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71521
Assessing recovery time of ecosystems in China: insights into flash drought impacts on gross primary productivity
Published 2025-02-01“…Nevertheless, the spatiotemporal patterns in gross primary productivity (GPP) recovery time and the factors influencing it remain largely unknown. In this study, we investigate the recovery time patterns in a terrestrial ecosystem in China based on GPP using a random forest regression model and the SHapley Additive exPlanations (SHAP) method. …”
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71522
Development of an in vitro triculture model of intestine inflammation to assess the immunomodulatory properties of cassava and roselle, two African green leafy vegetables
Published 2025-03-01“…Therefore, to study the anti-inflammatory effects of cassava and roselle leaves, commonly consumed as sauces, we developed an in vitro triculture model of intestine inflammation using intestinal Caco-2 (colorectal adenocarcinoma) and HT29-MTX (goblet cell-like) together with the macrophage-like THP-1 cells. …”
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71523
Association between non-high-density lipoprotein cholesterol and type 2 diabetes: a systematic review and meta-analysis of cohort studies
Published 2025-01-01“…Previous studies assessing the relationship between non-HDL and T2D risk remains inconsistent results. We performed a meta-analysis to systematically evaluate this association. …”
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71524
Determination of Methomyl Residues in Bohe by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS)
Published 2020-01-01“…The initial residue level was much higher in roots (79.52 μg/kg), and it can be decreased to 16.73 (after 15 days) μg/kg and 3.31 (20 days) μg/kg, while the least was detected on the mix leaves and stems (44.54 μg/kg), and it can be decreased to 15.35 (after 20 days). In our case, we suggest that a safety interval in the range of 15–20 days should be allowed after the detection of methomyl in water, and the concentration of methomyl was lower than the acceptable daily intake (ADI) of the China Food and Drug Administration (CFDA) (20 μg/kg).…”
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71525
Twelve-Month Retention in and Impact of Enhance®Fitness on Older Adults in Hawai‘i
Published 2019-01-01“…Linear mixed-effects models were applied to analyze the physical performance measures (chair-stands, arm curls, and the up-and-go test) collected at baseline (month 0) and at 4, 8, and 12 months. We also compared the characteristics of participants who participated in the program for 12 months with those who dropped out in order to gain insights on participant retention. …”
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71526
Impact of COVID-19 restrictions on behavioural and psychological symptoms in home-dwelling people with dementia: a prospective cohort study (PAN.DEM)
Published 2022-01-01“…Mini-Mental Status Examination score 15–26 or Functional Assessment Staging score 3–7 covered dementia severity.Main outcome measures Neuropsychiatric Inventory (NPI-12) total (range 0–144), psychosis (range 0–24), hyperactive behaviour (range 0–60) and mood subsyndrome (range 0–48) scores; Cornell Scale for Depression in Dementia (CSDD) total score (range 0–38).Results We found an overall increase in BPSD by NPI-12 total score comparing prepandemic to pandemic levels (median 16 IQR (4.5–29) to 20 (7–32.5), p=0.03) over a mean of 86 days (SD 19). …”
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71527
Clinical relevance of macromolecular complexes involving integrins, potassium and sodium ion channels and the sodium/proton antiporter in human breast cancer
Published 2025-01-01“…A complex composed by β1 integrin, hERG1 K+ channel, the neonatal form of the Na+ channel NaV 1.5 (nNaV1.5) and the Na+/H+ antiporter NHE1 (NHE1/hERG1/β1/nNaV1.5 complex) has been recently described to be expressed and regulate relevant cancer related behaviors in Breast Cancer (BCa) cells. Methods We analyzed the expression and impact on outcome of the genes encoding the four proteins forming the NHE1/hERG1/β1/nNaV1.5 complex (SLC9A1, KCNH2, ITGB1 and SCN5A) in public datasets. …”
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71528
Correlation between the Serum Platelet-Derived Growth Factor, Angiopoietin-1, and Severity of Coronary Heart Disease
Published 2020-01-01“…Serum PDGF and Ang-1 levels were measured by ELISA. We calculated the Gensini score of each patient with CHD according to the result of CAG. …”
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71529
Efficacy of identifying Treatment-Resistant and non-Treatment-Resistant Schizophrenia using niacin skin flushing response combined with clinical feature
Published 2025-02-01“…A total of 269 patients with schizophrenia (99 TRS and 170 NTRS) were included in this study. We conducted NSFR test on 269 participants. Positive and negative syndrome scale (PANSS), repeatable battery for the assessment of neuropsychological status (RBANS) and insight and treatment attitudes questionnaires (ITAQ) were used to assess the patients’ psychiatric symptoms, cognitive function, and attitude towards illness and treatment, respectively. …”
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71530
Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety
Published 2025-03-01“…During GABAergic synaptic transmission, G protein-coupled GABAB receptors (GBRs) activate K+ channels that prolong the duration of inhibitory postsynaptic potentials (IPSPs). We now show that KCTD16, an auxiliary GBR subunit, anchors hyperpolarization-activated cyclic nucleotide-gated (HCN) channels containing HCN2/HCN3 subunits to GBRs. …”
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71531
Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel
Published 2025-01-01“…To address these issues, we have developed a nanoparticle-hydrogel superstructure comprising phototherapeutic liposomal nanobubbles (NB) and fat extract (FE) encapsulated by F-127 hydrogel. …”
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71532
A mediation analysis of meteorological factors on the association between ambient carbon monoxide and tuberculosis outpatients visits
Published 2025-02-01“…This study aims to investigate the short-term association between low-level CO exposure and PTB outpatient visits in a developing region.MethodsWe conducted a time-series study utilizing a distributed lag non-linear model (DLNM) combined with mediating effect analysis, based on daily CO and PTB cases from 2011 to 2020 in Ningbo, China.ResultsAmong all patients with PTB, a 0.1 mg/m3 increase in CO concentration was associated with an increased risk of PTB outpatient visits in the single-pollutant model, particularly at lag days 2–6. …”
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71533
INTERFAITH MARRIAGE CONTROVERSIES IN SEMARANG: AN ANALYSIS OF QUR'ANIC LEGAL EXEGESIS
Published 2024-12-01“…The study aims to address two key questions on how Indonesian society responds to interfaith marriage and what role does the Qur'an play in the interfaith marriage controversy in Semarang. Through this study, we seek to gain an in-depth understanding of the interaction between religious teachings and social responses, with the broader aim of enhancing insights into the influence of Qur'anic exegesis on interfaith marriage dynamics. …”
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71534
Dye-based fluorescent organic nanoparticles made from polar and polarizable chromophores for bioimaging purposes: a bottom-up approach
Published 2024-04-01“…Yet, they raise concern with respect to toxicity and degradability issues. In that context, we have developed innovative bottom-up approaches towards ultrabright dye-based fluorescent organic nanoparticles (dFONs). …”
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71535
In vitro and in vivo studies on bioactive hydroxyapatite-coated magnesium for glaucoma drainage implant
Published 2025-01-01“…Our previous research found that hydroxyapatite-coated Mg (Mg@HA) shows the best biocompatibility and bioactivity, and exhibits the effect of inhibiting fibrosis after filtration surgery in the rabbit model, which is expected to be a promising material for glaucoma drainage device. In this study, we further demonstrated the anti-fibrosis effect of Mg@HA from the molecular signal level and the efficacy of implantation in the rabbit filtration surgery model. …”
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71536
Paraoxonase and Arylesterase Activities, Lipid Profile, and Oxidative Damage in Experimental Ischemic Colitis Model
Published 2012-01-01“…In the present study, since PON1 is known as an HDL-associated antioxidant enzyme that inhibits the oxidative modification of LDL and oxidative stress plays a role in the pathogenesis of mesenteric ischemia, we investigated the changes in PON1 activity and lipid profile in an experimental ischemic colitis model. …”
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71537
Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters: Application of Infrared Fundus Photography in Assessing the Treatment Efficacy
Published 2019-01-01“…Nd:YAG vitreolysis is supposed to be an option for resolving floaters, but its clinical efficacy is undefined. We aimed to evaluate the efficacy of Nd:YAG vitreolysis in treating floater semiquantifiably by determining changes of floater areas on infrared fundus photography (IR). …”
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71538
Why India is struggling to feed their young children? A qualitative analysis for tribal communities
Published 2022-07-01“…The ultimate goal of the Participatory Approach for Nutrition in Children: Strengthening Health Education Engineering and Environment Linkages project is to identify challenges and opportunities for improvement to subsequently develop socioculturally appropriate, tailored, innovative interventions for the successful implementation of appropriate infant and young child feeding (IYCF) practices locally.Design Qualitative research method, involving five phases: (1) identification of local feeding practices; (2) identification of the local needs and opportunities for children aged 6–24 months; and (3–5) analysis of the gathered qualitative data, intervention design, review and distribution.Setting Nine villages in two community development blocks, that is, Ghatol and Kushalgarh, located in the Banswara district in Rajasthan, India.Participants 68 participants completed semistructured interviews or focus group discussions including: mothers, grandmothers, auxiliary nurse midwife, Anganwadi worker, ASHA Sahyogini, school teachers and local elected representative.Phenomenon of interest IYCF practices and the factors associated with it.Analysis Thematic analysis.Results Our results could be broadly categorised into two domains: (1) the current practices of IYCF and (2) the key drivers and challenges of IYCF. We explicate the complex phenomena and emergent model focusing on: mother’s role and autonomy, knowledge and attitude towards feeding of young children, availability of services and resources that shape these practices set against the context of agriculture and livelihood patterns and its contribution to availability of food as well as on migration cycles thereby affecting the lives of ‘left behind’, and access to basic health, education and infrastructure services.Conclusions This interdisciplinary and participatory study explored determinants impacting feeding practices across political, village and household environments. …”
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71539
Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity
Published 2024-01-01“…We encountered five cases that exhibited false-high Hemoglobin A1c (HbA1c) levels when samples were examined using the enzyme-based NORUDIA N HbA1c kit. …”
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71540
Theoretical Aspects of Professional Competence of Police Officers from the Tactical and Operative Response Unit
Published 2021-07-01“…The new challenges have arisen before the new-organized police unit [3, 6]: to minimize the risks which may appear during public events; to decrease tense in the crowd without demonstrating force; to prevent and to resist street criminality; to be on patrol in the city for the operational support of the patrol police crews in the case of calls with the higher degree of the risk; to react on the situations where there is a real threat of using the weapon or another threat to people’s life; to detain people who are hiding from justice or are wanted and can be dangerous. “We need the units of the civil guard with a new mentality, and absolutely a new approach”, said the assistant of the minister of MIA of Ukraine S. …”
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