Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…Here it is demonstrated that dynamic light scattering (DLS) is sensitive and effective at measuring variation in lipoprotein size distributions following oxidative damage caused by peroxidation and nitration—two common physiological processes that play dual roles in both normal and pathogenic states. We establish the utility of DLS in detecting subtle variations in lipoprotein size, including potential aggregation and fission events resulting from chemical modifications. …”
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Antitumor effects of natural killer cells derived from gene-engineered human-induced pluripotent stem cells on hepatocellular carcinoma by Mayuna Nakamura, Yuka Tanaka, Keishi Hakoda, Masahiro Ohira, Tsuyoshi Kobayashi, Kenji Kurachi, Kouichi Tamura, Hideki Ohdan

“…The eNK cells (HLCN061, developed by HEALIOS K.K.) are human iPSC-derived NK cells differentiated from clinical-grade iPSCs in which IL-15, CCR2B, CCL19, CD16a, and NKG2D have been introduced. In this study, we aimed to evaluate the potential of eNK cell therapy for HCC treatment. …”
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Validation of In-field Calibration for Low-Cost Sensors Measuring Ambient Particulate Matter in Kolkata, India by Siddharth Nobell, Arnab Majumdar, Shovon Mukherjee, Sukumar Chakraborty, Sanjoy Chatterjee, Soumitra Bose, Anindita Dutta, Sandhya Sethuraman, Daniel M. Westervelt, Shairik Sengupta, Rakhi Basu, V. Faye McNeill

“…Abstract Low-cost sensors (LCS) provide opportunities for neighborhood-level air pollution data collection, yet significant knowledge gaps remain regarding the accurate application and interpretation of LCS. In this study, we present an in-field calibration of a network of 20 low-cost ambient particulate matter sensors (LCS) in greater Kolkata, India, operating between October 2018–April 2019. …”
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Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study by Seyed Moayed Alavian, Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena HL Borba, Asma Sabermahani, Behzad Hajarizadeh

“…A 1-year cycle length was used to calculate the cumulative cost and effectiveness over a lifetime time horizon. We calculated quality-adjusted life years (QALYs), and incremental cost-effectiveness ratio (ICER) using a health system perspective. …”
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Optimising subsurface integrity and surface quality in mild steel turning: A multi-objective approach to tool wear and machining parameters by Muhammad Imran, Suo Shuangfu, Bai Yuzhu, Wang Yuming, Naveed Raheel

“…This study investigates the impact of machining parameters and tool dynamics on mild steel degradation of surface quality and subsurface, including heat effects, deformation, and microstructural changes that lead to microcracks and work hardening. Firstly, we examined the individual impacts of cutting velocity (Vc), feeding rate (f), and depth of cut (ap) on surface roughness and surface topography. …”
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Fostering unsustainability? An analysis of 4-year-olds' dietary impacts in Sweden by Maria Jacobsen, Lotta Moraeus, Emma Patterson, Anna Karin Lindroos, Mattias Eriksson, Elin Röös

“…It employed the Sustainability Assessment of Foods And Diets tool to quantify these impacts against per capita 1000 kcal planetary boundaries and variations in dietary impacts based on factors such as gender, municipal area, parental education level, and consumption setting (home or preschool). We found that the mean dietary impacts fell within or exceeded the uncertainty zone per capita planetary boundaries for five out of six indicators, with only blue water use remaining within the ‘safe space’; notably, zero children had eaten below the uncertainty levels for all indicators. …”
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The ANGPTL8 rs2278426 (C/T) Polymorphism Is Associated with Prediabetes and Type 2 Diabetes in a Han Chinese Population in Hebei Province by Guangsen Hou, Yong Tang, Luping Ren, Yunpeng Guan, Xiaoyu Hou, Guangyao Song

“…Our aim was to investigate the association between the genetics of the angiopoietin protein-like 8 (ANGPTL8) rs2278426 (C/T) polymorphism with prediabetes (pre-DM) and type 2 diabetes (T2DM) in a Han Chinese population in Hebei Province, China. Methods. We enrolled 1,460 participants into this case-control study: healthy controls, n = 524; pre-DM, n = 460; and T2DM: n = 460. …”
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Association between medication adherence and disease outcomes in patients with hepatitis B-related cirrhosis: a population-based case–control study by Vivian Chia-Rong Hsieh, Kuo-Yu Fu, Meng-Lun Hsieh, Jou-An Chen

“…After accounting for confounding variables, we find that the likelihood of complicated cirrhosis is significantly lower in more adherent patients and the benefit increases with more persistent adherence (log 1-year MPR OR: 0.75, 95% CI: 0.73 to 0.77). …”
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Decoding the chicken gastrointestinal microbiome by PB. Burrows, F. Godoy-Santos, K. Lawther, A. Richmond, N. Corcionivoschi, SA. Huws

“…Consequently, in this study we characterised the overall and common ‘core’ chicken microbiota associated with the gastrointestinal tract (GIT), whilst assessing the effects of GIT site, bird breed, age and geographical location on the GIT resident microbes using metataxonomic data compiled from studies completed across the world. …”
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Phosphorus Fertilization and Chemical Root Pruning: Effects on Root Traits During the Nursery Stage in Two Mediterranean Species from Central Chile by Fiorella Calderón-Ureña, Carolina Álvarez-Maldini, Manuel Acevedo, Manuel E. Sánchez-Olate, R. Kasten Dumroese, Antay Sierra-Olea, Juan F. Ovalle, Edwin Esquivel-Segura

“…Accordingly, nursery practices like phosphorous (P) fertilization and root pruning have been shown to modify root architecture; however, their combined benefits require further investigation in Mediterranean species. We evaluated the effect of applied P concentrations (0, 15, 60, and 120 mg L⁻¹ P) with or without chemical (copper) root pruning (WCu, WoCu, respectively) in <i>Aristotelia chilensis</i> and <i>Quillaja saponaria</i> on morpho-physiological and root architecture traits. …”
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Antenatal care and breastfeeding practices in Sub-Saharan Africa: an analysis of demographic and health surveys by Bolanle Olapeju, Michael Bride, Mariam Wamala, Deborah Atobrah, Elizabeth H. Lee, Zoé M. Hendrickson

“…This study investigates i) trends in breastfeeding practices across sub-Saharan Africa following the rollout of the revised WHO 2016 ANC policy and ii) the relationship between ANC uptake and exclusive or early breastfeeding. Methods We performed a secondary analysis of Demographic and Health Survey data from 19 countries, from 2018-2023. …”
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Controllable tip exposure of ultramicroelectrodes coated by diamond-like carbon via direct microplasma jet for enhanced stability and fidelity in single-cell recording by Zhiyuan Du, Qingda Xu, Ye Xi, Mengfei Xu, Jiawei Cao, Longchun Wang, Xiuyan Li, Xiaolin Wang, Qingkun Liu, Zude Lin, Bin Yang, Jingquan Liu

“…To address this issue, we chose a dense and electrochemically stable diamond-like carbon (DLC) film as the UME protection coating and developed a method to precisely control the exposed degree of the functional structure by directly fixed-point processing of the UME tip by the strong site-selectivity and good controllability of the atmospheric microplasma jet. …”
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Apigenin, a natural flavonoid, promotes autophagy and ferroptosis in human endometrial carcinoma Ishikawa cells in vitro and in vivo by Yancui Liang, Qian Zhong, Runhui Ma, Zhijing Ni, Kiran Thakur, Jianguo Zhang, Zhaojun Wei

“…There are few reports on the mechanism of apigenin on autophagy and ferroptosis of endometrial cancer Ishikawa cells. We found that iron accumulation, lipid peroxidation, glutathione consumption, p62, HMOX1, and ferritin were increased, while, solute carrier family 7 member 11 and glutathione peroxidase 4 were decreased. …”
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Analysis of Bulk Queueing Model with Load Balancing and Vacation by Subramani Palani Niranjan, Suthanthiraraj Devi Latha, Sorin Vlase, Maria Luminita Scutaru

“…Load balancing is one such data architecture used to efficiently distribute network traffic to the server. In this paper, we incorporated the load-balancing technique used in cloud computing with power business intelligence (BI) and cloud load based on the queueing theoretic approach. …”
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The CuePed Trial: How Does Environmental Complexity Impact Cue Effectiveness? A Comparison of Tonic and Phasic Visual Cueing in Simple and Complex Environments in a Parkinson’s Dis... by Rodney Marsh, Michael H. Cole, Nadeeka N. W. Dissanayaka, Tiffany R. Au, Sandra Clewett, John D. O’Sullivan, Peter A. Silburn

“…It is not known whether these devices offer benefit over simple (tonic) cueing devices. Methods. We assembled 20 participants with PD and FoG and familiarized them with a belt-worn, laser-light cueing device (Agilitas™). …”
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Genetic diversity of potato varieties bred in Russia and near-abroad countries based on polymorphism of SSR-loci and markers associated with resistance R-genes by O. Y. Antonova, N. A. Shvachko, L. Y. Novikova, O. Y. Shuvalov, L. I. Kostina, N. S. Klimenko, A. R. Shuvalova, T. A. Gavrilenko

“…Application of 14 highly polymorphic nuclear microsatellites (SSR) enabled the complete discrimination of all 113 varieties. Additionally, we have studied these varieties for the distribution of 8 DNA markers associated with three R-genes involved in the control of resistance to two quarantine objects: the potato wart Synchytrium endobioticum and golden potato cyst nematode Globodera rostochiensis, which occur locally in some regions of the Russian Federation. …”
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LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure by Yongjuan Wang, Xiaoli Xie, Hongqun Liu, Huimin Liu, Huiqing Jiang

“…Besides, neutralization of CCL20 blocked the effects of LR12, thus inhibited the proliferation of LO2 cells in vitro, aggregated the liver inflammation, and restrained hepatocyte regeneration in ALF mice in vivo. Furthermore, we also found that LR12 activated the p38 mitogen-activated protein kinase (MAPK) pathway in hepatocytes through promoting the secretion of CCL20 from macrophages. …”
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Analysis of Nucleotide Variations in Genes of Iron Management in Patients of Parkinson's Disease and Other Movement Disorders by Emanuela Castiglioni, Dario Finazzi, Stefano Goldwurm, Gianni Pezzoli, Gianluca Forni, Domenico Girelli, Federica Maccarinelli, Maura Poli, Maurizio Ferrari, Laura Cremonesi, Paolo Arosio

“…In the search of DNA sequence variations affecting the individual predisposition to develop movement disorders, we scanned by DHPLC the exons and intronic boundary regions of ceruloplasmin, iron regulatory protein 2, hemopexin, hepcidin and hemojuvelin genes in cohorts of subjects affected by Parkinson's disease and idiopathic neurodegeneration with brain iron accumulation (NBIA). …”
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Advancing Horticultural Crop Loss Reduction Through Robotic and AI Technologies: Innovations, Applications, and Practical Implications by H. W. Gammanpila, M. A. Nethmini Sashika, S. V. G. N. Priyadarshani

“…These technological applications offer a pathway to enhanced productivity, reduced losses, and greater sustainability in horticulture. As we move forward, it is imperative to continue advancing and integrating these technologies, fostering innovation and collaboration between technology developers and the farming community.…”
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Dynamic Detection of Monocyte Subsets in Peripheral Blood of Patients with Acute Hypertriglyceridemic Pancreatitis by Junyuan Zheng, Junjie Fan, Chunlan Huang, Yingying Lu, Zehua Huang, Xingpeng Wang, Yue Zeng

“…Peripheral blood CD14+CD86+ M1 and CD14+CD206+ M2 monocytes were examined by flow cytometry on days 1, 3, and 7 after admission. Results. We found a marked increase in total and M1 monocyte count in AP patients (P<0.05). …”
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