Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of t... by Felix C. K. Wong, Angela Z. Chan, W. S. Wong, Angel H. W. Kwan, Tracy S. M. Law, Jacqueline P. W. Chung, Jeffrey S. S. Kwok, Angel O. K. Chan

“…We describe a case of a 24-year-old overweight woman who presented with hirsutism, secondary amenorrhea, clitoromegaly, and symptoms of diabetes mellitus (DM). …”
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Utility of Endoscopic Examination in the Diagnosis of Acute Graft-versus-Host Disease in the Lower Gastrointestinal Tract by Kosuke Nomura, Toshiro Iizuka, Daisuke Kaji, Hisashi Yamamoto, Yasutaka Kuribayashi, Masami Tanaka, Tsukasa Furuhata, Satoshi Yamashita, Daisuke Kikuchi, Akira Matsui, Toshifumi Mitani, Yasunori Ota, Shuichi Taniguchi, Shu Hoteya

“…Background and Aims. We retrospectively investigated the incidence of acute graft-versus-host disease (GVHD) in the lower gastrointestinal (GI) tract and the diagnostic accuracy of endoscopy. …”
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DEFORMATION PRACTICES OF SOCIAL REALITY INTEGRITY: OBJECTIFICATION OF DESIRES AS THE INHERITANCE OF CIVILIZATION PROGRESS by Yuliia Yu. Brodetskaya

“…This pattern of consumption determines the gap between a real purpose of the things and their contrived sense that gives them the desired effect (prestige, power, material wealth, etc.). In this situation, we can see updating of the tendency when things lose their true purpose, and man loses his active role. …”
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Diminished Expression of Complement Regulatory Proteins on Peripheral Blood Cells from Systemic Lupus Erythematosus Patients by Ana Paula Alegretti, Laiana Schneider, Amanda Kirchner Piccoli, Odirlei Andre Monticielo, Priscila Schmidt Lora, João Carlos Tavares Brenol, Ricardo Machado Xavier

“…Compared with healthy controls, we observed in SLE patients with lymphopenia and neutropenia decreased expression of CD55, CD59, and CD46 (𝑃<0.05). …”
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Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species by Lucille C. Jonas, Lucille C. Jonas, Curtis R. Youngs, Stephan Schmitz-Esser, Stephan Schmitz-Esser

“…To address this variability, we conducted a combined analysis of publicly available 16S rRNA gene amplicon sequencing datasets to reveal the core vaginal microbiota in cattle, sheep, and pigs. …”
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Thermal properties and non-bonded interactions in human PMP2 variants: A molecular dynamics study by Prabin Aryal, Jhulan Powrel

“…In this research work, we have done a comparative molecular dynamics study on the PMP2 protein and its M114T mutant variant, focusing on non-bonded interactions and thermal properties in a biologically relevant environment. …”
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Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats by Yuanhang Wu, Jianlin Wu, Zhikun Lin, Qian Wang, Ying Li, Aman Wang, Xiu Shan, Jiwei Liu

“…Previous research has demonstrated that a probiotic mixture (Bifidobacterium brevis, Lactobacillus acidophilus, Lactobacillus casei, and Streptococcus thermophilus) can ameliorate chemotherapy-induced mucositis and dysbiosis in rats, but the underlying mechanism has not been completely elucidated. We aimed to determine the inhibitory effects of the probiotic mixture on cisplatin-induced mucositis and pica and the underlying mechanism, focusing on the levels of 5-hydroxytryptamine (5-HT, serotonin) regulated by the gut microbiota. …”
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Patterns and Drivers of Surface Energy Flux in the Alpine Meadow Ecosystem in the Qilian Mountains, Northwest China by Yongxin Tian, Zhangwen Liu, Yanwei Fan, Yongyuan Li, Hu Tao, Chuntan Han, Xinmao Ao, Rensheng Chen

“…Using the Bowen ratio energy balance method, we monitored energy changes during the growing and non-growing seasons from 2022 to 2023. …”
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The Diagnostic Challenge of an Infrequent Spectrum of Cryptococcus Infection by Francisco Barbosa De Araujo Neto, Camila Corona De Godoy Bueno, Liege Tambelini Gomes, Daniela Alejandra Ortiz Navas, Mark Wanderley, Stefanie Gallotti Borges Carneiro, Rita Karine Veras Gomes De Mello, Laura Mendes Coura, Larissa Sayuri Missumi, Henrique Durante, Ricardo Francisco Cintra Zagatti, Márcio Valente Yamada Sawamura

“…Long term antifungal therapy is recommended, but surgical procedures may eventually be necessary when large thoracic symptomatic masses are present. We report a case of a 41-year-old male, immunocompetent, investigating a palpable mass in the left supraclavicular region associated with unintentional weight loss over the last three months. …”
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Meta-analysis of nifedipine and enalapril combination therapy for hypertensive patients with coronary heart disease: A systematic review and meta-analysis by Kun Wang, Wenchao Ma, Leina Sun, Fangcheng Su

“…To analyze and assess the clinical impact of nifedipine combined with enalapril on hypertension complicated with coronary heart disease, and provide evidence for rational drug use in clinic. Methods: We employed a revised version of the Jadad scale to assess the quality of the research literature following a rigorous screening process. …”
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Learnings from COVID-19 Forced Lockdown on Regional Air Quality and Mitigation Potential for South Asia by Abhishek Upadhyay, Parth Sarathi Mahapatra, Praveen Kumar Singh, Sishir Dahal, Suresh Pokhrel, Amit Bhujel, Indu Bikram Joshi, Shankar Prasad Paudel, Siva Praveen Puppala, Bhupesh Adhikary

“…In this context the country lockdown initiated to combat the COVID-19 pandemic (during March and April 2020 that is the pre-monsoon season) provides an unique opportunity for studying the relative impacts of different emission sources in the region. Here, we analyze changes in levels of air quality species across the region during selected lockdown periods using satellite and in-situ datasets. …”
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An antibacterial, antioxidant and hemostatic hydrogel accelerates infectious wound healing by Ziyi Zhou, Dengjun Zhang, Xuchao Ning, Linbo Jin, Yijing Lin, Chen Liang, Xin Wen, Tianhao Huang, Junli Zhou, Yiming Zhang

“…Furthermore, the HA@TA-Okra system significantly outperformed conventional dressings in terms of hemostatic performance in a rat hemorrhage model. We further evaluated the repair role of HA@TA-Okra system in vivo by establishing an animal model of full-thickness skin defects and a model of infected total skin defects. …”
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Thermal Development, Mortality, and Fertility of an Apulian Strain of <i>Drosophila suzukii</i> at Different Temperatures by Nuray Baser, Luca Rossini, Gianfranco Anfora, Kürşat Mustafa Temel, Stefania Gualano, Emanuele Garone, Franco Santoro

“…The dataset was first analysed according to life tables studies; then, we also estimated the biological parameters of the most common equations describing development, mortality, and fertility involved in physiologically-based model applications. …”
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Development and characterization of a line with substitution of chromosome 4B of wheat <i>Triticum aestivum</i> L. on chromosome 4H^<i>mar</i> of wild barley <i>Hordeum... by L. A. Pershina, N. V. Trubacheeva, V. K. Shumny, E. D. Badaeva

“…This study aimed to evaluate the possibility of introgression of H. marinum chromosomes into the genome of bread wheat using an incomplete amphiploid H. marinum ssp. gussoneanum (4x)–T. aestivum (Pyrotrix 28) (2n = 54) carrying the cytoplasm of wild barley. For this purpose, we crossed the line of bread wheat variety Pyrotrix 28 with an incomplete amphiploid, and then selected cytogenetically stable 42­chromosome plants with a high level of fertility in hybrid progeny. …”
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Evolution of Magnetic Reconnection in an Electron-scale Current Sheet by Yundan Guan, Quanming Lu, San Lu, Rongsheng Wang

“…In this paper, by performing a 2.5-dimensional particle-in-cell simulation, we investigate the evolution of electron-only magnetic reconnection to standard magnetic reconnection in a current sheet, whose initial width is of the electron inertial length. …”
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Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…Moreover. inflammatory responses were mitigated, as indicated by reductions in the expression of tumor necrosis factor-alpha and interleukin-6, and we detected reduction in the levels of alanine aminotransferase and aspartate aminotransferase, thereby indicating hepatoprotective effects. …”
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Critical band-to-band-tunnelling based optoelectronic memory by Hangyu Xu, Runzhang Xie, Jinshui Miao, Zhenhan Zhang, Haonan Ge, Xuming Shi, Min Luo, Jinjin Wang, Tangxin Li, Xiao Fu, Johnny C. Ho, Peng Zhou, Fang Wang, Weida Hu

“…Here, for the first time, we propose a critical band-to-band tunnelling (BTBT) based device that combines sensing, integration and memory functions. …”
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Frailty Status, Not Just Age, is Associated With Postoperative Opioid Consumption: A Retrospective, Population-based Analysis by Kyle R. Latack, MD, Ryan Howard, MD, Mark C. Bicket, MD, PhD, Samantha Cooley, MSW, Vidhya Gunaseelan, MBA, MS, MHA, Michael Englesbe, MD, Jennifer Waljee, MD, MPH, MS

“…Although prior studies suggest that older individuals may require less opioid following surgery, chronologic age, and frailty do not always align, and little is known regarding postoperative opioid consumption patterns by frailty. Methods:. We conducted a retrospective analysis of opioid-naïve adult patients undergoing common general, vascular, and gynecologic procedures across a statewide quality improvement program from November 6, 2017 to February 28, 2021. …”
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Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient by Qiwen Zheng, Xiangji Jin, Trang Thi Minh Nguyen, Eun-Ji Yi, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

“…This study investigates HD’s potential to counteract skin photoaging by restoring mitochondrial autophagy in keratinocytes. We used HPLC to detect the main chemical components in HD and, using a UVB-induced photoaging model in HaCaT keratinocytes, examined the effects of HD on reactive oxygen species (ROS) levels, Ca²⁺ concentration, mitochondrial membrane potential (MMP), apoptosis, and the cell cycle. …”
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Contribution of the Geodiversity knowledge to social, economic, and environmental health development by Cassio Silva, Edson Farias Mello, Gilberto Dias Calaes, Patricia Duringer Jacques, André Luiz Invernizzi

“…This applies to public institutions, civil society organizations, private companies, and watershed committees, aiding in the formulation of Regional Development Plans, Ecological-Economic Zoning, Territorial Planning, and strategies for the utilization of continental shelves, coastal environments, and accident prevention. We are entirely dependent on the geological characteristics of natural environments, as they provide the raw materials—such as minerals, water, and food—necessary for our survival and socio-economic development. …”
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