Boundary plasma studies for a spherical tokamak with lithium walls by A. Antony, L. Carbajal, T.D. Rognlien, M.V. Umansky, A. Froese, S. Howard, C. Ribeiro, R. Ivanov, C. Dunlea, C.P. McNally

“…Experimental edge temperature and density profiles from triple Langmuir probes are used to establish realistic temperature and density profiles in UEDGE Rognlien et al. (1992) by adjusting the transport coefficients. In UEDGE, we model the wall-limited plasma via a thin limiter with various insertion depths. …”
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Digital connection, real bonding: Brief online chats boost interpersonal closeness regardless of the conversational topic by Chiara Fini, Vanessa Era, Giovanna Cuomo, Ilenia Falcinelli, Mattia A. Gervasi, Matteo Candidi, Claudia Mazzuca, Marco Tullio Liuzza, Bodo Winter, Anna M. Borghi

“…The second experiment focused only on the interactive condition, where we examined interpersonal dynamics across different subcategories of abstract (e.g., philosophical/spiritual, emotional, social, physical/spatio-temporal) and concrete topics (e.g., tools, animals, food). …”
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Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights by Tobias Meindl, Alexander Hapfelmeier, Tobias Mantel, Angela Jochim, Jonas Deppe, Silke Zwirner, Jan S. Kirschke, Yong Li, Bernhard Haslinger

“…Conclusion Machine‐learning‐assisted classification of MR‐imaging biomarkers gathered in routine care can assist in the diagnosis of parkinsonian syndromes as part of the diagnostic workup. We provide a visual method that aids the interpretation of neuroimaging‐based classification results of the three main parkinsonian syndromes, improving clinical interpretability.…”
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Safety profile of EZH2 inhibitors for cancer: a systematic review and meta-analysis by Zhou Zhao, Xiufeng Chen, Huayang Pang, Yan Shi, Hao Sun

“…Objective To evaluate the safety profiles of EZH2-targeted inhibitors in cancer treatment, focusing on treatment-related adverse events (TRAEs) across various clinical trials. Methods We conducted a systematic review and meta-analysis using data from clinical trials involving EZH2 inhibitors reported up to May 31, 2024. …”
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Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease by Edgar Denova-Gutiérrez, Gerardo Huitrón-Bravo, Juan O. Talavera, Susana Castañón, Katia Gallegos-Carrillo, Yvonne Flores, Jorge Salmerón

“…A cross-sectional analysis was performed, using data from adults who participated in the HWCS baseline assessment. We collected information on participants' socio-demographic conditions, dietary patterns and physical activity via self-administered questionnaires. …”
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Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs by Felipe Beccaria Casagrande, Sabrina de Souza Ferreira, Fernanda Peixoto Barbosa Nunes, Lavínia Maria Dal’Mas Romera, Suelen Silvana dos Santos, Fernando Henrique Galvão Tessaro, Paula Regina Knox de Souza, Sandro Rogério Almeida, Joilson Oliveira Martins

“…Paracoccidioidomycosis, a key issue for Brazilian health service, can be aggravated in patients with impaired immunological responses, such as diabetic patients. We evaluated the role of insulin in inflammatory parameters in diabetic and nondiabetic mice using a systemic mycosis Paracoccidioides brasiliensis (Pb) model. …”
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Prophylactic Theophyline reduces birth asphyxia related renal injury in term neonates by Salma Aziz, Syeda Maimoona Qudrat, Tanzeela Rani, Qurat-ul-Ain Chughtai, Misbah Aziz, Rai Muhammad Asghar

“…So, in future renal function can be protected by introducing theophylline and by maintaining renal function we can reduce risk of mortality. KEY WORDS: birth asphyxia, Sarnat grading system, theophylline, mean glomerular filtration rate   …”
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Mesenchymal stem cell‐derived exosomes mitigate amyloid β‐induced retinal toxicity: Insights from rat model and cellular studies by Amanda Qarawani, Efrat Naaman, Rony Ben‐Zvi Elimelech, Michal Harel, Shahaf Sigal‐Dror, Tali Ben‐Zur, Tamar Ziv, Daniel Offen, Shiri Zayit‐Soudry

“…Through intravitreal injections in wild‐type rats and RPE‐like cell culture experiments, we examined the protective effects of AT‐MSC‐Exosomes against Aβ42 retinotoxicity. …”
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RNA-seq and In Vitro Experiments Reveal the Protective Effect of Curcumin against 5-Fluorouracil-Induced Intestinal Mucositis via IL-6/STAT3 Signaling Pathway by Xuan-ying Wang, Bo Zhang, Yi Lu, Lu Xu, Yi-jie Wang, Bi-yu Cai, Qing-hua Yao

“…Therefore, in this study, we investigated the effect of curcumin on inflammation, intestinal epithelial cell damage in an IM model. 5-FU was used to induce the model of IM in intestinal epithelial cells, and curcumin at different concentrations was administrated. …”
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Voluntary Forelimbs Exercise Reduces Immobilization-Induced Mechanical Hyperalgesia in the Rat Hind Paw by Kumiko Ishikawa, Satoshi Oga, Kyo Goto, Junya Sakamoto, Ryo Sasaki, Yuichiro Honda, Hideki Kataoka, Minoru Okita

“…However, it is unclear whether voluntary exercise reduces immobilization-induced hyperalgesia. We examined the effect of voluntary forelimb exercise on immobilized-induced hyperalgesia in hind paws of rats. …”
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Huge splenomegaly, a rare presentation of multicentric Castleman’s disease in an HIV-infected patient: a case report and literature review by Malihe Hasannezad, Abdolkarim Haji Ghadery, Sara Ghaderkhani, Armin Vazirian, Fereshteh Ameli, Farid Azmoudeh-Ardalan, Mohammad Reza Rafiian Naini, Ladan Abbasian

“…Histopathologic and immunohistochemical evaluation of excised lymph node as well as imaging modalities, such as computed tomography (CT) and magnetic resonance imaging, are required for the diagnosis of CD. Case description We present a case of 46-year-old HIV-infected woman with fever, weakness, weight loss, and splenomegaly in the past 18 months. …”
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A systematic scoping review of latent class analysis applied to accelerometry-assessed physical activity and sedentary behavior. by Michael Kebede, Annie Green Howard, Yumeng Ren, Blake Anuskiewicz, Chongzhi Di, Melissa A Troester, Kelly R Evenson

“…<h4>Background</h4>Latent class analysis (LCA) identifies distinct groups within a heterogeneous population, but its application to accelerometry-assessed physical activity and sedentary behavior has not been systematically explored. We conducted a systematic scoping review to describe the application of LCA to accelerometry.…”
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Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma by Xiang-Ming Wang, Shang-Wei Chen, Gang Chen, Hua-Fu Zhou, Ting-Qing Gan, Jing-Jing Zeng, Zu-Yun Li

“…This study is aimed at thoroughly exploring the expression status, clinical significance, and underlying molecular mechanism of miRNA-33a-5p in lung squamous cell carcinoma (LUSC). Here, we detected miRNA-33a-5p in 20 samples from patients with LUSCs and 20 matching non-LUSC specimens by in-house quantitative real-time PCR (RT-qPCR). …”
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A Rare Case of Spontaneous Heterotopic Pregnancy at 12&nbsp;weeks of Gestation Following Natural Conception With Literature Review by Wang F, Xu Y, Dong X, Jiang P, Yu QQ

“…The complexity of clinical and laboratory findings complicates its diagnosis, necessitating a high index of suspicion for prompt intervention.Case Presentation: We reported the case of a 36-year-old woman diagnosed with heterotopic pregnancy at 12 weeks of gestation following spontaneous conception, who presented with severe abdominal pain. …”
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The current and future cancer burden in the Gulf Cooperation Council (GCC) countries by Saleh A. Alessy, Saleh A. Alqahtani, Jerome Vignat, Amid Abuhmaidan, Amani E. L. Basmi, Najla Al Lawati, Ameera Ali A‐Nooh, Wael Shelpai, Samar Alhomoud, Ali Al‐Zahrani, Freddie Bray, Ariana Znaor

“…Colorectal (14%) followed by breast cancer (9%) were the leading causes of cancer death, though the magnitude of rates of the major cancer types varied substantially across the GCC countries. Even if we assume rates in the region will remain unchanged over the next two decades, the cancer burden in the GCC will increase by 116% (Saudi Arabia) to 270% (Qatar), reaching nearly 104,000 cancer cases by the year 2040. …”
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Analytical Performances of Human Immunodeficiency Virus Type 1 RNA-Based Amplix® Real-Time PCR Platform for HIV-1 RNA Quantification by Christian Diamant Mossoro-Kpinde, Ralph-Sydney Mboumba Bouassa, Mohammad-Ali Jenabian, Serge Tonen Wolyec, Leman Robin, Mathieu Matta, Jean de Dieu Longo, Gérard Grésenguet, Laurent Andreoletti, Laurent Bélec

“…Objectives. We evaluated the performances of Amplix real-time PCR platform developed by Biosynex (Strasbourg, France), combining automated station extraction (Amplix station 16 Dx) and real-time PCR (Amplix NG), for quantifying plasma HIV-1 RNA by lyophilized HIV-1 RNA-based Amplix reagents targeting gag and LTR, using samples from HIV-1-infected adults from Central African Republic. …”
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A Clinical Mentorship and Quality Improvement Program to Support Health Center Nurses Manage Type 2 Diabetes in Rural Rwanda by Aphrodis Ndayisaba, Emmanuel Harerimana, Ryan Borg, Ann C. Miller, Catherine M. Kirk, Katrina Hann, Lisa R. Hirschhorn, Anatole Manzi, Gedeon Ngoga, Symaque Dusabeyezu, Cadet Mutumbira, Tharcisse Mpunga, Patient Ngamije, Fulgence Nkikabahizi, Joel Mubiligi, Simon Pierre Niyonsenga, Charlotte Bavuma, Paul H. Park

“…Interventions are needed to support the decentralization of services to improve and expand access to care. We describe a clinical mentorship and quality improvement program that connected nurse mentors with nurse mentees to support the decentralization of type 2 diabetes care in rural Rwanda. …”
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Factors associated with recognition at work among nurses and the impact of recognition at work on health-related quality of life, job satisfaction and psychological health: a singl... by Latifa Alahiane, Youssef Zaam, Redouane Abouqal, Jihane Belayachi

“…Objectives To describe the sociodemographic, occupational and health factors that influence nurses’ recognition at work and to examine a recognition pathway model to assess the relationship between recognition at work and health-related quality of life (HRQOL), job satisfaction, anxiety and depression.Design This is a cross-sectional observational study with prospective data collection based on a self-report questionnaire.Setting University hospital centre in Morocco.Participants The study included 223 nurses with at least 1 year of practice at the bedside in care units.Measures We included the sociodemographic, occupational and health characteristics of each participant. …”
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Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning by Jianhui Chen, Qun Li, Xiaofang Liu, Fang Lin, Yaling Jing, Jiayan Yang, Lianfang Zhao

“…Interestingly, MAN2A1 and RIBC2 may play a predominant role in the development and prognostic stratification of EC.ConclusionWe identified three key genes linking EMs and RPL, emphasizing the heterogeneity of immune infiltration in the occurrence of both diseases. …”
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Treatment of Advanced Hepatocellular Carcinoma after Failure of Sorafenib Treatment: Subsequent or Additional Treatment Interventions Contribute to Prolonged Survival Postprogressi... by Masaaki Kondo, Kazushi Numata, Koji Hara, Akito Nozaki, Hiroyuki Fukuda, Makoto Chuma, Shin Maeda, Katsuaki Tanaka

“…Sorafenib is a first-line treatment option for advanced hepatocellular carcinoma (HCC) patients; however, survival predictors upon progression have not been well characterized. In the present study, we aimed to show the efficacy of multidisciplinary therapy for patients who had failed to respond to sorafenib treatment. …”
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