Kinetics, thermodynamics, and catalysis of the cation incorporation into GeO2, SnO2, and (SnxGe1−x)O2 during suboxide molecular beam epitaxy by Wenshan Chen, Kingsley Egbo, Joe Kler, Andreas Falkenstein, Jonas Lähnemann, Oliver Bierwagen

“…To understand and mitigate this challenge, the present study comprehensively investigates the kinetics and thermodynamics of suboxide incorporation into GeO2, SnO2, and (SnxGe1−x)O2 during suboxide MBE (S-MBE), the latest development in oxide MBE using suboxide sources. We find S-MBE to simplify the growth kinetics, offering better control over growth rates than conventional MBE but without supporting cation-driven oxide layer etching. …”
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Situating the salience and parietal memory networks in the context of multiple parallel distributed networks using precision functional mapping by Young Hye Kwon, Joseph J. Salvo, Nathan L. Anderson, Donnisa Edmonds, Ania M. Holubecki, Maya Lakshman, Kwangsun Yoo, B.T. Thomas Yeo, Kendrick Kay, Caterina Gratton, Rodrigo M. Braga

“…Using high-resolution neuroimaging, we show that individualized estimates of the PMN extend beyond the posterior set and encompass frontal and insula regions canonically ascribed to the SAL. …”
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Micro-Electro Nanofibrous Dressings Based on PVDF-AgNPs as Wound Healing Materials to Promote Healing in Active Areas by Liu T, Xie F, Geng L, He R, Sun M, Ni T, Xu P, Xing C, Peng Y, Chen K, Fang Y

“…By designing a micro-electro-Nanofiber dressing composed of piezoelectric polyvinylidene fluoride (PVDF) integrated with antimicrobial silver nanoparticles (AgNPs), this research aims to address the dual challenges of promoting effective wound healing and maintaining joint mobility.Methods: Herein, we developed a novel micro-electro-Nanofiber dressing using electrospinning technology, incorporating polyvinylidene fluoride (PVDF) with silver nanoparticles (AgNPs). …”
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The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues by Xin Xu, Hirokazu Fukui, Ying Ran, Xuan Wang, Yoshihito Inoue, Nobuhiko Ebisudani, Heihachiro Nishimura, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Hiroshi Kiyama, Hiroto Miwa

“…However, the pathophysiological significance of Reg family protein overexpression and its regulation is still unclear. In the present study, we investigated the profile of Reg family gene expression in a colitis model and focused on the regulation of Reg IIIβ and IIIγ, which are overexpressed in inflamed colonic mucosa. …”
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Transcriptomic analysis of Rhipicephalus microplus hemocytes from female ticks infected with Babesia bovis or Babesia bigemina by Rubikah Vimonish, Janaina Capelli-Peixoto, Wendell Johnson, Lowell Kappmeyer, Perot Saelao, Naomi Taus, Chungwon Chung, Massaro Ueti

“…Still, it is unknown how tick hemocytes respond to B. bovis or B. bigemina infection. In this study, we conducted a transcriptomic analysis of hemocytes from female Rhipicephalus microplus ticks infected with Babesia parasites to understand how gene expression changes during parasite infection. …”
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Store Separation: Photogrammetric Solution for the Static Ejection Test by Luiz Eduardo Guarino de Vasconcelos, Nelson Paiva Oliveira Leite, André Yoshimi Kusumoto, Leandro Roberto, Cristina Moniz Araujo Lopes

“…The experiments were carried out at IPEV (Flight Test Research Institute)/Brazil, and the results were considered satisfactory. We advocate that the knowledge gained through this research contributes to the development of new methods that permit almost real-time analysis in store separation tests.…”
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Laboratory Comparison of Rapid Antigen Diagnostic Tests for Lymphatic Filariasis: STANDARD Q Filariasis Antigen Test (QFAT) Versus Bioline Filariasis Test Strip (FTS) by Patricia M. Graves, Jessica L. Scott, Alvaro Berg Soto, Antin Y. N. Widi, Maxine Whittaker, Colleen L. Lau, Kimberly Y. Won

“…Accurate rapid diagnostic tests (RDTs) are needed to diagnose lymphatic filariasis (LF) in global elimination programmes. We evaluated the performance of the new STANDARD Q Filariasis Antigen Test (QFAT) against the Bioline Filariasis Test Strip (FTS) for detecting <i>W. bancrofti</i> antigen (Ag) in laboratory conditions, using serum (n = 195) and plasma (n = 189) from LF-endemic areas (Samoa, American Samoa and Myanmar) and Australian negative controls (n = 46). …”
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Imatinib Mesylate Effectiveness in Chronic Myeloid Leukemia with Additional Cytogenetic Abnormalities at Diagnosis among Black Africans by Tolo Diebkilé Aïssata, Duni Sawadogo, Clotaire Nanho, Boidy Kouakou, N'dogomo Meité, N'Dhatz Emeuraude, Ayémou Roméo, Sekongo Yassongui Mamadou, Paul Kouéhion, Konan Mozart, Gustave Koffi, Ibrahima Sanogo

“…But what about the results of this treatment in CML associated with additional cytogenetic abnormalities at diagnosis among black Africans? For this, we retrospectively studied 27 cases of CML associated with additional cytogenetic abnormalities, diagnosed in the department of clinical hematology of the University Hospital of Yopougon in Côte d'Ivoire, from May 2005 to October 2011. …”
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Physically engineered extracellular vesicles targeted delivering miR-21-5p to promote renoprotection after renal ischemia-reperfusion injury by Di Wu, Wenjie Ma, Liucheng Wang, Chengcheng Long, Silin Chen, Jingyu Liu, Yiguan Qian, Jun Zhao, Changcheng Zhou, Ruipeng Jia

“…Endothelial progenitor cells (EPCs) derived extracellular vesicles (EVs) hold promise as cell-free therapies for treating renal IRI; however, their efficacy is limited by low delivery efficiency. In this study, we developed neutrophils (NEs) membrane-modified EVs (N-EVs) by exploiting the natural properties of NEs to target damaged endothelium. …”
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Thyroid Hormone-Induced Cytosol-to-Nuclear Translocation of Rat Liver Nrf2 Is Dependent on Kupffer Cell Functioning by Luis A. Videla, Pamela Cornejo, Pamela Romanque, Catherine Santibáñez, Iván Castillo, Romina Vargas

“…L-3,3′,5-triiodothyronine (T3) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redox-sensitive transcription factor mediating cytoprotection. In this work, we studied the role of Kupffer cell respiratory burst activity, a process related to reactive oxygen species generation and liver homeostasis, in Nrf2 activation using the macrophage inactivator gadolinium chloride (GdCl3; 10 mg/kg i.v. 72 h before T3 [0.1 mg/kg i.p.]) or NADPH oxidase inhibitor apocynin (1.5 mmol/L added to the drinking water for 7 days before T3), and determinations were performed 2 h after T3. …”
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A prediction nomogram for residual after negative pressure aspiration for endogenic cesarean scar ectopic pregnancy: a retrospective study by Yan Lei, Na Zhang, Yu Liu, Xin Du

“…Abstract Background We aimed to establish a predictive nomogram to evaluate the incidence of residual tissue in patients with endogenic cesarean scar ectopic pregnancy after negative pressure aspiration. …”
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Uric acid to albumin ratio is a novel predictive marker for all-cause and cardiovascular death in diabetic patients: a prospective cohort study by Shengnan Chen, Shengnan Chen, Ming Zhang, Shouye Hu, Xiaolong Shao, Lin Liu, Zhi Yang, Kai Nan

“…Diabetes-related premature mortality is largely preventable and reversible if identified and managed early. Accordingly, we intend to investigate the predictive value of uric acid to albumin ratio (UAR) for all-cause and cardiovascular death in diabetic patients.MethodsUnivariate and multivariate Cox regression analyses were performed to identify risk factors for all-cause death of diabetic patients. …”
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C5a-C5aR1 axis mediates lung inflammation and fibrosis induced by single-walled carbon nanotubes via promoting neutrophils recruitment by Jiaojiao Zhu, Xiang Zhang, Lanlan Li, Hongxu Yang, Hang Liu, Danyang Wu, Zikai Liu, Bin Liu, Tong Shen

“…However, the molecular mechanisms of single-walled CNT (SWCNT)-provoked lung injury remain to be elucidated. Here, we established a mice model of SWCNT-induced lung injury by intratracheal instillation and found that C5a-C5a receptor-1 (C5aR1) signaling was significantly activated along with abundant neutrophils recruitment in lungs at early phase post SWCNT administration, which were positively correlated with early lung inflammation and late pulmonary fibrosis. …”
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Determining the mechanism of Shuxuening injection against liver cirrhosis through network pharmacology and animal experiments by Qiyao Liu, Tingyu Zhang, Yongan Ye, Xin Sun, Huan Xia, Xu Cao, Xiaoke Li, Wenying Qi, Yue Chen, Xiaobin Zao

“…Serum and liver tissues of the mice were collected for the detection of indicators, pathological staining, and expression analysis of hub targets using quantitative real-time polymerase chain reaction (qRT-PCR). Results: We identified 368 overlapping genes (OLGs) between SXN and LC targets. …”
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Resourceful and economical designing of fermentation medium for lab and commercial strains of yeast from alternative feedstock: ‘transgenic oilcane’ by Shraddha Maitra, Bruce Dien, Kristen Eilts, Nurzhan Kuanyshev, Yoel R. Cortes-Pena, Yong-Su Jin, Jeremy S. Guest, Vijay Singh

“…To this end, hydrolysates generated from engineered sugarcane—‘oilcane’ bagasse contain added phenolics and fatty acids that further restrict the growth of fermenting microorganisms and necessitate nutrient supplementation and/or detoxification of hydrolysate which makes the fermentation process expensive. Herein, we propose a resourceful and economical approach for growing lab and commercial strains of S. cerevisiae on unrefined cellulosic sugars aerobically and fermentatively. …”
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Mitigating biomass recalcitrance for plant‐based bioenergy production by Vincent Ninkuu, Zhixin Liu, Yaping Zhou, Enzhi Guo, Xiao Song, Peibo Gao, Yajia Xie, Xuwu Sun

“…Several attempts have been made towards reducing the biomass recalcitrance of straw using genetic transformations. We present a review highlighting potential plant candidates for bioenergy production, the lignocellulose composition of the feedstock, how the composition can impede enzymatic degradation, the regulation of lignocellulose polymer biosynthesis, and the influence of genetic transformation on biomass saccharification. …”
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Systematic review and meta-analysis of the impact of abnormal expression of long non coding RNA on the prognosis of acute myeloid leukemia by Guihong Liu, Liangliang Sun, Peng Lv, Rong Qiao, Lihang Wang, Arong Jin

“…This study aims to evaluate the association between aberrant lncRNA expression and poor prognosis in AML patients, and to systematically assess the relationship between aberrant lncRNA expression and AML prognosis.MethodsWe conducted a comprehensive literature search in PubMed, Embase, Cochrane Library, CNKI (China National Knowledge Infrastructure), WanFang (China Wanfang Database), VIP (China VIP Database), and Sinomed (China Biomedical Literature Database) to identify relevant Chinese and English articles. …”
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Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity by Linzi Li, Xueying Lei, Lin Chen, Ya Ma, Jun Luo, Xuebo Liu, Xinglian Xu, Guanghong Zhou, Xianchao Feng

“…However, whether quercetin compounds can attenuate AA-induced liver injury and the specific mechanism are not clear. Here, we studied the mechanism and structure-activity relationship of quercetin compounds in reducing AA-induced hepatotoxicity in vivo and in vitro. …”
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Affordability of Essential Medicines and Associated Factors in Public Health Facilities of Jimma Zone, Southwest Ethiopia by Eyassu Mathewos Oridanigo, Waju Beyene Salgedo, Feyera Gebissa Kebene

“…The average cost of dispensed medicines in the surveyed health facilities was not affordable for most of the patients. We recommend both social- and community-based health insurance schemes should be expanded to the study area.…”
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Comparative analysis of gene expression in tea plant (Camellia sinensis (L.) Kuntze) under low-temperature stress by L. S. Samarina, A. O. Matskiv, N. G. Koninskaya, T. A. Simonyan, V. I. Malyarovskaya, L. S. Malyukova

“…Efficient breeding to develop frost-tolerant cultivars requires a reliable set of genetic markers for identifying resistance donors, and that is why it is necessary to reveal the specific genetic response in frost-tolerant genotypes in comparison with frost- susceptible ones. In this work, we performed a comparative analysis of the expression of 18 tea genes (ICE1, CBF1, DHN1, DHN2, DHN3, NAC17, NAC26, NAC30, bHLH7, bHLH43, P5CS, WRKY2, LOX1, LOX6, LOX7, SnRK1.1, SnRK1.2, SnRK1.3) under cold and frost conditions in two tea genotypes, tolerant and susceptible. …”
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