, and Acceptability of Real-Time Data Collection in a Community Cohort of Illicit Drug Users by Gregory D. Kirk, Beth S. Linas, Ryan P. Westergaard, Damani Piggott, Robert C. Bollinger, Larry W. Chang, Andrew Genz

“…Objective. We describe the study design and evaluate the implementation, feasibility, and acceptability of an ecological momentary assessment (EMA) study of illicit drug users. …”
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Ornithine enantiomers modulate essential oil yield and constituents and gene expression of monoterpenes synthase in Salvia officinalis under well-watered and drought stress conditi... by Maryam Mohammadi-Cheraghabadi, Faezeh Ghanati, Naser Karimi, Mansour Ghorbanpour, Saeid Hazrati

“…The exogenous application of polyamines as osmotically active materials plays a crucial role in enhancing plant tolerance to environmental stress. In this study, we examined the effects of L- and D-enantiomers of ornithine (0 and 1 mM) under both well-watered and drought stress conditions on the growth traits, essential oil (EO) yield, and composition, gene expression, and total phenolic and flavonoid content of Salvia officinalis. …”
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The Treatment Effect of Plantago Major on Lung Cancer Based on the Computed Tomography and Pathological Findings: A Case Report Study by Saade Abdalkareem Jasim, Bashar Mudhaffar Abdullah, Patricio Yánez-Moretta, Wesam R. Kadhum, Yasser Fakri Mustafa, Enas R. Alwaily, Munther Abosoda, Ali Alsalamy, Sada Ghalib Al-Musawi, Alaa A. Omran

“…Previous studies demonstrated the treatment effect of this plant on lung cancer cell lines. Here, we introduced a patient having lung cancer proved by Computed Tomography (CT) and pathological findings. …”
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The diagnostic value of cytology in the mammary intraductal lesions of patients with pathological nipple discharge by Yifei Zeng, Jifeng Li, Dongxiao Zhang, Na Fu, Yu Zhou, Yubo Guo, Min Liu, Hongkai Zhang, Jianchun Cui

“…With postoperative pathological diagnosis as the gold standard, we compared the clinical diagnostic efficacy of the two cytology techniques applied independently and combined with FDS to evaluate their diagnostic value in intraductal lesions. …”
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Respiratory Impairment after Early Red Cell Transfusion in Pediatric Patients with ALI/ARDS by Surender Rajasekaran, Dominic Sanfilippo, Allen Shoemaker, Scott Curtis, Sandra Zuiderveen, Akunne Ndika, Michael Stoiko, Nabil Hassan

“…In the first 48 hours of ventilating patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), a multipronged approach including packed red blood cell (PRBC) transfusion is undertaken to maintain oxygen delivery. Hypothesis. We hypothesized children with ALI/ARDS transfused within 48 hours of initiating mechanical ventilation would have worse outcome. …”
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Zearalenone exacerbates lipid metabolism disorders by promoting liver lipid droplet formation and disrupting gut microbiota by Xiao Han, Bingxin Huangfu, Tongxiao Xu, Kunlun Huang, Xiaoyun He

“…ZEA has the ability to bind to estrogen receptors of humans and animals and is an environmental endocrine disruptor that may interfere with glucose homeostasis and lipid metabolism. In this study, we first investigated the effects of chronic exposure to low doses of ZEA with a high-fat-diet (HFD) in obese C57BL/6 J mice. …”
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IgG4 as a Biomarker in Graves’ Orbitopathy by Michał Olejarz, Ewelina Szczepanek-Parulska, Daniela Dadej, Nadia Sawicka-Gutaj, Remigiusz Domin, Marek Ruchała

“…Typical signs of GO accompanied by increased concentration of IgG4 include younger age at diagnosis, and more severe course of the disease with a higher Clinical Activity Score (CAS).. We strongly recommend considering the diagnosis of GO with elevated IgG4 in patients with an established diagnosis of GD, elevated serum IgG4 levels, and clinical features of ophthalmic disease overlapping with those of IgG4-related orbital disease.…”
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