Quantitative Determination of 18-β-Glycyrrhetinic Acid in HepG2 Cell Line by High Performance Liquid Chromatography Method by Giuseppina Nocca, Cinzia Callà, Stefano Angelo Santini, Adriana Amalfitano, Luca Marigo, Diana Valeria Rossetti, Gianrico Spagnuolo, Massimo Cordaro

“…The intracellular GA concentration value, obtained as mean of five different determinations, was 45.8 ± 7.45 μg/mL. We have developed a HPLC-UV method for quantitative determination of GA inside cells, with advantages in the cost reduction and economy of the analytical process.…”
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Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury by Susan Bengs, Alexia Rossi, Martina Haberecker, Nidaa Mikail, Alexander Meisel, Achi Haider, Muriel Grämer, Angela Portmann, Atanas Todorov, Christof Schönenberger, Caroline E. Gebhard, Gabriela M. Kuster, Vera Regitz-Zagrosek, Catherine Gebhard

“…However, clinical studies addressing this association have yielded conflicting results. We sought to analyze the impact of sex hormones, age, and cardiovascular disease on ACE-2 and TMPRSS-2 expression in different mouse models. …”
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Analysis of Mammography BI-RADS Distribution and Follow-up Ultrasound Assessment: A Single-Center Study by Kankaya B, Buyukasik S, Altundal YE, Topcu FS, Rahmanbakhsh P, Etemad A, Kapan S, Alis H

“…Our goal was to evaluate potential gaps in the current breast cancer screening process by analyzing BI-RADS classifications, follow-up completion rates, and outcomes of completed ultrasound examinations.Patients and Methods: This retrospective study analyzed 1761 Turkish women who underwent screening mammography from 2020– 2022 at the Istanbul Aydin University General Surgery Clinic, Istanbul, Turkey. We assessed the distribution of BI-RADS classifications, analyzed the frequency and non-completion rates of recommended follow-up US, and examined the outcomes of completed follow-up US examinations. …”
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A Comparison of Rice Root Microbial Dynamics in Organic and Conventional Paddy Fields by Fangming Zhu, Takehiro Kamiya, Toru Fujiwara, Masayoshi Hashimoto, Siyu Gong, Jindong Wu, Hiromi Nakanishi, Masaru Fujimoto

“…Understanding the roles of root-associated microbiomes in rice development requires dissecting their assembly throughout the rice life cycle under diverse environments and exploring correlations with soil properties and rice physiology. In this study, we performed amplicon sequencing targeting fungal ITS and the bacterial 16S rRNA gene to characterize and compare bacterial and fungal community dynamics of the rice root endosphere and soil in organic and conventional paddy fields. …”
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Diabetes Mellitus Is Associated with a Lower Risk of Gout: A Meta-Analysis of Observational Studies by Xiaoli Li, Lianju Li, Yuling Xing, Tiantian Cheng, Shaohui Ren, Huijuan Ma

“…Although several epidemiological studies have investigated the relationship between diabetes mellitus (DM) and the risk of gout, the results are inconsistent. Therefore, we systematically retrospected available observational studies to clarify the impact of DM on the risk of gout. …”
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Effect of delivery hospital busyness on early mortality in small preterm infants: a Finnish population-based cohort study in 2006–2016 by Mika Gissler, Sari Räisänen, Seppo Heinonen, Sture Andersson, Riitta Vilkko, Markus Leskinen

“…Objectives To evaluate the effect of delivery hospital busyness on the postnatal condition and the perinatal mortality among small preterm infants born at ≤32+0 gestational weeks.Design The daily delivery volume distribution is defined as lowest 10% (‘quiet’) and highest 10% (‘busy’) delivery-volume days, and days between (80%) as optimal delivery-volume days. We analysed differences in the incidence of selected adverse outcomes between quiet and busy days compared with optimal delivery-volume days by logistic regression followed by crude (ORs) and adjusted ORs (aORs) with 99% CIs.Setting A population-based cohort study based on prospectively collected real-world data from five university hospitals and 21 non-tertiary-level delivery hospitals in Finland, 2006‒2016.Participants 4323 small preterm infants.Primary outcome measures Umbilical cord pH ≤7.05, Apgar score 0–3 points at the age of 1 min, Apgar score 0–3 points at age 5 min, birth asphyxia (International Classification of Diseases-10 code), resuscitation with intubation.Secondary outcome measures Perinatal mortality comprising stillbirths and early neonatal deaths (<7 days).Results Busy days (busy vs optimal) showed no correlation with the primary birth-related outcomes. …”
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The frequency of mutations in advanced thyroid cancer in Japan: a single-center study by Soji Toda, Hiroyuki Iwasaki, Yoichiro Okubo, Hiroyuki Hayashi, Mei Kadoya, Hiroyuki Takahashi, Tomoyuki Yokose, Yukihiko Hiroshima, Katsuhiko Masudo

“…We analyzed the outcomes of genetic testing to study the frequency of mutations in advanced thyroid cancer in Japan. …”
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An Adaptive Message Passing MPSoC Framework by Gabriel Marchesan Almeida, Gilles Sassatelli, Pascal Benoit, Nicolas Saint-Jean, Sameer Varyani, Lionel Torres, Michel Robert

“…The work presented in this paper relies on a homogeneous NoC-based MPSoC framework we developed for exploring scalable and adaptive on-line continuous mapping techniques. …”
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Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro by Zhou Zhou, Weiliang Sun, Ying Liang, Yanxiang Gao, Wei Kong, Youfei Guan, Juan Feng, Xian Wang

“…However, the link between fenofibrate and Th17 cells is lacking. In the present study, we hypothesized that fenofibrate inhibited the differentiation of Th17 cells. …”
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A case of 49,XXXYY followed-up from infancy to adulthood with review of literature by Junko Kanno, Akinobu Miura, Sayaka Kawashima, Hirohito Shima, Dai Suzuki, Miki Kamimura, Ikuma Fujiwara, Masayuki Kamimura, Mitsugu Uematsu, Masataka Kudo, Atsuo Kikuchi

“…Aneuploidy of the X chromosome can lead to various progressive complications due to excess X chromosomes. Herein, we present the case of a Japanese man with 49,XXXYY. …”
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Knowledge of and Adherence to Anaemia Prevention Strategies among Pregnant Women Attending Antenatal Care Facilities in Juaboso District in Western-North Region, Ghana by Prince Kubi Appiah, Daniel Nkuah, Duut Abdulai Bonchel

“…However, anaemia in pregnancy and its consequences could be devastating to all stakeholders if actions are not taken to reduce the phenomenon. Therefore, we recommend that more education and sensitisation programs including good nutritional practices in the diet of pregnant women be promoted to increase awareness and adherence to anaemia prevention strategies among pregnant women in the Juaboso District.…”
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Simultaneous Determination of Night Effective Constituents and Correlation Analysis of Multiconstituents and Antiplatelet Aggregation Bioactivity In Vitro in Chuanxiong Rhizoma Sub... by Peihua Zhang, Linming Chen, Xiaoxiao Wang, Jinpei Chen, Shungui Xu, Ling Ye, Yixin Yao

“…Traditional Chinese medicine mainly involves decoction, and the content of effective constituents and antiplatelet aggregation bioactivity (AAB) in CR may vary with different decoction time (10 min, 20 min, 30 min, 40 min, 50 min, and 60 min). Here, we showed that coniferyl ferulate and levistilide A were detected in CR material, but not in the decoction. …”
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Treatment of Severe Hypercapnic Respiratory Failure Caused by SARS-CoV-2 Lung Injury with ECCO2R Using the Hemolung Respiratory Assist System by Ramiro Saavedra-Romero, Francisco Paz, John M. Litell, Julia Weinkauf, Carina C. Benson, Lisa Tindell, Kari Williams

“…A mechanism to prevent progressive hypercapnia may offset hemodynamic instability among patients who develop hypercapnia. We present the case of a woman in her mid-60’s with severe acute hypercapnic respiratory failure secondary to COVID-19 pneumonia who was successfully treated with early implementation of lung-protective ventilation facilitated by extracorporeal carbon dioxide removal (ECCO2R). …”
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The book graphics of Vilnius printing houses in XVI-XVII centuries by Jolita Liškevičienė

“… The printing activities flourished in Vilnius from the end of the sixteenth century. We may talk about two periods with distinctive features in book illustration in relation to printed book graphics: 1) the end of the sixteenth century to the 1640s; 2) the 1640s to the end of the seventeenth century. …”
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Expression of auxin transporter genes in flax (<i>Linum usitatissimum</i>) fibers during gravity response by N. N. Ibragimova, N. E. Mokshina

“…Gravitropism is an adaptive reaction of plants associated with the ability of various plant organs to be located and to grow in a certain direction relative to the gravity vector, while usually the asymmetric distribution of the phytohormone auxin is a necessary condition for the gravitropical bending of plant organs. Earlier, we described significant morphological changes in phloem fibers with a thickened cell wall located on different sides of the stem in the area of the gravitropic curvature. …”
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Changes in Serum Natriuretic Peptide Levels after Percutaneous Closure of Small to Moderate Ventricular Septal Defects by Yuksel Kaya, Ramazan Akdemir, Huseyin Gunduz, Sani Murat, Orhan Bulut, İbrahim Kocayigit, M. Bulent Vatan, M. Akif Cakar, Ekrem Yeter, Harun Kilic, Mustafa Tarik Agac, Zeydin Acar

“…B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on brain natriuretic peptide levels. …”
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Predictors of irritability in pediatric autistic populations: a scoping review by Sara Alatrash, Sara Alatrash, Tithi Paul, Julia Carbone, Melanie Penner, Melanie Penner, Atena Roshan Fekr, Atena Roshan Fekr, Azadeh Kushki, Azadeh Kushki

“…While extensive research has focused on interventions to reduce irritability symptoms, the underlying correlates remain poorly understood. To address this, we conducted a scoping review of the literature examining factors contributing to irritability in pediatric autistic populations.MethodsA literature search of Embase, MEDLINE, PubMed, PsycINFO, and Web of Science was conducted in addition to manually retrieved papers from Google Scholar. …”
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Effect of alloying elements on the stacking fault energies of dilute al-based alloys by Gao Q., Zhang H., Yang R., Fan Z., Liu Y., Wang J., Geng X., Gao Y., Shang S., Du Y., Liu Z.

“…For the targeted elements, the calculations indicate that Na, Si, K, Ca, Sc, Ga, Ge, Sr, Zr, In, Sn, La, Hf, and Pb, in any concentration we considered, decrease the γSF of Al, while Ag, Be, Cd, Co, Cu, Cr, Fe, Li, Mn, Mg, Ni, Ti, V, and Zn increase the γSF of Al, when the concentration of alloying elements is 1.39 at. % in the system. …”
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Hypercalcemia and co-occurring TBX1 mutation in Glycogen Storage Disease Type Ib: case report by Zakaria Kasmi, Imane Ain El Hayat, Zahra Aadam, Abderrahmane Errami, Ibtihal Benhsaien, Jalila EL Bakkouri, Dalal Ben Sabbahia, Meryem Atrassi, Ahmed Aziz Bousfiha, Fatima Ailal

“…This disorder is characterized by impaired glycogenolysis and gluconeogenesis, resulting in clinical and metabolic manifestations. We report a three-month-old Moroccan female patient presenting with doll-like facies, hepatomegaly, dysmorphic features, and developmental delays. …”
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Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research by Chen H, Fu S, Zhi X, Wang Y, Liu F, Li Y, Ren F, Zhang J, Ren L, Wang Y

“…Recognizing the analogy between pain and touch processing patterns, we conclude by summarizing the interaction between touch and pain. …”
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