Evaluating the Effect on Total Daily Insulin Dose in Adult Patients with Type 1 Diabetes Managed with Metformin and/or GLP-1 or GLP-1/GIP Receptor Agonists by Mayeesha Ahmed, Emily Pierson, Molly Webster

“…Secondary and safety endpoints were evaluated in A1c, weight, and hypoglycemia. Results: A total of 110 of 366 patients met inclusion criteria. …”
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Magnitude, risk factors and economic impacts of diabetic emergencies in developing countries: A systematic review. by Halefom Kahsay Haile, Teferi Gedif Fenta

“…<h4>Background</h4>Diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar syndrome (HHS) and severe hypoglycemia are considered as the life-threatening diabetic emergencies of diabetic patients worldwide. …”
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Symptoms and Treatment of Low Blood Glucose by Linda Bobroff

“… Low blood glucose, also called hypoglycemia, can be life-threatening for people with diabetes. …”
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Symptoms and Treatment of Low Blood Glucose by Linda Bobroff

“… Low blood glucose, also called hypoglycemia, can be life-threatening for people with diabetes. …”
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Vida Saludable: Hiperglicemia e Hipoglicemia by Jennifer Hillan, Emily Minton

“…This revised 2-page fact sheet is the Spanish-language version of FCS8820/FY885: Healthy Living: Hyperglycemia and Hypoglycemia. It was written by Jennifer Hillan and Emily Minton, and published by the UF Department of Family, Youth and Community Sciences, September 2011. …”
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Continuous Glucose Monitoring Among Patients With Type 1 Diabetes in Rwanda (CAPT1D) Phase I: Prospective Observational Feasibility Study by Jason Baker, Giacomo Cappon, Jean Claude Habineza, Corey H Basch, Steven Mey, Diana L Malkin-Washeim, Christian Schuetz, Niyonsenga Simon Pierre, Etienne Uwingabire, Alvera Mukamazimpaka, Paul Mbonyi, Sandhya Narayanan

“…CGMs have shown clinical significance by improving time in the euglycemic range, decreasing rates of hypoglycemia, and improving hemoglobin A1c1c ObjectiveThis study aims to determine the impact and feasibility of real-time CGM use among people living with type 1 diabetes (T1D) in Rwanda through assessment of sensor use, time in range, rates of hypoglycemia and hyperglycemia, HbA1c MethodsThe Continuous Glucose Monitoring Among Patients with Type 1 Diabetes in Rwanda (CAPT1D) study is a single-arm, prospective observational study conducted at the Rwandan Diabetes Association clinic in Kigali, Rwanda, aiming to assess the impact and feasibility of CGM use in Rwanda. …”
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Efficacy and safety of once-weekly semaglutide monotherapy in a young subject with Prader-Willi syndrome, obesity, and type 2 diabetes: a case report by Elisa Dinoi, Giuseppe Daniele, Giuseppe Daniele, Angela Michelucci, Fulvia Baldinotti, Fabrizio Campi, Piero Marchetti, Stefano Del Prato, Angela Dardano, Angela Dardano

“…Glucagon-like peptide 1 receptor agonists (GLP-1 RA) are attractive options, since they effectively reduce weight and improve blood glucose, without increasing the risk of hypoglycemia. However, data on their use in PWS are scarce.Case descriptionIn 2019, a 27-year-old male came to our Clinic because of first appearance of severe hyperglycemia (fasting plasma glucose 22.5 mmol/L). …”
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Vida Saludable: Hiperglicemia e Hipoglicemia by Jennifer Hillan, Emily Minton

“…This revised 2-page fact sheet is the Spanish-language version of FCS8820/FY885: Healthy Living: Hyperglycemia and Hypoglycemia. It was written by Jennifer Hillan and Emily Minton, and published by the UF Department of Family, Youth and Community Sciences, September 2011. …”
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Comparison of GLP-1 Receptor Agonists, SGLT-2 Inhibitors, and DPP-4 Inhibitors as an Add-On Drug to Insulin Combined With Oral Hypoglycemic Drugs: Umbrella Review by Sanbao Chai, Yapin Niu, Fengqi Liu, Shanshan Wu, Zhirong Yang, Feng Sun

“…Compared to placebo, GLP-1 RAs can significantly reduce body weight and basic insulin dosage, while DPP-4i and SGLT-2i have a lower risk of hypoglycemia.…”
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Polyethylene Glycol Loxenatide (PEX-168) Reduces Body Weight and Blood Glucose in Simple Obese Mice by Yuting Wu, Zeyuan Guo, Junlu Wang, Yong Wang, Daorong Wang, Ying Li, Lihua Zhu, Xiaofang Sun

“…At the 10th week, the incidence of transient hypoglycemia was 67% and 50% in the middle- and high-dose groups, respectively. …”
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Carbohydrate Counting: Meals for Diabetes by Cassie Rowe, Jamila R. Lepore, Wendy J. Dahl

“…Not enough carbohydrate can lead to low blood glucose (hypoglycemia). Too much carbohydrate can lead to high blood glucose (hyperglycemia). …”
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Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? by Ortal Resnick, Fernando Bril, Fernando Bril, Giovanna Beauchamp

“…Potential benefits need to be weighed against the risk of hypoglycemia and lack of long-term data.…”
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Carbohydrate Counting: Meals for Diabetes by Cassie Rowe, Jamila R. Lepore, Wendy J. Dahl

“…Not enough carbohydrate can lead to low blood glucose (hypoglycemia). Too much carbohydrate can lead to high blood glucose (hyperglycemia). …”
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Creating a Perioperative Glycemic Control Program by Sara M. Alexanian, Marie E. McDonnell, Shamsuddin Akhtar

“…Our approach focuses on the recognition of hyperglycemia and metabolic abnormalities, control of glucose levels via insulin infusion when needed, monitoring for hypoglycemia and a comprehensive multidisciplinary approach that provides standardized recommendations for patients at all points in care as they transition from the preoperative clinic into the operating room, and then into the hospital.…”
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A Novel CGM Metric-Gradient and Combining Mean Sensor Glucose Enable to Improve the Prediction of Nocturnal Hypoglycemic Events in Patients with Diabetes by Jingzhen Li, Xiaojing Ma, Igbe Tobore, Yuhang Liu, Abhishek Kandwal, Lei Wang, Jingyi Lu, Wei Lu, Yuqian Bao, Jian Zhou, Zedong Nie

“…Nocturnal hypoglycemia is a serious complication of insulin-treated diabetes, and it is often asymptomatic. …”
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Utilizing Technology-Enabled Intervention to Improve Blood Glucose Self-Management Outcome in Type 2 Diabetic Patients Initiated on Insulin Therapy: A Retrospective Real-World Stud... by Jian Lin, Xia Li, Shan Jiang, Xiao Ma, Yuxin Yang, Zhiguang Zhou

“…Additionally, the incidence of hypoglycemia gradually decreased and was significantly lower than the baseline level. …”
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Management of Neonatal Diabetes due to a KCNJ11 Mutation with Automated Insulin Delivery System and Remote Patient Monitoring by Ming Yeh Lee, Anna L. Gloyn, David M. Maahs, Priya Prahalad

“…Management of hyperglycemia in neonates with subcutaneous insulin is challenging because of frequent feeding, variable quantity of milk intake with each feed, low insulin dose requirements, and high risk for hypoglycemia and associated complications in this population. …”
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Rethinking the Viability and Utility of Inhaled Insulin in Clinical Practice by Lutz Heinemann, Christopher G. Parkin

“…Contributors to suboptimal adherence to insulin treatment include pain, inconvenience, and regimen complexity; however, a key driver is hypoglycemia. Improvements in the PK/PD characteristics of today’s SC insulins provide more physiologic coverage of basal and prandial insulin requirements than regular human insulin; however, they do not achieve the rapid on/rapid off characteristics of endogenously secreted insulin seen in healthy, nondiabetic individuals. …”
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The oral disposition index calculated from a meal tolerance test is a crucial indicator for evaluating differential normalization of postprandial glucose and triglyceride excursion... by Yukako Yamamoto, Takeshi Togawa, Osamu Sekine, Yuki Ozamoto, Junko Fuse, Choka Azuma, Jun Ito-Kobayashi, Yasumitsu Oe, Akeo Hagiwara, Masaki Kobayashi, Tadahiro Kitamura, Masanori Iwanishi, Akira Shimatsu, Atsunori Kashiwagi

“…However, postoperative MTT data without hypoglycemia showed no improvement in the glucose tolerance vs. pre-surgery data. …”
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Weekend-Based Parent-Group Intervention to Reduce Stress in Parents of Children and Adolescents with Type 1 Diabetes: A Pilot Study by Lucia Ferrito, Barbara Predieri, Dorina Pjetraj, Maria Cristina Alessandrelli, Manuela Pagnini, Antonio Iannilli, Monica Marino, Stefano Tombolini, Basilio Pintaudi, Giuseppe Lucisano, Fabiana Zani, Lorenzo Iughetti, Antonio Nicolucci, Valentino Cherubini

“…At baseline and after intervention, parents filled in a questionnaire including Diabetes-Related Distress (DRD), Parent Health Locus of Control Scale (PHLOC), Parent Stress Index Short Form (PSI-SF), Hypoglycemia Fear Survey-Parents (HFS-P) and Hypoglycemia Fear Survey-Parents of Young Children (HFS-P-YC), and Health Survey Short Form-36 (SF-36). …”
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