Impact of Economic Agglomeration on Carbon Emission Intensity and Its Spatial Spillover Effect: A Case Study of Guangdong Province, China by Qian Xu, Junyi Li, Ziqing Lin, Shuhuang Wu, Ying Yang, Zhixin Lu, Yingjie Xu, Lisi Zha

“…However, the impact of economic development on carbon emission intensity has rarely been considered from the perspective of economic agglomeration, and the relationships and mechanisms between the two remain poorly understood. We analyzed the impact of economic agglomeration on carbon emission intensity and its spatial spillover effect in Guangdong Province, the most economically advantaged province of China, based on a spatial weight matrix generated using geographic proximity, exploratory spatial data analysis (ESDA), and the spatial Durbin model. …”
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Association Between Patient-Reported Pain and Remission or Low Disease Activity in Patients with Rheumatoid Arthritis: Data from RA-BE-REAL Prospective Observational Study by Peter C. Taylor, Walid Fakhouri, Samuel Ogwu, Ewa Haladyj, Inmaculada de la Torre, Bruno Fautrel, Rieke Alten, Peter Nash, Eugen Feist

“…Abstract Introduction We aim to assess the association of patient-reported pain and remission or low disease activity (LDA) at 3 months (M) in patients receiving baricitinib or other treatments in RA-BE-REAL. …”
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Association of ATM Gene Polymorphism with PTC Metastasis in Female Patients by Yulu Gu, Xiaoli Liu, Yaqin Yu, Jieping Shi, Lizhe Ai, Hui Sun, Joseph Sam Kanu, Chong Wang, Yawen Liu

“…The incidence rate of papillary thyroid cancer (PTC) has increased for several decades and is higher in females than males. In this study, we want to investigate whether ATM polymorphisms are associated with gender-specific metastasis of PTC. 358 PTC patients in Northern China, including 109 males and 249 females, were included in our study. …”
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Renal Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Patients with Liver Cirrhosis: A Nationwide Cohort Study by Wei-Fan Hsu, Shi-Hang Yu, Jaw-Town Lin, Jaw-Ching Wu, Ming-Chih Hou, Yi-Hsiang Huang, Chun-Ying Wu, Cheng-Yuan Peng

“…In this nationwide cohort study, we identified 311,361 newly diagnosed cirrhotic patients between January 1997 and December 2013. …”
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Participatory epidemiological approaches for risk assessment of bed bug (Insecta: Hemiptera: Cimicidae) infestation in public hospitals in the city of Faisalabad, Punjab, Pakistan by Arzoo Ashraf, Muhammad Sohail Sajid, Hafiz Muhammad Rizwan, Kashif Hussain, Muhammad Asif Mahmood, Muhammad Imran Arshad, Zain ul Abdin, Shumaila Ashraf, Malcolm K. Jones, Dalia Fouad, Farid S. Ataya

“…Most observations of bed bugs by patients were in their beds (10.42%), with chairs (3.91%) being the second most reported location. However, we found bed bugs from only 17 (4.42%) beds and 5 (1.30%) from chairs. …”
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Spatial and seasonal variability of excess dinitrogen gas in the Baltic Sea by Pratha Sivasamy, Magdalena Diak, Aleksandra Winogradow, Hermann W. Bange, Marta Borecka, Przemysław Makuch, Katarzyna Koziorowska-Makuch, Karol Kuliński, Anna Mackiewicz, Beata Szymczycha

“…To determine the excess of dissolved dinitrogen gas (ΔN2 > 0 indicates the loss of bioavailable dissolved nitrogen) in the water column of the Baltic Proper, we measured N2/Ar ratios below the halocline at 19 stations during different seasons between 2017 and 2021. …”
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Hyperglycemia Does Not Affect Iron Mediated Toxicity of Cultured Endothelial and Renal Tubular Epithelial Cells: Influence of L-Carnosine by Shiqi Zhang, Emmanouil Ntasis, Sarah Kabtni, Jaap van den Born, Gerjan Navis, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

“…Although carnosine has proven its therapeutic efficacy in rodent models of T2DM, little is known about its efficacy to protect cells from iron toxicity. We sought to assess if high glucose (HG) exposure makes cultured human umbilical vein endothelial cells (HUVECs) and renal proximal tubular epithelial cells (PTECs) more susceptible to metal induced toxicity and if this is ameliorated by L-carnosine. …”
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High-Performance Liquid Chromatography Assay for Moxifloxacin in Brain Tissue and Plasma: Validation in a Pharmacokinetic Study in a Murine Model of Cerebral Listeriosis by Renaud Respaud, Solene Grayo, Eric Singlas, Sophie Dubouch, Alban Le Monnier, Marie-Catherine Lott

“…In order to evaluate the pharmacokinetic properties of moxifloxacin in mouse plasma and brain tissue, we developed a high-performance liquid chromatography (HPLC) method. …”
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Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer’s Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis by Shuo Liu, He Chen, Xiao-Dong He, Xiao-Ou Yang

“…By analyzing microarray datasets from the Gene Expression Omnibus (GEO) repository, we identified differentially expressed glucometabolic genes (DEGs) in AD and T2DM cohorts. …”
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Study on Lesion Assessment of Cerebello-Thalamo-Cortical Network in Wilson’s Disease with Diffusion Tensor Imaging by Anqin Wang, Hongli Wu, Chunsheng Xu, Lanfeng Tang, Jaeyoun Lee, Min Wang, Man Jiang, Chuanfu Li, Qi Lu, Chunyun Zhang

“…After registration, patient groups with FA mappings and MD mappings and normal groups were compared with 3dttest and receiver-operating characteristic (ROC) curve analysis, corrected with FDR simulations (p=0.001, α=0.05, cluster size = 326). We found that the degree of FA increased in the bilateral head of the caudate nucleus (HCN), lenticular nucleus (LN), ventral thalamus, substantia nigra (SN), red nucleus (RN), right dentate nucleus (DN), and decreased in the mediodorsal thalamus and extensive white matter. …”
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Rose cultivars for biomonitoring of air quality by Wanjala Sylvia Nafula, László Orlóci, Szilvia Kisvarga, Gábor Boronkay, Béla Tóthmérész, Stewart Ajele, Vanda Éva Abriha-Molnár, Edina Simon

“…The Air Quality Index is based on the concentration of particulate matter, NOx, and SO2. We found that the Air Pollution Tolerance Index values of the selected rose cultivars ranged between 6.8 and 10.5, suggesting that these rose cultivars are sensitive indicators of air pollution. …”
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High-Resolution Geochemical Data Mapping With Swin Transformer-Convolution-Based Multisource Geoscience Data Fusion by Ye Yuan, Shuguang Zhou, Jianhua Bian, Jinlin Wang, Wei Han, Jining Yan

“…Although remote sensing data provides rich surface spectral information and shows a strong correlation with geological features, its accuracy in large-scale geochemical data inversion is insufficient. Therefore, we improve the accuracy and reliability by fusing multisource geoscience data. …”
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Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease by Timo Grimmer, Panagiotis Alexopoulos, Amalia Tsolakidou, Liang-Hao Guo, Gjermund Henriksen, Behrooz H. Yousefi, Hans Förstl, Christian Sorg, Alexander Kurz, Alexander Drzezga, Robert Perneczky

“…It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. We explored associations between CSF BACE1 activity and fibrillar amyloid pathology as measured by carbon-11-labelled Pittsburgh Compound B positron emission tomography ([11C]PIB PET). [11C]PIB and CSF studies were performed in 31 patients with AD. …”
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Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors by G. Lamberti, C. Ceccarelli, N. Brighi, I. Maggio, D. Santini, C. Mosconi, C. Ricci, G. Biasco, D. Campana

“…Archival material should be available for revision according to WHO 2010 neuroendocrine tumor classification and for p-mTOR, SSTR2A, and IGF-1R immunostaining, calculating a quantitative score (QS). We evaluated clinical, pathological, and immunohistochemistry features for association with the presence of advanced disease at diagnosis and disease relapse in patients who have undergone radical surgery. …”
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Body Mass Index Trajectories during 6–18 Years Old and the Risk of Hypertension in Young Adult: A Longitudinal Study in Chinese Population by Haoyue Teng, Jia Hu, Wenxin Ge, Qiling Dai, Ji Liu, Chengqi Xiao, Jieyun Yin, Xiaoyan Zhu

“…Overweight/obesity in childhood is suggested to increase the risk of hypertension later in life. We aimed to assess whether and how body mass index (BMI) trajectories during 6–18 years of age are associated with hypertension in young adulthood (18–37 years) in the Chinese population. …”
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Electrocardiographic Changes in Pregnant Patients With Congenital Heart Disease by Maria A. Pabon, Amrit Misra, Kimberlee Gauvreau, Madeline E. Duncan, Ava Conklin, Katherine E. Economy, Fred M. Wu, Thomas Tadros, Anne Marie Valente, For the STORCC Investigators

“…However, in pregnant patients with congenital heart disease (CHD), EKG changes during gestation have not been explored. Methods We performed a retrospective study of pregnant patients with CHD enrolled in the STORCC initiative. …”
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Glaucomatous Visual Field Defect Severity and the Prevalence of Motor Vehicle Collisions in Japanese: A Hospital/Clinic-Based Cross-Sectional Study by Takeshi Ono, Kenya Yuki, Ryo Asaoka, Keisuke Kouyama, Takayuki Abe, Sachiko Tanabe, Kazumi Fukagawa, Miki Uchino, Masaru Shimoyama, Yoko Ozawa, Naoki Ozeki, Daisuke Shiba, Kazuo Tsubota

“…Subjects with POAG were classified as having mild, moderate, or severe visual field defect. We evaluated associations between the severity of POAG and the prevalence of MVCs by logistic regression models. …”
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Clinical Significance of Peripheral Blood T Lymphocyte Subsets in Helicobacter pylori-Infected Patients by Yuka Satoh, Hatsue Ogawara, Osamu Kawamura, Motoyasu Kusano, Hirokazu Murakami

“…In order to clarify the immunological changes induced by this infection, we determined the percentage and, as indicated, ratios of the following cells in peripheral blood of 45 H. pylori-infected patients and 21 control subjects: CD4+ T cell, CD8+ T cells, T helper 1 cells (Th1), T helper 2 cells (Th2), CD4+CD25+ T cells, Foxp3+ regulatory T cells (Tregs), CD4/CD8 ratio, and Th1/Th2 ratio. …”
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Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children: a prospective cohort study by Peter Aaby, Per Kallestrup, Christine Stabell Benn, Sanne M Thysen, Ane Fisker, Victor Francisco Gomes, Frauke Rudolf, Christian Wejse, Adam Roth

“…Children residing in the same house as a TB case were classified as TB-exposed from 3 months prior to case registration to the end of follow-up.Methods Using Cox-proportional hazards models with age as underlying time scale, we compared mortality of children with and without neonatal BCG between October 2003 and September 2017.Main outcome measure HR for neonatal BCG compared with no neonatal BCG by TB-exposure status.Results Among the 39 421 children who entered the analyses, 3022 (8%) had observation time as TB-exposed. …”
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Gastroprotective Effects of Aqueous Extracts of Broccoli Stems on Acute Injury in Rats: A Comprehensive Evaluation of Gastric Function and Inflammatory Responses by Jihye Choi, Yuseong Jang, Hyeon-Gi Paik, Melissa Hyun-Joo Ha, Jungkee Kwon

“…<i>Background and Objectives</i>: Acute gastric injury is a prevalent gastrointestinal disorder characterized by inflammation and damage to the stomach lining. In this study, we investigated the therapeutic potential effects of broccoli stem extract (BSE) against acute gastritis in a rat model. …”
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