Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma by Yuli Jian, Kangkang Yang, Jinjing Li, Ling Tang, Guang Zeng, Xiaoxin Sun, Xiao Yu, Abdullah Al-danakh, Qiwei Chen, Deyong Yang, Shujing Wang

“…In the study, through systematic bioinformatics analysis and experimental verification, we demonstrated that ST3Gal5 expression was elevated in tumor tissues of KIRC patients, correlating with poor prognosis, and ST3Gal1 was downregulated and associated with a better prognosis. …”
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Failure Mechanism and Control Technology of Thick and Soft Coal Fully Mechanized Caving Roadway under Double Gobs in Close Coal Seams by Shengrong Xie, Xiaoyu Wu, Dongdong Chen, Yaohui Sun, En Wang, Xiaowei Wu, Xiaobo Duan, Zaisheng Jiang, Pengyu Qi, Songhao Shi

“…A laboratory test was used to monitor the strength of the grouting test block of the broken coal body. Then, we proposed that grouting anchor cable be used to strengthen the weak surface of the roof and block the roof cracks. …”
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Microbial Decontamination of Onion by Corona Discharge Air Plasma during Cold Storage by Eun Ha Chang, Yeoung Seuk Bae, Il Sheob Shin, Hyun Jin Choi, Ji Hyun Lee, Ji Weon Choi

“…Corona discharge air plasma (CDAP) is a nonthermal decontamination technology which is generating antimicrobial agents such as photons, electrons, positively and negatively charged ions, atoms, and free radicals. We investigated the effect of a corona discharge under atmospheric pressure on the sterilization of postharvest fungal pathogens on onion. …”
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Socioeconomic inequality in hypertension and its determinants in people over 60 years in Fasa, southern Iran: a Blinder-Oaxaca decomposition by Reza Tabrizi, Reza Pakzad, Maryam Akbari, Azizallah Dehghan, Mozhan Abdollahi, Sina Bazmi, Sina Kardeh, Yaser Sarikhani

“…Methods A total of 1,632 seniors, aged 60 and above, were included in the analysis, with data obtained from the Fasa Adults Cohort Study (FACS). Initially, we utilized both simple and multiple logistic regression models to investigate the associations between HTN and the determinant variables. …”
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A physically-based formulation for texture evolution during dynamic recrystallization. A case study of ice by Chauve, Thomas, Montagnat, Maurine, Dansereau, Véronique, Saramito, Pierre, Fourteau, Kévin, Tommasi, Andréa

“…However, this prediction remains a challenge.We propose a new formulation for modeling texture evolution due to dynamic recrystallization on the basis of observations of the evolution of the microstructure and texture of ice deforming by dislocation creep and dynamic recrystallization. …”
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Decoding the anomalies: a genome-based analysis of Bacillus cereus group strains closely related to Bacillus anthracis by Thuto Gomolemo Magome, Marius Surleac, Marius Surleac, Ayesha Hassim, Cornelius Carlos Bezuidenhout, Henriette van Heerden, Kgaugelo Edward Lekota

“…This study supports the existing nomenclature framework which offers an effective solution for classifying species into genomospecies groups. We recommend isolates with ANI ≥99% to standard reference B. anthracis be designated as typical B. anthracis in GenBank to maintain taxonomic clarity and precision.…”
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Competing health risks associated with the COVID-19 pandemic and early response: A scoping review. by Stefan Baral, Amrita Rao, Jean Olivier Twahirwa Rwema, Carrie Lyons, Muge Cevik, Anna E Kågesten, Daouda Diouf, Annette H Sohn, Refilwe Nancy Phaswana-Mafuya, Adeeba Kamarulzaman, Gregorio Millett, Julia L Marcus, Sharmistha Mishra

“…While these interventions have focused on testing, treatment, and mitigation of COVID-19, there have been reports of interruptions to diagnostic, prevention, and treatment services for other public health threats.<h4>Objectives</h4>We conducted a scoping review to characterize the early impact of COVID-19 on HIV, tuberculosis, malaria, sexual and reproductive health, and malnutrition.…”
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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling by Xian Jin, Liang Liu, Yaping Zhang, Yin Xiang, Guizhi Yin, Yi Lu, Ludong Shi, Jian Dong, Chengxing Shen

“…In vitro, when the monocytes were treated with different dosages of AGEs (50, 150, and 300 μg/mL), we found that proliferation (CCK8) but not apoptosis (FCM) of the monocytes was induced; the mRNA expressions of proinflammatory cytokines (IL-1β and TNF-α) and GM-CSF were upregulated in a dose-dependent manner while mRNA levels of IL-10 and M-CSF were changed much less in monocytes (real-time PCR). …”
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Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics by George S. Biggs, Emma E. Cawood, Aini Vuorinen, William J. McCarthy, Harry Wilders, Ioannis G. Riziotis, Antonie J. van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J. Powell, David House, Simon J. Boulton, J. Mark Skehel, Katrin Rittinger, Jacob T. Bush

“…Screening libraries of reactive fragments by chemoproteomics offers a compelling approach to ligand discovery, however, optimising sample throughput, proteomic depth, and data reproducibility remains a key challenge. We report a versatile, label-free quantification proteomics platform for competitive profiling of cysteine-reactive fragments against the native proteome. …”
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3,5,6,7,8,3’,4’- Heptamethoxyflavonoid inhibits TGF-β1-induced epithelial–mesenchymal transition by regulating oxidative stress and autophagy through MEK/ERK/PI3K/AKT/mTOR signalin... by Yiting Wang, Zhiheng Ma, Weiwen Peng, Qinglian Yu, Wenjie Liang, Liu Cao, Zhuqiang Wang

“…Meanwhile, the expression level of E-cadherin increased as an epithelial cell marker. Additionally, we discussed the effects of HMF on oxidative stress and autophagy. …”
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Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea by Zishen Lin, Yue Feng, Jinping Wang, Zhaoyue Men, Xi Ma

“…In vitro, important gene involved in the reduction of BA disorder induced-diarrhea were screened by RNA transcriptomics sequencing, and activation pathway of FXR-SIRT1-LKB1 to alleviate BA disorder diarrhea and P53-mediated apoptosis were proposed in vitro by multifarious siRNA interference, CO-IP, immunofluorescence, and so on, which mechanism was also verified in a variety of mouse models. Results Here, we reveal for the first time that core microbiota derived I3C represses gut epithelium glucuronidation, particularly 3β-glucuronic CDCA production, which reaction is mediated by host UDP glucuronosyltransferase family 1 member A4 (UGT1A4) and necessary of BA disorder induced diarrhea. …”
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Plasma galectin-3 is associated with decreased glomerular filtration rate in chronic HIV by Diana L. Vares-Lum, Louie Mar A. Gangcuangco, Juwon Park, Eduardo Manzano, Michael Ortega, Dominic C. Chow, Cecilia Shikuma

“…The pathogenesis of CKD in HIV remains poorly understood but is likely from a combination of various factors, such as traditional comorbidities, prolonged antiretroviral therapy, immune dysregulation, and direct HIV effect on the kidneys. We evaluated plasma galectin-3 (Gal-3), a circulating marker of fibrosis, and its association with renal function. …”
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Defining and measuring long COVID fatigue: a scoping review by Deborah Edwards, Jennifer Davies, Christine Bundy, Rachael Pattinson, Bethan Thomas, Carys Dale, Benjamin Jenkins, Helena Lande

“…There is an urgent need to better understand long COVID fatigue and to identify the different mechanisms involved. In order to do this, we need consistency with the language around fatigue and its measurement within research and across disciplines.Review registration The protocol has been registered on Open Science Framework (https://doi.org/10.17605/OSF.IO/HNF8Z).…”
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Aerobic capacity and muscle proteome: Insights from a mouse model by Abel Plaza‐Florido, Alejandro Santos‐Lozano, Susana López‐Ortiz, Beatriz G. Gálvez, Joaquín Arenas, Miguel A. Martín, Pedro L. Valenzuela, Tomàs Pinós, Alejandro Lucia, Carmen Fiuza‐Luces

“…Abstract We explored the association between aerobic capacity (AC) and the skeletal muscle proteome of McArdle (n = 10) and wild‐type (n = 8) mice, as models of intrinsically ‘low’ and ‘normal’ AC, respectively. …”
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A comparative study on the efficacy of kirschner wire tension band combined with anchor cross-suture internal fixation versus partial patellectomy in the treatment of comminuted in... by Siyu Duan, Rongda Xu, Hanfei Liu, Ming Sun, Hairui Liang, Zhencun Cai

“…Methods A retrospective analysis was conducted on 14 patients who underwent Kirschner wire tension band combined with anchor cross-suture fixation (Group A) in our department of orthopedics from September 2020 to April 2022. Additionally, we matched 14 patients with similar baseline characteristics who received inferior pole patellectomy combined with patellar tendon repair (Group B). …”
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Evaluation of sex-based differences in below-the-knee plaque histology in patients who underwent amputation for chronic limb-threatening ischemia by Fouzul Kansul, Deborah Vela, MD, Judit Csore, MD, Bright Benfor, MD, Sasha Suarez, MD, Anahita Dua, MD, MBA, MSC, Trisha L. Roy, MD, PhD

“…Methods: A total of 35 lower limbs were collected from 34 patients with end-stage PAD undergoing major amputation. We selected, harvested, and cross-sectioned at 3- to 4-mm intervals 163 diseased below-the-knee arterial segments resulting in 1260 arterial rings. …”
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Relapsing Campylobacter jejuni Systemic Infections in a Child with X-Linked Agammaglobulinemia by Paola Ariganello, Giulia Angelino, Alessia Scarselli, Irene Salfa, Martina Della Corte, Arianna De Matteis, Patrizia D'Argenio, Susanna Livadiotti, Emma C. Manno, Cristina Russo, Andrea Finocchi, Caterina Cancrini

“…Recurrent infections are the main clinical manifestations; although they are especially due to encapsulated bacteria, a specific association with Campylobacter species has been reported. Here, we report the case of a boy with XLA who presented with relapsing Campylobacter jejuni systemic infections. …”
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Prevalence and investigation of Cytomegalovirus (HCMV) in blood donors from the main blood establishment in Rio de Janeiro/Brazil by Agildo da Silva Oliveira, Jéssica Gonçalves Pereira, Gabrielle Tantos Nunes, Ivanildo Pedro de Sousa Junior, Dmitry José de Santana Sarmento, Josiane Iole França Lopes, Luiz Amorim Filho, Vanessa Salete de Paula

“…Materials and methods: Here, we investigated the serological and molecular prevalence of HCMV among 980 blood donors from the main blood bank in Rio de Janeiro, Brazil, using chemiluminescence and real-time PCR (TaqMan). …”
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Safety and efficacy of sugammadex in management of patients with myasthenia gravis undergoing general anesthesia: A systematic review by Alan D. Kaye, Emily A. Villafarra, Erin S. Everett, Erin E. Ware, Sydney A. Mashaw, William D. Brouillette, Camille G. Elder, Taylor Moss, Luke Muiznieks, Edwin Herron, Shahab Ahmadzadeh, Sahar Shekoohi

“…Objective: The objective of this study was to analyze available evidence on efficacy and safety of sugammadex in reversing neuromuscular blockades in patients with Myasthenia Gravis (MG), thereby providing a comprehensive understanding of its potential benefits and risks in this specific patient population. Methods: We performed a systematic search for studies from PubMed, Embase, Web of Science, and Google Scholar. …”
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Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital by Ieva Renata Jonaitytė, Vita Karpavičiūtė, Gediminas Kiudelis, Juozas Kupčinskas, Laimas Jonaitis

“…Erratum note The title, author's name, and abstract have been updated to reflect the correct information following a typographical error during typesetting. We apologize for any inconvenience caused by these errors. …”
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