Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing by Xiaofei Wang, Xiaowen Cheng, Huiling Liu, Xiaohuan Mu, Hao Zheng

“…The ever-increasing role of scRNA-seq in dietary food research with further improvement can provide sub-cellular information and the coupling between other cellular modalities. In this review, we propose utilizing scRNA-seq to more effectively capture the subtle and complex effects of food chemicals, and how they may lead to health problems at single-cell resolution. …”
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Highly Stable Antitumor Silver-Lipid Nanoparticles Optimized for Targeted Therapy by Darwish A, Sándor N, Szenti I, Marosvölgyi T, Juhász K, Rónavári A, Kachal E, Kutus B, Kónya Z, Balogi Z

“…To enhance bioavailability, minimize adverse effects and enable targeted drug delivery AgNPs may be encapsulated in liposomes. In this study we aimed to create highly stable and effective antitumor AgNP lipid formulations (LAgs).Methods: Uncapped and citrate-stabilized AgNPs were encapsulated by the lipid film hydration method using several phospholipid mixtures, followed by the essential removal of unencapsulated AgNPs by size exclusion chromatography (SEC). …”
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An Attenuated Cytomegalovirus Vaccine with a Deletion of a Viral Chemokine Gene Is Protective against Congenital CMV Transmission in a Guinea Pig Model by Michael P. Leviton, Juan C. Lacayo, K. Yeon Choi, Nelmary Hernandez-Alvarado, Andrew Wey, Mark R. Schleiss

“…Congenital GPCMV infection was also reduced, from 35/50 (70%) in controls to 9/52 (17%) in the vaccine group (P<0.0001). We conclude that deletion of an immune modulation gene can attenuate the pathogenicity of GPCMV while resulting in a viral vaccine that retains immunogenicity and demonstrates efficacy against congenital infection and disease.…”
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CircCCT2/miR-146a-5p/IRAK1 axis promotes the development of head and neck squamous cell carcinoma by Long He, Lanruo Li, Liting Zhao, Xiaoya Guan, Yujia Guo, Qi Han, Huina Guo, Hongliang Liu, Chunming Zhang

“…High circCCT2 levels were associated with advanced T stage, N stage, clinical stage and poor prognosis. Functionally, we verified that circCCT2 promotes HNSCC development in vitro and in vivo. …”
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The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis by Fei Huang, Yueqiang Li, Ranran Xu, Anying Cheng, Yongman Lv, Qingquan Liu

“…The aim of this study was to explore whether circulating suPAR was associated with antineutrophil cytoplasmic autoantibody- (ANCA-) associated vasculitis (AAV) disease activity. Methods. We evaluated 90 AAV patients with follow-up data and 35 normal controls; their plasma suPAR and C-reactive protein (CRP) levels were measured by ELISA. …”
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Mapping Susceptibility and Risk of Land Subsidence by Integrating InSAR and Hybrid Machine Learning Models: A Case Study in Xi&#x0027;an, China by Chen Chen, Mimi Peng, Mahdi Motagh, Xinxin Guo, Mengdao Xing, Yinghui Quan

“…It requires not only focusing on the extent or rate of deformation but also evaluating the susceptibility and risk of subsidence. In this article, we propose a new comprehensive subsidence susceptibility and risk assessment strategy by integrating InSAR observation and hybrid machine learning models, which is first and successfully employed over Xi&#x0027;an area. …”
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Clinical efficacy and safety of proton radiotherapy for ocular conjunctival malignancies: a systematic review and meta-analysis by Tingwei Zheng, Tingwei Zheng, Dandan Wang, Yuxin Miao, Yuxin Miao, Meng Dong, Qin Liu, Qin Liu, Qiuning Zhang, Huiling Bai, Huiling Bai, Hongtao Luo, Meixuan Li

“…This study conducts a systematic review and meta-analysis to assess the effectiveness and safety of PBT in treating malignant conjunctival tumors.MethodsWe searched for studies on PBT for ocular conjunctival malignancies in PubMed, Embase, Cochrane Library, and Web of Science (WoS) databases up to November 25, 2023. …”
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MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays by Alan F. Rubin, Jeremy Stone, Aisha Haley Bianchi, Benjamin J. Capodanno, Estelle Y. Da, Mafalda Dias, Daniel Esposito, Jonathan Frazer, Yunfan Fu, Sally B. Grindstaff, Matthew R. Harrington, Iris Li, Abbye E. McEwen, Joseph K. Min, Nick Moore, Olivia G. Moscatelli, Jesslyn Ong, Polina V. Polunina, Joshua E. Rollins, Nathan J. Rollins, Ashley E. Snyder, Amy Tam, Matthew J. Wakefield, Shenyi Sunny Ye, Lea M. Starita, Vanessa L. Bryant, Debora S. Marks, Douglas M. Fowler

“…Abstract Multiplexed assays of variant effect (MAVEs) are a critical tool for researchers and clinicians to understand genetic variants. Here we describe the 2024 update to MaveDB ( https://www.mavedb.org/ ) with four key improvements to the MAVE community’s database of record: more available data including over 7 million variant effect measurements, an improved data model supporting assays such as saturation genome editing, new built-in exploration and visualization tools, and powerful APIs for data federation and streamlined submission and access. …”
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Dataset of speech produced with delayed auditory feedbackOpen Science FrameworkOpen Science Framework by Matthias Heyne, Monique C. Tardif, Alexander Ocampo, Ashley P. Petitjean, Emily J. Hacker, Caroline N. Fox, Megan A. Liu, Madeline Fontana, Vincent Pennetti, Jason W. Bohland

“…To our knowledge, there are currently no publicly available research datasets containing recordings of speech produced with DAF. Here we describe a large dataset of speech produced with DAF using modern experimental methods with systematic controls and varied speaking materials, including phonotactically legal, nonword syllable sequences and American English sentences. …”
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Saliva-acquired pellicle inspired multifunctional gargle with wet adhesion, photodynamic antimicrobial, and In situ remineralization properties for dental caries prevention by Jiayi Shi, Xuekai Qi, Ying Ran, Qiang Zhou, Yiqin Ding, Lujian Li, Youyun Zeng, Dongchao Qiu, Zhibin Cai, Xiaojun Cai, Yihuai Pan

“…Inspired by the wet adhesion properties of the salivary acquired pellicle, we developed a multifunctional gargle named Ce6@PDN-SAP (CP-SAP). …”
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Unveiling the inhibitory effect of hydrogen-decorated voids and dislocation loops on the glide of edge dislocation in tungsten by Qing-Yuan Ren, Yu-Hao Li, Yu-Chen Du, Tian-Ren Yang, Dmitry Terentyev, Wei-Zhong Han, Hong-Bo Zhou, Guang-Hong Lu

“…Using molecular dynamics simulations, we investigate the impact of H aggregation within voids and ½ <111> dislocation loops on obstructing the glide of ½ <111> edge dislocations. …”
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Characteristics of Inpatient Hypertension Cases and Factors Associated with Admission Outcomes in Ashanti Region, Ghana: An Analytic Cross-Sectional Study by Kenneth Nuamah, Harriet Affran Bonful, Joseph Danso Yeboah, Ebenezer Antwi Amankwaah, Daniel Boakye, Samuel Kwame Owusu, Adwoa Aduako Owusu, Freddie Amponsah, Fred Adomako-Boateng, Alexis Nang-Beifubah, Margaret Gyapong, Anthony Ofosu, Bertha Garshong, Evelyn K. Ansah

“…It has been featured in the top ten causes of OPD attendance, admissions, and deaths since 2012. We investigated the sociodemographic characteristics and spatial distribution of inpatient hypertensives and factors associated with their admission outcomes. …”
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A Mitochondria‐Related Signature in Diffuse Large B‐Cell Lymphoma: Prognosis, Immune and Therapeutic Features by Zhen‐Zhong Zhou, Jia‐Chen Lu, Song‐Bin Guo, Xiao‐Peng Tian, Hai‐Long Li, Hui Zhou, Wei‐Juan Huang

“…Distinct immune microenvironment, responses to immunotherapy and predictive drug IC50 values were found between groups. Conclusions We established a novel prognostic mitochondria‐related signature by machine learning algorithm, which also demonstrated outstanding predictive value in tumor microenvironment and responses to therapies.…”
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Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction by Iwona Swiatkiewicz, Marek Kozinski, Przemyslaw Magielski, Tomasz Fabiszak, Adam Sukiennik, Eliano Pio Navarese, Grazyna Odrowaz-Sypniewska, Jacek Kubica

“…To assess the value of C-reactive protein (CRP) in predicting postinfarct left ventricular remodelling (LVR). Methods. We measured in-hospital plasma CRP concentrations in patients with a first ST-segment elevation myocardial infarction (STEMI). …”
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Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice by Xiaoyan Duan, Xiaoyan Duan, Xiaoyan Duan, Xiaoyan Duan, Rilige Wu, Jianbo Li, Jianbo Li, Zeya Li, Yanqi Liu, Ping Chen, Bangmao Wang, Bangmao Wang, Bangmao Wang

“…BackgroundInflammatory bowel disease (IBD) has become a global public health problem with complex pathogenesis and limited therapeutic options. We aimed to investigate the potential mechanisms by which Bifidobacterium lactis V9 (V9) alleviated colitis in a dextran sodium sulfate-induced colitis model mice.MethodsMice were induced to develop colitis by drinking DSS solution to induce colitis. …”
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Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial by Reiko Yamanaka-Kohno, Yasuhiro Shirakawa, Aya Yokoi, Naoaki Maeda, Shunsuke Tanabe, Kazuhiro Noma, Kazuyoshi Shimizu, Toshiharu Mituhashi, Yoshihide Nakamura, Souto Nanba, Yurika Uchida, Takayuki Maruyama, Manabu Morita, Daisuke Ekuni

“…Meanwhile, 2 weeks of gum-chewing training (GCT) significantly increased TP in healthy university students. We examined whether perioperative GCT would decrease the proportion of patients exhibiting a decline in TP at 2 weeks postoperatively, and prevent postoperative complications, in thoracic ECPs (TECPs). …”
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A Systematic Review of the UAV Technology Usage in ASEAN by Adel Gohari, B. ANUAR AHMAD, Lawali Rabiu, B. A. RUZAIRI RAHIM, A.S.M. Supa'at, I. M. NASSRIN ELAMIN, M. MOHAMMED GISMALLA, Suhail Ibrahim Al-Dharrab, A. ROZEHA RASHID, Sophan Wahyudi Nawawi, Nazri Nasir, Mohd Adib Bin Sarijari, B. NORHADIJA DARWIN, Ali Hussein Muqaibel

“…The aim of this paper is to systematically review the literature to provide pertinent information on UAVs&#x2019; applications among the association of southeast Asian nations (ASEAN) countries by reviewing 179 documents published from 2012 to the end of 2023. Besides, we also investigated the current state of the relevant policies and regulations among member states. …”
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Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation by Xiaoyu Yu, Weiwei Wu, Jingjun Hao, Yuxin Zhou, Deyang Yu, Wei Ding, Xuejuan Zhang, Gaoli Liu, Jianxun Wang

“…There is increasing evidence to suggest that ginger or its bioactive ingredients may block VSMC dedifferentiation, exerting vasoprotective functions; however, the precise mechanisms have not been fully characterized. Therefore, we investigated the effect of ginger on VSMC phenotypic transition in VG remodeling after transplantation. …”
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Healthy Eating Index-2015 and Dietary Total Antioxidant Capacity as Predictors of Prediabetes: A Case-Control Study by Jamal Rahmani, Karim Parastouei, Maryam Taghdir, Heitor O. Santos, Farinaz Hosseini Balam, Mohsen Saberi Isfeedvajani

“…The overall dietary quality, as well as the dietary total antioxidant capacity (DTAC), deserves central attention in the management of borderline high glucose levels since nonpharmacological strategies are imperative in this regard. Thus, we aimed to investigate the association between prediabetes with dietary quality and DTAC. …”
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Composites Based on Poly(ortho-toluidine) and WS₂ Sheets for Applications in the Supercapacitor Field by Teodora Burlanescu, Ion Smaranda, Andreea Androne, Cristina Stefania Florica, Madalina Cercel, Mirela Paraschiv, Adelina Udrescu, Adam Lőrinczi, Petru Palade, Andrei Galatanu, Catalin Negrila, Elena Matei, Monica Dinescu, Radu Cercel, Mihaela Baibarac

“…During the synthesis of the POT/WS₂ composites by SSI and ICP, an additional exfoliation of the WS₂ NPs was reported. In this work, we demonstrated the following: (a) the ICP method leads to POT/WS₂ composites, which contain repeating units of POT in the leucoemeraldine salt (LS) state, while (b) the ECP method leads to POT/WS₂ composites, which contain repeating units of POT in the emeraldine salt (ES) state. …”
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