Performance evaluation of the Qiagen BK virus ASR on the NeuMoDx system by Amorce Lima, Luciano Soares, Caroline Simmons, Laura Rowe, Dominic Uy, Deanna Becker, Suzane Silbert

“…BKV quantitation by PCR is crucial in diagnostic and therapeutic management of transplant patients infected with BKV. We evaluated the performance of the Qiagen BKV ASR for the quantification of BKV on the NeuMoDx™ 96 System and compared the results to our standard of care (SOC) test, the Diasorin BKV ASR on the Liaison® MDX. …”
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Machine learning analysis of cervical balance in early-onset scoliosis post-growing rod surgery: a case-control study by Bo Han, Junrui Jonathan Hai, Aixing Pan, Yingjie Wang, Yong Hai

“…Abstract We aimed to analyze the cervical sagittal alignment change following the growing rod treatment in early-onset scoliosis (EOS) and identify the risk factors of sagittal cervical imbalance after growing-rod surgery of machine learning. …”
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Aberrant Expression of MicroRNA-15a and MicroRNA-16 Synergistically Associates with Tumor Progression and Prognosis in Patients with Colorectal Cancer by Guangfa Xiao, Huihuan Tang, Wei Wei, Jian Li, Liandong Ji, Jie Ge

“…The aim of this study was to reveal the associations of microRNA miR-15a and miR-16 dysregulation with clinicopathological characteristics and prognosis in patients with colorectal cancer. As a result, we found that miR-15a and miR-16 expression, detected by quantitative real time-PCR, were both significantly downregulated in colorectal cancer tissues compared with adjacent colorectal mucosa (both P<0.001). …”
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Prebreeding research of near-isogenic lines of spring bread wheat with a combination of translocations from Agropyron elongatum (Host.) Р.В. and Aegilops ventricosa Tausch. by S. N. Sibikeev, A. E. Druzhin

“…They reveal effects of translocations on the adaptive properties of plants, performance indices, yield, and the quality of the final product. For this purpose, we studied the L653 and L654 near-isogenic lines of spring bread wheat cultivar Dobrynya, resistant to leaf rust and carrying the combination of translocations 7DS • 7 DL-7Ae#1L + 2AL • 2AS-2MV#1, which host genes Lr19/Sr25 from Agropyron elongatum (Host.) …”
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A Novel Spontaneous Mutation of the SOX10 Gene Associated with Waardenburg Syndrome Type II by Sen Chen, Yuan Jin, Le Xie, Wen Xie, Kai Xu, Yue Qiu, Xue Bai, Hui-Min Zhang, Xiao-Zhou Liu, Xiao-Hui Wang, Wei-Jia Kong, Yu Sun

“…Among them, SOX10 mutation is responsible for approximately 15% of type II WS or 50% of type IV WS. We report the case of a proband in a Chinese family who was diagnosed with WS type II. …”
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Prevalence and Risk Factors of Work-Related Upper Extremity Disorders among University Teaching Staff in Ethiopia, 2021: An Institution-Based Cross-Sectional Study by Amensisa Hailu Tesfaye, Tesfaye Hambisa Mekonnen, Mekuriaw Alemayehu, Giziew Abere

“…Materials and Methods. We conducted a cross-sectional study design from March to April 2021. …”
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Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis by Xiaoyu Huang, Zhouao Zhang, Zhouyi Wang, Tiancheng Luo, Mingjin Yang, Xinyan Guo, Xue Du, Tianyu Ma, Yong Zhang

“…However, targeted B-cell therapy such as rituximab may result in long-term peripheral B cell clearance and allow for the survival of plasma cells, contributing to frequent infections and relapses. Therefore, we aimed to identify potential novel therapeutic targets that preserve part of B cell function while inhibiting antibody-secreting cells (ASCs). …”
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A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula by Nicolás Vidal-Vázquez, Ismael Hernández-Núñez, Pablo Carballo-Pacoret, Sarah Salisbury, Paula R. Villamayor, Francisca Hervas-Sotomayor, Xuefei Yuan, Francesco Lamanna, Céline Schneider, Julia Schmidt, Sylvie Mazan, Henrik Kaessmann, Fátima Adrio, Diego Robledo, Antón Barreiro-Iglesias, Eva Candal

“…However, similar data in cartilaginous fishes, the sister group to all other extant jawed vertebrates, are still lacking. Here, we present a single-nucleus RNA sequencing atlas of the postnatal retina of the catshark Scyliorhinus canicula, consisting of the expression profiles for 17,438 individual cells from three female, juvenile catshark specimens. …”
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Spatiotemporal Assessment of Temperature Data Products for the Detection of Warming Trends and Abrupt Transitions over the Largest Irrigated Area of Pakistan by Zain Nawaz, Xin Li, Yingying Chen, Xufeng Wang, Kun Zhang, Naima Nawaz, Yanlong Guo, Akynbekkyzy Meerzhan

“…Gridded data products (GDPs) offer an opportunity to estimate and monitor temperature indices at a range of spatiotemporal resolutions; however, their reliability must be quantified by spatiotemporal comparison against in situ records. Here, we present spatial and temporal assessments of temperature indices (Tmax, Tmin, Tmean, and DTR) products against the reference data during the period of 1979–2015 over Punjab Province, Pakistan. …”
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Acute portal vein thrombosis in an isolated, blunt, minor liver injury near the porta hepatis by Onchuda Wongweerakit, Osaree Akaraborworn, Burapat Sangthong, Komet Thongkhao

“…Moreover, acute asymptomatic PVT is difficult to diagnose. We present a young trauma patient with isolated minor liver injury associated with acute PVT. …”
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Novel Compound Heterozygous BBS2 and Homozygous MKKS Variants Detected in Chinese Families with Bardet–Biedl Syndrome by Li Huang, Limei Sun, Zhirong Wang, Songshan Li, Chonglin Chen, Xiaoling Luo, Xiaoyan Ding

“…Bardet–Biedl syndrome (BBS) is a rare multisystem developmental disorder. In this study, we report the genetic causes and clinical manifestations in two Chinese families with BBS. …”
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Diagnostic Value of High-Sensitivity Troponin T for Subclinical Left Ventricular Systolic Dysfunction in Patients with Sepsis by Pham Dang Hai, Nguyen Thanh Binh, Nguyen Hong Tot, Ha Manh Hung, Le Thi Viet Hoa, Nguyen Viet Quang Hien, Pham Nguyen Son

“…However, there are limited data regarding the association between hs-cTnT level and left ventricular systolic dysfunction based on STE in septic patients. We performed this prospective study to evaluate the diagnostic value of hs-cTnT level for subclinical left ventricular systolic dysfunction measured by STE in septic patients according to the sepsis-3 definition. …”
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The impact of weight change on suicide mortality: a nationwide population-based cohort study of 2 million Koreans by Kyuho Kim, Jin-Hyung Jung, Yoo Hyun Um, Yu-Bae Ahn, Seung-Hyun Ko, Kyungdo Han, Jae-Seung Yun

“…However, its association with suicide mortality remains undetermined. In this study, we investigated the association between weight change and suicide mortality using a large-scale, population-based cohort from the Korean National Health Insurance Service database. …”
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Medicinal plants used to treat human ailments in Wadla District, Northern Ethiopia: An ethnobotanical approach by Sara Yosef, Ermias Lulekal, Asfaw Debela, Muhidin Tahir

“…Semistructured interviews, group discussions, guided field walks, and field observations were used to collect the data. We analysed the data using descriptive statistics, including direct matrix rankings, preference rankings, informant consensus factors, and fidelity levels. …”
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BTS1-knockout Saccharomyces cerevisiae with broad-spectrum antimicrobial activity through lactic acid accumulation by Liu Cong, Yuan Zhou, Yu Zhang, Shanshan Mao, Chaoqun Chen, Liying Wang, Xiao Li, Zuo Zhang, Zuobin Zhu, Ying Li

“…Probiotics have emerged as a promising approach to combating pathogenic bacterial infections. In this study, we investigated the antibacterial activity of BTS1-knockout (BTS1-KO) Saccharomyces cerevisiae. …”
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Desalted duck egg white nanogels as Pickering stabilizers for food-grade oil-in-water emulsion by Jingyun Zhao, Xiaohan Guo, Ze Chen, Yalei Dai, Hongshan Liang, Qianchun Deng, Shugang Li, Bin Zhou

“…Achieving the reuse of traditional egg by-products, salted duck egg whites (SEW), is an urgent problem to be solved. In this current work, we constructed a heat-induced gel-assisted desalination method for SEW. …”
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Expression of LINC00847 in Peripheral Blood Mononuclear Cells of Children with Asthma and Its Prediction between Asthma Exacerbation and Remission by Jiaying Hu, Zhike Wang, Suzhen Han, Kai Chen

“…To know more about the relationships between lncRNAs and asthma, we sought to the role of LINC00847 in peripheral blood mononuclear cells (PBMCs) of children with asthma exacerbation or asthma remission. …”
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Is the treatment of ankle osteoarthritis changing over time in Italy? Analysis of temporal trends for fusion and arthroplasty in a population-based study from 2001 to 2022 on the N... by Adriano Cuccu, Elena Manuela Samaila, Enrico Ciminello, Umberto Alfieri Montrasio, Fabrizio Cortese, Stefania Ceccarelli, Tiziana Falcone, Marina Torre

“…Furthermore, as a secondary aim, we compared these trends with those of ankle fusions. …”
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Modified Trochanteric Flip Osteotomy in Varus Intertrochanteric Osteotomy for Treatment of Legg–Calvé–Perthes Disease by Andrea Laufer, Carina Antfang, Georg Gosheger, Adrien Frommer, Gregor Toporowski, Henning Tretow, Robert Roedl, Bjoern Vogt

“…This study aimed to evaluate the efficacy of combining proximal femoral varus osteotomy (PFVO) with a modified trochanteric flip osteotomy to address biomechanical consequences and improve hip abductor muscle strength. <b>Methods</b>: We present a modified approach combining PFVO with a trochanteric flip osteotomy. …”
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Value of C-Reactive Protein as a Risk Factor for Acute Coronary Syndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile by Magdalena Krintus, Marek Kozinski, Anna Stefanska, Marcin Sawicki, Karolina Obonska, Tomasz Fabiszak, Jacek Kubica, Grazyna Sypniewska

“…Only CRP significantly increased the probability of ACS development (adjusted odds ratio for a 1 mg/L increase 1.90; 95% confidence interval [CI] 1.34–2.89) and explained 90% of the variation for ACS development. Similarly, we demonstrated the highest diagnostic accuracy for CRP among all investigated markers (area under the curve 0.80; 95% CI 0.75–0.85). …”
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