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69681
Biophysical Insights into Cancer Transformation and Treatment
Published 2013-01-01“…Biochemical energy is transformed into work of physical forces required for various biological functions. We postulate that energy transduction depends on endogenous electrodynamic fields generated by microtubules. …”
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69682
Effect of the High-FODMAP Diet on Bowel Preparation for Colonoscopy: A Multicenter, Prospective Cohort Study
Published 2020-01-01“…The high-FODMAP diet significantly reduced the quality of bowel preparation. We recommend the consumption of nonhigh-FODMAP diet in bowel preparation as a reference standard for dietary regimen. …”
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69683
Development, implementation and evaluation of consultation case-based learning course to improve the interdisciplinary clinical reasoning ability-a pilot study from nephrology
Published 2025-01-01“…Methods An interdisciplinary course on clinical reasoning was developed for residents based on ADDIE (Analysis, Design, Development, Implementation, and Evaluation) model. We collected frequently encountered consultation cases as our teaching resources with the methods of scenario case-based learning. …”
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69684
Relationship between TyG-related index and hearing loss in people over 45 s in China
Published 2025-02-01“…This study investigates the association of the TyG index, BMI index, and TyG-BMI index with hearing loss, with a focus on their potential implications for the aging population.MethodsData from the China Health and Retirement Longitudinal Study (CHARLS) database were analyzed using R software. We applied multi-factor logistic regression, linear regression, restricted cubic splines, and subgroup analyses to assess the impact of the TyG index, BMI index, and TyG-BMI index on hearing loss across different age groups.ResultsThe TyG index was not significantly associated with hearing loss. …”
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69685
Stress during Lactation Induces Insulin Resistance Associated with an Increase in Type 1 Cannabinoid Receptors in Liver and Adipose Tissue
Published 2019-01-01“…Several reports have shown that stress during lactation causes long-term metabolic and hormonal disruptions. In this study, we designed experiments to evaluate the effects of stress during lactation on the abundance of Type 1 cannabinoid/endocannabinoid receptors (CB1R) in epididymal fat and liver and development of insulin resistance in adult mice. …”
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69686
3D Point Cloud from Millimeter-wave Radar for Human Action Recognition: Dataset and Method
Published 2025-02-01“…To overcome these issues, we present a 3D point cloud dataset tailored for human actions captured using millimeter-wave radar (mmWave-3DPCHM-1.0). …”
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69687
Plant Detection in RGB Images from Unmanned Aerial Vehicles Using Segmentation by Deep Learning and an Impact of Model Accuracy on Downstream Analysis
Published 2025-01-01“…Additionally, 17 existing datasets of various spatial resolutions and markup quality levels from the Roboflow service were used to extend training image sets. Finally, we compared several texture features between manually evaluated and neural-network-estimated plant masks. …”
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69688
Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring
Published 2018-01-01“…Moreover, the ratio of reduced glutathione levels between I/NI conditions was higher in OFF and CENT compared to the other groups in almost all the subsets. Finally, we observed significant correlations between the response to the induced oxidative stress and the degree of methylation in specific genes on the oxidative stress pathway. …”
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69689
Tongue-LiteSAM: A Lightweight Model for Tongue Image Segmentation With Zero-Shot
Published 2025-01-01“…This study aims to construct an efficient model with zero-shot suitable for tongue image segmentation in TCM. Methods: We developed the Tongue-LiteSAM model by improving the SAM (Segment Anything Model) framework to suit tongue segmentation. …”
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69690
Related studies on measuring the normal values of optic nerve sheath diameter in healthy Chinese adults based on CT scans
Published 2025-02-01“…The comparison of parameters between different genders showed that the values of all parameters in males were greater than those in females, and the difference between the two groups was statistically significant (P < 0.001). In addition, we further measured the ONSD/ETD values, which averaged 0.24 (0.23–0.24) at 3 mm and 0.19 (0.19–0.20) at 10 mm. …”
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69691
Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse
Published 2014-01-01“…Wild type, Wfs1 heterozygous, and homozygous mice were treated with VPA for three months (300 mg/kg i.p. daily) and gene expression profiles in liver were evaluated using Affymetrix Mouse GeneChip 1.0 ST array. We identified 42 genes affected by Wfs1 genotype, 10 genes regulated by VPA treatment, and 9 genes whose regulation by VPA was dependent on genotype. …”
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69692
Non-Alcoholic Fatty Liver Disease in Cardiac Patients with Overweight and Obesity
Published 2019-01-01“…Aim. In this research, we set out to study organic changes in the heart and blood vessels of obese men suffering from non-alcoholic fatty liver disease (NAFLD) combined with cardiac pathology in the metabolically unhealthy phenotype (MUHP). …”
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69693
Light exposure profiles differ between myopes and non-myopes outside school hours
Published 2024-05-01“…Purpose Considering the putative role of light in myopia, and variations in socioeconomic, lifestyle, educational and environmental factors across ethnicities, we objectively investigated light exposure patterns in Indian school children.Methods The light exposure profile of 143 school children (9–15 years, 50 myopes) recorded using a validated wearable light tracker for six continuous days was analysed. …”
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69694
Oxidative stress caused by 3-monochloro-1,2-propanediol provokes intestinal stem cell hyperproliferation and the protective role of quercetin
Published 2025-02-01“…However, the specific impacts and mechanisms of 3-MCPD on intestinal health remain elusive. Here, we employed the adult intestine of Drosophila melanogaster, a notable invertebrate model organism, to investigate the intestinal toxicity of 3-MCPD and its underlying mechanisms. …”
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69695
Chemical Constituents and Anti-Inflammatory Effect of Incense Smoke from Agarwood Determined by GC-MS
Published 2020-01-01“…The agarwoods were produced by the whole-tree agarwood-inducing technique (AWIT), agarwood induced by axe wounds (AAW), burning-chisel-drilling agarwood (BCDA), wood of Aquilaria sinensis trees (AS), respectively. Herein, we used GC-MS to analyze the chemical constituents of incense smoke generated from AWIT, AAW, BCDA, AS, and the extracts of sticks from agarwood produced by the whole-tree agarwood-inducing technique (EAWIT), and 484 compounds were identified. …”
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69696
Differences in immune-related toxicity between PD-1 and PD-L1 inhibitors: a retrospective cohort study in patients with advanced cancer
Published 2024-11-01“…This study aimed to investigate differences in IRAEs between patients with advanced solid malignances treated with PD-L1 and PD-1 inhibitors in a real-world setting. We conducted a retrospective cohort study at four Swedish Regions. …”
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69697
Pigmented Maize (Zea mays L.) Contains Anthocyanins with Potential Therapeutic Action Against Oxidative Stress - A Review
Published 2020-03-01“…Could the maize anthocyanins play a curative, preventive or complementary role in the treatment of chronic diseases? Here, we describe the occurrence of anthocyanins from pigmented maize and their chemical structures. …”
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69698
Clinical Dental Midline Shift Is Not a Predictor of the Side of Shorter Hemimandible: A Cone Beam Computed Tomography Diagnostic Study
Published 2025-01-01“…Tomographic images were acquired using the i-CAT<sup>®</sup> Imaging System; mandibular/maxillary measurements were obtained with the Planmeca Romexis<sup>®</sup> software v.6.This is an ancillary study of a clinical trial (NCT02144233) that included chronic pain (TMD diagnosis; DC/TMD criteria), fully dentate, and stable normo-occlusion participants. <b>Results</b>: We found sixteen (42.1%) dental midline deviations to the right and thirteen (34.2%) to the left. …”
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69699
Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites
Published 2024-12-01“…This study investigated the impact of Bifidobacterium animalis subsp. lactis Probio-M8 (Probio-M8) on old mice and sarcopenia patients. We analyzed 43 subjects, including gut microbiome, fecal metabolome, and serum metabolome, using a multi-omics approach to assess whether Probio-M8 can improve sarcopenia by modulating gut microbial metabolites. …”
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69700
tDCS cranial nerve Co-stimulation: Unveiling brainstem pathways involved in trigeminal nerve direct current stimulation in rats
Published 2025-03-01“…Methods: In this study, we examined the effects of acute transcutaneous TN direct current stimulation (TN-DCS) on tonic (i.e. mean spike rate) and phasic (number of bursts, spike rate per burst, burst duration, and inter-burst interval) activities while simultaneously recording single-neuron activity across three brainstem nuclei in rats: the locus coeruleus (LC; phasic and tonic activities), dorsal raphe nucleus (DRN; tonic activity), and median raphe nucleus (MnRN; tonic activity). …”
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