Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review by Muhammad Osama Siddiqui, Mohammad Ali Syed, Ayaan Ahmed Qureshi, Mustafa Hussain Imam, Jatin Motwani, Verkha Kumari, Arooba Siddiqui, Noor Ul Ain, Mohammed Hammad Jaber

“…Results Findings indicate that age, male gender, hypertension, and smoking significantly increase the risk of GCA‐related CIE, while factors such as anemia, higher body mass index (BMI), and elevated inflammatory markers (C‐reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) appear to have protective effects. …”
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Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study by Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu

“…Additionally, the dose-response relationship indicated a more pronounced association between higher smoking pack-years and elevated health risks, including hypertension (aOR=1.30, 95% CI: 1.24-1.36), diabetes (aOR=1.26, 95% CI: 1.20-1.33), hyperlipidemia (aOR=1.22, 95% CI: 1.16-1.28), heart disease (aOR=1.40, 95% CI: 1.26-1.54), and stroke (aOR=1.23, 95% CI: 1.10-1.36). …”
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Clinical manifestations, para-clinical features and outcome of Iranian adults with respiratory syncytial virus (RSV) infection: a report from hospitalized patients by Maryam Shafaati, Abbas Shakoori Farahani, Mohammadreza Salehi, Mohammad Arabzadeh, Helya Bolouki Azari, Arman Soleimany, Maryam Edalatifard, Vahid Salimi, Alireza Abdollahi

“…Ischemic heart disease, hypertension, and liver failure were common underlying conditions. …”
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Elevated resting heart rate in adolescent men and risk of heart failure and cardiomyopathy by Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria Åberg, Kjell Torén, Margda Waern, N. David Åberg, Annika Rosengren

“…Comparing the first and fifth quintiles of the RHR distribution, the hazard ratio (HR) for HF associated with coronary heart disease, diabetes, or hypertension was 1.25 [95% confidence interval (CI) = 1.13–1.38] after adjustment for body mass index, blood pressure, and cardiorespiratory fitness. …”
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Dyslipidemia and metabolic syndrome in childhood-onset systemic lupus erythematosus: is it time to screen? by Sirin Nuntasri, Sirirat Charuvanij, Kraisoon Lomjansook, Puthita Saengpanit, Kwanjai Chotipanang, Maynart Sukharomana

“…Patients with dyslipidemia were significantly younger at cSLE diagnosis, had higher percentage of hypertension and active features of organ involvement, lower percentage of Lupus Low Disease Activity State, more use of mycophenolate mofetil and antihypertensive medications, higher uric acid level, higher waist circumference, body mass index, body mass index z-score, and fat mass (P < 0.05). …”
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J-shaped association between dietary thiamine intake and the risk of cognitive decline in cognitively healthy, older Chinese individuals by Yuanyuan Zhang, Xianhui Qin, Chengzhang Liu, Chun Zhou, Mengyi Liu, Panpan He, Ziliang Ye, Qiguo Meng, Yuanxiu Wei, Xinyue Su

“…A stronger positive association between thiamine intake and cognitive decline was observed in those with hypertension, obesity and those who were non-smokers (all p&lt;0.05).Conclusions This study revealed a J-shaped association between dietary thiamine intake and cognitive decline in cognitively healthy, older Chinese individuals, with an inflection point at 0.68 mg/day and a minimal risk at 0.60–1.00 mg/day of dietary thiamine intake.…”
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Exploring Chronic Pain in Hemodialysis Patients: An Observational Study Based on the New IASP Classification for ICD-11 by Vittorio Schweiger, Martina Cacciapuoti, Marta Nizzero, Salvatore Simari, Gianmarco Lombardi, Leonardo Gottin, Lisa Stefani, Alvise Martini, Giustino Varrassi, Gabriele Finco, Enrico Polati, Giovanni Gambaro

“…The average age was 73.1 years; 55.5% of the patients were male; 53.7% had diabetes, and 39.2% had arterial hypertension. Of the 54 patients subjected to an in-depth evaluation, data regarding 113 pain diagnoses were extracted, particularly related to osteoarthritis, obliterating arterial disease, and low back pain with or without radiculopathy. …”
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Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study by Chunhui Zhou, Ganfeng Yang, Marc Theeboom, Hua Yang, Ruiting Zhu, Zijian Zhou, Dong Zhu

“…Notable comorbidities included hypertension (41.6%) and diabetes (33.2%), indicating a higher burden of health conditions than typical older adult populations. …”
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Assessment of vitamin D status in obese and non-obese patients: A case-control study by Salma Derbel, Lamiae Zarraa, Imane Assarrar, Nisrine Bouichrat, Siham Rouf, Hanane Latrech

“…Through our study, we aimed to look into vitamin D status in obese and non-obese patients and determine its association with hypertension, glucose levels, and lipid profiles. Patients and methods: A case-control study was laid out to compare serum Vitamin D levels between obese patients and controls. …”
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Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases by Lei Tian, Ruixiang Zhao, Xinyi Xu, Zhiwei Zhou, Xiaofang Xu, Dongmei Luo, Zhiqiang Zhou, Yu Liu, Ariel Kushmaro, Robert S. Marks, András Dinnyés, Qun Sun

“…The increased global incidence of chronic metabolic diseases, a vital threat to human health and a burden on our healthcare systems, includes a series of clinical metabolic syndromes such as obesity, diabetes, hypertension, and dyslipidemia. One of the well-known probiotic microorganisms, Lactiplantibacillus plantarum plays an important role in promoting human health, including inhibiting the occurrence and development of a variety of chronic metabolic diseases. …”
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Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer by Meng Ye, Guojie Xu, Liming Zhang, Zhihui Kong, Zhenhua Qiu

“…MTHFR, a key enzyme in folate metabolism, has been widely studied in relation to neural tube defects and hypertension, but its role in colorectal cancer remains underexplored. …”
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One-Year Review Of Reduced Fetal Movements In Izzat Ali Shah MCH Center: A Predictor Of Poor Perinatal Outcome by Humera Rani, Gulwish Salahuddin, Ayesha Naz, Noreen Majeed, Faiza Safdar, Shazia Rafique

“…Regarding medical history, anemia was seen in 31 patients (19.37%), pregnancy-induced hypertension in 20(12.5%), and 65 %( 104) has no significant medical history. …”
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Post-COVID-19 laryngo-tracheal sequelae: a comprehensive study at a tertiary care centre by Karthik P., Rupa Mehta, Ranganath T. G., Ajoy K. Behra, Atul Jindal, Himanshi Grover

“…Most common comorbidity was diabetes mellitus (DM) (62.4%) along with hypertension. The various findings were noted in 10.1% of total patients included in the study including vocal cord polyps 19.9%, vocal cord paresis 19.9%, vocal cord granulomas 8.5%, vocal nodule 5.7%, and chronic congestion of laryngeal inlet 17.1% of the patients. …”
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Aetiology and Outcomes of Thrombocytopenia in Pregnancy: A Cross-Sectional Study in a University Hospital, India by Sudha V. Hooli, Neelima Shah, Prashant Shah, Shrradha Suresh, Bali Sukeshani Sunil

“…In total, 15.8% of cases had pregnancy-induced hypertension (PIH); 3.0% had dengue; 2.3% were COVID-19 positive; 1.5% were diagnosed with haemolysis, elevated liver enzymes, and low platelets syndrome; 1.5% had immune TCP; and only one patient had leptospirosis. …”
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Elevated Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict Incident Ischemic Cardiovascular Events in a Longitudinal and Prospective AMI Aging Study by Zhao X, Zhao H, Chen R, Zhou J, Li N, Li J, Yan S, Liu C, Zhou P, Chen Y, Song L, Yan H

“…Initially, participants were stratified into three groups according to the tertile levels of FABP4, followed by further categorization based on various lipid profiles and specific inflammatory markers.Results: On follow-up (median 751 days, maximum 1506 days), a total of 158 ischemic events were recorded. 1) In multivariable models meticulously adjusted for age, gender, traditional coronary heart disease factors, Killip classification, and discharge medications, the association of elevated levels of FABP4 (Tertile 3 HR 1.618 [1.061 to 2.468], p=0.026), augmented concentrations of PTX3 (Tertile 3 HR 1.811 [1.211 to 2.710], p=0.004), or LL-37 (Tertile 3 HR 0.651 [0.433 to 0.981], p=0.040) with ischemic risk was markedly intensified. 2) Multivariate HRs associated with 1 standard deviation (SD) (mg/dL) increase in the FABP4 parameters were as follows in different subgroups. 1-SD difference in FABP4 was associated with a 23%, 23%, 21 and 29% increase in ischemic events over after fully adjusted the confounding risk factors among male, patients with hyperlipidemia, hypertension and diabetes respectively. 3) The Kaplan-Meier curve demonstrated significant differences between the tertiles of FABP4 index levels among all enrolled participants (p=0.0180).Conclusion: This study reinforces the utility of FABP4 for enhancing risk stratification specifically among older patients diagnosed with ST-elevation myocardial infarction.Keywords: FABP4, lipid profile, PTX3, LL-37, ischemic vascular events…”
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Small intestinal bacterial overgrowth syndrome and systemic inflammation in pathogenesis of hemodynamic changes at liver cirrhosis by R. V. Maslennikov, A. A. Driga, K. V. Ivashkin, M. S. Zharkova, M. V. Mayevskaya, Ch. S. Pavlov, M. G. Arslanyan, N. B. Musina, Ye. N. Berezina, V. T. Ivashkin

“…As these hemodynamic disorders aggravate the course of portal hypertension, the treatment of SIBO may reduce severity of the latter.…”
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Impact of Self-Management Clustered Care on Psychological and Birth Outcomes in Gestational Diabetes by Tang S, Wang S, Wu J, Hu S, Lu T, Zhu M, Li J, Xue F

“…Additionally, the rates of gestational hypertension (χ2=4.941), pre-term labour (χ2=3.890), and macrosomia (χ2=4.050) were reduced in the study group when compared to the control group (P< 0.05).Conclusion: SMB-CPCM can effectively control the blood glucose levels of pregnant women with GDM and improve their self-management ability, psychological status, and delivery outcomes. …”
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Predictive role of modifiable factors in stroke: an umbrella review by Yue Wang, Lu Wen, Xiaotong Wang, Man Liang, Fanxin Zeng, Yuetian Yang, Fangfang Nie, Mengke Shang, Na Ta, Lanxin Ou, Zhibin Yang, Wanyang Liu

“…Suggestive evidence mainly included dietary approaches to stop hypertension (DASH) diet, vitamin C, magnesium, depression and particulate matter 2.5. …”
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Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort by Kristin Ottarsdottir, Åsa Tivesten, Claes Ohlsson, Ying Li, Margareta Hellgren, Ulf Lindblad, Bledar Daka

“…Methods This is an observational cross-sectional study on the Vara-Skövde cohort, a Swedish population-based study for longitudinal surveillance of the development and progress of type 2 diabetes and hypertension. The participants were physically examined in 2002–2005 and sex hormones were analysed with liquid chromatography-tandem mass spectrometry assay (LC-MS/MS). …”
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Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19 by Juan Antonio Suárez-Cuenca, José Fernando Flores-Zaleta, Leslie Andrea Corona-Rojas, Pablo Guzmán-Rullán, Luis Alfonso Camacho-Barajas, Uzziel Aguilera-Ontiveros, Alberto Melchor-López, Alejandro González-Mora, Perla Marlene Guzmán-Ramírez, Janicia Rodríguez-Solis

“…Results One-hundred and four patients mean aged 55 years old, 66% males, main comorbidities obesity, hypertension and diabetes mellitus. Larger lung damage was associated with older age, male gender and higher pro-inflammatory mediators like leukocytes and ferritin; whilst consolidation pattern was related to higher Body Mass Index. …”
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