Medial Orbitofrontal Cortex Is Associated with Fatigue Sensation by Seiki Tajima, Shigeyuki Yamamoto, Masaaki Tanaka, Yosky Kataoka, Masao Iwase, Etsuji Yoshikawa, Hiroyuki Okada, Hirotaka Onoe, Hideo Tsukada, Hirohiko Kuratsune, Yasuomi Ouchi, Yasuyoshi Watanabe

“…It is necessary to elucidate the neural mechanism of fatigue sensation for managing fatigue properly. We performed H2O  15 positron emission tomography scans to indicate neural activations while subjects were performing 35-min fatigue-inducing task trials twice. …”
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Assessment of vegetation in Murchison falls national park five years after the completion of oil and gas exploration by Hindrah Akisiimire, William Tinzaara, Keneth Tumwebaze, Charles K.Twesigye

“…This study sought to study the vegetation frequency index, relative abundance and diversity in former oil pads five years after the completion of oil and gas exploration in MFNP. We counted all observed plant species following a systematic random sampling technique using a (1mx1m) quadrat for herbs, (5mx5m) quadrat for shrubs, and (10mx10m) quadrat for trees. …”
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Direitos humanos e a formação da identidade no atual paradigma cultural by José Vicente Batista Wociechoski

“…Next, I will present a notion of transculturalism as a route to possible adjustments in the design of social relations to better comply with the reality in which we live. Hence, I propose a more transparent dialogue with human rights to the promotion of a more inclusive approach towards cultural differences.…”
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Pathological Complete Response to a Single Dose of Pembrolizumab‐Based Chemoimmunotherapy for Squamous Cell Carcinoma of the Lung: A Case Report by Yugo Matsumura, Seiya Ichihara, Kaori Nii, Kazumasa Nanjo, Naoki Kadota, Yoshio Okano, Hisanori Machida, Nobuo Hatakeyama, Hiroyuki Hino, Keishi Naruse, Tsutomu Shinohara, Shoji Sakiyama, Eiji Takeuchi

“…ABSTRACT We herein describe a patient with non‐small‐cell lung cancer who achieved pCR with a single dose of pembrolizumab‐based chemoimmunotherapy followed by surgery. …”
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Mendelian Randomisation Study of Childhood BMI and Early Menarche by Hannah S. Mumby, Cathy E. Elks, Shengxu Li, Stephen J. Sharp, Kay-Tee Khaw, Robert N. Luben, Nicholas J. Wareham, Ruth J. F. Loos, Ken K. Ong

“…To infer the causal association between childhood BMI and age at menarche, we performed a mendelian randomisation analysis using twelve established “BMI-increasing” genetic variants as an instrumental variable (IV) for higher BMI. …”
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Effects of Providing Enrichment to Broilers in an Animal Welfare Environment on Productivity, Litter Moisture, Gas Concentration (CO₂ and NH₃), Animal Welfare... by Chan-Ho Kim, Woo-Do Lee, Ji-Seon Son, Jung-Hwan Jeon, Se-Jin Lim, Su-Mi Kim

“…Among these, environmental enrichment methods are effective in reducing stress and creating a welfare-friendly rearing environment, but there are few cases of actual application to farms. Therefore, we aimed to investigate the effect of providing pecking materials (grain blocks), known as one of the environmental enrichment methods, to commercial broiler farms. …”
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Adsorptive Removal of Copper by Using Surfactant Modified Laterite Soil by Tien Duc Pham, Hoang Hiep Nguyen, Ngoc Viet Nguyen, Thanh Tu Vu, Thi Ngoc Mai Pham, Thi Hai Yen Doan, Manh Ha Nguyen, Thi Mai Viet Ngo

“…Based on adsorption isotherms, surface charge effects, and surface modification, we suggest that the adsorption mechanism of Cu2+ onto SML was induced by electrostatic attraction between Cu2+ and the negatively charged SML surface and nonelectrostatic interactions between Cu2+ and organic substances in the laterite.…”
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Seasonal Dynamics of Sand Flies (Diptera, Pshycodidae), Vectors of Cutaneous Leishmaniasis, in the City of Fez, Northern Morocco by Najoua Darkaoui, Abdellatif Janati Idrissi, Fatima Zahra Talbi, Youness El Fattouhi, Hajar El Omari, Mohamed Najy, Abdelkarim Taam, Abdellatif Alami, Fouad El-Akhal, Abdelhakim El Ouali Lalami

“…The seasonal fluctuation of sand flies could be conditioned by climatic factors where the period of activity of the species coincides with the hot months (May, June, July, and August). We have observed that the temperature factor favors the prevalence of sand flies, while the difference in the relative abundance of species between the sites is related to the difference in the bioecological conditions of each site.…”
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Impact of hypertension on liver fibrosis in patients with metabolic dysfunction-associated fatty liver disease by Zhifeng Gao, Huan Deng, Bowen Qin, Liang Bai, Jiangwei Li, Jian Zhang

“…BackgroundThis study aims to evaluate the association between hypertension and the risk of fibrosis in metabolic dysfunction–associated steatotic liver disease (MASLD) patients, as well as to investigate the impact of hypertension on the progression of liver fibrosis within this population.MethodsWe utilized data from the NHANES 2017 to March 2020. …”
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Can growth in captivity alter the calcaneal microanatomy of a wild ungulate? by Cottereau, Romain, Ortiz, Katia, Locatelli, Yann, Houssaye, Alexandra, Cucchi, Thomas

“…Using the calcaneus as a phenotypic marker through qualitative and quantitative 3D microanatomical analyses, we relied on a comparative study across wild boars (Sus scrofa) populations from controlled experimental conditions with different mobility patterns (natural habitat, large pen, and stall) and archaeological specimens collected from middle and late Mesolithic as surrogate for the norm of reaction in European wild boar phenotype before the spread of agriculture and domestic pigs. …”
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Mobile Phone App to Promote Lifestyle Change in People at Risk of Type 2 Diabetes: Feasibility 3-Arm Randomized Controlled Trial by Gyri Skoglund, Gunvor Hilde, Pernille Lunde, Venessa Vera Cruz Naceno, Cecilie Fromholt Olsen, Birgitta Blakstad Nilsson

“… Abstract BackgroundThe use of mobile health interventions, such as apps, are proposed to meet the challenges faced by preventive health care services due to the increasing prevalence of type 2 diabetes (T2D). Thus, we developed and conducted initial feasibility testing of the Plunde app for promoting and monitoring individual goals related to lifestyle change for people at risk of T2D. …”
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Factors influencing survival outcomes in patients with stroke at three tertiary hospitals in Zimbabwe: A 12-month longitudinal study. by Farayi Kaseke, Lovemore Gwanzura, Cuthbert Musarurwa, Elizabeth Gori, Tawanda Nyengerai, Timothy Kaseke, Aimee Stewart

“…<h4>Background</h4>In this longitudinal study, we aimed to determine factors influencing survival outcomes among patients with stroke at three tertiary hospitals over a 12-month period. …”
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Fever, Haematuria, and Acute Graft Dysfunction in Renal Transplant Recipients Secondary to Adenovirus Infection: Two Case Reports by J. Ramírez, I. C. Bostock, A. Martin-Onraët, S. Calleja, A. Sánchez-Cedillo, L. A. Navarro-Vargas, A. L. Noriega-Salas, O. Martínez-Mijangos, N. O. Uribe-Uribe, M. Vilatoba, B. Gabilondo, L. E. Morales-Buenrostro, J. Alberú

“…We report two cases of adenoviral infection in kidney transplant recipients that presented with different clinical characteristics under similar demographic and posttransplant conditions. …”
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Genotyped cluster investigations versus standard contact tracing: comparative impact on latent tuberculosis infection cascade of care in a low-incidence region by Michael Asare-Baah, Marie Nancy Séraphin, LaTweika A.T. Salmon-Trejo, Lori Johnston, Lina Dominique, David Ashkin, Krishna Vaddiparti, Awewura Kwara, Anthony T. Maurelli, Michael Lauzardo

“…Although genotyped cluster investigations may be superior to contact investigations in generating additional epidemiological links, this may not necessarily translate into reducing infections. Here, we investigated the impact of genotyped cluster investigations compared to standard contact investigations on the LTBI care cascade in a low incidence setting. …”
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Severe pneumonia caused by Nocardia otitidiscaviarum in a patient with bronchiectasis and IgA nephropathy: a case report by Yi Lin, Zhao-Zhao Jiang, Xiao-Qian Chi, Jian-Sheng Chen, Chao Wen, Chao Zhang, Ying-Ying Wang, Guang-Liang Xie

“…BackgroundNocardia species are rare opportunistic pathogens in the clinic, with strong invasiveness and dissemination, that can cause serious pulmonary infection, especially in immunocompromised patients, chronic lung diseases and hormone use, and is easy to be missed and misdiagnosed, preventing patients from obtaining timely and effective treatment, resulting in a high mortality rate.Case presentationHere, we present a rare case of a patient with chronic bronchiectasis and IgA nephropathy who developed Nocardia otitidiscaviarum pneumonia shortly after hormone therapy. …”
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Clear Cell Carcinoma Arising from Cesarean Section Scar Endometriosis: Case Report and Review of the Literature by Sakura Ijichi, Taisuke Mori, Izumi Suganuma, Takuro Yamamoto, Hiroshi Matsushima, Fumitake Ito, Makoto Akiyama, Izumi Kusuki, Jo Kitawaki

“…The therapeutic strategy has not been determined because of the limited cases. We report a case of clear cell adenocarcinoma arising in the abdominal wall from endometriosis tissues following cesarean section and review previous literature to achieve the optimal treatment and better prognosis. …”
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Prediction of the risk of 3-year chronic kidney disease among elderly people: a community-based cohort study by Tao Wang, Zhitong Zhou, Longbing Ren, Zhiping Shen, Jue Li, Lijuan Zhang

“…Objective We conducted a community-based cohort study to predict the 3-year occurrence of chronic kidney disease (CKD) among population aged ≥60 years.Method Participants were selected from two communities through randomized cluster sampling in Jiading District of Shanghai, China. …”
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Correlations among PPAR𝜸, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer by Valerio Pazienza, Francesca Tavano, Giorgia Benegiamo, Manlio Vinciguerra, Francesca Paola Burbaci, Massimiliano Copetti, Fabio Francesco di Mola, Angelo Andriulli, Pierluigi di Sebastiano

“…Emerging evidence indicates that peroxisome proliferator-activated receptor γ (PPARγ) and DNA methyltransferases (DNMTs) play a role in carcinogenesis. In this study we aimed to evaluate the expression of PPARγ, DNMT1, and DNMT3B and their correlation with clinical-pathological features in patients with pancreatic cancer (PC), and to define the effect of PPARγ activation on DNMTs expression in PC cell lines. qRT-PCR analysis showed that DNMT3B expression was downregulated in tumors compared to normal tissues (𝑃=0.03), whereas PPARγ and DNMT1 levels did not show significant alterations in PC patients. …”
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Is platelet-rich plasma better than steroids as epidural drug of choice in lumbar disc disease with radiculopathy? Meta-analysis of randomized controlled trials by Sathish Muthu, Sathish Muthu, Sathish Muthu, Vibhu Krishnan Viswanathan, Vibhu Krishnan Viswanathan, Prakash Gangadaran, Prakash Gangadaran, Prakash Gangadaran

“…The current meta-analysis was performed to analyze the efficacy and safety of platelet-rich plasma (PRP) as an epidural injectate, in comparison with steroids in the management of radiculopathy due to lumbar disc disease (LDD). We conducted independent and duplicate searches of the electronic databases (PubMed, Embase and Cochrane Library) in March 2024 to identify randomized controlled trials (RCTs) analyzing the efficacy of epidural PRP for pain relief in the management of LDD. …”
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7,12-Dimethylbenz(a)anthracene as a Model for Ovarian Cancer Induction in Rats by Ana Carolina Ciseski Gonçalves, Katia Candido Carvalho, José Antônio Orellana Turri, Ricardo dos Santos Simões, Jesus Paula Carvalho, Luiz Fernando Ferraz da Silva, José Maria Soares Júnior, Edmund Chada Baracat

“…The results were all similar: regardless of the dose, administration route, animal strain, or induction time, the induction rate of ovarian tumors was always high, reinforcing the role of DMBA as an effective inducer of ovarian carcinogenesis. We conclude that ovarian carcinogenesis can be studied using DMBA as an inducer in rat and mouse models with a long time range for tumor establishment (at least 110 days) and a high rate of mortality. …”
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