Colorectal Cancer and Polyps in Diverticulosis Patients: A 10-Year Retrospective Study in 13680 Patients by Fadi Abu Baker, Jesus Alonso Z'cruz De La Garza, Amir Mari, Abdel-Rauf Zeina, Amani Bishara, Oren Gal, Yael Kopelman

“…Diverticulosis, however, was associated with an increased polyp detection rate compared to controls (30.5% vs. 25.5%; odds ratio=1.2, P<0.001, and 95%CI=1.11‐1.299). Conclusion. We demonstrated that diverticulosis was not associated with an increased risk for CRC. …”
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QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration by Jayshree Advani, Puja A. Mehta, Andrew R. Hamel, Sudeep Mehrotra, Christina Kiel, Tobias Strunz, Ximena Corso-Díaz, Madeline Kwicklis, Freekje van Asten, Rinki Ratnapriya, Emily Y. Chew, Dena G. Hernandez, Sandra R. Montezuma, Deborah A. Ferrington, Bernhard H. F. Weber, Ayellet V. Segrè, Anand Swaroop

“…Abstract DNA methylation provides a crucial epigenetic mark linking genetic variations to environmental influence. We have analyzed array-based DNA methylation profiles of 160 human retinas with co-measured RNA-seq and >8 million genetic variants, uncovering sites of genetic regulation in cis (37,453 methylation quantitative trait loci and 12,505 expression quantitative trait loci) and 13,747 DNA methylation loci affecting gene expression, with over one-third specific to the retina. …”
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EMA/CO Combination Chemotheraphy in Gestational Trophoblastic Neoplasia: Update of Our Results by Tolga Taşçı, Işın Üreyen, Günsu Kimyon, Alper Karalök, Sevgi Koç, M. Faruk Köse, Gökhan Tulunay, Taner Turan

“… OBJECTIVE: In this study, we aimed updating our experience about the treatment success of EMA-CO (etoposide, methotrexate, actinomycin-D, cyclophosphamide, vincristine) chemotherapy in high-risk gestational trophoblastic neoplasia (GTN). …”
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Genotyping <em> Escherichia coli </em> O157:H7 strains isolated from cattle and small ruminants in Fars province (Iran) using Enterobacterial Repetitive Intergenic Consensus PCR A... by Sedigheh Mokhtari, Yahya Tahamtan, Mohammad Kargar, Keyvan Tadayon, Elham Moazamian

“…When shed in animal faeces, the bacteria can contaminate soil, water and food. Aim: We genotyped bacterial isolates and identified their genetic associations and source of origin in order to reduce the spread of infections and improve disease control. …”
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Turismo en Mallorca by Macià Blázquez Salom

“…Growthism, in Jason Hickle's apt definition, perpetuates this model as a solution to the contradictions inherent in capitalism, which are expressed in the form of crises such as those we are suffering as a result of the speculative financialization of the hotel industry (the Blackstone investment fund is now the largest hotel owner in Spain), the climate emergency or the worsening of social inequality. …”
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“It's a good idea, but…”: a qualitative evaluation of the GoldiCare intervention in Norwegian home care services by Heike Fischer, Fredrik Klæboe Lohne, Fredrik Klæboe Lohne, Marius Steiro Fimland, Skender Elez Redzovic

“…The objective of this qualitative process evaluation study was to gain insights into how the implementation outcomes of acceptability, appropriateness, feasibility, adoption and fidelity, respectively, impacted the implementation of the GoldiCare intervention.MethodsWe conducted ten individual interviews with operations managers and five focus group interviews with home care workers from the intervention units. …”
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The Feasibility and Acceptability of a Community Science Approach to Explore Infant Formula Preparation Safety in the Home by Sara Jones, Jonie Cooper, Abbie Dolling, Tara McNamara, Susan Dvorak, Vicky Sibson, Amy Brown, Emma Yhnell, Phyll Buchanan, Sharon Breward, Rebecca Ellis, Aimee Grant

“…Parents often seek out information about health and parenting topics, but despite this, there have been few attempts to actively engage them in the research process. We aimed to assess the feasibility and acceptability of using community science (CS) in a pilot study to explore infant formula preparation safety in the home in the United Kingdom. …”
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Opinions on hypertension care and therapy adherence at the healthcare provider and healthcare system level: a qualitative study in the Hague, Netherlands by Mattijs E Numans, Michiel L Bots, Sytske van Bruggen, Hedwig M M Vos, Rimke C Vos, Guy Rutten, Saskia E van Grondelle, Judith Meijer, Erik van Duin

“…Since the latter two levels are often overlooked, we wished to explore facilitators and barriers on each of these levels in relation to hypertension care for people with hypertension, with a specific focus on therapy adherence.Design Qualitative study using focus groups of healthcare providers. …”
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CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite by Juliana Costa Ferreira Neves, Hiochelson Najibe Santos Ibiapina, Fábio Magalhães-Gama, Jacqueline Almeida Gonçalves Sachett, Iran Mendonça Silva, Kerolaine Fonseca Coelho, Eliane Campos Alves, Andréa Monteiro Tarragô, Luiz Carlos de Lima Ferreira, Adriana Malheiro, Wuelton Marcelo Monteiro, Allyson Guimarães Costa

“…These soluble immunological molecules act by modulating the inflammatory response; however, the mechanisms associated with the development of AKI are still poorly understood. Here, we characterize the profile of these soluble immunological molecules as possible predictive biomarkers of the development of AKI. …”
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Optimizing hypoglycaemia prediction in type 1 diabetes with Ensemble Machine Learning modeling by Daphne N. Katsarou, Eleni I. Georga, Maria A. Christou, Panagiota A. Christou, Stelios Tigas, Costas Papaloukas, Dimitrios I. Fotiadis

“…Methods In this study, we propose an ensemble univariate short-term predictive model of the subcutaneous glucose concentration in T1D targeting at improving its error in the hypoglycaemic region. …”
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Impact of multimorbidity on long-term outcomes in older adults with non-ST elevation acute coronary syndrome in the North East of England: a multi-centre cohort study of patients u... by Chris Wilkinson, Vijay Kunadian, Benjamin Beska, Abdulla A Damluji, Hanna Ratcovich, Greg B Mills

“…Objectives Older adults have a higher degree of multimorbidity, which may adversely affect longer term outcomes from non-ST elevation acute coronary syndrome (NSTE-ACS). We investigated the impact of multimorbidity on cardiovascular outcomes 5 years after invasive management of NSTE-ACS.Design Prospective cohort study.Setting Multicentre study conducted in the north of England.Participants 298 patients aged ≥75 years with NSTE-ACS and referred for coronary angiography, with 264 (88.0%) completing 5-year follow-up.Main outcome measures Multimorbidity was evaluated at baseline with the Charlson comorbidity index (CCI). …”
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Medicaid Eligibility and Time to Re-incarceration Among Previously Incarcerated Subjects With Schizophrenia by Chris Kozma, Michael Dickson, Jacqueline Pesa, Carmela J. Benson

“…However, under federal law, states must either suspend or terminate eligibility once they are incarcerated. We hypothesize that prompt re-acquisition of Medicaid eligibility following release from incarceration lowers the risk of re-incarceration. …”
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A systematic review of outcomes reported in studies to optimise the medication use of patients at hospital discharge by Joke Wuyts, Veerle Foulon, Samuel Sebastian Allemann, Fabienne Boeni

“…This literature review aimed at collecting outcomes from studies investigating how to optimise medication use of patients following hospital discharge, and to categorise them, as a first step in the development of a core outcome set. Methods We systematically reviewed quantitative and qualitative literature using Embase, PubMed, CINAHL and the EU Clinical Trial Register databases. …”
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Immune modulation effects of curcumin in pristane-induced lupus mice by Handono Kalim, Kusworini Handono, Takhta Khalasha, Mirza Zaka Pratama, Tri Wahyudi Iman Dantara, Ayu Pramitha Wulandari, Fahimma Albinsaid, Sofi Nur Fitria, Muhammad Vardian Mahardika

“…Meanwhile, intraperitoneal (i.p.) injection of the hydrocarbon oil pristane into normal mice leads to a lupus-like autoimmune syndrome. We aimed to investigate the effects of curcumin on systemic lupus erythematosus (SLE) clinical manifestation, adaptive immune system components, proinflammatory cytokines, and autoantibody production in pristane-induced lupus mice. …”
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Mt or not Mt: Temporal variation in detection probability in spatial capture-recapture and occupancy models by Sollmann, Rahel

“…An occupancy case study for ten bird species with a more complex model structure showed considerable differences in occupancy parameter estimates under models accounting for or ignoring temporal variation in detection; but estimates and predictions from the latter were always within 95% confidence intervals of the former. There are cases where we cannot or may not want to ignore temporal variation in detection: a behavioral response to detection and certain SCR observation models do not allow collapsing data across sampling occasions; and temporal variation in detection may be informative of species phenology/behavior or for future study planning. …”
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Endoscopy-assisted anterior cervical discectomy and fusion with internal fixation vs conventional surgery in the treatment of cervical disc herniation by Haicun Zhang, Yanbo Lin, Canglu Wu, Fangling Cheng, Danqing Bao, Yuyan Chen

“…Initially, it is treated conservatively; however, complex and resistant cases may require a surgical intervention. Aim: We aimed to compare the clinical effect of endoscopy-assisted anterior cervical discectomy and fusion (ACDF) with internal fixation and conventional surgery in the treatment of CDH. …”
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Does Differential Habitat Selection Facilitate Coexistence Between Badgers and Hedgehogs? by Katie A. Lee, Antonio Uzal, Louise K. Gentle, Philip J. Baker, Richard J. Delahay, Anthony Sévêque, Robert S. Davis, Richard W. Yarnell

“…Previous studies have shown spatial separation between these species and attributed this to hedgehogs experiencing a ‘landscape of fear’, but little is known about the potential role of differential habitat use. We estimated the density and occupancy of both species at 22 rural study sites in England and Wales, to explore whether food availability, habitat or the presence of badgers, explained hedgehog distributions. …”
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Fracture, Dissolution, and Cementation Events in Ordovician Carbonate Reservoirs, Tarim Basin, NW China by Vinyet Baqués, Estibalitz Ukar, Stephen E. Laubach, Stephanie R. Forstner, András Fall

“…Using 227 samples from 16 cores, we document textures and cement compositions bearing on cavity histories with petrographic, high-resolution scanning electron microscopy (SEM), isotopic, and fluid inclusion microthermometric observations. …”
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Optimizing water-use efficiency under elevated CO₂: A meta-analysis of crop type, soil modulation, and enrichment methods by Ali Mokhtar, Hongming He, Samar Attaher, Ali Salem, Muneer Alam

“…Therefore, in this study, we have conducted a meta-analysis to quantitative statistical means among studies and discuss how WUE responds to eCO2 under pathway (C3 and C4), four enrichment methods and soil types based on 124 peer-reviewed studies and 1474 observations to provide an in-depth overview of how these factors interact under future CO₂ scenarios. …”
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Comparative efficacy of clopidogrel-aspirin combination therapy versus aspirin monotherapy in preventing recurrent events in transient ischemic attack and minor stroke: a systemati... by Ahmad Mujtaba Bhutto, Rana Ali Raza, Mohammad Bilal Abbasi, Iman Jauhar, Naeemullah Arbani, Muhammad Mubashir, Abdul Raheem, Taha Basit Ameen, Syed Muhammad Sinaan Ali

“…This meta-analysis aims to evaluate the efficacy and safety of DAPT compared to aspirin monotherapy in preventing recurrent stroke. Methods We performed a systematic search of electronic databases including PubMed, MEDLINE, Embase, and Scopus up to April 1, 2024. …”
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