Risk factors for fear of falling in stroke patients: a systematic review and meta-analysis by Li Ma, Qi Xie, Juhong Pei, Ling Gou, Yabin Zhang, Juanping Zhong, Yujie Su, Xinglei Wang, Xinman Dou

“…Objective Even though 32%–83% for fear of falling (FoF) in patients with stroke, very little is known about the predictors of the problems. Therefore, we systematically reviewed the literature on risk factors for FoF in patients with stroke.Design A systematic review and meta-analysisData sources PubMed, Embase, Cochrane Library database, Web of Science, CINAHL, PsycINFO, Grey literature and other relevant databases for related publications were searched (from inception to 17 July 2021).Results Eight studies involving 1597 participants were selected to analyse risk factors for patients with stroke with FoF. …”
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Synergic Involvements of Microorganisms in the Biomedical Increase of Polyphenols and Flavonoids during the Fermentation of Ginger Juice by Christian Aimé Kayath, Armel Ibala Zamba, Saturnin Nicaise Mokémiabeka, Meddy Opa-Iloy, Paola Sandra Elenga Wilson, Moïse Doria Kaya-Ongoto, Rodd Jurah Mouellet Maboulou, Etienne Nguimbi

“…Together with Saccharomyces cerevisiae, we showed that Bacillus sp. are able to secrete enzymatic landscape with some activities up to 50% including cellulase, amylase, pectinase, and protease.…”
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Beyond BRAFV600E: Investigating the Clinical and Genetic Spectrum of Langerhans Cell Histiocytosis in Children by Xue Tang, Ju Gao, Xia Guo, Zhi Wan, Jing‐jing Sun

“…Methods This study presented data on 33 pediatric LCH patients treated at our center who exhibited various molecular alterations other than the BRAFV600E mutation. Additionally, we comprehensively reviewed pediatric LCH cases with non‐BRAFV600E molecular alterations reported from January 2010 to August 2024. …”
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A model-based factorization method for scRNA data unveils bifurcating transcriptional modules underlying cell fate determination by Jun Ren, Ying Zhou, Yudi Hu, Jing Yang, Hongkun Fang, Xuejing Lyu, Jintao Guo, Xiaodong Shi, Qiyuan Li

“…While current manifold-learning methods provide insights into cell fate by inferring graph-based trajectory at cell level, challenges remain to retrieve interpretable biology underlying the diverse cellular states. Here, we described MGPfactXMBD, a model-based manifold-learning framework and capable to factorize complex development trajectories into independent bifurcation processes of gene sets, and thus enables trajectory inference based on relevant features. …”
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Context effects on repair of 5′‐overhang DNA double‐strand breaks induced by Cas12a in Arabidopsis by Sébastien Lageix, Miguel Hernandez, Maria E. Gallego, Jérémy Verbeke, Yannick Bidet, Sandrine Viala, Charles I. White

“…Abstract Sequence‐specific endonucleases have been key to the study of the mechanisms and control of DNA double‐strand break (DSB) repair and recombination, and the availability of CRISPR‐Cas nucleases over the last decade has driven rapid progress in the understanding and application of targeted recombination in many organisms, including plants. We present here an analysis of recombination at targeted chromosomal 5′ overhang DSB generated by the FnCas12a endonuclease in the plant, Arabidopsis thaliana. …”
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The Combination of Shading and Potassium Application Regulated the Bulb Active Ingredients Accumulation in <i>Fritillaria thunbergii</i> Miq. by Affecting Rhizosphere Microecology by Leran Wang, Bingbing Liang, Jia Liu, Huizhen Jin, Zixuan Zhu, Siyu Hao, Shumin Wang, Xiaoxiao Sheng, Xinshu Zhou, Honghai Zhu, Ning Sui

“…However, excessive pursuit of yield during cultivation has led to a decrease in medicinal ingredients. Therefore, we aimed to investigate the effects of two single-factor treatments, shading (SK0) and potassium application (S0K), and their coupling treatment (SK) on bulb biomass and medicinal substance content, along with the role of rhizosphere microorganisms. …”
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Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism by Daisuke Watanabe, Satoshi Morimoto, Noriko Morishima, Yoichiro Kato, Yoji Nagashima, Noriyuki Shibata, Atsuhiro Ichihara

“…This study investigated the significance of (P)RR and serum s(P)RR concentrations in patients with APA. We evaluated associations between (P)RR expression and expression of CYP11B2, an aldosterone synthase, and aldosterone production by the adrenal glands and assessed the relationships between serum s(P)RR concentration and background factors. …”
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PPAR Gamma Expression Levels during Development of Heart Failure in Patients with Coronary Artery Disease after Coronary Artery Bypass-Grafting by Izabela Wojtkowska, Andrzej Tysarowski, Katarzyna Seliga, Janusz A. Siedlecki, Zbigniew Juraszyński, Milosz Marona, Lidia Greszata, Anna Skrobisz, Karol Kaminski, Robert Sawicki, Janina Stępińska

“…The aim of study was to find the correlation between PPARγ expression during development of HF in patients and coronary artery disease (CAD) after coronary artery bypass-grafting (CABG). Methods and Results. We followed up 157 patients (mean age 63) with CAD without clinical, laboratory, or echo parameters of HF who underwent CABG. …”
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Comparative Genomic In Situ Hybridization and the Possible Role of Retroelements in the Karyotypic Evolution of Three Akodontini Species by Naiara Pereira Araújo, Gustavo Campos Silva Kuhn, Flávia Nunes Vieira, Thaís Queiroz Morcatty, Adriano Pereira Paglia, Marta Svartman

“…In order to shed some light on the cause of these rearrangements, we comparatively analyzed the karyotypes of three Akodontini species, Akodon cursor (2n = 14, FN = 19), A. montensis (2n = 24, FN = 42), and Necromys lasiurus (2n = 34, FN = 34), after GTG- and CBG-banding. …”
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Left ventricular output indices and sacubitril/valsartan titration: role of stroke volume index by Paolo Tolomeo, Ottavio Zucchetti, Emanuele D'Aniello, Noemi Punzo, Federico Marchini, Luca Di Ienno, Elisabetta Tonet, Rita Pavasini, Claudio Rapezzi, Gianluca Campo, Matteo Serenelli

“…Abstract Aims This study aims to investigate the role of echocardiographically determined left ventricular output indices on sacubitril/valsartan titration in a cohort of outpatients with heart failure and reduced ejection fraction (HFrEF). Methods and results We analysed 106 HFrEF patients who underwent echocardiography examination up to 1 week before starting treatment with sacubitril/valsartan. …”
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Blood Lead Levels among Blood Donors and High-Risk Occupational Groups in a Mining Area in Ghana: Implications for Blood Transfusion among Vulnerable Populations by Veronica Agyemang, Joseph K. Acquaye, Samuel B. E. Harrison, Felix B. Oppong, Stephany Gyaase, Kwaku P. Asante, Edeghonghon Olayemi

“…This study compared blood lead levels (BLL) among selected occupations at risk of lead exposure with healthy blood donors in nonexposed occupations in a Ghanaian mining area. We enrolled 40 participants each from the following high-risk occupational groups: small scale miners, painters/sprayers, drivers/fuel station attendants, and auto-mechanics as well as 40 healthy blood donors (made up of teachers, traders, and office workers). …”
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Predictors of Neurological and Functional Recovery in Patients with Moderate to Severe Ischemic Stroke: The EPICA Study by Manuel Murie-Fernández, Mercedes Molleda Marzo

“…Apart from demonstrating traditional “non-modifiable” predictors of outcome after stroke, like age, sex, and stroke severity, we also detected association between the use of dietary supplement MLC901 and recovery.…”
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Thermally tunable add-drop filter based on valley photonic crystals for optical communications by Sun Lu, Li Xingfeng, Hu Pan, Wang Hongwei, Zhang Yong, Tang Guojing, He Xintao, Dong Jianwen, Su Yikai

“…However, there are few studies on how to achieve power-efficient tunable devices based on VPCs, which are essential for implementing basic functions such as optical switching and routing. Here, we propose and experimentally demonstrate a thermally tunable add-drop filter (ADF) based on VPCs operating at telecommunication wavelengths. …”
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A new and automated risk prediction of coronary artery disease using clinical endpoints and medical imaging-derived patient-specific insights: protocol for the retrospective GeoCAD... by Louisa Jorm, Daniel Moses, Dona Adikari, Ramtin Gharleghi, Shisheng Zhang, Arcot Sowmya, Sze-Yuan Ooi, Susann Beier

“…The ‘anatomy of risk’ hypothesis recognises that adverse anatomical features of coronary arteries enhance atherogenic haemodynamics, which in turn mediate the localisation and progression of plaques. We propose a new risk prediction method predicated on CT coronary angiography (CTCA) data and state-of-the-art machine learning methods based on a better understanding of anatomical risk for CAD. …”
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Preterm Birth and Cardiometabolic Health Trajectories From Birth to Adulthood: The Avon Longitudinal Study of Parents and Children by Gemma L. Clayton, Laura D. Howe, Linda M. O'Keeffe, Adam J. Lewandowski, Deborah A. Lawlor, Abigail Fraser

“…Methods and Results Multilevel models were used to compare trajectories from early childhood (<9 years) to age 25 years of body mass index, fat and lean mass, systolic and diastolic blood pressure, lipids, glucose, and insulin, between individuals born preterm (N=311–676; range, 25–36 weeks’ gestation) and term (N=4973–10 534) in a UK birth cohort study. We also investigated gestational age as a continuum. …”
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The triglyceride–glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with... by Chenyang Li, Zixi Zhang, Xiaoqin Luo, Yichao Xiao, Tao Tu, Chan Liu, Qiming Liu, Cancan Wang, Yongguo Dai, Zeying Zhang, Cheng Zheng, Jiafeng Lin

“…The triglyceride–glucose (TyG) index and its derivatives (TyG–BMI, TyG–WC, and TyG–WHtR) have emerged as reliable IR markers. In this study, we evaluated their associations with all-cause and cardiovascular mortality in hypertensive patients using machine learning techniques. …”
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Evaluation of indirect indices in the insulin resistance assessment in patients with different body mass index by Lejla Čano Dedić, Arzija Pašalić, Emsel Papić, Emir Begagić, Sabina Šečić Selimović, Mario Gazibarić, Sabina Šegalo

“…Indirect indices based on mathematical models and derived from laboratory parameters have become increasingly popular in the past two decades. In this study, we evaluated their ability to predict IR in a population with different body mass index (BMI). …”
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Lead toxicity in Nicotiana tabacum L.: Damage antioxidant system and disturb plant metabolism by Tengfei Liu, Kai Zhang, Chunlan Ming, Jiashu Tian, Huanyu Teng, Zicheng Xu, Jiewang He, Fengfeng Liu, Yinghui Zhou, Jiayang Xu, Mohamed G. Moussa, Shenghua Zhang, Wei Jia

“…In this study, we treated tobacco seedlings with 0, 200, 400, and 800 mg/kg Pb2 +, and explored the response mechanism of tobacco under Pb stress through a combination of growth physiology and metabolomics analysis. …”
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Cranioplasty infection in porous hydroxyapatite: Potential antibacterial properties by Ismail Zaed, Corrado Iaccarino, Francesca Faedo, Laura Grillini, Elisabetta Galassi, Alessandro Dotti, Angelo Nataloni, Francesca Carolina Mannella, Andrea Cardia

“…Porous hydroxyapatite (PHA) is reported as a possible material for bone reconstruction, with good signs of biocompatibility, osteoconductive and osteointegrative properties. In the present paper we studied the possible antibacterial properties of PHA in a laboratory test in order to provide a possible overview of the occurrence of post-operative infections in PHA cranioplasty. …”
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Factors associated with risk analysis for asymptomatic left ventricular diastolic dysfunction in nondialysis patients with chronic kidney disease by Yajuan Gao, Shengnan Chen, Jiani Fu, Cui Wang, Yali Tang, Yongbai Luo, Xiaozhen Zhuo, Xueying Chen, Yan Shen

“…Therefore, exploring and intervention of the factors associated with risk for LVDD is of great importance in reducing the morbidity and mortality of cardiovascular disease (CVD) complications in CKD patients. We designed this retrospective cross-sectional study to collect clinical and echocardiographic data from 339 nondialysis CKD patients without obvious symptoms of HF to analyze the proportion of asymptomatic left ventricular diastolic dysfunction (ALVDD) and its related factors associated with risk by multivariate logistic regression analysis. …”
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