DeepExtremeCubes: Earth system spatio-temporal data for assessing compound heatwave and drought impacts by Chaonan Ji, Tonio Fincke, Vitus Benson, Gustau Camps-Valls, Miguel-Ángel Fernández-Torres, Fabian Gans, Guido Kraemer, Francesco Martinuzzi, David Montero, Karin Mora, Oscar J. Pellicer-Valero, Claire Robin, Maximilian Söchting, Mélanie Weynants, Miguel D. Mahecha

“…Despite recent progress in deep learning to ecosystem monitoring, there is a need for datasets specifically designed to analyse compound heatwave and drought extreme impact. Here, we introduce the DeepExtremeCubes database, tailored to map around these extremes, focusing on persistent natural vegetation. …”
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Three-Dimensional Digital Documentation for the Conservation of the Prambanan Temple Cluster Using Guided Multi-Sensor Techniques by Anindya Sricandra Prasidya, Irwan Gumilar, Irwan Meilano, Ikaputra Ikaputra, Rochmad Muryamto, Erlyna Nour Arrofiqoh

“…Furthermore, visually, every point cloud model from each sensor successfully complemented each other. Therefore, we can conclude that our approach is promising for complex heritage documentation. …”
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Mass gatherings in Italy: a study from the 2015 Milan Expo by Pietro Marino, Enzo Albergoni, Aida Andreassi, Gianluca Chiodini, Lucia Colombi, Cristina Corbetta, Gabriella Nucera, Marco Salmoiraghi, Alberto Zoli

“…The Pre-Hospital Emergency Company (AREU) of Lombardy Region (Milan-Italy) was involved in planning and managing the emergency rescue response inside the Expo 2015 area in Milan. In this paper, we review the AREU medical and public health response for the 2015 Milan Expo. …”
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Definition, criteria, and core concepts of guidelines for the management of obesity disease in Japan by Wataru Ogawa, Yushi Hirota, Shigeru Miyazaki, Tadashi Nakamura, Yoshihiro Ogawa, Iichiro Shimomura, Toshimasa Yamauchi, Koutaro Yokote, on behalf of the Creation Committee for Guidelines for the Management of Obesity Disease 2022 by Japan Society for the Study of Obesity (JASSO)

“…To identify those who might benefit from weight reduction within a large population of obese individuals, Japan Society for the Study of Obesity (JASSO) advocated the concept of “obesity disease.” Here we summarize the definition, criteria, and core concepts for the management of obesity disease based on JASSO’s latest guideline. …”
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Poor Control of Plasma Triglycerides Is Associated with Early Decline of Estimated Glomerular Filtration Rates in New-Onset Type 2 Diabetes in China: Results from a 3-Year Follow-U... by Chuan Wang, Lingshu Wang, Kai Liang, Fei Yan, Xinguo Hou, Fuqiang Liu, Li Chen

“…This study aims to explore the impact of long-term lipid control on renal outcome in new-onset type 2 diabetes mellitus (T2DM). Methods. We conducted a 3-year follow-up study, involving 283 subjects with new-onset T2DM, and observed the effect of baseline and follow-up metabolic abnormalities, especially dyslipidemia, on the early damage of kidney function using multiple logistic regression analysis. …”
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Amorphous silica reduces N2O emissions from arable land at the field plot scale by Mathias Hoffmann, Oscar Rodrigo Monzon Diaz, Isabel Zentgraf, Wael Al-Hamwi, Maren Dubbert, Mathias Stein, Maire Holz, Jörg Schaller, Jörg Schaller

“…Both factors are known to directly and indirectly affect N2O emissions from agroecosystems.MethodsIn this study we conducted a field plot trial on arable soil depleted in ASi and fertilized this soil to its pre-agricultural ASi level.ResultsOur data clearly shows that increasing soil ASi to a pre-agricultural level decreased seasonal N2O emissions by ∼30%.DiscussionThis reduction of N2O emissions due to ASi might be of global relevance as agricultural practice has reduced the ASi content in agricultural soils. …”
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Diagnostic cholangioscopy for surgical planning of extrahepatic cholangiocarcinoma by Min Je Sung, Suk Pyo Shin, Chang-Il Kwon, Incheon Kang, Sung Hwan Lee, Seok Jeong Yang, Beodeul Kang, Hong Jae Chon, Gwangil Kim, Chansik An, Kwang Hyun Ko

“…The aim of this study was to evaluate the role of SOC in surgical planning for extrahepatic CCC. We reviewed the consecutive data of patients who received nab-paclitaxel plus gemcitabine-cisplatin for the management of extrahepatic CCC and underwent preoperative evaluations between June 2020 and August 2022. …”
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Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience by Meltem CAGLAR OSKAYLI, Furkan ERSOY, Neslihan GULCIN, Ahmet PIRIM, Seyhmus Kerem OZEL, Seyma OZKANLI, Cigdem ULUKAYA DURAKBASA

“…Objective: Gastrointestinal duplications are rare congenital anomalies. Herein, we present a single institutional experience in pediatric gastrointestinal tract duplications. …”
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Effects of Novaluron Exposure on the Oviposition and Expression of Ovarian Development Related Genes in Silkworm, <i>Bombyx mori</i> (Lepidoptera: Bombycidae) by Meng-Jiao Wang, En-Xi Chen, Yi-Lin Ji, Yi-Xuan Qian, Yu-Ming Zhang, Lin Zhu, Guo-Dong Zhao, He-Ying Qian

“…In addition, the transcription levels of genes related to ovary development (<i>Vg</i>, <i>Ovo</i>, <i>Otu</i>, <i>Sxl-S</i> and <i>Sxl-L</i>) and hormone regulation (<i>EcR</i> and <i>JHBP</i>2) showed varying degrees of downregulation at 24 h, 48 h, and 72 h after novaluron treatment (<i>p</i> ≤ 0.05). Therefore, we speculated that novaluron can affect the energy metabolism, ovary development, and egg formation of silkworms, thus leading to reproductive disorders of silkworms after novaluron exposure.…”
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Roadmap for Designing Donor-<inline-formula><math display="inline"><semantics><mrow><mi mathvariant="bold-sans-serif">π</mi></mrow></semantics></math></inline-formula>-Acceptor Flu... by Guliz Ersoy, Maged Henary

“…D-<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="sans-serif">π</mi></mrow></semantics></math></inline-formula>-A fluorophores with carboxylic acid and cyano groups are preferred in photovoltaic applications, and fluorophores with large surface area are used for two photon absorbing applications. Herein, we report the synthesis, optical properties, and applications of various D-<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="sans-serif">π</mi></mrow></semantics></math></inline-formula>-A fluorophores in UV-vis and NIR region.…”
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Efficacy of Acupuncture Treatment for Postprandial Distress Syndrome: A Systematic Review and Meta-Analysis by Jihang Du, Yinhao Feng, Qiang Yuan, Haiping Gong, Jie An, Liu Wu, Qian Dai, Bojun Xu, Haozhong Wang, Jian Luo

“…Stata 15.0 software was used for meta-analysis. Result. We initially identified 63 studies, of which five (1253 participants) were eventually included in our analysis. …”
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Conservation value and ecosystem service provision of Nothofagus antarctica forests based on phenocluster categories by Guillermo J. Martínez Pastur, Julián Rodríguez-Souilla, Yamina M. Rosas, Natalia Politi, Luis Rivera, Eduarda M. O. Silveira, Ashley M. Olah, Anna M. Pidgeon, María V. Lencinas, Pablo L. Peri

“…The objective was to compare the conservation value (capacity to support more native biodiversity) and provision of ecosystem services (ES) in different phenocluster categories of Nothofagus antarctica forests in Tierra del Fuego (Argentina). We used available models (ES, potential biodiversity) and ground-truth data of 145 stands, comparing phenocluster values using uni- and multivariate analyses. …”
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Chemical Diversity of UK-Grown Tea Explored Using Metabolomics and Machine Learning by Amanda J. Lloyd, Alina Warren-Walker, Jasen Finch, Jo Harper, Kathryn Bennet, Alison Watson, Laura Lyons, Pilar Martinez Martin, Thomas Wilson, Manfred Beckmann

“…The intraclass variability in leaf composition was similar between the varieties. We explored the metabolic changes over the day in one variant (<i>Camellia assamica</i> Masters), yielding a model with a significant R² value of 0.617 (<i>p</i> < 0.01, 3000 permutations). …”
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MORPHOFUNCTIONAL CHARACTERISTICS OF LEAVES AND FRUITS IN MALOIDEAE (ROSACEAE): b. THE ROLE OF SURFACE TISSUES IN THE FORMATION OF RESISTANCE TO FUNGAL DISEASES by T. Kh. Kumachova, O. O. Beloshapkina, A. S. Voronkov, A. S. Ryabchenko

“…It is particularly informative in the case of organisms with complex surface micromorphology and for studying the biodiversity of pathogens. However, in this work we combined the methods of light, electron (SEM, TEM) and confocal microscopy. …”
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TO THE BASICS OF MODERN POLITICAL ANTHROPOLOGY: FREEDOM AND JUSTICE IN THE SOCIAL CONTRACT THEORY OF T. HOBBES by L. A. Sytnichenko, D. V. Usov

“…For an in-depth study of the philosophical and anthropological aspects of Hobbes’s contractualism, we used the historical-comparative and contextualization method, as well as the works of leading native and foreign researchers of Hobbes, who uphold the provisions on the organic affiliation of fundamental socio-philosophical and philosophical-anthropological questions about the nature of man, the relation of coercion, freedom and justice with the discourse of social contract. …”
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Psychometric Testing of the CHAMPS Questionnaire in French Canadians with COPD by Susanne Mak, Jean Bourbeau, Nancy E. Mayo, Sharon Wood-Dauphinee, Judith E. Soicher

“…In a previous article, we reported on the cross-cultural adaptation of the Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire to produce a Canadian French version. …”
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Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer by Shaopeng Zhang, Ximo Xu, Kundong Zhang, Changzheng Lei, Yitian Xu, Pengshan Zhang, Yuan Zhang, Haitao Gu, Chen Huang, Zhengjun Qiu

“…M2d is characterized by elevated secretion of IL-10 and VEGF-A, which diminish CD8+T cells cytotoxicity and promote tumor neoangiogenesis simultaneously. Additionally, we identify 2,5’-oligoadenylate synthase 3 (OAS3) as an essential regulator of M2d polarization, upregulated by PCs via lactate/METTL3/OAS3 axis. …”
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Disrupting effects of neonicotinoids and their interaction with metals on thyroid hormone, an evidence of children in a rural area, South China by Ling-Chuan Guo, Pan Zhu, Chunyan Gui, Jing Deng, Yanhong Gao, Chaoyang Long, Han Zhang, Zhanlu Lv, Shengbing Yu

“…To fill this knowledge gap, we conducted a cross-sectional study on children of a rural area in South China (n = 88), and analyzed urinary ten neonicotinoids (including metabolites), serum TH, thyroxine-binding globulin (TBG), and thyroid stimulating hormone (TSH) levels. …”
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Application of an integrated behaviour-change model on grandparental adherence towards childhood domestic injury prevention in Hong Kong: a longitudinal study by Martin S Hagger, Patrick Ip, Derwin King Chung Chan, Roni Man Ying Chiu, Catherine M Capio, Patrick S H Yung, Agnes Y K Lai

“…The risks of domestic injury can be reduced through proper implementation of injury preventive measures. In this study, we investigated the motivational and belief processes underlying childhood domestic injury prevention in grandparent caregivers based on the integrated model of self-determination theory and theory of planned behaviour.Method Grandparents (n=299, mean age=62.61 years, SD=5.91, men=20.07%) of 0–2-year-old infants and toddlers self-reported their perceived psychological need support, autonomous motivation, perceived behavioural control (PBC), subjective norms, attitude, intention and adherence with regard to domestic injury prevention for their children at two time points (T1: baseline, T2: 4-month follow-up).Results/outcomes Data were analysed with structural equation modelling, and the proposed model yielded an acceptable fit with the data: χ2=905.09 (df=531), Comparative Fit Index=0.94, Tucker-Lewis Index=0.93, root mean square error of approximation=0.05 and standardised root mean square residual=0.078. …”
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Effectively alleviate rheumatoid arthritis via maintaining redox balance, inducing macrophage repolarization and restoring homeostasis of fibroblast-like synoviocytes by metformin-... by Rui Zhang, Xingyu Lin, Rongjie Lin, Zhenbin Chen, Chenfang Miao, Yao Wang, Xiaoqin Deng, Jianlong Lin, Shishui Lin, Shaohuang Weng, Min Chen

“…Hence, synergistic combination of ROS scavenging, macrophage polarization from pro-inflammatory M1 phenotype towards M2 anti-inflammatory phenotype, and restoring homeostasis of FLSs will provide a promising therapeutic strategy for RA. In this study, we successfully synthesized metformin-derived carbon dots (MCDs), and investigated the antirheumatic effect in vivo and in vitro. …”
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