Efficacy of a new treatment algorithm for capsulitis of the fingers in rock climbers by Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Volker Rainer Schöffl, Christoph Lutter, Christoph Lutter, Hans-Christoph Lang, Mario Perl, Othmar Moser, Michael Simon

“…BackgroundAlthough finger joint capsulitis has been described among the most frequent injuries in climbers, no clinical studies on treatment strategies and outcomes are available.Study designProspective case series study.MethodsBetween 2015 and 2018 we prospectively treated 50 patients (38 male, 12 female) with a total number of 69 independent finger joint capsulitis according to a clinic specific treatment regimen and evaluated the outcome retrospectively. …”
Get full text

Relevance of anxiety in clinical practice of Guillain-Barré syndrome: a cohort study by Raphaël Porcher, Djillali Annane, Andrea Polito, Tarek Sharshar, Takoua Merhbene, Morgane Blanc, Marion Antona, Marie-Christine Durand, Diane Friedman, David Orlikowski, Marie-Hélène Marcadet

“…To address this issue, we assessed whether patient anxiety is associated with subsequent need for intubation in Guillain-Barré syndrome (GBS).Design Incident case-cohort study.Setting Acute secondary care in a teaching hospital (France) from 2006 to 2010.Participants 110 adult GBS patients. …”
Get full text

Identification of alterations in the nucleotide sequence of the chromatin remodeling gene PBRM1 in clear cell renal cell carcinoma patients by E. A. Klimentova, I. R. Gilyazova, A. A. Izmailov, I. M. Sultanov, M. A. Bermisheva, V. N. Pavlov, E. K. Khusnutdinova

“…Perhaps the low frequency of mutations in the samples we studied is due to the fact that the inactivation of the PBRM1 gene takes place in other ways, and may also be due to the ethno-specificity of the studied group of patients.…”
Get full text

Effectiveness of an Innovative Pulsed Electromagnetic Fields Stimulation in Healing of Untreatable Skin Ulcers in the Frail Elderly: Two Case Reports by Fabio Guerriero, Emanuele Botarelli, Gianni Mele, Lorenzo Polo, Daniele Zoncu, Paolo Renati, Carmelo Sgarlata, Marco Rollone, Giovannoi Ricevuti, Niccolò Maurizi, Matthew Francis, Mariangela Rondanelli, Simone Perna, Davide Guido, Piero Mannu

“…Pulsed electromagnetic fields (PEMFs) have proved to be a promising therapy for wound healing. Here we describe the first reported case of an innovative PEMF therapy, Emysimmetric Bilateral Stimulation (EBS), used to successfully treat refractory skin ulcers in two elderly and fragile patients. …”
Get full text

Association between fibrinogen-to-albumin ratio and bone metabolism markers (β-CTX and P1NP) in Chinese individuals with osteoporotic fracture: a cross-sectional investigation by Li-long Feng, Ke Lu, Chong Li, Min-zhe Xu, Yao-wei Ye, Yi Yin, Hui-qiang Shan

“…After accounting for several confounders, the independent connection between FAR levels and β-CTX and P1NP was investigated via Generalized Estimating Equations (GEE). On top of that, we used a generalized additive model (GAM) to find any non-linear correlations, and a two-piecewise linear regression model to find the threshold effects in the smoothing curves that came out of it. …”
Get full text

Response Time Threshold for Predicting Outcomes of Patients with Out-of-Hospital Cardiac Arrest by Ling Hsuan Huang, Yu-Ni Ho, Ming-Ta Tsai, Wei-Ting Wu, Fu-Jen Cheng

“…Ambulance response time is a prognostic factor for out-of-hospital cardiac arrest (OHCA), but the impact of ambulance response time under different situations remains unclear. We evaluated the threshold of ambulance response time for predicting survival to hospital discharge for patients with OHCA. …”
Get full text

Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis by Hayriye Tatlı Doğan, Mehmet Doğan, Seda Kahraman, Doğukan Çanakçı, Mehmet Ali Nahit Şendur, Mustafa Tahtacı, Fazlı Erdoğan

“…This study included 100 patients who underwent resection for colorectal cancer. We aimed to investigate the relationships between the expression status of the HIF-1α, LOX and ITGA5 proteins and clinicopathologic parameters. …”
Get full text

Machine learning-based analysis of sea fog’s spatial and temporal impact on near-miss ship collisions using remote sensing and AIS data by Dan Liu, Ling Ke, Zhe Zeng, Zhe Zeng, Shuo Zhang, Shanwei Liu, Shanwei Liu

“…Second, the geographically weighted regression model investigates spatial variations in the correlation between sea fog and near-miss collisions. Third, we perform the analysis for monthly time series data to investigate the within-year seasonal dynamics and fluctuations. …”
Get full text

Synergetic monitoring of pressure and temperature stimulations in multisensory electronic skin based on time decoupling effect by Zhiyi Gao, Ye Zhang, Zhenyu Hu, Dongdong Zhang, Shengbin Li, Huiyun Xiao, Ziyin Xiang, Dan Xu, Haifeng Zhang, Yuanzhao Wu, Yiwei Liu, Jie Shang, Runwei Li

“…However, the intuitive and interference‐free reading of multiple sensory signals without involving complex algorithms is a critical challenge. Herein, we propose a flexible multisensory E‐skin by developing a highly homogeneous dispersion of BaTiO3 nanoparticles in polydimethylsiloxane dielectric layer. …”
Get full text

Electroacupuncture Alleviates Neuropathic Pain and Negative Emotion in Mice by Regulating Gut Microbiota by Feng C, Pan H, Zhang Y, Ye Z, Zhou Y, Zou H, Wang K

“…To investigate the impact of gut microbiota on CCI mice, we employed a variety of methods, including various behavioral tests and 16S ribosomal DNA (rDNA) sequencing.Results: The results indicated that EA significantly ameliorated mechanical allodynia and emotional dysfunction induced by CCI in mice. …”
Get full text

Hospital Financial Burden of Surgical Procedures for Periprosthetic Total Hip Arthroplasty Infection by Jesus M. Villa, MD, Tejbir S. Pannu, MD, MS, Robert B. Eysler, BA, Vivek Singh, MD, MPH, Alison K. Klika, MS, Carlos A. Higuera, MD

“…Therefore, when compared to aseptic revisions, we sought to determine (1) Is length of stay (LOS) longer for septic surgeries? …”
Get full text

Use of the SONET Score to Evaluate High Volume Emergency Department Overcrowding: A Prospective Derivation and Validation Study by Hao Wang, Richard D. Robinson, John S. Garrett, Kellie Bunch, Charles A. Huggins, Katherine Watson, Joni Daniels, Brett Banks, James P. D’Etienne, Nestor R. Zenarosa

“…The accuracy and utility of current Emergency Department (ED) crowding estimation tools remain uncertain in EDs with high annual volumes. We aimed at deriving a more accurate tool to evaluate overcrowding in a high volume ED setting and determine the association between ED overcrowding and patient care outcomes. …”
Get full text

Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses by Luiz Paulo Araújo Santos, Leandro do Prado Assunção, Patrícia de Souza Lima, Gabriel Brum Tristão, Matthias Brock, Clayton Luiz Borges, Mirelle Garcia Silva-Bailão, Célia Maria de Almeida Soares, Alexandre Melo Bailão

“…Therefore, fungi require a functional MCC for full virulence and the ability to metabolize propionyl-CoA is related to the virulence traits in Paracoccidioides spp. On this way we sought to characterize the propionate metabolism in Paracoccidioides spp. …”
Get full text

Influence of light intensity, pre-harvest fasting, and storage time on biochemical components in serum and plasma of broilers by Clauber Polese, Lucas Wachholz, Cleison de Souza, Nilton Rohloff Junior, Guilherme Luis Silva Tesser, Rayanne Andrade Nunes, Cinthia Eyng, Jessica Dawn Starkey, Charles William Starkey, Jansller Luiz Genova, Ricardo Vianna Nunes

“…ABSTRACT We determined the impacts of light intensity, fasting, and storage times on total protein (TP), albumin (ALB), globulin (Glb), uric acid (UA), creatinine (Cre), calcium (Ca), phosphorus (P), and alkaline phosphatase (ALP) in serum and plasma of broilers. …”
Get full text

The Antinociceptive and Anti-Inflammatory Activities of Aspidosperma tomentosum (Apocynaceae) by Anansa Bezerra de Aquino, Luiz Henrique Agra Cavalcante-Silva, Carolina Barbosa Brito da Matta, Willians Antônio do Nascimento Epifânio, Pedro Gregório Vieira Aquino, Antônio Euzébio Goulart Santana, Magna Suzana Alexandre-Moreira, João Xavier de Araújo-Júnior

“…We investigated the antinociceptive and anti-inflammatory activities of the crude ethanolic extract (CEE), its fractions, and the flavonoid isorhamnetin from Aspidosperma tomentosum using models of nociception and inflammation in mice. …”
Get full text

THE USE OF ZIRCONIUM CEMENTS IN MEDICINE: PHYSICO-CHEMICAL PROPERTIES AND CLINICAL BENEFITS by Giuroiu Cristian Levente, Clara Haddad, Cristina Albert, Doina Spaiuc, Rusnac Roman, Cezarina Dragomirescu, Alexandru Patrascu, Alina Stefanache

“…In the end, this research will offer a better understanding of how zirconium cements can further improve restorative dentistry and maintain their high demand among dentists across the globe. Material and Methods: We carefully examined appropriate scientific articles to gather the data included in this research. …”
Get full text

Prognostic significance of perioperative circulating CD56bright NK cell and recovery of NK cell activity in patients with colorectal cancer undergoing radical surgery by Jeng-Fu You, Cheng-Chi Lee, Yun-Shien Lee, Yih-Jong Chern, Chun-Kai Liao, Hung-Chih Hsu

“…This study explores the relationship between NK cell/NKA and clinicopathological factors during the perioperative period in patients with CRC. Methods: We prospectively enrolled 45 patients with CRC. …”
Get full text

Cross-agency working when conducting a pragmatic RCT for older victims of crime: our experiences and lessons learned by Marc Serfaty, Jessica Satchell, Gloria K. Laycock, Chris R. Brewin, Marta Buszewicz, Gerard Leavey, Vari M. Drennan, Jonathan Cooke, Anthony Kessel

“…However, as the VIP trial only managed to recruit 131 out of 226 participants, we hope our reflections will help those wishing to conduct research in this population. …”
Get full text

The characteristics of dermatology inpatients seen at the quaternary Inkosi Albert Luthuli Central Hospital in Durban, South Africa, over a 5-year period – 2015 - 2020 by L Mthembu, J T Masuka, K Duze, A Mosam

“…To describe the clinical spectrum and characteristics of inpatient dermatology diseases managed at a quaternary South African (SA) hospital. Methods. We retrospectively reviewed and analysed electronic records of all dermatology inpatients managed by dermatologists from 2015 to 2020 at Inkosi Albert Luthuli Central Hospital (IALCH) in Durban, South Africa. …”
Get full text

Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes by Rebecca Craig-Schapiro, Ge Li, Kevin Chen, Jesus M. Gomez-Salinero, Ryan Nachman, Aleksandra Kopacz, Ryan Schreiner, Xiaojuan Chen, Qiao Zhou, Shahin Rafii, David Redmond

“…Abstract Characterization of the vascular heterogeneity within the pancreas has previously been lacking. Here, we develop strategies to enrich islet-specific endothelial cells (ISECs) and acinar-specific endothelial cells (ASECs) from three human pancreases and corroborate these findings with three published pancreatic datasets. …”
Get full text