Delayed Postoperative Epidural Hematoma Presenting Only with Vesicorectal Disturbance by Hiroto Kamoda, Tetsuhiro Ishikawa, Masayuki Miyagi, Yawara Eguchi, Sumihisa Orita, Miyako Suzuki, Yoshihiro Sakuma, Yasuhiro Oikawa, Kazuyo Yamauchi, Gen Inoue, Kazuhisa Takahashi, Seiji Ohtori

“…We present a rare case of delayed onset of epidural hematoma after lumbar surgery whose only presenting symptom was vesicorectal disturbance. …”
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Maternal and neonatal outcomes of Group B Streptococcus colonization: a retrospective study by Guixiu Jin, Lanhua Liu, Xiaolong Wang, Junling Fei, Zhenling Zhu, Ziyan Jiang, Min Liu

“…Fetal distress (OR, 1.940; 95% CI, 1.355 to 2.778, P < 0.001), neonatal sepsis (OR, 5.063; 95% CI, 2.536–10.109, P < 0.001), low Apgar scores (OR, 2.097; 95% CI, 1.184–3.715, P = 0.011), neonatal pneumonia (OR, 1.638; 95% CI, 1.039 to 2.582, P = 0.034) and neonatal hyperbilirubinemia (OR, 1.438; 95% CI, 1.080 to 1.915, P = 0.013) were significantly related to maternal GBS colonization. When we used the composite adverse neonatal outcomes as the dependent variable and analyzed the influencing factors, the logistic regression analysis revealed that GBS colonization was still significantly related to an elevated risk of adverse neonatal outcomes (OR = 1.752, 95% CI, 1.389–2.208; P < 0.001). …”
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A within-person investigation of recovery identity following substance use disorder: examining the impact of recovery-focused social contexts by Joseph H. Lancaster, Hannah B. Apsley, Timothy R. Brick, Timothy R. Brick, H. Harrington Cleveland

“…Because recovery-focused social contexts exist to support individuals’ recovery wellbeing, we assessed the moderating impact of two such contexts (recovery community centers [RCCs] and recovery meetings) as same-day moderators.Methods and materials91 RCC visitors across Pennsylvania completed daily diary surveys for 10 evenings. …”
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Effect of Treatment Delay, Stroke Type, and Thrombolysis on the Effect of Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome after Acute Stroke: A Systematic Review and Meta-Ana... by Philip M. Bath, Lisa Woodhouse, Kailash Krishnan, Craig Anderson, Eivind Berge, Gary A. Ford, Thompson G. Robinson, Jeffrey L. Saver, Nikola Sprigg, Joanna M. Wardlaw, Blood pressure in Acute Stroke Collaboration (BASC)

“…Nitric oxide (NO) donors are a candidate treatment for acute stroke and two trials have suggested that they might improve outcome if administered within 4–6 hours of stroke onset. We assessed the safety and efficacy of NO donors using individual patient data (IPD) from completed trials. …”
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Global Distribution and Projected Variations of Compound Drought‐Extreme Precipitation Events by Siqi Deng, Dongsheng Zhao, Ziwei Chen, Lei Liu, Yu Zhu, Ke Wang, Xuan Gao, Hanqian Wu, Du Zheng

“…Yet few studies have analyzed the likelihood of CDEP at different time intervals and their potential variations under global warming. In this study, we assessed the coincidence rate between droughts and extreme precipitation events at 1‐month (CDEP‐1), 2‐month (CDEP‐2), and 3‐month (CDEP‐3) intervals, as well as their potential changes in a 1.5 and 2°C warming world (under both SSP2‐4.5 and SSP5‐8.5 scenarios). …”
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Genetically edited human placental organoids cast new light on the role of ACE2 by Anya L. Arthurs, Bianca Dietrich, Martin Knöfler, Caleb J. Lushington, Paul Q. Thomas, Fatwa Adikusuma, Jessica M. Williamson, Susan Babikha, Tyla Damhuis, Tanja Jankovic-Karasoulos, Melanie D. Smith, Kirsty G. Pringle, Claire T. Roberts

“…Parameters of cell and organoid growth were measured, together with qPCR, Western Blotting, and ELISA assessments, in all groups from both organoid models. Here, we report that ACE2 knockout results in delayed placental cell growth and increased cell death. …”
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METTL14-mediated m6A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis by Dan Li, Li Qian, Yufeng Du, Lifang Liu, Ziyue Sun, Yongkang Han, Xiangrui Guo, Chao Shen, Zheng Zhang, Xuejun Liu

“…The expressions of identified m6A regulator and target gene were validated using MeRIP-qPCR and real-time PCR. Moreover, we established an animal model and a senescent model of A549 cells to explore the associated molecular mechanism. …”
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Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study by Giorgio Bedogni, Roberto Berni Canani, Laura Carucci, Rita Nocerino, Serena Coppola, Pasqualina Capasso, Veronica Giglio

“…Background We aimed at identifying the factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA), a group of common paediatric conditions including food protein–induced: enteropathy (FPE), allergic proctocolitis (FPIAP), enterocolitis syndrome (FPIES), and motility disorders (FPIMD).Methods Prospective multicentre cohort study involving paediatric patients (both sexes, aged ≤14 y) with non-IgE-GIFA diagnosed and followed for 24 months at a Tertiary Centre for Paediatric Allergy, Gastroenterology and Nutrition. …”
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Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) by Fekete, Zsófia, Absolon, Dominic E., Michell, Craig, Wood, Jonathan M. D., Goffart, Steffi, Pohjoismäki, Jaakko L. O.

“…We present here a high-quality genome assembly of a male mountain hare (Lepus timidus Linnaeus), from Ilomantsi, Eastern Finland, utilizing an isolated fibroblast cell line as the source for high quality DNA and RNA. …”
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Using CT imaging to identify sarcopenia as a risk factor for severe falls in older adults by Nadja Fries, Angeliki Kotti, Mischa Woisetschläger, Anna Spångeus

“…The purpose of the present study was to investigate risk factors, including sarcopenia, for severe falls compared to non-severe falls. In addition, we wanted to explore possible associations between sarcopenia, bone mineral density (BMD), adipose tissue as well as clinical scores assessing frailty, nutritional status, and fall risk. …”
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Efficient continuous SF6/N2 separation using low-cost and robust metal-organic frameworks composites by Jinjian Li, Yuting Chen, Tian Ke, Yuanyuan Jin, Rongrong Fan, Guihong Xu, Liu Yang, Zhiguo Zhang, Zongbi Bao, Qilong Ren, Qiwei Yang

“…Herein, with insights into in-pore chemistry and industrial process design, we report a systematic investigation that constructed two low-cost composites pellets (Al(fum)@2%HPC and Al(fum)@5%Kaolin) coupled with an innovative two-stage Vacuum Temperature Swing Adsorption (VTSA) process for the ultra-efficient recovery of low-concentration SF6 from N2. …”
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L’agriculture itinérante sur brûlis, une menace sur la forêt tropicale humide ? by Serge Bahuchet, Jean-Marie Betsch

“…The perception of the agriculture on slash-and-burn field by the majority of agronomists and ecologists is so uniformly negative: archaic, destructive for the forest, unproductive, dangerous even for the future of the planet.Another logical reference, the durability of the practices, must be investigated: in agriculture, the durability must be economically viable, socially acceptable and ecologically solid (Conway 1987) that we can translate by the capacity of an agroecosystem to maintain a stable long-term production based on an ecological, social and economic solidity/validity. …”
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Study protocol for the development and pilot-testing of a Self-assessment tool for the implementation of the European Standards of Care for Newborn Health (ESCNH) by James Webbe, Helmut Hummler, Luc J I Zimmermann, Ylva Thernström Blomqvist, Nicholas Lack, Dietmar Schlembach, Julia Hoffmann, Silke Mader, Eleni Vavouraki, Sarah Lehmann, Gina Ancora, Esther Schouten, Ilaria Simonelli, Isabel Geiger

“…Such a tool should help identify areas in need of improvement and provide clear recommendations for action. We aim to develop a digital self-assessment tool for HCPs to detect the local level of ESCNH fulfilment and identify areas in need of improvement, and thus provide recommendations for action.Methods and analysis The self-assessment tool will have the form of a digital questionnaire with condensed ESCNH content. …”
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Visible and rapid detection of feline chaphamaparvovirus using multienzyme isothermal rapid amplification and lateral flow dipstick assay by Jun Ji, Xinhao Mu, Shunshun Pan, Xin Xu, Shiyuan Zhang, Honghui Huang, Ying Li, Yingzuo Bi, Lunguang Yao

“…Feline chaphamaparvovirus (FeChPV) is a novel parvovirus previously reported in Canadian cats and Chinese dogs with diarrhea in 2019 and 2020, respectively. Herein, we aimed to establish a simple detection method for FeChPV in field clinics. …”
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A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study by Rong Lin, Yuanjiao Yan, Zhili Chen, Chenshan Huang, Junyu Zhao, Mingfeng Chen, Hong Li

“…Subjective cognitive decline (SCD) is present in > 50% of older adults and associated with progression to dementia. Here, we tested the compliance and effectiveness of a Multidomain Lifestyle Intervention Program using the mini-program, Cognitive Evergreenland, (MLIP-CE), based on the Health Action Process Approach model to support home-based intervention in older adults with SCD. …”
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Determination of the breeding value of collection chickpea (<i>Cicer arietinum</i> L.) accessions by cluster analysis by N. A. Vus, L. N. Kobyzeva, O. N. Bezuglaya

“…Based on the data obtained, we concluded that the accessions of cluster 1 were preferable in breeding programs to develop chickpea varieties for the forest-steppe zone.…”
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‘Gaedhilg Chúige Uladh a shábhailt’: An phleanáil teanga in An tUltach [‘Gaedhilg Chúige Uladh a shábhailt’: Language planning in An tUltach] by Duane Long

“…It would appear that An tUltach was founded with the purpose of focusing on corpus planning as the first edition sought contributors through an open call for writers and states that a concerted attempt will be made to put Irish into books (“a chur síos i leabhraibh”). We also see, however, an eye towards acquisition planning with a teachers’ page (“Leathanach na Múinteoirí”) appearing frequently in the journal’s early years. …”
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Acidity, sugar, and alcohol contents during the fermentation of Osmanthus-flavored sweet rice wine and microbial community dynamics by Ping Tian, Jiaqiong Wan, Tuo Yin, Li Liu, Hongbing Ren, Hanbing Cai, Xiaozhen Liu, Hanyao Zhang

“…In this study, the dynamic changes in sugar level, acidity, alcohol content, microbial community composition, and microbial metabolic pathways during traditional fermentation of OFSRW at four-time points—0 h (AG0), 24 h (AG24), 36 h (AG36), and 43 h (AG43)—were analyzed via direct titration, total acid assays, alcoholometry, and high-throughput macrogenomic techniques. First, we found that bacteria were the dominant microorganisms in the early stage of OFSRW fermentation (AG0), fungi were the dominant microorganisms in the middle and late stages of fermentation (AG24 and AG36), and Rhizopus was the main fungal genus throughout fermentation. …”
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The vestibular and oculomotor dysfunction in Fabry disease: a cohort study in China by Yinglin Leng, Yawen Zhao, Hong Zhou, Xia Ling, Xia Wang, Guiping Zhao, Wei Zhang

“…Objective Whereas a few studies have evaluated vestibular involvement in Fabry disease (FD), the relationship between vestibular/oculomotor abnormalities and disease-specific biomarkers remain unclear. Therefore, we seek to evaluate these quantitatively and analyze their relationship with disease phenotype and biomarkers in FD.Methods This cohort study enrolled 37 Chinese FD patients registered in our center. …”
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C5a/C5aR regulates Th1/Th2 imbalance in sepsis-associated lung injury by promoting neutrophil activation to increase PAD4 expression by Zhenbing Lu, Ling Zhu, Changlin Yi, Bi Su, Renying Wang

“…Additionally, GSK484 intervention on Th1 cell phenotype further affected lung epithelial cell injury.Conclusion In summary, we revealed the mechanism of C5a/C5aR-induced PAD4 upregulation via neutrophil activation in sepsis-associated lung injury, causing a Th1/Th2 imbalance and lung injury, providing a novel approach for sepsis-associated lung injuries treatment.…”
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